Hub : Genes

SCMH1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0930	0.0290	1.9e-04	0.085	NA	0.080	NA	0.077	1.8e-07	NA	4.0e-07	NA	6.7e-07
2	GTEx	Artery Aorta	0.2690	0.0670	1.8e-06	0.114	NA	0.074	NA	0.102	7.4e-07	NA	7.0e-05	NA	3.0e-06
3	GTEx	Artery Tibial	0.0854	0.0312	1.7e-03	0.008	NA	-0.001	NA	0.004	7.3e-02	NA	3.8e-01	NA	1.4e-01
4	GTEx	Colon Transverse	0.1620	0.0700	9.9e-03	0.066	NA	0.055	NA	0.041	4.7e-04	NA	1.2e-03	NA	5.0e-03
5	GTEx	Esophagus Muscularis	0.1760	0.0480	1.1e-05	0.025	NA	0.101	NA	0.052	1.1e-02	NA	1.1e-06	NA	4.0e-04
6	GTEx	Nerve Tibial	0.1555	0.0428	6.5e-06	0.033	NA	0.068	NA	0.037	2.0e-03	NA	1.6e-05	NA	1.1e-03
7	TCGA	Brain Lower Grade Glioma	0.0406	0.0245	3.0e-03	0.013	0.011	0.019	NA	0.012	1.1e-02	1.7e-02	2.5e-03	NA	1.5e-02
8	TCGA	Prostate Adenocarcinoma	0.0310	0.0199	7.1e-03	0.026	0.015	0.004	NA	0.017	8.4e-04	8.4e-03	1.1e-01	NA	6.2e-03
9	TCGA	Testicular Germ Cell Tumors	0.3460	0.1250	2.2e-04	0.138	0.137	0.116	NA	0.108	1.4e-05	1.5e-05	7.0e-05	NA	1.3e-04
10	TCGA	Thyroid Carcinoma	0.0710	0.0300	5.0e-07	0.076	0.070	0.059	NA	0.063	7.0e-08	2.5e-07	2.2e-06	NA	1.0e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	1.3	2.0	7.1	1.0	1.2	0.6	0.2	-0.7	-1.6	-0.7	-0.8	2.5	-2.7
Bipolar Disorder or Schizophrenia	1.6	3.8	14.0	0.2	0.3	0.4	-0.3	-0.8	-3.0	-2.0	-1.7	2.7	-3.7
Depressed Affect (Nagel 2018)	0.2	0.4	1.9	0.0	-0.1	-0.6	1.4	-0.4	0.9	-0.0	-0.3	-1.0	-0.3
Depression (Nagel 2018)	0.6	0.9	2.6	-0.3	-0.8	-0.0	1.6	0.5	-0.9	-1.4	-1.3	-0.3	-1.0
Intelligence (Savage-Jansen 2018)	4.1	12.6	34.8	2.7	3.6	5.9	-0.7	5.4	4.3	2.1	0.9	2.3	3.5
Neuroticism (Nagel 2018)	0.3	0.6	3.9	0.1	0.5	-0.5	2.0	-0.0	0.9	-0.2	0.3	-0.7	-0.5
Schizophrenia (2018)	1.1	2.4	7.1	-0.5	-0.6	0.1	-0.5	-0.5	-2.5	-2.0	-1.6	1.5	-2.7
Schizophrenia vs Biploar Disorder	0.8	1.1	3.7	-1.2	-1.9	-0.7	0.4	-0.6	0.7	-0.3	1.1	-0.7	1.6
Worry (Nagel 2018)	0.4	0.8	3.2	0.4	1.0	-0.4	1.8	0.5	1.2	0.5	1.0	-0.1	0.1
Alzheimer’s Disease (in mother)	1.4	1.6	6.0	0.6	2.4	2.4	-0.1	1.7	0.6	-0.5	-0.5	-1.0	0.1
Alzheimer’s Disease (in father)	3.3	3.6	7.3	1.4	1.8	2.1	1.2	1.3	2.1	1.4	2.3	-2.7	2.2
Alzheimer’s Disease (including proxy)	2.0	2.9	7.3	1.2	2.6	2.7	1.3	1.8	1.5	0.3	1.0	-1.9	1.3
Crohns Disease (2017)	0.4	0.8	2.0	1.3	1.4	0.9	-0.4	-0.7	-1.2	0.6	-0.3	0.2	-1.0
Irritable Bowel Disease (IBD)	0.5	1.2	3.9	0.7	0.9	-0.0	-1.3	-2.0	-1.3	0.9	0.6	0.2	-1.5
Ulcerative Colitis (UC)	0.5	1.0	5.3	-0.3	-0.0	-0.6	-0.6	-2.3	-0.7	0.8	1.2	0.1	-1.1
Major Depression (MDD)	0.6	0.8	4.4	-0.6	-0.7	0.4	2.1	0.5	1.1	-0.1	0.4	0.0	0.8
Reaction Time	1.8	3.5	7.8	-2.8	-2.3	-2.7	2.0	-1.6	0.7	0.5	1.7	-1.3	1.6
Verbal and Numeric Reasoning (VNR)	5.1	12.2	37.4	2.8	3.5	5.1	1.2	6.1	3.9	1.8	0.3	2.3	3.7
Breast Cancer	1.3	3.2	6.4	-2.5	-2.3	-2.4	-1.8	-1.9	-0.2	-2.2	-1.4	-0.4	-1.0
Ovarian Cancer	1.4	1.9	6.7	-2.6	-2.0	-1.6	0.9	-1.9	0.4	-1.0	0.2	0.1	0.4
Prostate Cancer	0.7	1.0	3.4	-0.1	0.9	1.0	1.2	1.3	-0.1	-1.0	-0.7	1.8	-0.6
Age at First Birth	0.4	0.6	3.1	-0.5	0.2	0.4	-0.1	0.3	-0.2	-1.2	-0.2	1.8	-0.5
Bipolar Disorder (2011)	1.5	1.5	6.2	-0.3	0.1	-0.6	-0.1	-1.3	-1.6	-1.0	-1.4	0.8	-2.5
Body Mass Index (BMI) (2010)	2.1	2.9	6.5	-1.9	-2.1	-1.1	-1.4	-2.0	-1.1	-2.5	-1.7	-0.4	-1.7
Coronary Artery Disease (CAD)	1.2	1.4	5.8	-0.5	-1.0	-0.6	-1.4	-0.7	0.4	1.4	1.1	-2.4	0.8
Crohns Disease (2012)	0.3	0.4	1.3	0.4	0.1	0.8	-0.3	-0.9	-1.1	-0.0	-0.7	0.3	-0.7
Mean Putamen Volume	0.6	0.7	1.8	-0.8	-0.8	-0.4	-0.8	0.9	-0.3	-1.3	-1.3	0.7	-0.5
Fasting Glucose	0.6	0.7	2.4	-1.5	-0.9	-0.9	1.4	-0.1	0.2	-0.1	-0.2	0.4	1.1
HbA1C	0.6	0.7	3.4	-0.4	-1.0	-1.0	1.9	-0.2	0.1	-0.4	-0.7	-0.5	0.4
HDL Cholesterol	0.3	0.4	1.0	-0.8	-0.3	-0.8	0.1	0.5	0.8	-0.4	0.9	-0.5	1.0
LDL Cholesterol	0.4	0.7	2.8	-0.4	-0.7	-1.7	0.6	-0.6	0.1	0.1	0.6	-1.4	0.3
Lupus	2.0	3.1	8.5	2.2	2.5	2.9	1.4	1.7	0.6	1.6	1.6	-0.7	0.7
Neuroticism (2016)	1.1	1.6	4.3	-0.5	0.3	-0.2	2.1	0.8	2.1	-0.1	1.7	-0.7	1.7
Primary Biliary Cirrhosis	1.9	2.6	6.1	-1.8	-2.2	-1.4	-1.3	-2.5	-0.8	-2.0	-1.2	-0.9	-1.2
