[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure : ← →

chr1:40,748,755-42,406,344

Best TWAS P=4.98e-19 · Best GWAS P=6.49e-15 conditioned to 0.72

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	The Cancer Genome Atlas	Thyroid Carcinoma	SCMH1	0.07	0.08	blup	97	0.07	2.5e-07	7.79	-8.9	5.0e-19	-0.89	0.01	0.99	TRUE
5	GTEx	Nerve Tibial	SCMH1	0.16	0.03	enet	24	0.07	1.6e-05	7.75	-7.8	5.4e-15	-0.77	0.01	0.99	FALSE
7	The Cancer Genome Atlas	Prostate Adenocarcinoma	SCMH1	0.03	0.03	lasso	2	0.02	6.2e-03	7.34	-7.3	2.2e-13	-0.63	0.08	0.58	FALSE
4	GTEx	Lung	CTPS1	0.06	0.04	lasso	3	0.04	2.4e-04	5.72	5.9	3.1e-09	0.69	0.20	0.65	FALSE
6	The Cancer Genome Atlas	Brain Lower Grade Glioma	SCMH1	0.04	0.01	enet	7	0.02	2.5e-03	-0.59	-5.9	3.2e-09	-0.29	0.05	0.20	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	CTPS1	0.26	0.11	lasso	6	0.08	1.6e-03	5.98	5.6	2.2e-08	0.79	0.22	0.27	FALSE
2	GTEx	Breast Mammary Tissue (Female)	CTPS1	0.12	-0.01	lasso	4	-0.01	7.5e-01	4.80	5.3	1.2e-07	0.42	0.04	0.07	FALSE
1	GTEx	Artery Aorta	CTPS1	0.10	0.00	enet	8	0.00	4.6e-01	4.85	5.2	2.1e-07	0.50	0.10	0.12	FALSE