[Hub]/) : Traits : Forced expiratory volume in 1-second (FEV1), Best measure :

chr13:49,557,805-51,390,447

Best TWAS P=1.23e-14 · Best GWAS P=1.25e-14 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TRIM13 0.15 0.04 lasso 5 0.12 1.1e-14 7.6 -6.6 4.0e-11 -0.80 0.01 0.99 FALSE
2 GTEx Esophagus Gastroesophageal Junction EBPL 0.27 0.24 enet 14 0.26 4.6e-10 5.9 -5.9 3.0e-09 -0.30 0.94 0.06 FALSE
3 GTEx Nerve Tibial DLEU2 0.11 0.05 lasso 3 0.02 7.8e-03 7.7 7.7 1.2e-14 0.99 0.01 0.98 TRUE
4 GTEx Pancreas EBPL 0.18 0.10 enet 5 0.09 1.6e-04 7.2 -5.3 1.1e-07 -0.23 0.19 0.51 TRUE
5 GTEx Pituitary EBPL 0.44 0.32 enet 29 0.37 3.1e-10 6.0 -5.7 9.5e-09 -0.37 0.67 0.28 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic EBPL 0.34 0.26 enet 12 0.30 4.0e-17 6.0 -6.0 1.8e-09 -0.26 0.96 0.04 FALSE
7 GTEx Skin Sun Exposed Lower leg EBPL 0.28 0.21 lasso 5 0.20 2.5e-16 5.9 -6.3 2.4e-10 -0.32 1.00 0.00 FALSE
8 GTEx Testis EBPL 0.33 0.17 lasso 6 0.24 8.4e-11 5.9 -7.3 2.5e-13 -0.32 0.76 0.24 TRUE
9 GTEx Thyroid EBPL 0.36 0.14 enet 33 0.30 5.1e-23 5.9 -5.2 2.4e-07 -0.31 0.70 0.30 TRUE
10 YFS Blood KPNA3 0.04 0.02 bslmm 427 0.02 1.4e-08 3.5 5.4 7.0e-08 0.34 1.00 0.00 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DLEU2 0.03 0.01 blup 61 0.02 2.4e-03 7.6 7.5 9.0e-14 0.90 0.01 0.96 TRUE
12 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma EBPL 0.28 0.18 blup 59 0.19 4.3e-08 5.9 -5.4 6.4e-08 -0.23 0.01 0.98 TRUE
13 The Cancer Genome Atlas Prostate Adenocarcinoma EBPL 0.08 0.01 blup 59 0.04 6.4e-05 5.9 -6.5 7.6e-11 -0.27 0.01 0.89 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma KPNA3 0.05 0.02 blup 75 0.04 4.6e-05 -4.9 -5.6 2.4e-08 -0.25 0.47 0.05 FALSE