TWAS hub - SCMH1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0930	0.0290	1.9e-04	0.085	NA	0.080	NA	0.077	1.8e-07	NA	4.0e-07	NA	6.7e-07
2	GTEx	Artery Aorta	0.2690	0.0670	1.8e-06	0.114	NA	0.074	NA	0.102	7.4e-07	NA	7.0e-05	NA	3.0e-06
3	GTEx	Artery Tibial	0.0854	0.0312	1.7e-03	0.008	NA	-0.001	NA	0.004	7.3e-02	NA	3.8e-01	NA	1.4e-01
4	GTEx	Colon Transverse	0.1620	0.0700	9.9e-03	0.066	NA	0.055	NA	0.041	4.7e-04	NA	1.2e-03	NA	5.0e-03
5	GTEx	Esophagus Muscularis	0.1760	0.0480	1.1e-05	0.025	NA	0.101	NA	0.052	1.1e-02	NA	1.1e-06	NA	4.0e-04
6	GTEx	Nerve Tibial	0.1555	0.0428	6.5e-06	0.033	NA	0.068	NA	0.037	2.0e-03	NA	1.6e-05	NA	1.1e-03
7	TCGA	Brain Lower Grade Glioma	0.0406	0.0245	3.0e-03	0.013	0.011	0.019	NA	0.012	1.1e-02	1.7e-02	2.5e-03	NA	1.5e-02
8	TCGA	Prostate Adenocarcinoma	0.0310	0.0199	7.1e-03	0.026	0.015	0.004	NA	0.017	8.4e-04	8.4e-03	1.1e-01	NA	6.2e-03
9	TCGA	Testicular Germ Cell Tumors	0.3460	0.1250	2.2e-04	0.138	0.137	0.116	NA	0.108	1.4e-05	1.5e-05	7.0e-05	NA	1.3e-04
10	TCGA	Thyroid Carcinoma	0.0710	0.0300	5.0e-07	0.076	0.070	0.059	NA	0.063	7.0e-08	2.5e-07	2.2e-06	NA	1.0e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Comparative height size at age 10	15.6	86.1	243.4	-0.7	-3.3	-1.8	-7.0	-4.0	-13.1	-9.7	-13.9	8.9	-15.6
Trunk fat-free mass	11.6	66.6	196.0	-1.6	-3.6	-2.3	-5.0	-5.5	-11.2	-8.4	-12.2	7.0	-14.0
Trunk predicted mass	11.6	66.3	196.0	-1.6	-3.6	-2.4	-4.9	-5.6	-11.2	-8.3	-12.2	6.9	-14.0
Forced vital capacity (FVC), Best measure	11.5	41.9	125.4	-1.5	-3.1	-2.2	-4.3	-3.9	-9.5	-7.2	-9.2	4.1	-11.2
Arm predicted mass (right)	10.4	53.3	153.8	-1.3	-3.1	-1.9	-4.8	-4.7	-9.9	-7.8	-11.0	6.3	-12.4
Arm fat-free mass (left)	10.4	52.8	156.2	-1.2	-3.0	-1.9	-4.8	-4.7	-10.0	-7.7	-10.9	5.8	-12.5
Forced vital capacity (FVC)	10.3	39.8	127.7	-0.9	-2.6	-1.9	-3.5	-3.8	-9.6	-6.3	-9.3	3.9	-11.3
Arm predicted mass (left)	10.3	52.2	153.8	-1.2	-3.0	-1.8	-4.8	-4.7	-9.9	-7.6	-11.0	5.7	-12.4
Standing height	10.2	100.9	282.2	-2.2	-3.8	-2.0	-6.1	-5.4	-13.3	-10.3	-15.7	10.4	-16.8
Arm fat-free mass (right)	10.2	52.4	148.8	-1.4	-3.2	-2.1	-4.5	-4.8	-9.9	-7.7	-11.0	6.2	-12.2
Whole body water mass	10.1	57.9	169.0	-1.3	-3.0	-1.7	-5.2	-4.8	-10.3	-7.9	-11.5	6.7	-13.0
Whole body fat-free mass	10.0	57.1	166.4	-1.2	-3.0	-1.7	-5.1	-4.8	-10.2	-7.8	-11.5	6.8	-12.9
Height	9.7	187.2	484.0	-4.5	-6.6	-4.5	-8.6	-7.6	-17.2	-15.5	-22.0	13.5	-21.3
Sitting height	9.3	65.8	201.6	0.0	-2.3	-0.7	-5.4	-4.8	-11.5	-6.5	-11.8	9.2	-14.2
Basal metabolic rate	8.9	49.5	146.4	-0.8	-2.4	-1.1	-5.0	-4.1	-9.3	-7.2	-10.9	6.5	-12.1
Forced expiratory volume in 1-second (FEV1), Best measure	8.5	27.1	79.4	-0.9	-2.0	-1.5	-3.5	-3.3	-7.8	-5.9	-7.3	3.3	-8.9
Forced expiratory volume in 1-second (FEV1), predicted	8.3	17.1	47.5	-0.3	-0.9	-1.0	-2.7	-1.2	-5.3	-4.0	-6.5	5.2	-6.9
Leg fat-free mass (right)	7.5	40.0	118.8	-0.3	-1.7	-0.5	-5.0	-3.5	-8.4	-6.3	-9.7	6.1	-10.9
Leg predicted mass (right)	7.4	39.4	116.6	-0.2	-1.7	-0.5	-4.9	-3.5	-8.3	-6.3	-9.6	6.1	-10.8
Leg fat-free mass (left)	7.3	38.7	112.4	-0.3	-1.6	-0.3	-4.9	-3.1	-8.2	-6.2	-9.7	6.3	-10.6
Leg predicted mass (left)	7.2	38.3	110.2	-0.3	-1.7	-0.4	-4.9	-3.2	-8.2	-6.1	-9.7	6.2	-10.5
Forced expiratory volume in 1-second (FEV1)	7.2	24.4	75.1	-0.6	-1.8	-1.2	-2.7	-3.3	-7.7	-5.2	-7.1	3.0	-8.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	5.8	6.9	12.6	1.5	2.1	1.4	-1.3	2.7	3.3	2.5	3.5	-3.0	3.5
Commuting to job workplace: Public transport	5.7	6.8	14.1	3.6	3.0	3.8	1.1	3.7	2.4	2.7	0.7	0.9	1.6
Hand grip strength (right)	5.4	14.5	40.6	-2.8	-3.2	-1.7	-1.3	-2.4	-4.6	-4.8	-6.4	2.8	-4.9
Relative age voice broke	5.2	7.9	25.4	-0.3	1.5	1.5	1.9	2.5	4.9	1.9	3.0	-1.7	5.0
Verbal and Numeric Reasoning (VNR)	5.1	12.2	37.4	2.8	3.5	5.1	1.2	6.1	3.9	1.8	0.3	2.3	3.7
Weight	5.0	24.4	68.5	0.2	-0.9	-0.1	-4.3	-2.2	-6.0	-4.8	-8.1	5.2	-8.3
Diastolic blood pressure, automated reading	4.7	14.4	27.2	2.7	3.0	3.5	1.6	2.6	4.9	5.2	5.0	-2.6	4.9
