Hub : Genes

TULP4

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1650	0.0380	2.7e-11	0.080	0.115	0.117	0.119	0.115	6.0e-10	7.1e-14	4.4e-14	2.9e-14	7.7e-14
2	GTEx	Adipose Visceral Omentum	0.1530	0.0650	8.7e-03	-0.004	NA	0.000	NA	-0.002	5.6e-01	NA	3.1e-01	NA	4.2e-01
3	GTEx	Brain Cerebellar Hemisphere	0.4370	0.0880	3.1e-07	0.370	NA	0.247	NA	0.324	1.9e-10	NA	5.2e-07	NA	4.3e-09
4	GTEx	Brain Cerebellum	0.4610	0.0850	1.1e-07	0.316	NA	0.201	NA	0.278	4.7e-10	NA	1.4e-06	NA	7.6e-09
5	GTEx	Esophagus Mucosa	0.3780	0.0750	3.7e-09	0.275	NA	0.290	NA	0.265	1.4e-18	NA	1.2e-19	NA	6.9e-18
6	GTEx	Muscle Skeletal	0.0757	0.0307	1.2e-03	0.010	NA	0.024	NA	0.013	3.5e-02	NA	1.9e-03	NA	1.6e-02
7	GTEx	Stomach	0.2510	0.0620	6.5e-07	0.180	NA	0.144	NA	0.165	5.2e-09	NA	2.3e-07	NA	2.7e-08
8	GTEx	Thyroid	0.0950	0.0340	1.3e-03	0.025	NA	0.011	NA	0.033	4.9e-03	NA	4.5e-02	NA	1.4e-03
9	ROSMAP	Brain Pre-frontal Cortex	0.0691	0.0262	1.2e-03	0.018	0.017	0.025	0.017	0.029	1.7e-03	2.8e-03	2.8e-04	2.7e-03	1.2e-04
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0879	0.0436	4.5e-04	0.046	0.041	0.037	NA	0.039	6.6e-06	2.0e-05	5.2e-05	NA	3.2e-05
11	TCGA	Brain Lower Grade Glioma	0.0320	0.0175	4.9e-03	0.028	0.015	0.009	NA	0.016	3.2e-04	7.4e-03	3.2e-02	NA	5.1e-03
12	TCGA	Prostate Adenocarcinoma	0.0569	0.0317	7.0e-03	0.014	0.007	0.016	NA	0.009	1.1e-02	5.7e-02	8.1e-03	NA	3.7e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bipolar Disorder (2018)	0.4	0.7	2.9	0.5	-0.3	1.2	0.9	-1.7	-0.0	-1.0	0.2	0.9	0.7	-0.8	0.2
Bipolar Disorder or Schizophrenia	0.2	0.4	1.3	0.0	-0.9	0.6	0.5	-1.0	-0.2	-1.1	0.8	-0.3	-0.3	-0.3	-0.3
Depressed Affect (Nagel 2018)	0.3	0.6	2.0	1.2	0.0	0.1	-0.4	0.8	-0.2	0.3	-0.4	-0.5	-1.4	-0.2	-1.4
Depression (Nagel 2018)	1.1	1.6	5.7	0.9	-0.3	1.1	0.6	-0.8	-1.4	-0.1	0.7	-2.0	-1.4	-1.2	-2.4
Intelligence (Savage-Jansen 2018)	1.5	4.5	19.4	2.1	-0.5	-0.7	-0.6	0.8	-1.1	-0.6	-2.1	3.5	4.4	1.4	2.9
Neuroticism (Nagel 2018)	0.4	0.9	3.8	2.0	0.3	0.1	-0.2	0.9	-0.9	-0.9	-1.3	0.4	-0.3	-0.0	-1.5
Schizophrenia (2018)	0.2	0.4	1.1	-0.5	-1.0	-0.2	-0.1	0.2	-0.2	-0.7	0.9	-1.1	-0.9	0.3	-0.5
Schizophrenia vs Biploar Disorder	1.6	2.1	5.9	1.3	0.4	-2.0	-2.4	2.0	-0.3	1.2	-1.8	0.2	-0.7	1.9	-0.7
Worry (Nagel 2018)	0.1	0.3	0.7	0.5	0.5	0.8	0.4	0.1	0.8	0.1	-0.5	0.7	-0.4	-0.5	0.1
Alzheimer’s Disease (in mother)	0.7	0.9	2.2	-1.2	0.3	-1.5	-0.9	0.3	-0.6	0.9	0.2	-1.4	0.7	1.3	0.6
Alzheimer’s Disease (in father)	1.4	1.6	2.8	1.4	1.7	-1.1	-1.5	1.5	-1.3	-0.0	-1.4	0.8	-0.1	1.1	-1.7
Alzheimer’s Disease (including proxy)	1.1	1.6	5.0	0.5	1.0	-2.1	-1.8	1.5	-1.5	0.7	-0.7	-0.2	0.9	2.2	-0.3
Crohns Disease (2017)	0.7	1.5	3.5	0.6	-0.5	-1.4	-0.7	0.6	-1.5	-1.9	-1.8	-0.1	1.7	1.4	-0.7
Irritable Bowel Disease (IBD)	0.5	1.3	3.5	0.3	0.5	-1.7	-1.3	1.1	-0.6	-1.0	-1.9	-0.7	0.6	1.5	-1.1
Ulcerative Colitis (UC)	0.5	1.0	2.6	0.0	1.2	-1.5	-1.6	1.3	0.4	0.3	-1.3	-0.7	-0.0	1.4	-0.3
Major Depression (MDD)	0.5	0.6	2.4	1.2	0.3	-0.4	0.1	-0.1	-0.9	-1.2	-0.7	0.5	1.6	0.6	0.2
Reaction Time	1.6	3.1	7.6	1.6	0.7	-2.1	-1.9	2.2	-1.0	-1.4	-2.1	2.8	0.9	2.0	-1.2
