[Hub]/) : Traits : Forced vital capacity (FVC), Best measure :

chr2:135,898,023-137,435,625

Best TWAS P=8.78e-11 · Best GWAS P=3.08e-08 conditioned to 0.0132

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Mucosa DARS 0.12 0.05 lasso 4 0.04 9.0e-04 5.1 5.3 1.3e-07 -0.49 0.06 0.86 FALSE
2 GTEx Esophagus Muscularis DARS 0.12 0.11 lasso 3 0.09 3.5e-06 5.1 5.2 2.3e-07 -0.48 0.06 0.94 FALSE
3 GTEx Lung DARS 0.07 0.05 lasso 4 0.05 5.8e-05 5.0 5.1 2.9e-07 -0.48 0.06 0.93 FALSE
4 GTEx Nerve Tibial DARS 0.13 0.06 lasso 5 0.05 3.2e-04 5.1 5.1 2.9e-07 -0.49 0.06 0.92 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic DARS 0.15 0.11 enet 4 0.10 3.0e-06 5.0 5.2 1.5e-07 -0.48 0.06 0.94 FALSE
6 GTEx Thyroid DARS 0.20 0.13 lasso 3 0.15 1.3e-11 5.1 5.3 1.3e-07 -0.50 0.07 0.92 FALSE
7 METSIM Adipose DARS 0.09 0.07 blup 311 0.09 4.6e-13 5.3 5.2 1.6e-07 -0.38 0.04 0.96 FALSE
8 NTR Blood MCM6 0.02 0.02 lasso 2 0.03 1.2e-08 4.2 5.2 2.4e-07 -0.55 0.07 0.93 FALSE
9 YFS Blood DARS 0.17 0.19 enet 36 0.19 8.2e-60 5.3 6.5 8.8e-11 -0.53 0.03 0.97 TRUE
10 The Cancer Genome Atlas Breast Invasive Carcinoma LCT 0.02 0.02 enet 3 0.03 7.6e-07 4.6 -5.1 3.1e-07 0.55 0.04 0.96 FALSE
11 The Cancer Genome Atlas Pancreatic Adenocarcinoma DARS 0.08 0.10 lasso 4 0.09 8.8e-05 5.1 5.2 2.6e-07 -0.49 0.02 0.94 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma DARS 0.04 0.02 blup 40 0.01 2.1e-02 5.0 5.9 4.0e-09 -0.52 0.02 0.93 FALSE
13 The Cancer Genome Atlas Soft Tissue Sarcoma DARS 0.04 0.04 blup 40 0.04 1.6e-03 5.0 5.3 9.7e-08 -0.53 0.02 0.92 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma DARS 0.22 0.15 enet 13 0.19 4.1e-18 5.0 5.3 1.2e-07 -0.39 0.03 0.97 FALSE