Best TWAS P=1.23e-09 · Best GWAS P=5.79e-11 conditioned to 0.000595
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | YFS | Blood | H1FX | 0.02 | 0.01 | lasso | 3 | 0.01 | 1.4e-03 | -5.9 | 6.0 | 2.0e-09 | -0.84 | 0.05 | 0.73 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | H1FX | 0.02 | 0.02 | lasso | 5 | 0.03 | 6.5e-07 | 3.4 | 5.9 | 4.0e-09 | -0.62 | 0.10 | 0.88 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | H1FX | 0.02 | 0.00 | blup | 36 | 0.00 | 5.1e-01 | -6.5 | 6.1 | 1.2e-09 | -0.65 | 0.01 | 0.66 | TRUE |