Rheumatoid Arthritis	0.2	0.3	1.1	-0.1	-0.4	-0.5	-0.1	0.4	-0.1	1.1	0.8	-0.4	0.3
Schizophrenia (2014)	1.7	3.8	10.9	-0.1	-0.5	0.3	-1.0	-0.5	-3.0	-2.6	-2.0	2.4	-3.3
Triglycerides	0.2	0.3	2.1	-0.3	-0.1	0.0	-0.4	-0.4	0.4	0.5	0.3	-1.4	0.6
Type 2 Diabetes (T2D) (2012)	2.5	2.9	7.5	-1.0	-1.0	-0.3	1.3	-1.0	2.0	1.0	2.7	-2.5	2.3
Ulcerative Colitis	1.1	1.7	5.4	-1.5	-1.3	-1.8	-1.7	-2.3	-0.4	0.1	0.6	-0.3	-0.6
Blood Eosinophil Count	0.3	2.3	5.8	2.4	1.6	1.9	0.7	1.5	-1.7	-0.0	-1.6	1.2	-1.4
Blood Platelet Count	1.4	16.6	50.7	-0.4	2.2	2.0	2.4	1.0	7.1	3.5	6.0	-0.9	7.1
Blood Red Count	0.4	3.7	9.2	2.0	2.7	3.0	0.4	3.0	1.0	0.3	-1.6	2.0	0.0
Blood White Count	1.9	13.9	24.1	2.9	4.3	4.0	2.2	4.0	4.9	3.9	3.7	-0.0	4.6
Heel T-Score	3.7	29.6	94.5	-0.5	-0.3	0.5	2.1	0.0	6.7	5.3	9.7	-7.2	8.4
BMI	0.2	1.4	3.8	1.2	0.5	0.9	-0.9	0.7	-0.8	-0.9	-1.9	1.8	-1.4
Height	9.7	187.2	484.0	-4.5	-6.6	-4.5	-8.6	-7.6	-17.2	-15.5	-22.0	13.5	-21.3
Waist Hip Ratio (WHR)	0.5	2.2	5.8	0.9	1.3	2.4	1.5	2.2	-0.8	-1.4	-1.5	1.2	-0.5
Systolic Blood Pressure	3.7	18.3	34.2	4.5	4.7	5.3	1.4	3.6	3.7	5.8	5.3	-2.0	4.1
Smoking Status	1.0	2.5	7.6	-1.3	-1.3	0.2	1.2	-0.3	1.8	0.4	2.0	-2.8	2.3
Allergy or Eczema	0.3	0.8	2.6	1.0	1.0	0.7	0.7	1.2	1.6	0.7	0.5	-0.7	0.5
Cardiovascular Disease	1.0	3.3	7.0	2.4	2.3	2.6	-2.3	1.9	1.2	1.3	1.4	0.9	0.1
Hypothyroidism (self reported)	0.7	1.7	7.7	0.8	-0.0	-0.1	0.6	-0.3	-2.1	-0.5	-1.3	1.1	-2.8
Respiratory disease	0.7	1.5	3.8	-0.8	-0.9	-0.4	-0.9	-0.6	-2.0	-1.2	-1.7	-0.2	-1.9
Type 2 Diabetes (T2D) (2018)	0.1	0.3	0.8	-0.2	0.4	-0.3	-0.2	0.7	0.9	0.1	-0.6	-0.5	0.7
Lung FEV1/FVC ratio	0.6	3.0	11.0	0.2	0.4	-0.1	-1.0	0.3	2.0	1.7	3.2	-0.4	3.3
Lung FVC	2.3	11.9	32.5	-1.6	-2.4	-2.1	-2.6	-3.8	-5.7	-3.4	-3.2	0.7	-5.5
Neuroticism	0.4	1.1	3.5	-0.5	0.1	0.0	1.9	-0.2	1.6	0.9	1.2	-1.2	0.6
Chronotype (morning person)	1.1	2.6	7.5	-0.3	0.1	-1.1	0.6	-1.3	1.5	1.0	2.7	-2.7	2.1
Hair Pigment	0.0	0.5	1.8	0.1	0.4	0.9	0.1	-1.3	-0.7	-0.2	-0.6	1.3	-0.2
Tanning	0.3	3.5	11.6	-1.7	-1.8	-3.4	-1.6	-1.8	-0.5	-1.6	-1.9	-0.2	-2.4
Hand grip strength (left)	3.0	7.9	22.4	-2.0	-2.2	-0.4	-0.9	-1.5	-3.7	-3.5	-4.7	2.1	-3.8
Number of treatments/medications taken	1.3	2.3	7.7	0.9	0.9	1.1	0.1	1.3	2.2	0.9	1.6	-2.8	1.6
Average weekly spirits intake	0.5	0.7	1.5	0.2	0.9	0.1	-0.6	0.9	1.2	1.0	0.4	-0.8	1.2
Sensitivity / hurt feelings	1.8	3.1	9.6	-2.2	-2.3	-3.1	1.1	-2.8	0.2	-0.6	0.9	-0.8	-0.1
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.9	0.1	0.0	0.1	1.4	0.5	-0.5	-1.0	-0.9	0.1	-1.1
Hearing difficulty/problems: Yes	0.4	0.6	1.5	-0.1	-0.3	0.6	-0.9	0.9	-0.0	-1.2	-1.1	0.6	-0.7
Relative age of first facial hair	2.6	5.4	17.3	-0.7	0.6	1.0	3.3	2.1	3.5	0.7	2.3	-1.4	4.2
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	3.0	1.0	0.6	0.9	-0.4	0.8	-1.3	-0.9	-1.7	0.4	-1.7
Ever used hormone-replacement therapy (HRT)	2.8	3.5	12.0	-2.0	-1.6	-0.2	-0.6	-1.2	-1.7	-3.5	-2.7	-0.8	-2.1
Ever had hysterectomy (womb removed)	1.2	1.4	2.6	-0.1	-0.9	-1.3	-1.2	-1.4	-1.6	-1.2	-0.7	-0.6	-1.6
Systolic blood pressure, automated reading	3.4	9.8	19.1	3.4	3.3	3.5	0.5	2.7	3.0	4.4	3.9	-1.2	3.4
Eye problems/disorders: Diabetes related eye disease	2.4	2.6	7.0	-0.4	-2.1	-2.6	-0.5	-0.1	-1.7	-1.9	-2.1	1.0	-1.4
Angina	0.9	1.2	4.1	0.8	0.1	-0.6	-1.7	-0.0	-1.6	-0.2	-1.1	-0.2	-2.0
Medication for hormone replacement therapy	1.2	1.3	2.6	-0.9	-0.4	-1.1	-1.3	-0.3	-1.6	-1.2	-1.5	1.0	-1.3
Vitamin and mineral supplements	0.6	0.9	2.7	-0.8	-0.2	-0.8	-0.1	-0.9	0.8	1.6	1.3	0.8	1.0
Supplements: Zinc	1.1	1.2	3.6	-1.2	-1.2	0.9	1.4	0.4	-0.9	-1.9	-1.2	-0.8	-0.5
Medication: Co-codamol	0.2	0.2	1.1	0.1	-0.0	-0.0	-0.8	0.7	0.1	-0.0	-0.1	-1.1	0.1
Medication: Metformin	0.2	0.3	1.3	-0.1	0.2	0.0	0.9	1.1	0.6	0.5	-0.8	0.4	0.1
Diabetes (father)	0.6	0.8	3.6	-0.6	0.2	-0.9	-0.6	0.2	0.4	-1.1	-1.9	0.9	0.3
Diabetes (mother)	0.7	0.9	5.1	0.9	0.4	0.8	0.5	-0.4	0.3	0.9	1.0	-2.3	0.4
Severe depression (siblings)	1.2	1.3	4.7	1.3	1.2	1.5	1.0	0.8	0.7	0.0	1.0	-2.2	0.4
