TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
:
←
→
chr8:135,106,207-136,500,554
Best TWAS P=1.1e-09 · Best GWAS P=2.15e-10 conditioned to 0.0334
135.2M
135.4M
135.6M
135.8M
136M
136.2M
136.4M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Tibial
AC083843.1
0.21
0.16
lasso
6
0.14
1.9e-11
-5.3
6.1
1.1e-09
-0.87
0.01
0.99
TRUE
4
GTEx
Nerve Tibial
AC083843.1
0.16
0.16
lasso
2
0.14
3.5e-10
-5.3
5.6
2.5e-08
-0.82
0.10
0.90
FALSE
3
GTEx
Esophagus Muscularis
AC083843.1
0.17
0.21
lasso
3
0.20
2.5e-12
-5.3
5.4
8.8e-08
-0.78
0.34
0.66
FALSE
2
GTEx
Esophagus Mucosa
AC083843.1
0.15
0.09
lasso
2
0.09
1.0e-06
-5.3
5.3
1.2e-07
-0.78
0.17
0.83
FALSE