Commuting to job workplace: Car/motor vehicle	4.3	4.9	11.6	-3.4	-2.7	-3.4	-0.5	-3.0	-1.1	-2.2	0.1	-1.5	-1.0
Intelligence (Savage-Jansen 2018)	4.1	12.6	34.8	2.7	3.6	5.9	-0.7	5.4	4.3	2.1	0.9	2.3	3.5
Heel T-Score	3.7	29.6	94.5	-0.5	-0.3	0.5	2.1	0.0	6.7	5.3	9.7	-7.2	8.4
Systolic Blood Pressure	3.7	18.3	34.2	4.5	4.7	5.3	1.4	3.6	3.7	5.8	5.3	-2.0	4.1
Systolic blood pressure, automated reading	3.4	9.8	19.1	3.4	3.3	3.5	0.5	2.7	3.0	4.4	3.9	-1.2	3.4
Migraine (self-reported)	3.4	4.2	12.8	-0.4	0.3	0.9	2.0	0.2	2.9	1.6	2.9	-2.2	3.6
Alzheimer’s Disease (in father)	3.3	3.6	7.3	1.4	1.8	2.1	1.2	1.3	2.1	1.4	2.3	-2.7	2.2
Hand grip strength (left)	3.0	7.9	22.4	-2.0	-2.2	-0.4	-0.9	-1.5	-3.7	-3.5	-4.7	2.1	-3.8
Impedance of arm (left)	3.0	14.0	33.6	1.6	3.0	3.0	2.4	3.9	5.5	3.8	4.3	-0.9	5.8
Fluid intelligence score	2.9	6.0	16.4	1.3	2.3	4.0	1.5	3.7	3.3	0.7	-0.5	1.4	2.6
Ever used hormone-replacement therapy (HRT)	2.8	3.5	12.0	-2.0	-1.6	-0.2	-0.6	-1.2	-1.7	-3.5	-2.7	-0.8	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	2.7	6.2	21.2	-1.9	-0.9	0.0	-0.6	-2.5	2.7	1.1	4.6	-3.8	2.5
Qualifications: A levels/AS levels or equivalent	2.7	6.0	12.9	1.5	2.9	3.5	2.2	3.6	2.3	0.1	0.2	3.1	2.0
Hair/balding pattern: Pattern 4	2.7	6.6	22.2	-2.3	-0.9	-1.8	1.1	-1.8	-0.5	-3.2	-4.0	4.7	-1.9
Qualifications: College or University degree	2.7	8.6	29.2	1.6	3.7	5.4	2.0	4.1	2.8	0.0	-0.9	2.7	1.9
Relative age of first facial hair	2.6	5.4	17.3	-0.7	0.6	1.0	3.3	2.1	3.5	0.7	2.3	-1.4	4.2
Impedance of arm (right)	2.6	12.3	30.8	1.3	2.6	2.6	1.9	3.6	5.1	3.7	4.4	-1.2	5.5
Type 2 Diabetes (T2D) (2012)	2.5	2.9	7.5	-1.0	-1.0	-0.3	1.3	-1.0	2.0	1.0	2.7	-2.5	2.3
Supplements: Fish oil (including cod liver oil)	2.5	3.3	12.0	-0.1	0.2	0.1	2.5	0.6	1.8	0.3	2.1	-3.5	2.5
Eye problems/disorders: Diabetes related eye disease	2.4	2.6	7.0	-0.4	-2.1	-2.6	-0.5	-0.1	-1.7	-1.9	-2.1	1.0	-1.4
Heel bone mineral density (BMD) T-score, automated (left)	2.4	5.5	17.7	-1.7	-0.9	0.1	-0.2	-1.9	2.9	1.1	4.2	-3.5	2.8
Mouth/teeth dental problems: Mouth ulcers	2.4	3.9	9.6	-2.8	-2.4	-2.9	-0.1	-3.1	0.5	-2.1	-0.7	-1.4	-0.1
Lung FVC	2.3	11.9	32.5	-1.6	-2.4	-2.1	-2.6	-3.8	-5.7	-3.4	-3.2	0.7	-5.5
Age when periods started (menarche)	2.3	5.4	18.7	-0.1	1.5	0.9	2.1	2.4	4.0	1.8	1.6	-0.4	4.3
Qualifications: None of the above	2.2	4.8	9.1	-0.8	-2.6	-2.6	-2.3	-3.0	-3.0	-1.5	-1.0	-0.6	-2.6
Mean time to correctly identify matches	2.2	4.2	11.6	-3.4	-2.9	-3.3	1.7	-1.8	0.5	-0.2	1.4	-0.8	1.6
Risk taking	2.2	3.2	6.8	-1.9	-2.6	-1.8	0.9	-0.8	-1.5	-2.5	-1.7	1.9	-1.5
Body Mass Index (BMI) (2010)	2.1	2.9	6.5	-1.9	-2.1	-1.1	-1.4	-2.0	-1.1	-2.5	-1.7	-0.4	-1.7
Peak expiratory flow (PEF)	2.1	5.0	14.1	0.5	0.4	1.6	-1.0	-0.3	-2.9	-2.4	-3.5	2.4	-3.8
Illnesses of father: High blood pressure	2.1	2.7	5.5	1.8	1.9	1.3	1.3	1.4	2.4	1.8	1.6	0.7	1.6
Impedance of whole body	2.1	10.9	30.7	0.8	1.9	1.9	2.6	3.2	5.0	3.2	4.0	-1.7	5.5
Alzheimer’s Disease (including proxy)	2.0	2.9	7.3	1.2	2.6	2.7	1.3	1.8	1.5	0.3	1.0	-1.9	1.3
Lupus	2.0	3.1	8.5	2.2	2.5	2.9	1.4	1.7	0.6	1.6	1.6	-0.7	0.7
Hip circumference	2.0	8.7	24.1	1.9	1.0	1.4	-3.1	-0.4	-2.7	-1.8	-4.8	3.5	-4.9
Medication: Lansoprazole	2.0	2.3	6.1	-0.1	0.2	-0.6	-2.4	0.5	-0.7	-2.4	-2.5	-0.1	-2.0
Primary Biliary Cirrhosis	1.9	2.6	6.1	-1.8	-2.2	-1.4	-1.3	-2.5	-0.8	-2.0	-1.2	-0.9	-1.2
Blood White Count	1.9	13.9	24.1	2.9	4.3	4.0	2.2	4.0	4.9	3.9	3.7	-0.0	4.6
Tinnitus: Yes, but not now, but have in the past	1.9	2.1	10.8	-0.6	-0.4	0.2	0.7	0.8	3.3	0.4	1.3	-1.0	2.3
Blood clot in the leg (DVT)	1.9	2.4	5.8	-0.9	-1.1	-1.1	-1.0	-0.6	-2.0	-1.7	-2.4	1.3	-2.3
Mineral and other dietary supplements	1.9	2.6	13.2	-0.1	-0.4	-0.8	-2.2	-0.4	-1.0	0.0	-1.7	3.6	-1.6
Reaction Time	1.8	3.5	7.8	-2.8	-2.3	-2.7	2.0	-1.6	0.7	0.5	1.7	-1.3	1.6
Sensitivity / hurt feelings	1.8	3.1	9.6	-2.2	-2.3	-3.1	1.1	-2.8	0.2	-0.6	0.9	-0.8	-0.1
Qualifications: CSEs or equivalent	1.8	2.4	12.7	0.2	0.1	-0.7	0.0	-1.4	-0.0	1.6	2.5	-3.6	0.0