Pack years adult smoking proportion	0.6	0.9	1.8	-0.6	-1.2	-1.2	1.3	-0.7	0.4	1.0	1.1	0.2	1.2
Impedance of leg (right)	1.2	5.7	17.3	-0.3	0.6	0.4	2.9	1.9	3.6	1.8	2.8	-1.6	4.2
Leg fat-free mass (left)	7.3	38.7	112.4	-0.3	-1.6	-0.3	-4.9	-3.1	-8.2	-6.2	-9.7	6.3	-10.6
Trunk fat percentage	0.4	1.6	3.2	1.0	1.3	1.8	-1.1	1.8	1.8	0.0	-0.9	1.0	0.8
Hand grip strength (right)	5.4	14.5	40.6	-2.8	-3.2	-1.7	-1.3	-2.4	-4.6	-4.8	-6.4	2.8	-4.9
Townsend deprivation index at recruitment	0.9	1.2	6.6	0.8	0.2	2.6	0.2	1.2	0.2	1.0	0.8	0.6	1.0
Current tobacco smoking	1.3	2.2	5.6	-0.1	-0.1	1.1	2.4	1.1	1.5	0.9	2.3	-1.7	1.6
Average weekly fortified wine intake	0.8	0.9	3.5	0.6	0.6	0.6	1.5	1.9	0.1	0.4	-0.0	1.5	0.1
Maternal smoking around birth	0.7	0.9	3.9	-0.1	-0.9	-0.7	-0.6	-1.0	-0.8	-1.2	-0.1	-2.0	-0.9
Fed-up feelings	0.1	0.3	0.6	-0.8	-0.7	-0.7	0.3	-0.7	0.6	-0.4	0.2	0.2	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.2	-0.2	-0.2	0.6	0.2	0.8	-0.2	-1.1	-0.7	0.5	-0.7
Relative age voice broke	5.2	7.9	25.4	-0.3	1.5	1.5	1.9	2.5	4.9	1.9	3.0	-1.7	5.0
Taking other prescription medications	0.6	0.9	2.9	0.9	0.9	1.1	0.3	1.1	0.8	0.8	0.8	-1.7	0.0
Age when periods started (menarche)	2.3	5.4	18.7	-0.1	1.5	0.9	2.1	2.4	4.0	1.8	1.6	-0.4	4.3
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.0	0.2	0.5	0.2	-1.1	0.3	-1.1	-0.4	-0.9	1.4	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	2.4	5.5	17.7	-1.7	-0.9	0.1	-0.2	-1.9	2.9	1.1	4.2	-3.5	2.8
Tinnitus: Yes, but not now, but have in the past	1.9	2.1	10.8	-0.6	-0.4	0.2	0.7	0.8	3.3	0.4	1.3	-1.0	2.3
Qualifications: CSEs or equivalent	1.8	2.4	12.7	0.2	0.1	-0.7	0.0	-1.4	-0.0	1.6	2.5	-3.6	0.0
Serious illness, injury or assault to yourself	0.8	1.0	3.7	0.6	0.4	0.5	-0.0	0.6	-1.4	-0.7	-1.6	0.5	-1.9
High blood pressure	0.6	1.7	3.5	1.2	1.4	1.9	-1.6	1.3	1.6	0.8	1.2	0.1	0.8
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.8	-0.1	-0.3	-0.1	0.9	0.2	1.3	0.0	0.5	-1.1	0.5
Multivitamins +/- minerals	0.7	0.9	2.1	1.2	1.2	1.5	0.1	1.1	0.3	-1.0	-0.2	-1.4	-0.1
Stomach or abdominal pain in last month	0.5	0.6	2.5	0.4	0.4	-0.1	-1.6	0.0	0.2	-1.0	0.0	-0.9	-1.4
Supplements: Glucosamine	0.6	0.8	4.5	0.4	0.7	1.1	-0.9	-0.1	0.6	-0.2	0.9	-2.1	0.3
Diverticular disease/diverticulitis (self-reported)	1.8	2.1	4.3	1.7	1.7	2.1	-2.1	1.9	-0.4	0.2	-1.1	1.3	-0.5
Medication: Atenolol	0.6	0.8	3.5	-0.0	0.0	0.5	-1.9	-0.5	-0.9	-0.8	0.1	-1.5	-0.6
Medication: Levothyroxine sodium	0.3	0.5	1.5	0.8	1.0	0.7	1.2	0.8	0.3	0.2	-0.1	-0.2	-0.4
Sitting height	9.3	65.8	201.6	0.0	-2.3	-0.7	-5.4	-4.8	-11.5	-6.5	-11.8	9.2	-14.2
Chronic bronchitis/emphysema (father)	0.7	0.8	2.3	-0.5	-0.0	-0.1	-1.5	0.1	-0.8	-0.8	-1.2	1.3	-1.0
High blood pressure (mother)	0.7	1.0	3.5	-0.6	-0.5	-1.0	0.8	-0.9	1.9	-0.1	1.2	-0.2	1.4
Body mass index (BMI)	0.2	0.9	2.3	1.2	0.7	0.7	-1.5	0.2	-0.2	-0.4	-1.4	0.8	-1.1
Impedance of leg (left)	1.1	5.4	15.5	-0.4	0.4	0.0	3.1	1.6	3.5	1.5	2.7	-2.0	3.9
Leg predicted mass (left)	7.2	38.3	110.2	-0.3	-1.7	-0.4	-4.9	-3.2	-8.2	-6.1	-9.7	6.2	-10.5
Trunk fat mass	1.1	4.7	16.7	0.4	0.2	0.9	-2.3	0.0	-1.4	-2.2	-4.1	2.9	-3.0
Waist circumference	1.5	5.5	14.0	1.6	1.1	1.6	-2.0	0.3	-2.2	-1.9	-3.7	2.9	-3.7
Number of incorrect matches in round	0.9	1.5	6.5	-1.1	-0.9	-0.6	0.4	-1.1	-2.5	-0.4	-0.7	1.5	-1.5
Past tobacco smoking	0.4	0.8	4.9	0.8	0.7	0.1	-0.2	1.0	-0.4	0.0	-0.1	2.2	-0.8
Alcohol usually taken with meals	1.3	2.1	7.2	-1.2	-0.9	-1.0	-0.2	0.5	-0.2	-1.5	-2.5	2.7	-1.5
Nervous feelings	0.6	1.1	4.7	0.3	1.2	-0.0	0.2	0.5	2.2	0.6	1.6	0.1	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.2	0.2	-0.3	-0.3	1.5	0.4	-0.9	-0.2	-0.5	-0.8	-0.8
Hearing difficulty/problems with background noise	0.5	0.8	3.3	-0.7	-0.9	-0.0	-1.7	0.0	0.3	-1.8	-0.6	-0.3	-0.3
Hair/balding pattern: Pattern 2	0.8	1.0	2.4	-0.1	0.5	0.5	-1.3	-0.1	1.1	1.2	1.6	-1.0	1.2
Had menopause	0.3	0.4	1.4	-0.7	-0.6	-1.2	-0.4	-0.2	0.0	-0.8	-0.4	0.6	0.3
