TWAS
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Traits
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Forced expiratory volume in 1-second (FEV1), Best measure
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chr9:97,945,796-99,474,182
Best TWAS P=1.21e-07 · Best GWAS P=4.63e-07 conditioned to 2.92e-07
98M
98.2M
98.4M
98.6M
98.8M
99M
99.2M
99.4M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Esophagus Muscularis
ERCC6L2
0.15
0.10
lasso
6
0.08
8.8e-06
4.7
5.3
1.2e-07
-0.02
0.09
0.88
TRUE
1
GTEx
Artery Tibial
ERCC6L2
0.22
0.18
enet
39
0.18
5.2e-14
4.6
5.2
2.2e-07
-0.04
0.10
0.89
FALSE