Diverticular disease/diverticulitis (self-reported)	1.8	2.1	4.3	1.7	1.7	2.1	-2.1	1.9	-0.4	0.2	-1.1	1.3	-0.5
Birth weight of first child	1.8	3.3	10.8	-0.7	-1.7	-1.5	-0.1	-1.8	-3.3	-0.9	-2.5	0.2	-2.6
Schizophrenia (2014)	1.7	3.8	10.9	-0.1	-0.5	0.3	-1.0	-0.5	-3.0	-2.6	-2.0	2.4	-3.3
Heart disease (mother)	1.7	2.1	4.5	0.0	-1.4	-1.9	-2.1	0.6	-0.5	-1.4	-2.1	1.1	-1.6
Bipolar Disorder or Schizophrenia	1.6	3.8	14.0	0.2	0.3	0.4	-0.3	-0.8	-3.0	-2.0	-1.7	2.7	-3.7
Hair/balding pattern: Pattern 3	1.6	2.4	4.7	-0.8	-2.0	-1.6	0.9	-1.1	-2.0	-1.8	-1.8	0.1	-2.2
Tense / ‘highly strung’	1.6	2.7	6.6	1.6	2.6	1.4	1.6	2.0	1.8	2.1	1.1	-0.1	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.3	9.3	-0.0	-0.7	-1.2	-1.9	-1.7	-3.1	-1.7	-2.1	0.9	-2.7
Bipolar Disorder (2011)	1.5	1.5	6.2	-0.3	0.1	-0.6	-0.1	-1.3	-1.6	-1.0	-1.4	0.8	-2.5
Waist circumference	1.5	5.5	14.0	1.6	1.1	1.6	-2.0	0.3	-2.2	-1.9	-3.7	2.9	-3.7
Medication: Paracetamol	1.5	2.5	6.3	0.5	0.8	1.2	0.6	1.1	2.5	0.7	2.3	-2.2	2.1
Birth weight	1.5	3.2	9.2	0.6	-0.6	-1.2	-1.3	-1.2	-2.6	-1.6	-1.9	2.1	-3.0
Chronic bronchitis/emphysema (mother)	1.5	1.8	5.7	-1.0	-1.4	-1.7	0.2	-0.6	-0.8	-2.4	-2.2	0.2	-0.7
Medication for pain relief, constipation, heartburn	1.5	2.6	5.5	-1.9	-1.9	-1.2	0.0	-1.2	-2.3	-1.0	-1.7	1.9	-1.5
Ever depressed for a whole week	1.5	1.9	6.2	0.8	-0.1	-0.0	0.3	1.1	-1.5	-1.7	-2.3	0.4	-2.5
Alzheimer’s Disease (in mother)	1.4	1.6	6.0	0.6	2.4	2.4	-0.1	1.7	0.6	-0.5	-0.5	-1.0	0.1
Ovarian Cancer	1.4	1.9	6.7	-2.6	-2.0	-1.6	0.9	-1.9	0.4	-1.0	0.2	0.1	0.4
Blood Platelet Count	1.4	16.6	50.7	-0.4	2.2	2.0	2.4	1.0	7.1	3.5	6.0	-0.9	7.1
Headache pain in last month	1.4	2.3	8.0	-0.5	-0.8	-0.9	1.4	-0.1	2.8	0.2	1.8	-1.4	2.5
Medication: Ibuprofen	1.4	1.6	5.0	1.0	1.5	0.4	1.5	0.9	2.2	0.7	0.8	0.7	1.8
Age at last live birth	1.4	2.1	6.8	0.7	1.8	1.6	1.5	2.6	1.5	-0.5	-0.6	1.0	1.2
Illnesses of father: None of the above (group 1)	1.4	1.7	4.3	-1.0	-1.8	-1.8	1.2	-1.0	-2.1	-0.9	-0.6	-0.5	-0.9
Cholesterol lowering medication	1.4	2.1	5.1	-1.5	-1.7	-1.4	-0.6	-1.9	-1.1	-2.3	-1.1	0.1	-1.4
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	4.5	-0.7	-0.8	-0.9	-1.1	-0.3	-1.7	-1.4	-2.1	1.2	-1.9
Bipolar Disorder (2018)	1.3	2.0	7.1	1.0	1.2	0.6	0.2	-0.7	-1.6	-0.7	-0.8	2.5	-2.7
Breast Cancer	1.3	3.2	6.4	-2.5	-2.3	-2.4	-1.8	-1.9	-0.2	-2.2	-1.4	-0.4	-1.0
Number of treatments/medications taken	1.3	2.3	7.7	0.9	0.9	1.1	0.1	1.3	2.2	0.9	1.6	-2.8	1.6
Current tobacco smoking	1.3	2.2	5.6	-0.1	-0.1	1.1	2.4	1.1	1.5	0.9	2.3	-1.7	1.6
Alcohol usually taken with meals	1.3	2.1	7.2	-1.2	-0.9	-1.0	-0.2	0.5	-0.2	-1.5	-2.5	2.7	-1.5
Qualifications: O levels/GCSEs or equivalent	1.3	2.1	5.7	1.3	2.0	1.5	0.6	2.4	1.2	1.2	0.2	1.7	0.8
Supplements: Vitamin C	1.3	1.6	5.7	-1.1	-1.4	-1.3	1.0	-0.5	-1.3	-2.4	-1.0	0.7	-1.0
Mood swings	1.3	2.4	6.7	0.2	0.6	-0.3	2.6	1.3	2.6	1.2	1.4	-1.3	1.8
High cholesterol (Self-reported)	1.3	2.2	5.8	-2.4	-2.0	-1.9	-1.1	-1.1	0.0	-2.2	-1.2	-0.6	0.2
Medication: Bendroflumethiazide	1.3	2.0	5.7	1.5	2.1	2.4	1.4	1.9	1.1	0.2	0.4	0.7	0.5
Pain experienced in last month	1.3	2.1	7.5	0.9	1.4	1.6	-0.4	2.4	-0.3	0.1	-1.4	2.7	-0.1
Coronary Artery Disease (CAD)	1.2	1.4	5.8	-0.5	-1.0	-0.6	-1.4	-0.7	0.4	1.4	1.1	-2.4	0.8
Ever had hysterectomy (womb removed)	1.2	1.4	2.6	-0.1	-0.9	-1.3	-1.2	-1.4	-1.6	-1.2	-0.7	-0.6	-1.6
Medication for hormone replacement therapy	1.2	1.3	2.6	-0.9	-0.4	-1.1	-1.3	-0.3	-1.6	-1.2	-1.5	1.0	-1.3
Severe depression (siblings)	1.2	1.3	4.7	1.3	1.2	1.5	1.0	0.8	0.7	0.0	1.0	-2.2	0.4
Impedance of leg (right)	1.2	5.7	17.3	-0.3	0.6	0.4	2.9	1.9	3.6	1.8	2.8	-1.6	4.2
Heart attack	1.2	1.5	5.3	0.7	-0.4	0.1	-1.2	-0.4	-2.2	-0.8	-1.2	-0.9	-2.3
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	4.4	1.2	1.4	0.4	1.6	0.4	2.1	0.9	0.8	0.7	1.6
Neck or shoulder pain in last month	1.2	1.7	4.1	-1.1	-2.0	-1.9	-1.3	-1.2	-0.6	-1.1	-0.2	-1.7	-0.6
Suffer from ‘nerves’	1.2	1.9	4.1	0.6	1.1	1.3	0.6	1.4	1.6	1.6	2.0	-1.4	1.3