Had other major operations	0.8	1.0	3.7	-0.3	-0.3	0.1	0.1	0.6	0.0	-1.8	-1.9	1.6	-0.3
Forced vital capacity (FVC)	10.3	39.8	127.7	-0.9	-2.6	-1.9	-3.5	-3.8	-9.6	-6.3	-9.3	3.9	-11.3
Heel bone mineral density (BMD) T-score, automated (right)	2.7	6.2	21.2	-1.9	-0.9	0.0	-0.6	-2.5	2.7	1.1	4.6	-3.8	2.5
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.2	0.6	0.0	0.7	-0.3	1.2	-0.3	-0.4	-1.5	-0.4	-0.9
Qualifications: None of the above	2.2	4.8	9.1	-0.8	-2.6	-2.6	-2.3	-3.0	-3.0	-1.5	-1.0	-0.6	-2.6
Financial difficulties in last 2 years	0.9	1.3	3.1	0.7	1.0	0.6	1.1	1.0	1.5	1.2	1.0	-0.8	1.8
Mouth/teeth dental problems	1.1	1.7	4.9	-0.6	0.5	1.0	0.0	1.0	2.2	1.6	1.6	0.4	2.0
Heart attack	1.2	1.5	5.3	0.7	-0.4	0.1	-1.2	-0.4	-2.2	-0.8	-1.2	-0.9	-2.3
Allergy	0.2	0.5	2.7	0.8	1.0	0.5	-0.1	0.8	-0.2	0.2	-0.0	1.6	0.5
Pain all over the body in last month	0.4	0.4	1.2	0.2	0.4	0.7	0.9	0.5	-1.1	-0.5	-0.3	0.3	-0.9
Diabetes (self-reported)	0.2	0.3	0.8	0.1	0.6	-0.3	-0.1	0.9	0.7	0.7	-0.2	0.2	0.8
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	3.1	-0.6	-1.0	-0.9	0.2	0.5	1.2	0.2	1.8	-1.4	0.8
Medication: Ramipril	0.5	0.6	3.0	-0.6	-0.9	-1.1	-1.7	-0.8	-0.0	0.1	0.0	-0.1	-0.4
Medication: Simvastatin	0.2	0.3	0.9	-0.6	-0.0	-0.0	-0.4	-0.1	0.9	-0.3	0.1	-0.8	0.9
Fluid intelligence score	2.9	6.0	16.4	1.3	2.3	4.0	1.5	3.7	3.3	0.7	-0.5	1.4	2.6
Illnesses of siblings	0.8	1.2	4.6	-0.5	0.3	0.1	-1.4	-0.5	-0.9	-0.8	-2.1	1.7	-0.7
Neuroticism score	0.3	0.6	2.3	-0.3	0.4	-0.2	1.5	0.0	1.5	0.1	0.9	-0.5	0.2
Weight	5.0	24.4	68.5	0.2	-0.9	-0.1	-4.3	-2.2	-6.0	-4.8	-8.1	5.2	-8.3
Impedance of arm (right)	2.6	12.3	30.8	1.3	2.6	2.6	1.9	3.6	5.1	3.7	4.4	-1.2	5.5
Arm fat percentage (right)	0.6	2.2	4.9	1.7	1.8	2.1	-0.9	1.8	2.2	1.0	0.4	-0.3	1.4
Trunk fat-free mass	11.6	66.6	196.0	-1.6	-3.6	-2.3	-5.0	-5.5	-11.2	-8.4	-12.2	7.0	-14.0
Hip circumference	2.0	8.7	24.1	1.9	1.0	1.4	-3.1	-0.4	-2.7	-1.8	-4.8	3.5	-4.9
Time employed in main current job	0.8	0.9	4.4	0.7	0.9	0.3	-2.1	0.9	0.6	0.1	0.2	-1.2	0.8
Alcohol intake versus 10 years previously	1.1	1.6	6.2	-0.7	-2.3	-2.5	-0.1	-0.6	0.2	0.3	-0.2	2.0	0.2
Father’s age at death	0.9	1.2	4.5	1.5	1.6	2.1	0.2	1.3	0.6	-0.3	-0.7	-0.4	0.1
Worrier / anxious feelings	0.6	1.2	4.7	0.9	1.1	0.3	0.2	0.6	-1.0	-0.9	-1.3	1.1	-2.2
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	2.8	0.2	-0.1	0.3	-1.3	0.1	-0.8	-0.4	-1.2	-0.5	-1.7
Falls in the last year	0.8	1.1	3.6	1.1	0.7	1.1	-1.9	1.3	-1.1	0.4	-0.7	0.2	-0.8
Hair/balding pattern: Pattern 3	1.6	2.4	4.7	-0.8	-2.0	-1.6	0.9	-1.1	-2.0	-1.8	-1.8	0.1	-2.2
Number of live births	0.6	0.8	2.6	-0.4	-0.9	-1.6	0.1	-0.3	-0.5	-1.6	-1.2	0.2	-0.5
Forced expiratory volume in 1-second (FEV1)	7.2	24.4	75.1	-0.6	-1.8	-1.2	-2.7	-3.3	-7.7	-5.2	-7.1	3.0	-8.7
Pulse rate	0.8	1.3	4.3	-0.4	-0.2	0.3	1.1	1.4	2.1	0.8	1.0	-1.0	1.7
Happiness	0.5	0.7	2.0	0.6	0.6	0.6	0.9	1.4	0.3	-0.8	-1.2	0.6	-0.5
Noisy workplace	1.0	1.2	3.6	1.4	0.9	0.8	-1.5	0.7	-0.0	1.2	0.7	-1.9	0.0
Qualifications: A levels/AS levels or equivalent	2.7	6.0	12.9	1.5	2.9	3.5	2.2	3.6	2.3	0.1	0.2	3.1	2.0
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.5	0.7	0.5	-0.9	-0.4	1.2	0.4	0.2	0.2	-0.9	0.2
Mouth/teeth dental problems: Dentures	0.5	0.8	2.5	1.6	1.0	0.3	0.0	1.5	-0.8	0.7	-0.8	0.4	-1.0
Asthma	0.1	0.1	0.4	-0.1	-0.3	0.4	0.0	0.1	-0.3	-0.2	0.2	-0.6	-0.5
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	4.4	1.2	1.4	0.4	1.6	0.4	2.1	0.9	0.8	0.7	1.6
Medication: Cholesterol lowering	0.5	0.8	4.8	-0.4	-0.1	-0.2	-2.2	0.3	0.9	-0.1	-0.4	-1.3	0.6
Depression (self-reported)	0.2	0.3	1.5	0.3	0.0	0.1	1.2	0.2	-0.1	-0.8	0.1	0.4	-0.1
Medication: Lansoprazole	2.0	2.3	6.1	-0.1	0.2	-0.6	-2.4	0.5	-0.7	-2.4	-2.5	-0.1	-2.0
Prospective memory result	0.8	0.9	3.8	1.8	0.8	1.0	-0.0	1.9	0.4	0.5	-0.2	0.2	0.5
Lung cancer (father)	0.7	0.8	2.1	-1.4	-1.0	-1.1	0.4	-1.1	-0.4	-0.3	0.9	-1.2	0.2
Illnesses of mother	0.6	0.7	3.5	0.7	0.0	0.7	-0.3	-0.3	-1.9	0.7	0.1	0.6	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	8.5	27.1	79.4	-0.9	-2.0	-1.5	-3.5	-3.3	-7.8	-5.9	-7.3	3.3	-8.9