Verbal and Numeric Reasoning (VNR)	1.9	4.6	18.7	2.5	-0.1	-0.5	-0.4	0.5	-0.4	-1.1	-2.2	3.8	4.3	1.2	2.8
Breast Cancer	0.5	1.1	8.1	-0.6	0.8	0.9	0.8	-0.5	0.4	1.1	-0.2	0.9	0.9	-0.3	2.9
Ovarian Cancer	0.3	0.4	1.6	0.4	1.2	-0.1	0.3	1.3	-0.4	-0.5	-0.6	0.9	0.2	-0.1	-0.5
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	2.8	4.0	8.9	-2.6	-0.8	3.0	2.5	-2.9	1.6	0.3	2.1	-0.6	-1.0	-2.5	1.4
Bipolar Disorder (2011)	2.7	2.7	7.6	0.1	-0.9	1.8	2.2	-1.7	-2.0	-2.8	1.0	-0.8	0.1	-1.9	-1.9
Body Mass Index (BMI) (2010)	0.2	0.3	0.9	0.9	-0.0	-0.1	0.2	0.9	-0.5	-0.7	0.1	-0.7	0.8	0.2	-0.6
Coronary Artery Disease (CAD)	1.1	1.3	2.8	-0.7	-1.6	-1.5	-1.6	0.1	0.1	0.5	1.7	0.3	-1.1	1.4	-1.2
Crohns Disease (2012)	1.1	1.8	4.6	0.4	-0.9	-2.0	-1.6	0.4	-1.5	-0.7	-1.8	0.0	1.8	2.2	-0.1
Mean Putamen Volume	0.8	0.9	3.2	-0.2	-1.8	-0.6	-0.6	0.3	0.5	1.2	-0.4	1.4	0.4	0.7	1.4
Fasting Glucose	1.1	1.3	5.0	-0.8	0.1	-0.1	-0.5	0.0	2.2	2.0	1.1	0.5	0.0	0.6	2.0
HbA1C	0.6	0.6	4.6	0.3	-2.1	0.2	-0.1	-0.6	0.8	0.6	0.4	1.0	0.1	0.0	0.4
HDL Cholesterol	0.2	0.4	3.4	-0.5	-0.4	-0.2	0.7	0.3	0.2	-1.8	0.1	0.2	-0.0	-0.1	0.4
LDL Cholesterol	0.3	0.5	1.7	1.0	-0.4	0.0	0.2	-0.6	-1.2	-1.1	-0.5	-0.2	0.0	-0.2	-1.3
Lupus	0.4	0.6	1.6	0.7	-1.1	-0.8	-0.9	-0.5	-0.8	-0.4	0.1	0.4	0.6	0.8	-1.3
Neuroticism (2016)	0.2	0.3	1.4	0.4	0.3	-0.0	-0.4	-0.2	-0.5	1.2	-0.3	-0.5	-0.7	0.2	-0.9
Primary Biliary Cirrhosis	1.4	2.0	4.5	1.3	-1.0	-2.0	-1.5	1.6	-0.6	-1.6	-0.8	0.8	2.1	1.8	-0.7
Rheumatoid Arthritis	0.4	0.5	3.2	0.6	0.4	-0.5	-0.5	0.6	-0.8	-0.2	-0.7	-0.6	-0.3	0.4	-1.8
Schizophrenia (2014)	0.3	0.8	2.0	-0.5	-1.0	0.7	0.8	-0.8	0.2	-0.6	1.4	-1.1	-1.4	-0.6	-0.4
Triglycerides	0.8	1.3	4.4	0.5	-1.1	-0.0	-0.1	1.1	-1.4	1.2	1.0	-2.1	-1.4	-0.1	-1.4
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.5	-1.6	-0.3	-0.4	0.3	0.6	-0.5	0.7	1.2	-1.0	0.6	0.7	0.4
Ulcerative Colitis	0.5	0.7	1.9	-0.1	1.4	-0.5	-1.3	0.1	1.1	1.2	-1.1	-0.0	-0.4	0.8	0.2
Blood Eosinophil Count	0.2	1.6	3.8	0.7	0.8	-1.7	-1.4	1.7	-0.5	-0.4	-1.8	0.0	2.0	1.6	-0.2
Blood Platelet Count	0.7	8.0	36.1	3.8	-0.2	-0.9	0.3	0.0	-2.0	-3.3	-3.9	3.3	6.0	0.9	1.6
Blood Red Count	0.8	7.5	12.8	3.6	1.6	-2.7	-1.9	3.0	-2.4	-3.6	-3.5	2.8	2.7	2.9	-1.1
Blood White Count	2.4	18.1	35.3	5.1	2.4	-4.5	-2.6	4.3	-5.1	-4.6	-5.9	2.1	5.8	4.1	-1.6
Heel T-Score	1.9	15.3	32.1	5.2	2.9	-4.3	-4.7	1.4	-3.7	-1.4	-4.3	4.1	5.7	4.9	-0.7
BMI	0.3	1.6	5.2	-0.6	0.3	-1.5	-1.9	1.5	0.8	2.3	0.3	-0.6	0.3	1.6	0.9
Height	3.1	59.2	179.6	-10.9	0.6	7.3	6.1	-3.8	6.6	6.3	9.4	-8.1	-13.4	-8.3	-0.6
Waist Hip Ratio (WHR)	0.8	3.4	9.0	-2.0	-0.4	2.4	1.8	-1.4	1.1	1.7	1.7	-1.9	-3.0	-2.4	1.0
Systolic Blood Pressure	1.1	5.5	11.5	2.0	-0.4	-3.4	-2.9	2.3	-0.8	-0.9	-2.7	2.8	3.1	3.3	0.8
Smoking Status	2.5	6.0	11.8	-1.6	1.4	3.4	2.8	-2.4	1.7	1.2	3.1	-2.7	-3.0	-3.4	0.6
Allergy or Eczema	0.7	1.8	10.6	0.3	1.8	-0.0	0.4	1.1	-1.1	-1.6	-3.2	0.6	1.5	-0.1	-0.1
Cardiovascular Disease	0.1	0.4	1.1	0.7	0.1	-1.0	-0.7	1.0	0.7	-0.3	-0.1	-0.3	0.7	0.6	-0.5
Hypothyroidism (self reported)	1.6	3.7	7.6	2.8	-1.1	-2.6	-2.5	2.3	-1.8	-0.2	-1.6	1.6	1.3	2.6	-0.9