Overall health rating	1.2	2.6	6.0	-0.9	-1.4	-0.9	-2.1	-0.4	-1.2	-2.2	-2.4	0.8	-2.1
Medication for cholesterol	1.2	1.8	4.3	0.8	1.0	0.6	2.1	1.0	1.3	1.9	1.3	-0.5	1.9
Average weekly champagne plus white wine intake	1.2	1.6	5.0	-0.5	0.2	0.5	-0.1	-1.7	-1.9	-1.3	-1.5	0.5	-2.2
Wears glasses or contact lenses	1.2	1.4	3.3	1.8	1.5	0.8	-0.3	0.7	0.3	1.7	1.4	-1.4	0.6
Ever taken oral contraceptive pill	1.2	1.3	3.6	-1.6	-1.9	-1.4	-0.3	-1.9	0.9	-0.2	0.7	-0.2	0.7
Heart attack/myocardial infarction (self-reported)	1.2	1.5	5.4	0.8	-0.2	0.2	-1.0	-0.1	-2.2	-0.8	-1.4	-0.9	-2.3
Schizophrenia (2018)	1.1	2.4	7.1	-0.5	-0.6	0.1	-0.5	-0.5	-2.5	-2.0	-1.6	1.5	-2.7
Neuroticism (2016)	1.1	1.6	4.3	-0.5	0.3	-0.2	2.1	0.8	2.1	-0.1	1.7	-0.7	1.7
Ulcerative Colitis	1.1	1.7	5.4	-1.5	-1.3	-1.8	-1.7	-2.3	-0.4	0.1	0.6	-0.3	-0.6
Chronotype (morning person)	1.1	2.6	7.5	-0.3	0.1	-1.1	0.6	-1.3	1.5	1.0	2.7	-2.7	2.1
Supplements: Zinc	1.1	1.2	3.6	-1.2	-1.2	0.9	1.4	0.4	-0.9	-1.9	-1.2	-0.8	-0.5
Impedance of leg (left)	1.1	5.4	15.5	-0.4	0.4	0.0	3.1	1.6	3.5	1.5	2.7	-2.0	3.9
Trunk fat mass	1.1	4.7	16.7	0.4	0.2	0.9	-2.3	0.0	-1.4	-2.2	-4.1	2.9	-3.0
Mouth/teeth dental problems	1.1	1.7	4.9	-0.6	0.5	1.0	0.0	1.0	2.2	1.6	1.6	0.4	2.0
Alcohol intake versus 10 years previously	1.1	1.6	6.2	-0.7	-2.3	-2.5	-0.1	-0.6	0.2	0.3	-0.2	2.0	0.2
Mouth/teeth dental problems: Bleeding gums	1.1	1.5	4.3	1.1	0.4	0.5	0.4	0.5	-1.4	-2.0	-2.1	0.8	-1.4
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	6.0	-0.2	-0.5	-0.5	2.5	-0.9	-1.8	-0.7	-1.2	2.0	-1.5
Pulse wave peak to peak time	1.1	1.3	7.6	0.1	-0.7	-0.6	-2.8	-1.3	-0.8	-0.8	-0.1	-0.4	-1.4
Medication: Blood pressure	1.1	1.9	3.3	0.8	1.0	1.0	-1.8	1.3	1.5	1.2	1.6	-1.8	1.4
Pulse rate, automated reading	1.1	3.6	11.9	-1.2	-0.7	0.0	0.8	2.1	3.3	0.1	1.2	-2.2	3.5
Long-standing illness, disability or infirmity	1.1	1.7	5.2	2.0	1.6	1.9	0.5	2.3	0.3	0.7	0.0	0.1	-0.0
Breast cancer (self-reported)	1.1	1.3	3.9	0.5	0.4	0.5	1.7	0.4	-2.0	-0.0	-1.2	0.7	-1.8
Medication: Paracetamol	1.1	1.8	6.5	-0.1	0.1	0.3	-0.4	0.2	1.9	0.5	2.1	-2.5	1.6
Medication: Atorvastatin	1.1	1.4	4.5	-1.0	-1.5	-1.2	-2.1	-1.4	-0.3	-0.5	-0.3	-1.4	-0.9
Alcohol drinker status: Previous	1.1	1.3	4.4	-0.6	-0.7	-0.9	-0.1	-1.8	0.4	0.8	1.5	-2.1	0.8
Smoking Status	1.0	2.5	7.6	-1.3	-1.3	0.2	1.2	-0.3	1.8	0.4	2.0	-2.8	2.3
Cardiovascular Disease	1.0	3.3	7.0	2.4	2.3	2.6	-2.3	1.9	1.2	1.3	1.4	0.9	0.1
Noisy workplace	1.0	1.2	3.6	1.4	0.9	0.8	-1.5	0.7	-0.0	1.2	0.7	-1.9	0.0
Length of working week for main job	1.0	1.1	2.8	0.8	1.0	0.3	-0.1	0.8	-1.2	0.3	-1.6	-1.2	-1.7
Exposure to tobacco smoke at home	1.0	1.1	1.9	-1.3	-1.3	-0.6	-1.2	-1.4	-1.3	-0.9	-0.4	-1.0	-0.4
Pulse wave reflection index	1.0	1.2	8.8	-0.5	-0.0	-0.8	3.0	-0.4	0.6	0.7	0.3	0.4	0.9
Whole body fat mass	1.0	4.3	14.9	0.5	0.2	0.8	-2.3	0.0	-1.3	-2.0	-3.9	2.7	-2.9
Leg fat mass (right)	1.0	3.7	12.2	0.4	-0.1	0.2	-2.3	-0.4	-1.6	-2.0	-3.5	2.1	-2.9
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	3.5	0.0	1.4	0.1	1.9	0.9	1.2	1.1	0.9	-0.8	1.3
Ever had bowel cancer screening	1.0	1.2	3.8	1.2	0.6	0.7	-1.4	1.9	-0.9	-0.2	-1.0	1.2	-0.6
Eye problems/disorders: Cataract	1.0	1.1	3.0	-1.7	-1.5	-0.6	1.4	0.6	1.2	-0.6	-0.2	0.3	1.2
Arm fat mass (left)	1.0	3.9	12.5	1.4	0.9	1.4	-1.9	0.3	-1.4	-1.6	-3.5	2.3	-3.0
Ever smoked	1.0	1.7	3.2	-1.8	-1.7	-1.0	1.6	-1.4	0.9	-0.1	-0.1	-1.7	1.3
Unable to work because of sickness or disability	1.0	1.3	4.0	0.1	-0.8	-1.6	-1.1	-0.2	-1.4	-0.4	-2.0	-0.0	-1.6
Leg fat mass (left)	1.0	4.0	13.5	0.6	0.0	0.4	-2.2	-0.4	-1.7	-2.1	-3.7	2.0	-3.0
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	3.0	1.0	0.6	0.9	-0.4	0.8	-1.3	-0.9	-1.7	0.4	-1.7
Angina	0.9	1.2	4.1	0.8	0.1	-0.6	-1.7	-0.0	-1.6	-0.2	-1.1	-0.2	-2.0
Townsend deprivation index at recruitment	0.9	1.2	6.6	0.8	0.2	2.6	0.2	1.2	0.2	1.0	0.8	0.6	1.0
Number of incorrect matches in round	0.9	1.5	6.5	-1.1	-0.9	-0.6	0.4	-1.1	-2.5	-0.4	-0.7	1.5	-1.5
Financial difficulties in last 2 years	0.9	1.3	3.1	0.7	1.0	0.6	1.1	1.0	1.5	1.2	1.0	-0.8	1.8
