[Hub]/) : Traits : Forced vital capacity (FVC), Best measure : ← →

chr4:644,410-2,058,475

Best TWAS P=5.36e-09 · Best GWAS P=8.7e-07 conditioned to 0.202

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Brain Cortex	CRIPAK	0.34	0.10	lasso	6	0.18	9.5e-06	-4.7	-5.8	5.4e-09	0.68	0.01	0.85	TRUE
2	GTEx	Adipose Visceral Omentum	CRIPAK	0.47	0.24	lasso	12	0.31	1.3e-16	-4.7	-5.6	2.1e-08	0.76	0.01	0.98	FALSE
17	NTR	Blood	CRIPAK	0.13	0.09	enet	31	0.15	1.5e-46	-4.0	-5.5	3.1e-08	0.70	0.10	0.73	FALSE
6	GTEx	Brain Hypothalamus	CRIPAK	0.22	0.00	lasso	5	0.01	2.1e-01	-4.6	-5.5	5.1e-08	0.77	0.01	0.47	FALSE
10	GTEx	Lung	CRIPAK	0.61	0.22	enet	46	0.41	1.1e-33	-4.7	-5.4	5.6e-08	0.67	0.01	0.98	FALSE
15	METSIM	Adipose	CRIPAK	0.28	0.16	bslmm	335	0.25	2.7e-37	-4.9	-5.4	5.7e-08	0.71	0.00	0.99	FALSE
19	The Cancer Genome Atlas	Skin Cutaneous Melanoma	CRIPAK	0.57	0.07	enet	9	0.23	6.7e-07	-4.7	-5.3	9.1e-08	0.54	0.00	0.76	FALSE
14	GTEx	Whole Blood	CRIPAK	0.38	0.17	lasso	9	0.28	3.4e-26	-3.4	-5.3	1.1e-07	0.69	0.09	0.74	FALSE
5	GTEx	Brain Hippocampus	CRIPAK	0.48	0.22	lasso	4	0.23	4.0e-06	-3.4	-5.3	1.3e-07	0.61	0.03	0.54	FALSE
13	GTEx	Uterus	CRIPAK	0.52	0.34	lasso	3	0.33	1.7e-07	-4.6	-5.3	1.3e-07	0.81	0.01	0.85	FALSE
3	GTEx	Brain Caudate basal ganglia	CRIPAK	0.27	0.00	lasso	2	0.02	9.3e-02	-4.6	-5.3	1.4e-07	0.81	0.01	0.44	FALSE
18	YFS	Blood	CRIPAK	0.35	0.27	bslmm	301	0.33	6.0e-112	-3.4	-5.2	1.7e-07	0.72	0.25	0.29	FALSE
16	METSIM	Adipose	UVSSA	0.26	0.04	bslmm	366	0.12	9.0e-18	0.7	-5.2	1.9e-07	0.56	0.02	0.96	FALSE
11	GTEx	Muscle Skeletal	CRIPAK	0.25	0.11	enet	32	0.18	7.6e-18	-4.7	-5.2	2.3e-07	0.62	0.01	0.98	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	CRIPAK	0.49	0.27	lasso	8	0.35	2.9e-12	-4.7	-5.2	2.4e-07	0.67	0.01	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CRIPAK	0.31	0.15	enet	34	0.26	1.2e-31	-3.6	-5.2	2.5e-07	0.60	0.21	0.42	FALSE
7	GTEx	Brain Nucleus accumbens basal ganglia	CRIPAK	0.34	0.13	lasso	6	0.25	2.7e-07	-4.7	-5.2	2.5e-07	0.67	0.01	0.82	FALSE
9	GTEx	Esophagus Mucosa	CRIPAK	0.49	0.14	enet	28	0.40	6.8e-29	-4.7	-5.2	2.6e-07	0.66	0.01	0.98	FALSE
12	GTEx	Ovary	CRIPAK	0.43	0.27	enet	19	0.32	9.0e-09	-4.7	-5.1	2.8e-07	0.72	0.01	0.93	FALSE