TWAS
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Traits
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Traits
:
Forced expiratory volume in 1-second (FEV1), Best measure
:
←
→
chr13:110,598,964-112,060,514
Best TWAS P=2.56e-07 · Best GWAS P=2.11e-07 conditioned to 0.0624
110.6M
110.8M
111M
111.2M
111.4M
111.6M
111.8M
112M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Thyroid
CARS2
0.28
0.14
lasso
11
0.13
3.8e-10
4.8
-5.2
2.6e-07
-0.78
0.02
0.97
TRUE