[Hub]/) : Traits : Forced vital capacity (FVC), Best measure :

chr4:644,410-2,058,475

Best TWAS P=5.36e-09 · Best GWAS P=8.7e-07 conditioned to 0.202

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CRIPAK 0.31 0.15 enet 34 0.26 1.2e-31 -3.6 -5.2 2.5e-07 0.60 0.21 0.42 FALSE
2 GTEx Adipose Visceral Omentum CRIPAK 0.47 0.24 lasso 12 0.31 1.3e-16 -4.7 -5.6 2.1e-08 0.76 0.01 0.98 FALSE
3 GTEx Brain Caudate basal ganglia CRIPAK 0.27 0.00 lasso 2 0.02 9.3e-02 -4.6 -5.3 1.4e-07 0.81 0.01 0.44 FALSE
4 GTEx Brain Cortex CRIPAK 0.34 0.10 lasso 6 0.18 9.5e-06 -4.7 -5.8 5.4e-09 0.68 0.01 0.85 TRUE
5 GTEx Brain Hippocampus CRIPAK 0.48 0.22 lasso 4 0.23 4.0e-06 -3.4 -5.3 1.3e-07 0.61 0.03 0.54 FALSE
6 GTEx Brain Hypothalamus CRIPAK 0.22 0.00 lasso 5 0.01 2.1e-01 -4.6 -5.5 5.1e-08 0.77 0.01 0.47 FALSE
7 GTEx Brain Nucleus accumbens basal ganglia CRIPAK 0.34 0.13 lasso 6 0.25 2.7e-07 -4.7 -5.2 2.5e-07 0.67 0.01 0.82 FALSE
8 GTEx Cells EBV-transformed lymphocytes CRIPAK 0.49 0.27 lasso 8 0.35 2.9e-12 -4.7 -5.2 2.4e-07 0.67 0.01 0.98 FALSE
9 GTEx Esophagus Mucosa CRIPAK 0.49 0.14 enet 28 0.40 6.8e-29 -4.7 -5.2 2.6e-07 0.66 0.01 0.98 FALSE
10 GTEx Lung CRIPAK 0.61 0.22 enet 46 0.41 1.1e-33 -4.7 -5.4 5.6e-08 0.67 0.01 0.98 FALSE
11 GTEx Muscle Skeletal CRIPAK 0.25 0.11 enet 32 0.18 7.6e-18 -4.7 -5.2 2.3e-07 0.62 0.01 0.98 FALSE
12 GTEx Ovary CRIPAK 0.43 0.27 enet 19 0.32 9.0e-09 -4.7 -5.1 2.8e-07 0.72 0.01 0.93 FALSE
13 GTEx Uterus CRIPAK 0.52 0.34 lasso 3 0.33 1.7e-07 -4.6 -5.3 1.3e-07 0.81 0.01 0.85 FALSE
14 GTEx Whole Blood CRIPAK 0.38 0.17 lasso 9 0.28 3.4e-26 -3.4 -5.3 1.1e-07 0.69 0.09 0.74 FALSE
15 METSIM Adipose CRIPAK 0.28 0.16 bslmm 335 0.25 2.7e-37 -4.9 -5.4 5.7e-08 0.71 0.00 0.99 FALSE
16 METSIM Adipose UVSSA 0.26 0.04 bslmm 366 0.12 9.0e-18 0.7 -5.2 1.9e-07 0.56 0.02 0.96 FALSE
17 NTR Blood CRIPAK 0.13 0.09 enet 31 0.15 1.5e-46 -4.0 -5.5 3.1e-08 0.70 0.10 0.73 FALSE
18 YFS Blood CRIPAK 0.35 0.27 bslmm 301 0.33 6.0e-112 -3.4 -5.2 1.7e-07 0.72 0.25 0.29 FALSE
19 The Cancer Genome Atlas Skin Cutaneous Melanoma CRIPAK 0.57 0.07 enet 9 0.23 6.7e-07 -4.7 -5.3 9.1e-08 0.54 0.00 0.76 FALSE