Best TWAS P=4.38e-10 · Best GWAS P=5.66e-17 conditioned to 5.76e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | LOXL1-AS1 | 0.28 | 0.09 | lasso | 6 | 0.17 | 1.7e-12 | 3.0 | 5.4 | 7.2e-08 | -0.64 | 0.99 | 0.01 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | LOXL1-AS1 | 0.11 | 0.05 | enet | 11 | 0.10 | 7.3e-09 | 1.7 | 5.4 | 8.1e-08 | -0.41 | 0.83 | 0.07 | FALSE |
| 3 | GTEx | Testis | LOXL1-AS1 | 0.36 | 0.15 | lasso | 10 | 0.13 | 2.4e-06 | -6.0 | -6.2 | 4.4e-10 | 0.58 | 0.51 | 0.08 | TRUE |
| 4 | GTEx | Thyroid | LOXL1-AS1 | 0.15 | 0.03 | enet | 40 | 0.03 | 2.6e-03 | -6.0 | 6.2 | 4.9e-10 | -0.33 | 0.12 | 0.24 | FALSE |