TWAS
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Traits
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Forced vital capacity (FVC), Best measure
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chr5:121,480,516-123,002,130
Best TWAS P=4.4e-11 · Best GWAS P=1.45e-13 conditioned to 0.00425
121.4M
121.6M
121.8M
122M
122.2M
122.4M
122.6M
122.8M
123M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
CEP120
0.10
0.14
blup
70
0.14
2.6e-14
-7.4
6.6
4.4e-11
-0.83
0.01
0.99
TRUE
1
GTEx
Artery Aorta
CTB-36H16.2
0.12
0.15
lasso
3
0.12
2.6e-07
-6.0
6.1
8.5e-10
-0.05
0.01
0.99
TRUE
2
GTEx
Artery Tibial
CTB-36H16.2
0.15
0.12
lasso
6
0.09
8.1e-08
-5.2
5.3
1.5e-07
0.02
0.34
0.66
FALSE
3
GTEx
Esophagus Muscularis
CTB-36H16.2
0.08
0.08
lasso
2
0.04
1.5e-03
-5.2
5.2
1.8e-07
0.02
0.10
0.78
FALSE