Respiratory disease	1.6	3.5	9.4	1.7	0.5	-2.6	-2.1	1.6	-1.5	-1.1	-3.1	0.7	2.4	2.3	-0.9
Type 2 Diabetes (T2D) (2018)	0.7	1.2	2.8	-0.1	1.0	-1.5	-1.4	1.2	0.3	1.5	-0.3	-0.3	0.6	1.5	1.7
Lung FEV1/FVC ratio	0.3	1.5	5.1	-0.4	1.1	-1.3	-1.3	0.8	0.3	0.3	2.2	-1.8	0.3	1.1	-1.6
Lung FVC	5.3	27.1	50.9	-5.6	-2.0	7.1	6.5	-5.7	3.9	2.0	5.3	-5.0	-6.2	-7.1	1.5
Neuroticism	0.2	0.5	1.3	1.1	0.8	1.2	0.7	-0.6	-0.0	-0.3	-0.6	0.3	-0.3	-1.0	-0.4
Chronotype (morning person)	0.3	0.6	2.0	1.2	-0.3	0.7	0.6	-0.7	0.3	-0.8	0.4	0.7	1.4	-0.8	0.4
Hair Pigment	1.2	34.1	225.0	5.3	2.4	-1.5	-0.2	4.6	-7.2	-5.5	-15.0	2.4	6.0	1.5	-0.6
Tanning	0.1	1.5	4.5	0.9	0.2	1.3	2.0	-1.2	-0.4	-2.1	1.4	-0.4	0.3	-1.5	-1.1
Hand grip strength (left)	2.2	5.8	11.6	-3.0	-1.1	3.0	2.8	-2.6	2.9	0.8	2.2	-1.4	-2.9	-3.4	0.2
Number of treatments/medications taken	0.5	1.0	5.2	0.1	2.3	-0.7	-0.7	1.2	0.2	0.4	-0.3	-1.2	1.2	0.6	0.4
Average weekly spirits intake	2.9	3.6	7.5	2.0	1.2	-2.7	-2.0	2.1	-1.3	-1.2	-2.1	1.9	1.8	2.7	0.2
Sensitivity / hurt feelings	1.5	2.6	9.5	2.4	-0.6	-1.1	-0.6	1.2	-3.1	-2.0	-1.4	-0.2	1.2	1.1	-1.9
Frequency of depressed mood in last 2 weeks	1.0	1.4	4.6	0.7	-0.7	1.2	0.5	-0.3	-0.8	0.2	1.2	-1.9	-1.5	-1.3	-2.1
Hearing difficulty/problems: Yes	2.5	3.8	6.7	-0.5	-1.0	2.6	2.2	-2.2	2.1	2.1	2.5	-0.5	-1.2	-2.3	2.5
Relative age of first facial hair	0.5	1.0	4.3	-1.0	1.4	1.0	0.1	-0.3	1.0	1.4	0.8	-0.1	-2.1	-0.7	-0.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.8	0.7	-0.2	-0.4	-1.2	0.8	-0.8	1.4	-0.5	-0.8	-0.3	0.5	-0.9
Ever used hormone-replacement therapy (HRT)	3.0	3.9	8.5	1.7	1.0	-2.2	-2.5	1.5	-0.2	0.5	-2.5	2.5	2.9	2.5	1.3
Ever had hysterectomy (womb removed)	0.2	0.2	0.6	0.3	0.1	0.7	0.2	-0.4	0.4	0.8	0.5	-0.5	0.3	-0.8	0.0
Systolic blood pressure, automated reading	1.3	3.6	6.7	2.1	0.8	-2.5	-2.3	1.6	-0.7	-0.4	-2.6	1.8	2.6	2.6	1.0
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	5.0	-0.7	1.5	0.4	0.5	-0.0	1.7	0.6	0.8	1.2	0.7	-0.3	2.2
Angina	1.4	1.8	5.5	-2.3	-0.8	0.1	-0.4	-0.4	1.5	2.1	1.6	-1.8	-1.6	-0.4	-0.2
Medication for hormone replacement therapy	0.8	0.9	4.6	-0.2	0.2	0.7	0.8	-0.9	1.0	0.5	-0.3	1.3	0.7	-0.4	2.2
Vitamin and mineral supplements	0.6	0.8	2.2	-0.5	-0.8	0.8	0.9	-1.1	-0.2	-0.9	0.6	-0.4	-1.5	-0.8	-1.3
Supplements: Zinc	0.9	0.9	6.9	-0.2	2.6	-0.3	-0.3	0.1	-0.0	0.1	-1.2	-0.9	1.2	0.3	0.4
Medication: Co-codamol	1.0	1.2	7.8	-0.6	-0.6	0.3	0.5	0.1	-0.7	0.1	0.4	-2.8	-1.4	-0.6	-1.4
Medication: Metformin	0.5	0.6	3.6	-0.4	0.8	-0.2	-0.2	0.0	-0.0	1.3	-0.2	-0.4	1.1	0.3	1.9
Diabetes (father)	1.2	1.5	3.7	-1.0	-0.4	1.0	0.4	-1.0	1.4	1.9	1.9	-0.5	-1.8	-1.0	1.2
Diabetes (mother)	2.0	2.6	8.7	-2.0	0.5	1.3	0.7	-1.0	2.1	1.5	2.3	-0.9	-3.0	-1.3	0.1
Severe depression (siblings)	1.2	1.3	7.4	-0.6	-2.7	1.2	1.0	-1.0	-0.0	0.5	1.2	-0.8	-0.8	-1.3	-0.5
Pack years adult smoking proportion	4.0	6.1	13.4	-2.7	-0.4	3.3	3.6	-2.0	1.6	-0.4	3.4	-1.9	-2.5	-3.7	-0.3
Impedance of leg (right)	0.4	2.1	4.4	2.1	-0.4	-1.8	-1.9	1.4	-0.1	-0.3	-1.4	2.1	1.2	2.0	-0.0
Leg fat-free mass (left)	1.5	7.8	20.5	-4.1	0.1	2.6	2.2	-1.3	2.1	2.6	3.5	-3.3	-4.5	-3.0	-0.0