Pulse wave Arterial Stiffness index	0.8	1.0	5.7	-0.4	0.2	0.4	2.4	0.9	-0.0	-0.0	-1.0	1.2	0.4
Impedance of arm (left)	3.0	14.0	33.6	1.6	3.0	3.0	2.4	3.9	5.5	3.8	4.3	-0.9	5.8
Arm fat mass (right)	0.9	3.5	11.2	0.9	0.5	1.2	-2.1	0.2	-1.5	-1.8	-3.3	1.8	-2.9
Trunk predicted mass	11.6	66.3	196.0	-1.6	-3.6	-2.4	-4.9	-5.6	-11.2	-8.3	-12.2	6.9	-14.0
Standing height	10.2	100.9	282.2	-2.2	-3.8	-2.0	-6.1	-5.4	-13.3	-10.3	-15.7	10.4	-16.8
Length of working week for main job	1.0	1.1	2.8	0.8	1.0	0.3	-0.1	0.8	-1.2	0.3	-1.6	-1.2	-1.7
Exposure to tobacco smoke at home	1.0	1.1	1.9	-1.3	-1.3	-0.6	-1.2	-1.4	-1.3	-0.9	-0.4	-1.0	-0.4
Breastfed as a baby	0.5	0.6	2.8	0.1	-0.3	-1.1	-0.0	-0.2	0.7	1.7	0.9	-0.3	0.5
Tense / ‘highly strung’	1.6	2.7	6.6	1.6	2.6	1.4	1.6	2.0	1.8	2.1	1.1	-0.1	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	3.0	1.1	1.0	0.8	0.5	1.7	-0.9	-1.7	-1.6	0.7	-1.2
Hair/balding pattern: Pattern 4	2.7	6.6	22.2	-2.3	-0.9	-1.8	1.1	-1.8	-0.5	-3.2	-4.0	4.7	-1.9
Birth weight of first child	1.8	3.3	10.8	-0.7	-1.7	-1.5	-0.1	-1.8	-3.3	-0.9	-2.5	0.2	-2.6
Peak expiratory flow (PEF)	2.1	5.0	14.1	0.5	0.4	1.6	-1.0	-0.3	-2.9	-2.4	-3.5	2.4	-3.8
Pulse wave reflection index	1.0	1.2	8.8	-0.5	-0.0	-0.8	3.0	-0.4	0.6	0.7	0.3	0.4	0.9
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.0	1.4	0.7	0.0	0.5	0.7	-0.4	0.6	-0.6	-0.8	-0.5
Loud music exposure frequency	0.3	0.3	0.7	-0.4	-0.4	0.5	0.7	-0.3	0.5	-0.4	0.8	-0.6	0.6
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	5.7	1.3	2.0	1.5	0.6	2.4	1.2	1.2	0.2	1.7	0.8
Mouth/teeth dental problems: Bleeding gums	1.1	1.5	4.3	1.1	0.4	0.5	0.4	0.5	-1.4	-2.0	-2.1	0.8	-1.4
Blood clot in the leg (DVT)	1.9	2.4	5.8	-0.9	-1.1	-1.1	-1.0	-0.6	-2.0	-1.7	-2.4	1.3	-2.3
Medication: Paracetamol	1.5	2.5	6.3	0.5	0.8	1.2	0.6	1.1	2.5	0.7	2.3	-2.2	2.1
Headache pain in last month	1.4	2.3	8.0	-0.5	-0.8	-0.9	1.4	-0.1	2.8	0.2	1.8	-1.4	2.5
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	6.0	-0.2	-0.5	-0.5	2.5	-0.9	-1.8	-0.7	-1.2	2.0	-1.5
Glaucoma (self-reported)	0.6	0.7	2.8	-0.2	0.2	0.2	-1.7	-1.0	-0.8	-1.0	-0.5	0.7	-0.9
Gout (self-reported)	0.5	0.6	1.6	0.1	-0.5	0.6	-1.0	-0.1	-1.3	-1.2	-0.8	-0.3	-1.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	3.1	-0.0	-0.3	-0.2	0.6	-0.7	-1.3	-0.3	-0.7	0.5	-1.8
Medication: Amlodipine	0.9	1.2	4.6	0.1	0.5	0.5	-1.7	-0.4	1.3	0.9	2.1	-0.6	1.2
Medication: Ventolin 100micrograms inhaler	0.1	0.2	1.2	0.2	-0.2	0.0	-1.1	-0.1	-0.5	0.1	-0.2	-0.1	-0.2
Birth weight	1.5	3.2	9.2	0.6	-0.6	-1.2	-1.3	-1.2	-2.6	-1.6	-1.9	2.1	-3.0
Chronic bronchitis/emphysema (mother)	1.5	1.8	5.7	-1.0	-1.4	-1.7	0.2	-0.6	-0.8	-2.4	-2.2	0.2	-0.7
High blood pressure (siblings)	0.9	1.3	5.7	0.7	0.0	0.3	1.1	0.4	0.9	0.7	2.4	-1.9	0.9
Forced vital capacity (FVC), Best measure	11.5	41.9	125.4	-1.5	-3.1	-2.2	-4.3	-3.9	-9.5	-7.2	-9.2	4.1	-11.2
Body fat percentage	0.4	1.6	4.7	1.0	1.3	1.6	-1.0	1.6	2.2	0.4	-0.2	0.5	1.3
Leg fat percentage (right)	0.2	0.9	3.1	0.9	0.9	0.8	-0.8	1.1	1.8	0.3	0.1	-0.1	1.1
Arm fat-free mass (right)	10.2	52.4	148.8	-1.4	-3.2	-2.1	-4.5	-4.8	-9.9	-7.7	-11.0	6.2	-12.2
Exposure to tobacco smoke outside home	0.6	0.8	2.6	1.0	0.8	1.4	0.0	0.6	-1.6	0.0	-0.6	-0.7	-0.6
Comparative body size at age 10	0.3	0.9	2.2	1.1	0.3	0.8	0.6	-1.3	-1.5	-0.5	0.1	-1.1	-1.3
Number of full brothers	0.6	0.7	3.5	-0.7	-1.5	-0.7	0.4	-1.9	-0.6	-0.2	0.2	-0.3	-0.3
Worry too long after embarrassment	0.7	1.1	4.3	-1.0	-0.2	-0.3	2.1	0.2	1.4	-0.2	0.3	-1.4	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.2	0.8	1.1	1.1	0.7	1.5	-0.4	-0.4	-0.9	0.4	-0.7
Wheeze or whistling in the chest in last year	0.3	0.5	1.8	0.0	0.3	0.2	0.3	0.6	1.4	-0.4	0.7	-0.9	0.8
Number of children fathered	0.9	1.0	4.0	1.1	0.3	-0.5	-0.9	-0.6	-1.4	-0.3	-1.0	-0.0	-2.0
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.8	-1.3	-0.6	-1.2	-0.2	-1.2	-0.5	-0.5	0.8	-1.4	0.3