Father’s age at death	0.9	1.2	4.5	1.5	1.6	2.1	0.2	1.3	0.6	-0.3	-0.7	-0.4	0.1
Arm fat mass (right)	0.9	3.5	11.2	0.9	0.5	1.2	-2.1	0.2	-1.5	-1.8	-3.3	1.8	-2.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	3.0	1.1	1.0	0.8	0.5	1.7	-0.9	-1.7	-1.6	0.7	-1.2
Medication: Amlodipine	0.9	1.2	4.6	0.1	0.5	0.5	-1.7	-0.4	1.3	0.9	2.1	-0.6	1.2
High blood pressure (siblings)	0.9	1.3	5.7	0.7	0.0	0.3	1.1	0.4	0.9	0.7	2.4	-1.9	0.9
Number of children fathered	0.9	1.0	4.0	1.1	0.3	-0.5	-0.9	-0.6	-1.4	-0.3	-1.0	-0.0	-2.0
Age at first live birth	0.9	1.6	4.6	-0.2	1.8	2.1	0.1	2.2	0.8	-1.2	0.3	0.7	0.7
Angina (self-reported)	0.9	1.2	4.4	0.9	0.2	-0.6	-1.6	-0.2	-1.6	-0.1	-1.0	-0.6	-2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	3.4	-1.0	-1.0	-1.3	-1.8	-0.4	0.0	-1.0	-0.7	-0.8	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	2.9	-1.5	-1.2	-1.7	-0.5	-0.9	-0.2	-0.6	-1.2	-0.7	0.0
Friendships satisfaction	0.9	1.1	6.3	-0.6	-0.1	0.3	0.8	1.2	1.2	-0.4	-0.1	2.5	0.5
Mother’s age at death	0.9	1.1	2.7	-1.6	-1.6	-1.5	0.5	-0.8	0.4	-1.3	-0.7	-0.7	0.5
Irritability	0.9	1.6	3.2	1.7	1.8	1.3	0.5	0.4	-0.4	0.8	1.6	-1.7	-1.2
Schizophrenia vs Biploar Disorder	0.8	1.1	3.7	-1.2	-1.9	-0.7	0.4	-0.6	0.7	-0.3	1.1	-0.7	1.6
Average weekly fortified wine intake	0.8	0.9	3.5	0.6	0.6	0.6	1.5	1.9	0.1	0.4	-0.0	1.5	0.1
Serious illness, injury or assault to yourself	0.8	1.0	3.7	0.6	0.4	0.5	-0.0	0.6	-1.4	-0.7	-1.6	0.5	-1.9
Hair/balding pattern: Pattern 2	0.8	1.0	2.4	-0.1	0.5	0.5	-1.3	-0.1	1.1	1.2	1.6	-1.0	1.2
Had other major operations	0.8	1.0	3.7	-0.3	-0.3	0.1	0.1	0.6	0.0	-1.8	-1.9	1.6	-0.3
Illnesses of siblings	0.8	1.2	4.6	-0.5	0.3	0.1	-1.4	-0.5	-0.9	-0.8	-2.1	1.7	-0.7
Time employed in main current job	0.8	0.9	4.4	0.7	0.9	0.3	-2.1	0.9	0.6	0.1	0.2	-1.2	0.8
Falls in the last year	0.8	1.1	3.6	1.1	0.7	1.1	-1.9	1.3	-1.1	0.4	-0.7	0.2	-0.8
Pulse rate	0.8	1.3	4.3	-0.4	-0.2	0.3	1.1	1.4	2.1	0.8	1.0	-1.0	1.7
Prospective memory result	0.8	0.9	3.8	1.8	0.8	1.0	-0.0	1.9	0.4	0.5	-0.2	0.2	0.5
Pulse wave Arterial Stiffness index	0.8	1.0	5.7	-0.4	0.2	0.4	2.4	0.9	-0.0	-0.0	-1.0	1.2	0.4
Smoking status: Current	0.8	1.2	3.4	-0.4	-0.4	0.8	1.8	0.6	1.0	0.5	1.8	-1.4	1.1
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.2	0.5	1.1	0.4	1.3	0.6	1.8	0.3	0.6	-0.8	1.6
Average weekly beer plus cider intake	0.8	1.1	4.2	0.8	0.1	0.7	0.5	-1.0	-1.8	-0.6	-0.6	-0.9	-2.1
Basal cell carcinoma (self-reported)	0.8	1.0	2.4	0.8	1.1	-0.2	1.4	0.7	0.8	1.2	1.5	0.1	0.8
Prostate Cancer	0.7	1.0	3.4	-0.1	0.9	1.0	1.2	1.3	-0.1	-1.0	-0.7	1.8	-0.6
Hypothyroidism (self reported)	0.7	1.7	7.7	0.8	-0.0	-0.1	0.6	-0.3	-2.1	-0.5	-1.3	1.1	-2.8
Respiratory disease	0.7	1.5	3.8	-0.8	-0.9	-0.4	-0.9	-0.6	-2.0	-1.2	-1.7	-0.2	-1.9
Diabetes (mother)	0.7	0.9	5.1	0.9	0.4	0.8	0.5	-0.4	0.3	0.9	1.0	-2.3	0.4
Maternal smoking around birth	0.7	0.9	3.9	-0.1	-0.9	-0.7	-0.6	-1.0	-0.8	-1.2	-0.1	-2.0	-0.9
Multivitamins +/- minerals	0.7	0.9	2.1	1.2	1.2	1.5	0.1	1.1	0.3	-1.0	-0.2	-1.4	-0.1
Chronic bronchitis/emphysema (father)	0.7	0.8	2.3	-0.5	-0.0	-0.1	-1.5	0.1	-0.8	-0.8	-1.2	1.3	-1.0
High blood pressure (mother)	0.7	1.0	3.5	-0.6	-0.5	-1.0	0.8	-0.9	1.9	-0.1	1.2	-0.2	1.4
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	3.1	-0.6	-1.0	-0.9	0.2	0.5	1.2	0.2	1.8	-1.4	0.8
Lung cancer (father)	0.7	0.8	2.1	-1.4	-1.0	-1.1	0.4	-1.1	-0.4	-0.3	0.9	-1.2	0.2
Worry too long after embarrassment	0.7	1.1	4.3	-1.0	-0.2	-0.3	2.1	0.2	1.4	-0.2	0.3	-1.4	1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.8	-1.3	-0.6	-1.2	-0.2	-1.2	-0.5	-0.5	0.8	-1.4	0.3
Health satisfaction	0.7	0.9	3.9	0.4	0.3	-0.2	-0.3	1.1	-0.6	-1.1	-2.0	1.1	-0.9
Chest pain or discomfort	0.7	1.0	5.8	0.4	-0.0	-0.4	-0.2	-0.8	-1.3	-0.5	-1.1	0.1	-2.4
Family relationship satisfaction	0.7	0.9	4.4	-0.4	-0.7	-0.0	1.3	-0.5	-0.6	-0.6	-0.6	2.1	-0.7
Leg pain on walking	0.7	0.8	2.7	0.3	-0.5	-0.7	-0.2	0.8	-0.8	-1.0	-1.6	-1.2	-0.8