Trunk fat percentage	0.7	2.9	10.9	-1.9	0.6	-1.2	-1.9	1.7	2.4	3.3	0.8	0.3	-1.3	1.2	1.7
Hand grip strength (right)	3.3	8.9	20.1	-3.9	-0.5	3.2	2.7	-2.5	3.5	2.1	3.0	-3.1	-4.5	-3.6	0.0
Townsend deprivation index at recruitment	1.2	1.7	3.6	-1.4	0.6	1.4	0.9	-0.6	1.8	1.4	1.9	-0.8	-1.7	-1.6	0.1
Current tobacco smoking	3.7	6.0	13.1	-2.2	0.2	3.3	3.4	-3.2	0.7	0.4	2.7	-2.6	-2.5	-3.6	0.4
Average weekly fortified wine intake	0.4	0.5	3.0	0.2	0.2	-0.0	-0.4	-0.8	0.9	0.0	-0.5	1.7	-0.1	0.2	0.6
Maternal smoking around birth	1.2	1.8	6.9	-0.4	0.2	1.7	1.1	-0.7	2.6	0.3	0.9	2.1	-0.3	-1.3	1.5
Fed-up feelings	0.8	1.4	4.3	1.8	0.9	-1.1	-1.4	2.1	-0.3	-0.1	-1.2	1.1	1.0	1.3	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	1.4	-0.1	-1.2	1.0	0.6	-1.1	-0.2	0.4	1.1	-0.8	-1.2	-0.9	-0.5
Relative age voice broke	0.6	0.9	4.0	-0.4	0.5	-0.5	-1.2	0.5	1.2	2.0	0.5	-0.5	-1.3	0.6	-0.1
Taking other prescription medications	0.4	0.5	2.9	0.5	1.7	-0.3	-0.5	0.7	0.4	0.1	-0.6	-0.9	-0.1	0.1	-1.2
Age when periods started (menarche)	0.1	0.3	0.9	0.7	0.2	0.3	0.7	-0.0	-0.8	-1.0	0.6	-0.4	0.7	-0.3	-0.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	3.9	-0.2	2.0	0.1	0.0	-0.1	-0.3	0.6	-0.5	-0.4	0.1	-0.2	0.3
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	9.4	1.9	1.4	-2.5	-3.1	1.3	-0.5	1.3	-1.8	1.6	1.4	2.6	-0.3
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	2.4	-1.4	1.1	0.4	0.5	0.4	1.5	-0.1	0.8	-0.4	-0.7	-0.6	0.2
Qualifications: CSEs or equivalent	0.4	0.5	1.6	0.5	-1.3	-0.4	-0.6	0.3	-0.2	0.3	0.7	-1.0	-0.6	0.2	-1.1
Serious illness, injury or assault to yourself	0.7	0.9	2.9	-0.1	-0.1	-0.7	-1.2	0.3	0.9	1.4	-0.3	-0.7	-1.7	0.4	-1.3
High blood pressure	0.2	0.5	3.7	0.9	0.1	-0.1	-0.0	-0.1	-0.1	-0.0	-0.6	-0.3	1.9	0.1	1.1
Hayfever, allergic rhinitis or eczema	0.3	0.7	4.3	-0.2	1.4	0.4	0.4	1.0	-0.6	-0.5	-2.1	0.0	0.9	-0.2	0.3
Multivitamins +/- minerals	0.4	0.5	1.3	0.6	0.6	-0.6	-0.7	1.1	-0.3	0.7	-0.2	0.4	1.1	0.8	0.6
Stomach or abdominal pain in last month	0.5	0.6	3.0	0.6	1.1	-0.4	-0.6	0.9	-0.5	-0.3	-0.8	-0.0	-0.4	0.1	-1.7
Supplements: Glucosamine	0.3	0.4	1.9	0.1	-0.4	0.6	0.3	-1.1	0.4	0.4	-0.2	0.5	1.4	-0.2	0.9
Diverticular disease/diverticulitis (self-reported)	2.7	3.2	13.9	3.7	2.9	-0.5	-1.1	0.8	-1.7	0.0	-2.5	1.7	1.0	0.7	-0.8
Medication: Atenolol	1.1	1.4	5.8	-1.5	0.7	0.7	0.6	-0.2	1.1	1.5	1.2	-2.4	-0.8	-1.0	0.9
Medication: Levothyroxine sodium	1.9	3.2	7.2	2.3	-0.2	-2.4	-2.3	2.7	-1.5	-0.4	-1.3	1.5	0.5	2.5	-1.2
Sitting height	2.9	20.4	59.0	-5.8	-0.2	4.6	4.1	-2.3	3.2	3.3	5.7	-5.3	-7.7	-5.2	-0.3
Chronic bronchitis/emphysema (father)	0.2	0.2	0.7	-0.0	-0.8	-0.5	-0.2	0.8	-0.5	-0.1	0.2	0.2	-0.1	0.4	0.4
High blood pressure (mother)	1.1	1.5	4.7	-0.3	2.2	-1.6	-2.0	0.6	-0.0	1.6	0.4	0.1	-0.7	1.7	-0.6
Body mass index (BMI)	0.4	1.5	4.2	-0.7	0.4	-1.8	-2.0	1.6	0.5	2.0	-0.0	-0.1	0.4	1.8	0.6
Impedance of leg (left)	0.4	1.7	4.3	1.4	-0.0	-1.9	-2.1	1.7	0.2	0.1	-0.9	1.5	0.6	2.0	-0.2
Leg predicted mass (left)	1.5	8.0	20.3	-4.2	-0.0	2.7	2.3	-1.4	2.1	2.5	3.5	-3.3	-4.5	-3.1	-0.1