Age at first live birth	0.9	1.6	4.6	-0.2	1.8	2.1	0.1	2.2	0.8	-1.2	0.3	0.7	0.7
Pulse wave peak to peak time	1.1	1.3	7.6	0.1	-0.7	-0.6	-2.8	-1.3	-0.8	-0.8	-0.1	-0.4	-1.4
Health satisfaction	0.7	0.9	3.9	0.4	0.3	-0.2	-0.3	1.1	-0.6	-1.1	-2.0	1.1	-0.9
Shortness of breath walking on level ground	0.2	0.3	0.8	0.9	0.4	0.1	0.1	0.6	0.1	0.7	0.4	-0.8	0.1
Qualifications: College or University degree	2.7	8.6	29.2	1.6	3.7	5.4	2.0	4.1	2.8	0.0	-0.9	2.7	1.9
Eye problems/disorders: None of the above	0.6	0.7	2.5	1.4	1.6	0.7	0.5	0.1	-0.6	1.0	-0.1	0.4	-0.7
Mouth/teeth dental problems: Loose teeth	0.2	0.3	1.1	0.6	0.2	0.2	0.3	-0.5	-1.1	-0.1	-0.1	-0.5	-0.9
Emphysema/chronic bronchitis	0.5	0.5	1.3	-0.6	-1.0	-1.1	-0.4	-0.9	-0.7	0.3	0.2	-0.4	-1.1
Medication for pain relief, constipation, heartburn	1.5	2.6	5.5	-1.9	-1.9	-1.2	0.0	-1.2	-2.3	-1.0	-1.7	1.9	-1.5
Neck or shoulder pain in last month	1.2	1.7	4.1	-1.1	-2.0	-1.9	-1.3	-1.2	-0.6	-1.1	-0.2	-1.7	-0.6
Medication: Blood pressure	1.1	1.9	3.3	0.8	1.0	1.0	-1.8	1.3	1.5	1.2	1.6	-1.8	1.4
Angina (self-reported)	0.9	1.2	4.4	0.9	0.2	-0.6	-1.6	-0.2	-1.6	-0.1	-1.0	-0.6	-2.1
Migraine (self-reported)	3.4	4.2	12.8	-0.4	0.3	0.9	2.0	0.2	2.9	1.6	2.9	-2.2	3.6
Medication: Ibuprofen	1.4	1.6	5.0	1.0	1.5	0.4	1.5	0.9	2.2	0.7	0.8	0.7	1.8
Medication: Allopurinol	0.4	0.5	1.9	0.0	-0.1	0.7	-1.4	-0.7	0.0	-0.5	0.2	-1.2	-0.4
Medication: Omeprazole	0.4	0.4	2.1	0.1	0.2	0.2	-0.4	-0.3	0.2	0.2	1.4	-1.3	-0.1
Medication: Seretide 50 evohaler	0.3	0.3	0.8	0.5	0.1	0.8	0.4	0.6	-0.7	-0.1	-0.4	-0.3	-0.9
Mean time to correctly identify matches	2.2	4.2	11.6	-3.4	-2.9	-3.3	1.7	-1.8	0.5	-0.2	1.4	-0.8	1.6
Heart disease (mother)	1.7	2.1	4.5	0.0	-1.4	-1.9	-2.1	0.6	-0.5	-1.4	-2.1	1.1	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	5.8	6.9	12.6	1.5	2.1	1.4	-1.3	2.7	3.3	2.5	3.5	-3.0	3.5
Whole body fat mass	1.0	4.3	14.9	0.5	0.2	0.8	-2.3	0.0	-1.3	-2.0	-3.9	2.7	-2.9
Leg fat mass (right)	1.0	3.7	12.2	0.4	-0.1	0.2	-2.3	-0.4	-1.6	-2.0	-3.5	2.1	-2.9
Arm predicted mass (right)	10.4	53.3	153.8	-1.3	-3.1	-1.9	-4.8	-4.7	-9.9	-7.8	-11.0	6.3	-12.4
Pulse rate, automated reading	1.1	3.6	11.9	-1.2	-0.7	0.0	0.8	2.1	3.3	0.1	1.2	-2.2	3.5
Alcohol intake frequency.	0.3	0.8	2.0	0.4	-0.2	-0.8	1.4	0.3	0.9	1.1	1.2	-0.1	1.2
Comparative height size at age 10	15.6	86.1	243.4	-0.7	-3.3	-1.8	-7.0	-4.0	-13.1	-9.7	-13.9	8.9	-15.6
Number of full sisters	0.6	0.8	2.8	1.7	-0.0	0.1	-1.5	-0.2	-0.8	1.0	0.3	-0.5	-0.8
Suffer from ‘nerves’	1.2	1.9	4.1	0.6	1.1	1.3	0.6	1.4	1.6	1.6	2.0	-1.4	1.3
Overall health rating	1.2	2.6	6.0	-0.9	-1.4	-0.9	-2.1	-0.4	-1.2	-2.2	-2.4	0.8	-2.1
Chest pain or discomfort	0.7	1.0	5.8	0.4	-0.0	-0.4	-0.2	-0.8	-1.3	-0.5	-1.1	0.1	-2.4
Had major operations	0.5	0.5	1.6	0.0	0.4	0.2	1.3	0.5	1.0	0.6	0.5	-0.0	1.3
Age at last live birth	1.4	2.1	6.8	0.7	1.8	1.6	1.5	2.6	1.5	-0.5	-0.6	1.0	1.2
Family relationship satisfaction	0.7	0.9	4.4	-0.4	-0.7	-0.0	1.3	-0.5	-0.6	-0.6	-0.6	2.1	-0.7
Leg pain on walking	0.7	0.8	2.7	0.3	-0.5	-0.7	-0.2	0.8	-0.8	-1.0	-1.6	-1.2	-0.8
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	3.5	0.0	1.4	0.1	1.9	0.9	1.2	1.1	0.9	-0.8	1.3
Commuting to job workplace: Car/motor vehicle	4.3	4.9	11.6	-3.4	-2.7	-3.4	-0.5	-3.0	-1.1	-2.2	0.1	-1.5	-1.0
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.2	-0.8	-1.0	-0.2	-0.1	-1.4	0.4	-0.1	0.4	1.5	0.0
Medication: Aspirin	0.2	0.3	1.6	0.1	-0.3	-0.5	-1.2	0.1	0.6	-0.3	-0.4	-0.6	0.3
Supplements: Vitamin C	1.3	1.6	5.7	-1.1	-1.4	-1.3	1.0	-0.5	-1.3	-2.4	-1.0	0.7	-1.0
Knee pain experienced in last month	0.6	1.0	3.2	0.4	-0.4	-1.0	-1.8	-0.8	-1.2	-0.4	-0.3	0.7	-1.6
Hypertension (Self-reported)	0.6	1.7	4.8	1.2	1.2	1.8	-2.2	1.3	1.4	0.8	1.2	-0.0	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	3.4	-1.0	-1.0	-1.3	-1.8	-0.4	0.0	-1.0	-0.7	-0.8	-1.0
Illnesses of father: Heart disease	0.3	0.4	0.8	0.4	0.4	0.6	-0.9	-0.3	-0.0	-0.8	-0.7	-0.9	-0.7
Illnesses of siblings: Diabetes	0.5	0.6	2.3	0.7	0.3	0.4	0.7	-0.8	0.7	0.8	1.0	-1.5	-0.1
