Best TWAS P=4.77e-12 · Best GWAS P=6.83e-10 conditioned to 0.00105
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | TULP4 | 0.44 | 0.37 | lasso | 12 | 0.32 | 4.3e-09 | 6.2 | 5.9 | 3.5e-09 | 0.98 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Brain Cerebellum | TULP4 | 0.46 | 0.32 | lasso | 15 | 0.28 | 7.6e-09 | 5.2 | 5.3 | 1.4e-07 | 0.91 | 0.19 | 0.81 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TULP4 | 0.09 | 0.05 | blup | 148 | 0.04 | 2.0e-05 | 5.8 | -6.9 | 4.8e-12 | -0.48 | 0.02 | 0.97 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TULP4 | 0.03 | 0.03 | lasso | 3 | 0.02 | 5.1e-03 | 6.1 | -6.2 | 6.6e-10 | -0.99 | 0.01 | 0.94 | FALSE |