Trunk fat mass	0.8	3.3	12.5	-2.8	0.7	-0.4	-1.0	1.1	2.5	3.5	1.7	-0.8	-2.3	0.2	1.4
Waist circumference	0.5	1.7	8.4	-1.7	0.5	-0.3	-1.1	0.3	1.4	2.9	1.1	-1.0	-1.6	0.2	0.8
Number of incorrect matches in round	5.1	8.4	22.8	-3.9	0.7	1.8	1.5	-2.1	0.9	2.6	4.8	-4.7	-4.1	-2.1	-1.2
Past tobacco smoking	0.6	1.1	3.1	0.4	0.0	-1.5	-1.8	0.2	-0.9	0.5	-1.7	0.7	0.9	1.4	-1.0
Alcohol usually taken with meals	1.8	2.9	9.5	1.8	0.2	-1.1	-0.9	-0.2	-1.5	-1.4	-2.3	3.1	2.7	1.5	0.7
Nervous feelings	0.1	0.3	0.8	0.4	0.1	0.6	0.5	0.1	0.6	-0.2	-0.7	0.9	-0.1	-0.3	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.5	5.5	0.9	0.2	-0.8	-1.0	1.4	-1.7	-0.2	-0.8	-1.8	-0.2	0.6	-2.3
Hearing difficulty/problems with background noise	1.3	2.1	5.2	-0.4	-1.1	1.6	1.0	-1.5	2.3	1.8	1.8	0.2	-1.0	-1.3	1.8
Hair/balding pattern: Pattern 2	0.8	1.0	5.2	0.1	-0.7	0.5	0.2	-0.0	0.9	0.5	-0.4	2.1	0.3	-0.1	2.3
Had menopause	0.8	0.9	2.9	0.9	1.2	-0.5	-1.1	0.3	0.3	1.4	-1.7	0.3	1.0	0.8	0.9
Had other major operations	0.8	1.0	5.4	-0.6	-0.1	1.2	0.8	-2.3	0.6	-0.3	0.1	1.1	1.0	-1.1	0.2
Forced vital capacity (FVC)	6.5	25.0	57.6	-5.3	-1.8	6.5	5.4	-5.0	3.9	2.4	5.5	-4.5	-7.6	-6.7	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	2.7	6.1	15.1	2.7	0.3	-3.5	-3.9	1.9	-1.1	0.6	-2.6	2.8	2.3	3.7	-0.3
Ever unenthusiastic/disinterested for a whole week	0.5	0.7	2.5	0.8	-0.3	0.9	0.6	-1.3	0.0	-0.8	-0.7	1.6	0.4	-0.8	0.2
Qualifications: None of the above	0.3	0.6	2.2	-0.1	-0.8	-0.3	-0.2	1.5	0.9	-0.0	0.2	-1.1	-1.0	-0.1	-1.1
Financial difficulties in last 2 years	0.5	0.7	3.8	0.6	0.4	-0.5	-0.6	0.7	-0.5	-0.0	0.7	-0.5	-1.2	0.1	-2.0
Mouth/teeth dental problems	3.4	5.2	16.0	2.8	1.4	-2.2	-2.0	1.0	-4.0	-1.6	-3.3	1.2	2.2	2.2	-1.4
Heart attack	1.3	1.7	6.8	-2.6	0.5	-0.3	-0.5	-0.3	2.1	1.4	1.1	-1.8	-1.3	-0.3	-0.2
Allergy	0.3	0.8	4.5	0.4	-1.7	0.3	0.3	-0.4	0.2	0.4	2.1	0.3	-0.9	-0.1	0.1
Pain all over the body in last month	2.4	2.6	9.3	-1.9	-0.9	0.0	0.3	0.7	1.0	2.0	3.1	-2.4	-2.5	-0.3	-0.3
Diabetes (self-reported)	0.4	0.6	3.0	-0.4	0.8	-0.3	-0.5	-0.2	0.4	1.7	0.4	-0.8	-0.1	0.4	1.4
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	2.4	-1.6	0.6	1.1	1.4	0.0	1.6	-0.6	-0.4	-0.4	-0.6	-1.4	0.3
Medication: Ramipril	0.6	0.8	2.2	-1.1	-0.0	-0.3	-0.8	-0.1	1.5	1.5	1.1	-0.0	0.2	0.5	1.4
Medication: Simvastatin	0.9	1.4	3.1	-1.6	1.7	0.3	0.3	0.2	1.7	1.1	0.5	-1.7	-1.8	-0.7	-0.0
Fluid intelligence score	0.9	1.8	7.4	1.5	-0.8	-0.1	0.0	-0.1	0.0	-1.1	-1.1	2.7	2.6	0.4	1.5
Illnesses of siblings	0.6	0.9	3.8	-0.3	-0.0	1.1	0.9	-0.8	-0.1	0.1	-0.1	-0.4	-1.9	-1.2	-1.6
Neuroticism score	0.3	0.6	2.9	1.7	-0.7	0.4	-0.1	0.3	-0.0	-0.5	-1.2	1.2	0.5	-0.1	0.1
Weight	0.8	4.0	10.9	-3.2	0.4	0.5	-0.0	0.3	1.9	3.2	2.5	-2.3	-3.3	-0.8	0.3
Impedance of arm (right)	0.2	0.8	4.2	0.7	-0.5	0.9	1.0	-0.0	0.6	-0.6	0.1	2.1	-0.5	-0.8	1.0
Arm fat percentage (right)	0.3	1.3	3.8	-1.0	0.1	-1.3	-1.6	1.5	0.9	1.9	0.3	0.6	0.1	1.3	1.2
Trunk fat-free mass	1.5	8.4	21.8	-4.2	0.2	2.5	2.3	-1.4	1.6	2.2	3.5	-4.2	-4.7	-3.0	-0.9
Hip circumference	0.4	1.7	8.5	-1.4	-0.1	-0.9	-1.6	0.6	1.2	2.9	1.2	-0.2	-1.4	0.8	0.5