Arm fat percentage (left)	0.7	2.9	6.3	2.0	2.1	2.3	-0.6	2.1	2.5	1.2	0.5	0.1	1.6
Hearing aid user	0.7	0.8	1.8	-0.3	-0.1	-0.9	1.1	1.4	1.1	-0.5	0.4	1.0	1.1
Fractured/broken bones in last 5 years	0.7	0.9	2.2	1.5	0.9	0.7	-1.0	0.8	-0.6	0.0	-1.0	1.0	-1.3
Pack years of smoking	0.7	1.0	2.3	-0.7	-1.1	-1.0	1.3	-0.5	0.6	1.1	1.2	-0.2	1.5
Depression (Nagel 2018)	0.6	0.9	2.6	-0.3	-0.8	-0.0	1.6	0.5	-0.9	-1.4	-1.3	-0.3	-1.0
Major Depression (MDD)	0.6	0.8	4.4	-0.6	-0.7	0.4	2.1	0.5	1.1	-0.1	0.4	0.0	0.8
Mean Putamen Volume	0.6	0.7	1.8	-0.8	-0.8	-0.4	-0.8	0.9	-0.3	-1.3	-1.3	0.7	-0.5
Fasting Glucose	0.6	0.7	2.4	-1.5	-0.9	-0.9	1.4	-0.1	0.2	-0.1	-0.2	0.4	1.1
HbA1C	0.6	0.7	3.4	-0.4	-1.0	-1.0	1.9	-0.2	0.1	-0.4	-0.7	-0.5	0.4
Lung FEV1/FVC ratio	0.6	3.0	11.0	0.2	0.4	-0.1	-1.0	0.3	2.0	1.7	3.2	-0.4	3.3
Vitamin and mineral supplements	0.6	0.9	2.7	-0.8	-0.2	-0.8	-0.1	-0.9	0.8	1.6	1.3	0.8	1.0
Diabetes (father)	0.6	0.8	3.6	-0.6	0.2	-0.9	-0.6	0.2	0.4	-1.1	-1.9	0.9	0.3
Pack years adult smoking proportion	0.6	0.9	1.8	-0.6	-1.2	-1.2	1.3	-0.7	0.4	1.0	1.1	0.2	1.2
Taking other prescription medications	0.6	0.9	2.9	0.9	0.9	1.1	0.3	1.1	0.8	0.8	0.8	-1.7	0.0
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.0	0.2	0.5	0.2	-1.1	0.3	-1.1	-0.4	-0.9	1.4	-1.2
High blood pressure	0.6	1.7	3.5	1.2	1.4	1.9	-1.6	1.3	1.6	0.8	1.2	0.1	0.8
Supplements: Glucosamine	0.6	0.8	4.5	0.4	0.7	1.1	-0.9	-0.1	0.6	-0.2	0.9	-2.1	0.3
Medication: Atenolol	0.6	0.8	3.5	-0.0	0.0	0.5	-1.9	-0.5	-0.9	-0.8	0.1	-1.5	-0.6
Nervous feelings	0.6	1.1	4.7	0.3	1.2	-0.0	0.2	0.5	2.2	0.6	1.6	0.1	1.0
Arm fat percentage (right)	0.6	2.2	4.9	1.7	1.8	2.1	-0.9	1.8	2.2	1.0	0.4	-0.3	1.4
Worrier / anxious feelings	0.6	1.2	4.7	0.9	1.1	0.3	0.2	0.6	-1.0	-0.9	-1.3	1.1	-2.2
Number of live births	0.6	0.8	2.6	-0.4	-0.9	-1.6	0.1	-0.3	-0.5	-1.6	-1.2	0.2	-0.5
Illnesses of mother	0.6	0.7	3.5	0.7	0.0	0.7	-0.3	-0.3	-1.9	0.7	0.1	0.6	-1.1
Glaucoma (self-reported)	0.6	0.7	2.8	-0.2	0.2	0.2	-1.7	-1.0	-0.8	-1.0	-0.5	0.7	-0.9
Exposure to tobacco smoke outside home	0.6	0.8	2.6	1.0	0.8	1.4	0.0	0.6	-1.6	0.0	-0.6	-0.7	-0.6
Number of full brothers	0.6	0.7	3.5	-0.7	-1.5	-0.7	0.4	-1.9	-0.6	-0.2	0.2	-0.3	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.2	0.8	1.1	1.1	0.7	1.5	-0.4	-0.4	-0.9	0.4	-0.7
Eye problems/disorders: None of the above	0.6	0.7	2.5	1.4	1.6	0.7	0.5	0.1	-0.6	1.0	-0.1	0.4	-0.7
Number of full sisters	0.6	0.8	2.8	1.7	-0.0	0.1	-1.5	-0.2	-0.8	1.0	0.3	-0.5	-0.8
Knee pain experienced in last month	0.6	1.0	3.2	0.4	-0.4	-1.0	-1.8	-0.8	-1.2	-0.4	-0.3	0.7	-1.6
Hypertension (Self-reported)	0.6	1.7	4.8	1.2	1.2	1.8	-2.2	1.3	1.4	0.8	1.2	-0.0	0.8
Alcohol drinker status: Never	0.6	0.7	2.1	0.4	0.6	-0.7	0.0	0.7	0.5	1.0	1.2	-0.9	1.4
Age started oral contraceptive pill	0.6	0.8	2.0	-0.3	0.9	1.2	0.7	0.9	1.4	0.2	0.8	-0.3	1.3
Myopia	0.6	0.9	3.8	-0.5	0.3	-0.1	-0.4	0.0	-0.8	-2.0	-1.6	1.1	-0.5
Vascular/heart problems diagnosed by doctor	0.6	1.5	3.5	-1.5	-1.5	-1.9	1.9	-1.4	-0.9	-0.7	-0.7	-0.3	-0.1
Irritable Bowel Disease (IBD)	0.5	1.2	3.9	0.7	0.9	-0.0	-1.3	-2.0	-1.3	0.9	0.6	0.2	-1.5
Ulcerative Colitis (UC)	0.5	1.0	5.3	-0.3	-0.0	-0.6	-0.6	-2.3	-0.7	0.8	1.2	0.1	-1.1
Waist Hip Ratio (WHR)	0.5	2.2	5.8	0.9	1.3	2.4	1.5	2.2	-0.8	-1.4	-1.5	1.2	-0.5
Average weekly spirits intake	0.5	0.7	1.5	0.2	0.9	0.1	-0.6	0.9	1.2	1.0	0.4	-0.8	1.2
Stomach or abdominal pain in last month	0.5	0.6	2.5	0.4	0.4	-0.1	-1.6	0.0	0.2	-1.0	0.0	-0.9	-1.4
Hearing difficulty/problems with background noise	0.5	0.8	3.3	-0.7	-0.9	-0.0	-1.7	0.0	0.3	-1.8	-0.6	-0.3	-0.3
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.2	0.6	0.0	0.7	-0.3	1.2	-0.3	-0.4	-1.5	-0.4	-0.9
Medication: Ramipril	0.5	0.6	3.0	-0.6	-0.9	-1.1	-1.7	-0.8	-0.0	0.1	0.0	-0.1	-0.4
Happiness	0.5	0.7	2.0	0.6	0.6	0.6	0.9	1.4	0.3	-0.8	-1.2	0.6	-0.5
Mouth/teeth dental problems: Dentures	0.5	0.8	2.5	1.6	1.0	0.3	0.0	1.5	-0.8	0.7	-0.8	0.4	-1.0
Medication: Cholesterol lowering	0.5	0.8	4.8	-0.4	-0.1	-0.2	-2.2	0.3	0.9	-0.1	-0.4	-1.3	0.6
