Best TWAS P=1.1e-09 · Best GWAS P=2.15e-10 conditioned to 0.0334
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | AC083843.1 | 0.21 | 0.16 | lasso | 6 | 0.14 | 1.9e-11 | -5.3 | 6.1 | 1.1e-09 | -0.87 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Esophagus Mucosa | AC083843.1 | 0.15 | 0.09 | lasso | 2 | 0.09 | 1.0e-06 | -5.3 | 5.3 | 1.2e-07 | -0.78 | 0.17 | 0.83 | FALSE |
| 3 | GTEx | Esophagus Muscularis | AC083843.1 | 0.17 | 0.21 | lasso | 3 | 0.20 | 2.5e-12 | -5.3 | 5.4 | 8.8e-08 | -0.78 | 0.34 | 0.66 | FALSE |
| 4 | GTEx | Nerve Tibial | AC083843.1 | 0.16 | 0.16 | lasso | 2 | 0.14 | 3.5e-10 | -5.3 | 5.6 | 2.5e-08 | -0.82 | 0.10 | 0.90 | FALSE |