Best TWAS P=2.49e-09 · Best GWAS P=5.04e-08 conditioned to 0.234
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | AHI1 | 0.38 | 0.24 | enet | 19 | 0.23 | 5.4e-08 | -4.6 | 6.0 | 2.5e-09 | -0.79 | 0.07 | 0.92 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | AHI1 | 0.44 | 0.21 | enet | 22 | 0.32 | 4.4e-24 | -5.0 | 5.2 | 1.8e-07 | -0.81 | 0.03 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | C6orf217 | 0.02 | 0.02 | blup | 80 | 0.02 | 1.2e-05 | -4.9 | 5.1 | 2.8e-07 | -0.89 | 0.02 | 0.98 | FALSE |