Breastfed as a baby	0.5	0.6	2.8	0.1	-0.3	-1.1	-0.0	-0.2	0.7	1.7	0.9	-0.3	0.5
Gout (self-reported)	0.5	0.6	1.6	0.1	-0.5	0.6	-1.0	-0.1	-1.3	-1.2	-0.8	-0.3	-1.1
Emphysema/chronic bronchitis	0.5	0.5	1.3	-0.6	-1.0	-1.1	-0.4	-0.9	-0.7	0.3	0.2	-0.4	-1.1
Had major operations	0.5	0.5	1.6	0.0	0.4	0.2	1.3	0.5	1.0	0.6	0.5	-0.0	1.3
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.2	-0.8	-1.0	-0.2	-0.1	-1.4	0.4	-0.1	0.4	1.5	0.0
Illnesses of siblings: Diabetes	0.5	0.6	2.3	0.7	0.3	0.4	0.7	-0.8	0.7	0.8	1.0	-1.5	-0.1
Smoking status: Previous	0.5	0.8	3.6	-0.6	-0.7	-0.6	0.2	-0.8	0.7	0.4	0.4	-1.9	1.3
Qualifications: nursing, teaching	0.5	0.7	1.5	1.0	0.8	0.8	0.6	0.7	-0.7	0.4	-0.9	0.9	-1.2
Guilty feelings	0.5	0.8	1.7	-0.7	-0.2	0.3	1.2	-1.2	-0.7	-1.2	-0.6	0.7	-1.3
Medication: Lisinopril	0.5	0.6	3.3	0.2	0.1	0.2	-0.7	-0.1	1.4	0.2	0.6	-1.8	0.2
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.2	-1.2	-0.8	-0.3	0.8	0.1	0.2	-1.5	-0.7	-0.3	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.4	0.3	0.9	0.1	-0.8	0.3	0.9	0.5	1.6	-1.1	0.2
Worry (Nagel 2018)	0.4	0.8	3.2	0.4	1.0	-0.4	1.8	0.5	1.2	0.5	1.0	-0.1	0.1
Crohns Disease (2017)	0.4	0.8	2.0	1.3	1.4	0.9	-0.4	-0.7	-1.2	0.6	-0.3	0.2	-1.0
Age at First Birth	0.4	0.6	3.1	-0.5	0.2	0.4	-0.1	0.3	-0.2	-1.2	-0.2	1.8	-0.5
LDL Cholesterol	0.4	0.7	2.8	-0.4	-0.7	-1.7	0.6	-0.6	0.1	0.1	0.6	-1.4	0.3
Blood Red Count	0.4	3.7	9.2	2.0	2.7	3.0	0.4	3.0	1.0	0.3	-1.6	2.0	0.0
Neuroticism	0.4	1.1	3.5	-0.5	0.1	0.0	1.9	-0.2	1.6	0.9	1.2	-1.2	0.6
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.9	0.1	0.0	0.1	1.4	0.5	-0.5	-1.0	-0.9	0.1	-1.1
Hearing difficulty/problems: Yes	0.4	0.6	1.5	-0.1	-0.3	0.6	-0.9	0.9	-0.0	-1.2	-1.1	0.6	-0.7
Trunk fat percentage	0.4	1.6	3.2	1.0	1.3	1.8	-1.1	1.8	1.8	0.0	-0.9	1.0	0.8
Past tobacco smoking	0.4	0.8	4.9	0.8	0.7	0.1	-0.2	1.0	-0.4	0.0	-0.1	2.2	-0.8
Pain all over the body in last month	0.4	0.4	1.2	0.2	0.4	0.7	0.9	0.5	-1.1	-0.5	-0.3	0.3	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	2.8	0.2	-0.1	0.3	-1.3	0.1	-0.8	-0.4	-1.2	-0.5	-1.7
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.5	0.7	0.5	-0.9	-0.4	1.2	0.4	0.2	0.2	-0.9	0.2
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.0	1.4	0.7	0.0	0.5	0.7	-0.4	0.6	-0.6	-0.8	-0.5
Body fat percentage	0.4	1.6	4.7	1.0	1.3	1.6	-1.0	1.6	2.2	0.4	-0.2	0.5	1.3
Medication: Allopurinol	0.4	0.5	1.9	0.0	-0.1	0.7	-1.4	-0.7	0.0	-0.5	0.2	-1.2	-0.4
Medication: Omeprazole	0.4	0.4	2.1	0.1	0.2	0.2	-0.4	-0.3	0.2	0.2	1.4	-1.3	-0.1
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.5	-1.0	-0.4	0.1	1.6	0.5	-0.6	0.1	-0.1	-0.8	0.5
Osteoporosis (self-reported)	0.4	0.6	1.2	0.5	0.4	0.6	-0.9	0.9	-0.7	-1.1	-1.1	-0.0	-0.7
Osteoarthritis (self-reported)	0.4	0.5	1.8	-0.3	-0.4	-0.2	0.1	0.5	-0.1	-1.3	-1.1	-1.2	0.6
Number of self-reported non-cancer illnesses	0.4	0.7	2.2	0.7	1.1	1.5	-0.3	1.0	0.8	-0.5	0.1	-1.2	-0.4
Miserableness	0.4	0.7	2.5	1.0	0.8	1.6	1.3	0.9	0.1	0.1	-0.1	0.4	-0.6
Financial situation satisfaction	0.4	0.4	0.9	-0.3	0.0	-0.7	0.8	0.7	0.9	-0.4	-1.0	0.8	0.0
Eye problems/disorders: Glaucoma	0.4	0.5	3.5	0.1	0.5	-0.0	-1.9	-0.2	0.1	-0.8	-0.3	-0.3	-0.1
Medication: Blood pressure	0.4	0.7	3.7	0.7	0.0	0.6	-1.9	0.1	-0.5	-0.8	-0.4	0.6	-1.1
Number of operations (self-reported)	0.4	0.6	2.1	0.7	0.6	-0.3	0.6	0.7	-0.6	-0.0	-1.5	1.1	-0.6
Neuroticism (Nagel 2018)	0.3	0.6	3.9	0.1	0.5	-0.5	2.0	-0.0	0.9	-0.2	0.3	-0.7	-0.5
Crohns Disease (2012)	0.3	0.4	1.3	0.4	0.1	0.8	-0.3	-0.9	-1.1	-0.0	-0.7	0.3	-0.7
HDL Cholesterol	0.3	0.4	1.0	-0.8	-0.3	-0.8	0.1	0.5	0.8	-0.4	0.9	-0.5	1.0
Blood Eosinophil Count	0.3	2.3	5.8	2.4	1.6	1.9	0.7	1.5	-1.7	-0.0	-1.6	1.2	-1.4
Allergy or Eczema	0.3	0.8	2.6	1.0	1.0	0.7	0.7	1.2	1.6	0.7	0.5	-0.7	0.5
Tanning	0.3	3.5	11.6	-1.7	-1.8	-3.4	-1.6	-1.8	-0.5	-1.6	-1.9	-0.2	-2.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.2	-0.2	-0.2	0.6	0.2	0.8	-0.2	-1.1	-0.7	0.5	-0.7