Smoking status: Previous	0.5	0.8	3.6	-0.6	-0.7	-0.6	0.2	-0.8	0.7	0.4	0.4	-1.9	1.3
Forced expiratory volume in 1-second (FEV1), predicted	8.3	17.1	47.5	-0.3	-0.9	-1.0	-2.7	-1.2	-5.3	-4.0	-6.5	5.2	-6.9
Whole body fat-free mass	10.0	57.1	166.4	-1.2	-3.0	-1.7	-5.1	-4.8	-10.2	-7.8	-11.5	6.8	-12.9
Leg fat-free mass (right)	7.5	40.0	118.8	-0.3	-1.7	-0.5	-5.0	-3.5	-8.4	-6.3	-9.7	6.1	-10.9
Arm fat percentage (left)	0.7	2.9	6.3	2.0	2.1	2.3	-0.6	2.1	2.5	1.2	0.5	0.1	1.6
Average weekly red wine intake	0.1	0.2	0.8	-0.9	-0.7	-0.3	0.2	-0.4	0.1	-0.5	-0.4	0.2	-0.0
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.5	-1.0	-0.4	0.1	1.6	0.5	-0.6	0.1	-0.1	-0.8	0.5
Mood swings	1.3	2.4	6.7	0.2	0.6	-0.3	2.6	1.3	2.6	1.2	1.4	-1.3	1.8
Loneliness, isolation	0.3	0.4	1.6	0.6	0.2	-0.1	0.7	-0.2	0.2	-0.7	-1.3	0.8	-0.5
Long-standing illness, disability or infirmity	1.1	1.7	5.2	2.0	1.6	1.9	0.5	2.3	0.3	0.7	0.0	0.1	-0.0
Ever had bowel cancer screening	1.0	1.2	3.8	1.2	0.6	0.7	-1.4	1.9	-0.9	-0.2	-1.0	1.2	-0.6
Diabetes diagnosed by doctor	0.1	0.2	1.0	-0.1	0.4	-0.0	-0.6	0.9	0.2	-0.3	-1.0	0.1	0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	2.9	-1.5	-1.2	-1.7	-0.5	-0.9	-0.2	-0.6	-1.2	-0.7	0.0
Friendships satisfaction	0.9	1.1	6.3	-0.6	-0.1	0.3	0.8	1.2	1.2	-0.4	-0.1	2.5	0.5
Qualifications: nursing, teaching	0.5	0.7	1.5	1.0	0.8	0.8	0.6	0.7	-0.7	0.4	-0.9	0.9	-1.2
Commuting to job workplace: Walk	0.3	0.4	1.5	-0.2	-0.5	1.1	0.1	-0.4	1.2	-0.3	0.1	0.7	0.3
Eye problems/disorders: Cataract	1.0	1.1	3.0	-1.7	-1.5	-0.6	1.4	0.6	1.2	-0.6	-0.2	0.3	1.2
Mouth/teeth dental problems: Mouth ulcers	2.4	3.9	9.6	-2.8	-2.4	-2.9	-0.1	-3.1	0.5	-2.1	-0.7	-1.4	-0.1
Medication for cholesterol	1.2	1.8	4.3	0.8	1.0	0.6	2.1	1.0	1.3	1.9	1.3	-0.5	1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	2.0	0.3	0.3	0.0	-0.2	-0.4	-1.0	-0.6	0.2	-0.4	-1.4
Back pain experienced in last month	0.3	0.5	1.6	-0.2	-0.6	-0.6	-0.9	-1.1	-0.3	-0.1	0.7	-1.2	-0.3
Mineral and other dietary supplements	1.9	2.6	13.2	-0.1	-0.4	-0.8	-2.2	-0.4	-1.0	0.0	-1.7	3.6	-1.6
Breast cancer (self-reported)	1.1	1.3	3.9	0.5	0.4	0.5	1.7	0.4	-2.0	-0.0	-1.2	0.7	-1.8
Asthma (self-reported)	0.1	0.2	0.5	-0.3	-0.6	0.3	0.0	-0.0	-0.6	-0.5	-0.2	-0.7	-0.7
Osteoporosis (self-reported)	0.4	0.6	1.2	0.5	0.4	0.6	-0.9	0.9	-0.7	-1.1	-1.1	-0.0	-0.7
Osteoarthritis (self-reported)	0.4	0.5	1.8	-0.3	-0.4	-0.2	0.1	0.5	-0.1	-1.3	-1.1	-1.2	0.6
Medication: Aspirin	0.2	0.3	0.9	-0.2	-0.7	-0.5	-1.0	0.0	0.2	-0.4	-0.8	-0.4	0.1
Medication: Gliclazide	0.3	0.3	0.7	-0.8	-0.8	-0.5	0.6	0.6	0.4	-0.2	0.0	-0.8	0.5
Illnesses of father: None of the above (group 1)	1.4	1.7	4.3	-1.0	-1.8	-1.8	1.2	-1.0	-2.1	-0.9	-0.6	-0.5	-0.9
Smoking status: Current	0.8	1.2	3.4	-0.4	-0.4	0.8	1.8	0.6	1.0	0.5	1.8	-1.4	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.3	9.3	-0.0	-0.7	-1.2	-1.9	-1.7	-3.1	-1.7	-2.1	0.9	-2.7
Whole body water mass	10.1	57.9	169.0	-1.3	-3.0	-1.7	-5.2	-4.8	-10.3	-7.9	-11.5	6.7	-13.0
Leg predicted mass (right)	7.4	39.4	116.6	-0.2	-1.7	-0.5	-4.9	-3.5	-8.3	-6.3	-9.6	6.1	-10.8
Arm fat mass (left)	1.0	3.9	12.5	1.4	0.9	1.4	-1.9	0.3	-1.4	-1.6	-3.5	2.3	-3.0
Number of self-reported non-cancer illnesses	0.4	0.7	2.2	0.7	1.1	1.5	-0.3	1.0	0.8	-0.5	0.1	-1.2	-0.4
Average weekly champagne plus white wine intake	1.2	1.6	5.0	-0.5	0.2	0.5	-0.1	-1.7	-1.9	-1.3	-1.5	0.5	-2.2
Miserableness	0.4	0.7	2.5	1.0	0.8	1.6	1.3	0.9	0.1	0.1	-0.1	0.4	-0.6
Guilty feelings	0.5	0.8	1.7	-0.7	-0.2	0.3	1.2	-1.2	-0.7	-1.2	-0.6	0.7	-1.3
Wears glasses or contact lenses	1.2	1.4	3.3	1.8	1.5	0.8	-0.3	0.7	0.3	1.7	1.4	-1.4	0.6
Ever taken oral contraceptive pill	1.2	1.3	3.6	-1.6	-1.9	-1.4	-0.3	-1.9	0.9	-0.2	0.7	-0.2	0.7
Hearing aid user	0.7	0.8	1.8	-0.3	-0.1	-0.9	1.1	1.4	1.1	-0.5	0.4	1.0	1.1
Mother’s age at death	0.9	1.1	2.7	-1.6	-1.6	-1.5	0.5	-0.8	0.4	-1.3	-0.7	-0.7	0.5
Financial situation satisfaction	0.4	0.4	0.9	-0.3	0.0	-0.7	0.8	0.7	0.9	-0.4	-1.0	0.8	0.0
