[Hub]/) : Traits : Forced vital capacity (FVC), Best measure :

chr5:126,587,995-128,220,643

Best TWAS P=4.15e-09 · Best GWAS P=5.86e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes CTC-228N24.3 0.24 -0.01 enet 26 0.04 2.2e-02 3.8 -5.4 8.6e-08 -0.57 0.04 0.58 TRUE
2 GTEx Esophagus Mucosa CTC-228N24.3 0.18 0.14 enet 11 0.14 9.8e-10 5.4 -5.2 2.4e-07 -0.93 0.01 0.99 FALSE
3 GTEx Lung CTC-228N24.3 0.18 0.14 enet 16 0.14 3.2e-11 5.4 -5.4 7.9e-08 -0.95 0.01 0.99 TRUE
4 GTEx Pancreas CTC-228N24.3 0.14 0.19 lasso 2 0.17 1.1e-07 5.4 -5.4 5.9e-08 -1.00 0.01 0.99 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic CTC-228N24.3 0.29 0.21 lasso 7 0.22 1.7e-12 5.4 -5.3 1.1e-07 -0.97 0.01 0.99 TRUE
6 GTEx Stomach SLC12A2 0.23 0.17 enet 19 0.17 1.6e-08 5.2 -5.5 4.9e-08 -0.45 0.03 0.97 TRUE
7 GTEx Stomach CTC-228N24.3 0.17 0.04 lasso 6 0.08 1.5e-04 4.3 -5.7 9.5e-09 -0.81 0.03 0.92 FALSE
8 METSIM Adipose CTC-228N24.3 0.17 0.19 lasso 6 0.18 1.9e-26 5.4 -5.3 1.2e-07 -1.00 0.01 0.99 FALSE
9 ROSMAP Brain Pre-frontal Cortex CTC-228N24.3 0.15 0.09 lasso 3 0.12 8.0e-15 5.4 -5.7 9.9e-09 -0.88 0.00 0.99 TRUE
10 The Cancer Genome Atlas Breast Invasive Carcinoma FLJ33630 0.05 0.04 enet 14 0.03 2.1e-07 5.4 -5.9 4.1e-09 -0.88 0.00 1.00 TRUE
11 The Cancer Genome Atlas Glioblastoma Multiforme FLJ33630 0.38 0.20 lasso 5 0.17 6.5e-06 5.4 -5.3 9.1e-08 -0.99 0.00 0.99 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FLJ33630 0.10 0.07 lasso 3 0.08 7.0e-09 4.8 -5.2 2.0e-07 -0.95 0.00 0.99 FALSE
13 The Cancer Genome Atlas Brain Lower Grade Glioma FLJ33630 0.19 0.16 enet 4 0.16 1.2e-17 5.4 -5.3 1.5e-07 -1.00 0.00 1.00 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma FBN2 0.11 0.12 blup 159 0.14 2.2e-16 -4.9 -5.7 1.2e-08 -0.16 0.05 0.95 TRUE
15 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FBN2 0.03 0.02 lasso 2 0.02 4.5e-03 -5.2 -5.3 1.3e-07 -0.17 0.03 0.91 FALSE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FLJ33630 0.09 0.08 lasso 4 0.09 4.9e-10 5.4 -5.3 1.0e-07 -1.00 0.00 1.00 FALSE
17 The Cancer Genome Atlas Pancreatic Adenocarcinoma FLJ33630 0.08 0.03 lasso 2 0.04 5.7e-03 4.8 -5.7 1.2e-08 -0.90 0.01 0.87 FALSE
18 The Cancer Genome Atlas Stomach Adenocarcinoma FBN2 0.09 0.04 blup 159 0.06 4.6e-05 -4.6 -5.3 1.1e-07 -0.25 0.07 0.90 TRUE
19 The Cancer Genome Atlas Testicular Germ Cell Tumors FLJ33630 0.26 0.14 lasso 3 0.13 2.2e-05 5.4 -5.5 3.7e-08 -0.99 0.00 0.99 FALSE
20 The Cancer Genome Atlas Thyroid Carcinoma FLJ33630 0.10 0.10 lasso 2 0.09 5.3e-09 5.4 -5.5 3.8e-08 -1.00 0.00 1.00 FALSE