Time employed in main current job	0.4	0.5	2.4	-0.3	-0.1	0.4	1.0	-0.4	-0.6	-0.3	0.3	1.6	-0.7	-0.2	1.0
Alcohol intake versus 10 years previously	0.4	0.6	2.6	-0.9	1.1	0.6	-0.0	0.1	0.9	1.6	0.1	-0.4	-0.5	-0.6	0.7
Father’s age at death	1.4	1.9	6.1	-1.4	-0.4	2.0	1.8	-2.5	0.4	0.2	1.1	-0.3	-0.1	-1.6	1.6
Worrier / anxious feelings	0.5	0.9	3.6	1.5	0.3	-0.5	-0.6	1.6	-0.1	-0.4	-1.9	0.9	0.0	0.5	-0.5
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	8.1	1.4	1.8	-0.7	-1.0	0.8	-0.6	-0.2	-0.9	-0.4	-1.5	0.3	-2.8
Falls in the last year	0.7	0.9	2.2	-0.4	0.2	1.1	1.2	-0.2	1.3	-0.3	1.5	-1.3	-0.3	-1.3	-0.5
Hair/balding pattern: Pattern 3	0.6	0.8	2.9	-1.2	0.1	0.2	0.4	-1.4	0.7	0.8	1.5	-1.7	0.1	-0.5	0.3
Number of live births	0.2	0.3	1.3	1.1	0.2	-0.4	-0.5	0.7	-1.0	0.4	-0.1	-0.3	0.3	0.2	-0.4
Forced expiratory volume in 1-second (FEV1)	5.2	17.7	40.3	-4.6	-1.4	5.1	4.4	-3.9	3.1	1.6	5.2	-4.5	-6.3	-5.3	-1.3
Pulse rate	0.2	0.4	1.3	-0.4	-0.0	0.2	0.1	0.1	-1.1	-0.4	-0.3	-0.9	-1.1	-0.3	-0.9
Happiness	0.7	0.8	2.0	-0.7	0.0	-0.5	-1.3	1.4	0.7	1.4	0.6	-0.3	-1.0	0.6	-1.0
Noisy workplace	0.4	0.5	1.8	-0.1	1.1	-0.5	0.0	0.9	-0.2	-1.3	-0.7	-0.7	0.4	0.3	-0.7
Qualifications: A levels/AS levels or equivalent	1.1	2.4	6.5	-1.0	-0.0	2.3	1.8	-2.5	0.5	1.2	1.1	0.5	-0.6	-1.7	2.5
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	1.1	0.3	-0.6	-0.8	-0.3	1.0	-1.0	-1.0	-0.6	0.9	0.2	0.6	-0.1
Mouth/teeth dental problems: Dentures	1.7	2.9	9.3	-2.3	0.8	1.2	0.8	-0.9	3.1	2.2	2.1	-1.1	-1.6	-1.3	1.3
Asthma	1.1	2.1	5.9	0.9	1.5	-1.6	-1.5	0.4	-1.2	-0.6	-2.4	1.0	2.4	1.6	0.2
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	2.0	-0.1	1.0	0.3	0.2	-0.4	0.3	0.6	0.4	1.4	0.3	-0.1	1.1
Medication: Cholesterol lowering	0.4	0.6	2.1	-1.4	0.7	-0.0	0.1	0.3	0.9	0.5	0.6	-1.3	-1.1	-0.3	-0.4
Depression (self-reported)	0.7	0.8	2.1	1.2	1.5	-0.9	-1.4	0.4	0.3	0.1	-0.9	0.7	0.2	1.0	-1.1
Medication: Lansoprazole	0.5	0.5	1.4	0.6	0.9	0.8	1.2	-0.0	-0.4	-0.8	-0.0	0.0	1.1	-0.7	0.9
Prospective memory result	0.6	0.8	2.2	-1.1	0.7	0.8	1.1	-0.2	0.5	-0.2	1.5	-1.1	-1.1	-0.9	0.2
Lung cancer (father)	1.2	1.5	5.0	1.9	1.3	-0.8	-0.6	1.0	-1.3	-0.7	-1.1	0.3	2.2	1.0	0.8
Illnesses of mother	1.0	1.3	3.8	1.9	-1.2	0.0	0.2	0.1	-0.4	-2.0	-1.8	1.4	0.6	-0.0	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	4.6	14.7	31.1	-3.6	-1.9	4.8	4.2	-4.1	2.4	0.9	5.0	-3.6	-5.6	-4.9	-1.2
Pulse wave Arterial Stiffness index	0.9	1.1	5.0	-1.0	1.2	1.0	1.1	-0.1	0.8	-0.2	-0.9	0.6	0.9	-0.7	2.2
Impedance of arm (left)	0.3	1.2	3.8	-0.1	-0.3	1.1	1.1	-0.6	1.5	0.1	0.6	1.9	-0.8	-1.0	1.8
Arm fat mass (right)	0.5	2.1	8.1	-2.4	0.2	-0.6	-1.0	1.1	1.6	2.9	1.4	-1.0	-1.5	0.5	0.9
Trunk predicted mass	1.5	8.3	22.5	-4.2	0.2	2.5	2.2	-1.4	1.6	2.2	3.4	-4.1	-4.7	-3.0	-0.9
Standing height	2.1	20.9	66.7	-5.7	0.0	4.8	4.2	-2.3	3.5	3.2	5.7	-4.7	-8.2	-5.4	-0.7
Length of working week for main job	0.7	0.8	4.9	-0.1	0.6	-0.9	-0.7	2.2	-0.4	-0.2	-1.5	-0.1	0.1	0.7	-0.1
Exposure to tobacco smoke at home	0.4	0.5	1.7	-0.2	1.1	0.6	0.3	0.4	0.6	0.9	1.3	-0.5	-0.5	-0.5	0.1
