TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced vital capacity (FVC), Best measure
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chr6:134,905,567-136,516,257
Best TWAS P=2.49e-09 · Best GWAS P=5.04e-08 conditioned to 0.234
135M
135.2M
135.4M
135.6M
135.8M
136M
136.2M
136.4M
136.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Cells EBV-transformed lymphocytes
AHI1
0.38
0.24
enet
19
0.23
5.4e-08
-4.6
6.0
2.5e-09
-0.79
0.07
0.92
TRUE
2
GTEx
Cells Transformed fibroblasts
AHI1
0.44
0.21
enet
22
0.32
4.4e-24
-5.0
5.2
1.8e-07
-0.81
0.03
0.96
FALSE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
C6orf217
0.02
0.02
blup
80
0.02
1.2e-05
-4.9
5.1
2.8e-07
-0.89
0.02
0.98
FALSE