Medication: Levothyroxine sodium	0.3	0.5	1.5	0.8	1.0	0.7	1.2	0.8	0.3	0.2	-0.1	-0.2	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.2	0.2	-0.3	-0.3	1.5	0.4	-0.9	-0.2	-0.5	-0.8	-0.8
Had menopause	0.3	0.4	1.4	-0.7	-0.6	-1.2	-0.4	-0.2	0.0	-0.8	-0.4	0.6	0.3
Neuroticism score	0.3	0.6	2.3	-0.3	0.4	-0.2	1.5	0.0	1.5	0.1	0.9	-0.5	0.2
Loud music exposure frequency	0.3	0.3	0.7	-0.4	-0.4	0.5	0.7	-0.3	0.5	-0.4	0.8	-0.6	0.6
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	3.1	-0.0	-0.3	-0.2	0.6	-0.7	-1.3	-0.3	-0.7	0.5	-1.8
Comparative body size at age 10	0.3	0.9	2.2	1.1	0.3	0.8	0.6	-1.3	-1.5	-0.5	0.1	-1.1	-1.3
Wheeze or whistling in the chest in last year	0.3	0.5	1.8	0.0	0.3	0.2	0.3	0.6	1.4	-0.4	0.7	-0.9	0.8
Medication: Seretide 50 evohaler	0.3	0.3	0.8	0.5	0.1	0.8	0.4	0.6	-0.7	-0.1	-0.4	-0.3	-0.9
Alcohol intake frequency.	0.3	0.8	2.0	0.4	-0.2	-0.8	1.4	0.3	0.9	1.1	1.2	-0.1	1.2
Illnesses of father: Heart disease	0.3	0.4	0.8	0.4	0.4	0.6	-0.9	-0.3	-0.0	-0.8	-0.7	-0.9	-0.7
Loneliness, isolation	0.3	0.4	1.6	0.6	0.2	-0.1	0.7	-0.2	0.2	-0.7	-1.3	0.8	-0.5
Commuting to job workplace: Walk	0.3	0.4	1.5	-0.2	-0.5	1.1	0.1	-0.4	1.2	-0.3	0.1	0.7	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	2.0	0.3	0.3	0.0	-0.2	-0.4	-1.0	-0.6	0.2	-0.4	-1.4
Back pain experienced in last month	0.3	0.5	1.6	-0.2	-0.6	-0.6	-0.9	-1.1	-0.3	-0.1	0.7	-1.2	-0.3
Medication: Gliclazide	0.3	0.3	0.7	-0.8	-0.8	-0.5	0.6	0.6	0.4	-0.2	0.0	-0.8	0.5
Commuting to job workplace: Cycle	0.3	0.4	1.7	0.4	0.9	1.3	0.2	0.5	-0.1	0.0	0.1	0.9	0.0
Heart disease (siblings)	0.3	0.4	1.0	0.3	-0.6	-0.2	0.1	0.4	-0.5	-1.0	-1.0	-0.3	-0.9
Depressed Affect (Nagel 2018)	0.2	0.4	1.9	0.0	-0.1	-0.6	1.4	-0.4	0.9	-0.0	-0.3	-1.0	-0.3
Rheumatoid Arthritis	0.2	0.3	1.1	-0.1	-0.4	-0.5	-0.1	0.4	-0.1	1.1	0.8	-0.4	0.3
Triglycerides	0.2	0.3	2.1	-0.3	-0.1	0.0	-0.4	-0.4	0.4	0.5	0.3	-1.4	0.6
BMI	0.2	1.4	3.8	1.2	0.5	0.9	-0.9	0.7	-0.8	-0.9	-1.9	1.8	-1.4
Medication: Co-codamol	0.2	0.2	1.1	0.1	-0.0	-0.0	-0.8	0.7	0.1	-0.0	-0.1	-1.1	0.1
Medication: Metformin	0.2	0.3	1.3	-0.1	0.2	0.0	0.9	1.1	0.6	0.5	-0.8	0.4	0.1
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.8	-0.1	-0.3	-0.1	0.9	0.2	1.3	0.0	0.5	-1.1	0.5
Body mass index (BMI)	0.2	0.9	2.3	1.2	0.7	0.7	-1.5	0.2	-0.2	-0.4	-1.4	0.8	-1.1
Allergy	0.2	0.5	2.7	0.8	1.0	0.5	-0.1	0.8	-0.2	0.2	-0.0	1.6	0.5
Diabetes (self-reported)	0.2	0.3	0.8	0.1	0.6	-0.3	-0.1	0.9	0.7	0.7	-0.2	0.2	0.8
Medication: Simvastatin	0.2	0.3	0.9	-0.6	-0.0	-0.0	-0.4	-0.1	0.9	-0.3	0.1	-0.8	0.9
Depression (self-reported)	0.2	0.3	1.5	0.3	0.0	0.1	1.2	0.2	-0.1	-0.8	0.1	0.4	-0.1
Leg fat percentage (right)	0.2	0.9	3.1	0.9	0.9	0.8	-0.8	1.1	1.8	0.3	0.1	-0.1	1.1
Shortness of breath walking on level ground	0.2	0.3	0.8	0.9	0.4	0.1	0.1	0.6	0.1	0.7	0.4	-0.8	0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.3	1.1	0.6	0.2	0.2	0.3	-0.5	-1.1	-0.1	-0.1	-0.5	-0.9
Medication: Aspirin	0.2	0.3	1.6	0.1	-0.3	-0.5	-1.2	0.1	0.6	-0.3	-0.4	-0.6	0.3
Medication: Aspirin	0.2	0.3	0.9	-0.2	-0.7	-0.5	-1.0	0.0	0.2	-0.4	-0.8	-0.4	0.1
Tinnitus: Yes, now most or all of the time	0.2	0.2	1.2	-0.1	0.1	0.1	-0.3	1.1	0.3	-0.2	0.2	0.1	0.6
Leg fat percentage (left)	0.2	0.8	2.6	1.1	1.1	0.9	-0.7	0.9	1.6	0.2	-0.0	-0.4	0.9
Supplements: Calcium	0.2	0.2	0.6	0.0	0.6	0.2	0.4	-0.3	0.2	0.0	0.8	0.6	0.7
Type 2 Diabetes (T2D) (2018)	0.1	0.3	0.8	-0.2	0.4	-0.3	-0.2	0.7	0.9	0.1	-0.6	-0.5	0.7
Fed-up feelings	0.1	0.3	0.6	-0.8	-0.7	-0.7	0.3	-0.7	0.6	-0.4	0.2	0.2	-0.2
Asthma	0.1	0.1	0.4	-0.1	-0.3	0.4	0.0	0.1	-0.3	-0.2	0.2	-0.6	-0.5
Medication: Ventolin 100micrograms inhaler	0.1	0.2	1.2	0.2	-0.2	0.0	-1.1	-0.1	-0.5	0.1	-0.2	-0.1	-0.2
Average weekly red wine intake	0.1	0.2	0.8	-0.9	-0.7	-0.3	0.2	-0.4	0.1	-0.5	-0.4	0.2	-0.0
Diabetes diagnosed by doctor	0.1	0.2	1.0	-0.1	0.4	-0.0	-0.6	0.9	0.2	-0.3	-1.0	0.1	0.0
Asthma (self-reported)	0.1	0.2	0.5	-0.3	-0.6	0.3	0.0	-0.0	-0.6	-0.5	-0.2	-0.7	-0.7
Hair Pigment	0.0	0.5	1.8	0.1	0.4	0.9	0.1	-1.3	-0.7	-0.2	-0.6	1.3	-0.2

Hub : Genes

SCMH1

Models

Trait associations