Breastfed as a baby	0.5	0.7	2.2	-0.5	1.2	0.2	-0.1	-1.0	0.5	0.9	0.8	1.0	-0.3	0.2	1.5
Tense / ‘highly strung’	0.4	0.6	1.8	-0.4	-1.1	1.2	1.4	-0.0	0.3	-0.6	0.2	-1.1	-0.1	-1.1	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	5.0	1.9	-0.6	0.1	0.8	0.0	0.0	-2.2	-0.8	0.9	1.3	-0.0	-0.0
Hair/balding pattern: Pattern 4	0.5	1.1	2.8	0.4	1.7	-0.7	-0.4	1.7	-1.7	-0.7	-0.8	-1.2	0.4	0.5	-1.0
Birth weight of first child	0.8	1.5	3.4	-1.5	0.6	1.3	1.4	-1.8	1.2	-0.1	1.1	-0.6	-1.8	-1.5	-0.5
Peak expiratory flow (PEF)	3.5	8.2	23.6	-4.2	-2.3	1.9	2.1	-1.2	2.2	1.3	4.9	-3.7	-4.0	-2.3	-1.0
Pulse wave reflection index	0.8	1.0	5.5	-0.3	0.8	-0.2	0.3	0.6	1.0	-0.8	-1.1	0.6	2.3	0.3	1.4
Ever highly irritable/argumentative for 2 days	1.1	1.3	4.3	0.0	2.1	1.4	0.8	-1.4	-0.4	-0.8	-0.3	-0.6	-0.4	-1.6	-1.5
Loud music exposure frequency	1.8	2.0	4.8	1.3	-0.9	1.5	1.3	-1.3	-0.5	-2.1	-1.4	-0.9	0.3	-1.7	-2.2
Qualifications: O levels/GCSEs or equivalent	0.5	0.9	2.1	0.0	-0.6	1.4	1.1	-1.4	-0.7	0.6	1.1	0.2	0.3	-0.9	1.2
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	3.3	0.3	-0.1	-1.7	-1.8	1.8	1.0	1.0	-0.6	1.5	-0.8	1.5	0.1
Blood clot in the leg (DVT)	2.9	3.7	9.5	-2.4	1.5	1.8	1.4	-2.1	1.6	0.8	2.0	-3.1	-1.8	-2.1	-1.3
Medication: Paracetamol	0.5	0.9	2.5	1.3	0.4	-0.6	-0.1	1.6	-0.6	-1.2	-0.9	0.7	1.5	0.7	0.0
Headache pain in last month	0.2	0.4	2.5	-0.5	0.4	0.7	0.2	0.1	1.6	0.6	0.2	0.3	-0.1	-0.7	0.0
Medication for cholesterol, blood pressure or diabetes	0.0	0.1	0.2	0.2	0.4	0.4	0.2	-0.4	-0.2	-0.1	0.1	0.1	0.0	-0.1	-0.2
Glaucoma (self-reported)	1.4	1.7	5.5	2.1	0.6	-0.4	-0.2	0.8	-1.1	-1.8	-2.4	1.0	1.9	0.3	0.0
Gout (self-reported)	1.0	1.3	2.9	1.6	-0.4	-1.7	-1.4	1.5	-0.7	-0.4	-1.6	0.8	-0.1	1.4	-0.8
Hypothyroidism/myxoedema (self-reported)	2.4	4.7	9.9	3.1	-0.1	-2.7	-2.4	2.5	-2.0	-0.8	-2.1	2.5	1.8	2.8	-0.5
Medication: Amlodipine	0.8	1.2	3.3	0.6	-1.8	0.8	1.2	-1.8	0.7	-1.3	1.0	-0.2	0.4	-1.1	-0.8
Medication: Ventolin 100micrograms inhaler	0.6	0.7	1.3	0.7	0.8	-1.1	-1.1	-0.1	-0.8	-0.7	-1.0	-0.1	1.0	0.9	-0.9
Birth weight	3.3	7.2	19.9	-2.5	0.2	3.1	2.9	-1.3	-0.4	-0.5	2.2	-3.9	-4.5	-3.6	-2.7
Chronic bronchitis/emphysema (mother)	1.3	1.5	4.5	1.4	0.8	-0.2	0.2	1.0	-1.1	-2.1	-1.0	1.6	1.9	0.3	-1.1
High blood pressure (siblings)	0.7	1.0	4.7	-0.4	-0.6	-0.6	-0.1	0.8	-0.2	-0.3	0.7	0.5	2.0	0.8	2.2
Forced vital capacity (FVC), Best measure	5.7	20.7	47.7	-4.4	-1.9	5.9	5.3	-5.0	2.8	1.3	5.1	-4.0	-6.9	-6.2	-0.8
Body fat percentage	0.7	2.6	8.5	-1.3	0.6	-1.7	-2.3	1.9	1.7	2.9	0.4	0.5	-0.3	1.7	1.6
Leg fat percentage (right)	1.0	3.5	9.9	0.1	0.4	-2.7	-3.1	2.3	0.7	2.5	-0.5	1.0	1.2	2.9	1.3
Arm fat-free mass (right)	1.2	5.9	16.8	-3.8	0.8	1.0	0.6	-0.2	1.7	2.9	2.6	-4.1	-4.1	-1.6	-0.8
Exposure to tobacco smoke outside home	0.7	1.0	2.8	-1.2	0.7	0.4	0.6	1.7	1.3	0.5	0.5	-1.4	-1.3	-0.8	0.2
Comparative body size at age 10	0.5	1.5	4.4	1.1	-2.1	-0.9	-0.9	-0.2	-2.0	-0.2	0.5	-1.0	-0.5	0.7	-2.0
Number of full brothers	1.1	1.4	6.2	-1.0	-0.9	0.9	0.5	-0.7	1.7	1.2	2.5	-0.1	-1.2	-0.9	0.5
