Best TWAS P=4.4e-11 · Best GWAS P=1.45e-13 conditioned to 0.00425
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | CTB-36H16.2 | 0.12 | 0.15 | lasso | 3 | 0.12 | 2.6e-07 | -6.0 | 6.1 | 8.5e-10 | -0.05 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Artery Tibial | CTB-36H16.2 | 0.15 | 0.12 | lasso | 6 | 0.09 | 8.1e-08 | -5.2 | 5.3 | 1.5e-07 | 0.02 | 0.34 | 0.66 | FALSE |
| 3 | GTEx | Esophagus Muscularis | CTB-36H16.2 | 0.08 | 0.08 | lasso | 2 | 0.04 | 1.5e-03 | -5.2 | 5.2 | 1.8e-07 | 0.02 | 0.10 | 0.78 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CEP120 | 0.10 | 0.14 | blup | 70 | 0.14 | 2.6e-14 | -7.4 | 6.6 | 4.4e-11 | -0.83 | 0.01 | 0.99 | TRUE |