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.2	-0.1	0.1	0.1	-0.3	1.1	0.3	-0.2	0.2	0.1	0.6
Commuting to job workplace: Public transport	5.7	6.8	14.1	3.6	3.0	3.8	1.1	3.7	2.4	2.7	0.7	0.9	1.6
Eye problems/disorders: Glaucoma	0.4	0.5	3.5	0.1	0.5	-0.0	-1.9	-0.2	0.1	-0.8	-0.3	-0.3	-0.1
Medication: Blood pressure	0.4	0.7	3.7	0.7	0.0	0.6	-1.9	0.1	-0.5	-0.8	-0.4	0.6	-1.1
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.2	0.5	1.1	0.4	1.3	0.6	1.8	0.3	0.6	-0.8	1.6
Supplements: Fish oil (including cod liver oil)	2.5	3.3	12.0	-0.1	0.2	0.1	2.5	0.6	1.8	0.3	2.1	-3.5	2.5
High cholesterol (Self-reported)	1.3	2.2	5.8	-2.4	-2.0	-1.9	-1.1	-1.1	0.0	-2.2	-1.2	-0.6	0.2
Medication: Bendroflumethiazide	1.3	2.0	5.7	1.5	2.1	2.4	1.4	1.9	1.1	0.2	0.4	0.7	0.5
Medication: Paracetamol	1.1	1.8	6.5	-0.1	0.1	0.3	-0.4	0.2	1.9	0.5	2.1	-2.5	1.6
Medication: Lisinopril	0.5	0.6	3.3	0.2	0.1	0.2	-0.7	-0.1	1.4	0.2	0.6	-1.8	0.2
Medication: Atorvastatin	1.1	1.4	4.5	-1.0	-1.5	-1.2	-2.1	-1.4	-0.3	-0.5	-0.3	-1.4	-0.9
Illnesses of father: High blood pressure	2.1	2.7	5.5	1.8	1.9	1.3	1.3	1.4	2.4	1.8	1.6	0.7	1.6
Alcohol drinker status: Never	0.6	0.7	2.1	0.4	0.6	-0.7	0.0	0.7	0.5	1.0	1.2	-0.9	1.4
Ever smoked	1.0	1.7	3.2	-1.8	-1.7	-1.0	1.6	-1.4	0.9	-0.1	-0.1	-1.7	1.3
Basal metabolic rate	8.9	49.5	146.4	-0.8	-2.4	-1.1	-5.0	-4.1	-9.3	-7.2	-10.9	6.5	-12.1
Leg fat percentage (left)	0.2	0.8	2.6	1.1	1.1	0.9	-0.7	0.9	1.6	0.2	-0.0	-0.4	0.9
Arm fat-free mass (left)	10.4	52.8	156.2	-1.2	-3.0	-1.9	-4.8	-4.7	-10.0	-7.7	-10.9	5.8	-12.5
Number of operations (self-reported)	0.4	0.6	2.1	0.7	0.6	-0.3	0.6	0.7	-0.6	-0.0	-1.5	1.1	-0.6
Average weekly beer plus cider intake	0.8	1.1	4.2	0.8	0.1	0.7	0.5	-1.0	-1.8	-0.6	-0.6	-0.9	-2.1
Irritability	0.9	1.6	3.2	1.7	1.8	1.3	0.5	0.4	-0.4	0.8	1.6	-1.7	-1.2
Risk taking	2.2	3.2	6.8	-1.9	-2.6	-1.8	0.9	-0.8	-1.5	-2.5	-1.7	1.9	-1.5
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.2	-1.2	-0.8	-0.3	0.8	0.1	0.2	-1.5	-0.7	-0.3	-0.4
Fractured/broken bones in last 5 years	0.7	0.9	2.2	1.5	0.9	0.7	-1.0	0.8	-0.6	0.0	-1.0	1.0	-1.3
Age started oral contraceptive pill	0.6	0.8	2.0	-0.3	0.9	1.2	0.7	0.9	1.4	0.2	0.8	-0.3	1.3
Diastolic blood pressure, automated reading	4.7	14.4	27.2	2.7	3.0	3.5	1.6	2.6	4.9	5.2	5.0	-2.6	4.9
Ever depressed for a whole week	1.5	1.9	6.2	0.8	-0.1	-0.0	0.3	1.1	-1.5	-1.7	-2.3	0.4	-2.5
Unable to work because of sickness or disability	1.0	1.3	4.0	0.1	-0.8	-1.6	-1.1	-0.2	-1.4	-0.4	-2.0	-0.0	-1.6
Commuting to job workplace: Cycle	0.3	0.4	1.7	0.4	0.9	1.3	0.2	0.5	-0.1	0.0	0.1	0.9	0.0
Myopia	0.6	0.9	3.8	-0.5	0.3	-0.1	-0.4	0.0	-0.8	-2.0	-1.6	1.1	-0.5
Vascular/heart problems diagnosed by doctor	0.6	1.5	3.5	-1.5	-1.5	-1.9	1.9	-1.4	-0.9	-0.7	-0.7	-0.3	-0.1
Cholesterol lowering medication	1.4	2.1	5.1	-1.5	-1.7	-1.4	-0.6	-1.9	-1.1	-2.3	-1.1	0.1	-1.4
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.4	0.3	0.9	0.1	-0.8	0.3	0.9	0.5	1.6	-1.1	0.2
Pain experienced in last month	1.3	2.1	7.5	0.9	1.4	1.6	-0.4	2.4	-0.3	0.1	-1.4	2.7	-0.1
Supplements: Calcium	0.2	0.2	0.6	0.0	0.6	0.2	0.4	-0.3	0.2	0.0	0.8	0.6	0.7
Basal cell carcinoma (self-reported)	0.8	1.0	2.4	0.8	1.1	-0.2	1.4	0.7	0.8	1.2	1.5	0.1	0.8
Heart attack/myocardial infarction (self-reported)	1.2	1.5	5.4	0.8	-0.2	0.2	-1.0	-0.1	-2.2	-0.8	-1.4	-0.9	-2.3
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	4.5	-0.7	-0.8	-0.9	-1.1	-0.3	-1.7	-1.4	-2.1	1.2	-1.9
Heart disease (siblings)	0.3	0.4	1.0	0.3	-0.6	-0.2	0.1	0.4	-0.5	-1.0	-1.0	-0.3	-0.9
Alcohol drinker status: Previous	1.1	1.3	4.4	-0.6	-0.7	-0.9	-0.1	-1.8	0.4	0.8	1.5	-2.1	0.8
Pack years of smoking	0.7	1.0	2.3	-0.7	-1.1	-1.0	1.3	-0.5	0.6	1.1	1.2	-0.2	1.5
Impedance of whole body	2.1	10.9	30.7	0.8	1.9	1.9	2.6	3.2	5.0	3.2	4.0	-1.7	5.5
Leg fat mass (left)	1.0	4.0	13.5	0.6	0.0	0.4	-2.2	-0.4	-1.7	-2.1	-3.7	2.0	-3.0
Arm predicted mass (left)	10.3	52.2	153.8	-1.2	-3.0	-1.8	-4.8	-4.7	-9.9	-7.6	-11.0	5.7	-12.4