Worry too long after embarrassment	0.2	0.3	1.4	0.9	-0.6	0.0	0.0	0.4	-0.1	-0.8	-1.2	0.3	0.6	0.1	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.7	1.6	-0.5	-1.0	-0.9	0.8	-0.4	-0.1	-1.1	0.9	0.8	1.2	0.8
Wheeze or whistling in the chest in last year	0.3	0.6	2.7	-0.9	1.6	0.7	0.3	-0.7	0.2	0.0	-0.5	-1.2	0.2	-0.9	-0.3
Number of children fathered	0.3	0.3	1.2	0.3	-0.5	-0.7	-0.8	-0.4	1.1	0.6	-0.2	0.0	0.4	0.6	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	2.3	0.1	-0.4	0.1	0.5	-0.9	-1.5	-0.8	0.0	-0.5	0.3	0.1	-0.5
Age at first live birth	0.9	1.7	8.6	-0.3	-0.8	2.0	1.4	-2.9	-0.4	-0.8	0.2	0.7	-0.5	-1.8	-0.3
Pulse wave peak to peak time	1.0	1.2	5.7	0.6	-1.3	-0.7	-0.8	0.0	-0.7	0.3	1.2	-1.0	-1.5	0.4	-2.4
Health satisfaction	1.3	1.6	5.2	1.3	0.2	-1.6	-1.7	1.4	-1.0	-0.5	-1.2	1.0	-0.6	1.2	-2.3
Shortness of breath walking on level ground	0.6	0.7	3.0	0.9	0.7	-0.5	-0.7	0.5	-1.0	-0.6	-1.4	-0.1	0.4	0.3	-1.7
Qualifications: College or University degree	0.4	1.4	9.4	0.5	-0.6	0.3	0.0	0.1	0.2	0.4	-1.1	3.1	0.8	0.3	2.2
Eye problems/disorders: None of the above	1.8	2.1	6.9	-1.5	-1.8	0.1	-0.7	-1.0	1.3	1.7	1.0	-1.4	-2.6	-0.2	-1.8
Mouth/teeth dental problems: Loose teeth	1.5	1.8	3.9	-1.0	-1.3	1.9	1.9	-1.5	0.2	0.1	1.7	-0.8	-1.4	-2.0	0.1
Emphysema/chronic bronchitis	1.4	1.6	3.7	-1.7	0.2	1.4	1.2	-1.8	0.8	0.6	1.2	-0.9	-1.9	-1.5	-0.6
Medication for pain relief, constipation, heartburn	0.6	1.0	3.3	0.6	-1.8	-0.1	0.1	-1.3	-1.7	-1.1	-0.0	-0.1	-0.2	0.0	-1.4
Neck or shoulder pain in last month	0.8	1.1	2.4	0.8	1.1	-1.5	-1.5	1.0	-0.2	-0.4	-1.4	0.3	1.0	1.3	-1.1
Medication: Blood pressure	0.2	0.4	2.5	-0.3	-0.7	-0.1	-0.3	-0.2	0.4	1.1	0.1	0.6	0.3	0.1	1.6
Angina (self-reported)	1.6	2.1	6.6	-2.6	-0.7	0.3	-0.2	-0.7	1.7	2.1	1.7	-2.0	-1.7	-0.6	-0.4
Migraine (self-reported)	0.4	0.5	3.1	-0.2	-0.3	0.2	-0.1	0.1	0.9	1.7	-0.2	0.1	-0.1	-0.2	1.3
Medication: Ibuprofen	0.4	0.5	1.9	-0.3	0.5	-0.3	-0.4	0.2	0.1	0.8	0.3	1.4	0.6	0.6	1.4
Medication: Allopurinol	0.1	0.1	0.7	0.4	-0.3	-0.2	-0.0	0.4	-0.0	0.1	-0.9	-0.3	-0.2	0.1	0.3
Medication: Omeprazole	1.0	1.2	3.6	1.4	0.4	-1.1	-0.5	1.6	-0.8	-1.7	-0.5	-0.0	1.9	1.2	-0.2
Medication: Seretide 50 evohaler	0.3	0.4	0.9	-0.2	1.0	0.6	1.0	-0.6	0.5	-0.7	-0.0	-0.7	0.1	-0.8	-0.2
Mean time to correctly identify matches	1.2	2.3	5.3	1.3	1.3	-1.7	-1.3	1.9	-0.6	-0.9	-2.0	2.3	1.5	1.8	0.0
Heart disease (mother)	0.6	0.7	2.4	0.5	-1.1	0.2	-0.6	-1.3	-0.0	1.5	0.5	0.1	1.2	0.0	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.8	0.6	0.4	-1.0	-1.1	1.0	-0.7	0.1	-0.1	-1.3	1.0	1.2	-1.1
Whole body fat mass	0.7	3.1	12.2	-2.6	0.5	-0.6	-1.2	1.1	2.2	3.5	1.7	-0.9	-2.1	0.5	1.3
Leg fat mass (right)	0.5	1.8	8.1	-1.5	0.7	-1.1	-1.6	1.4	1.3	2.8	1.0	-0.4	-1.0	1.0	1.0
Arm predicted mass (right)	1.2	6.1	17.1	-3.9	0.7	1.2	0.8	-0.4	1.8	2.9	2.7	-4.1	-4.1	-1.7	-0.7
Pulse rate, automated reading	0.4	1.3	4.6	0.5	2.1	0.2	0.4	1.1	-1.6	-1.5	-0.5	-1.6	0.4	-0.3	-1.0
Alcohol intake frequency.	0.4	0.9	2.5	-0.8	1.3	0.7	0.5	0.3	0.4	1.3	0.7	-1.6	-1.2	-0.9	-0.1
Comparative height size at age 10	2.1	11.6	34.3	-4.3	-0.8	3.2	2.9	-1.4	3.7	2.9	4.3	-3.2	-5.9	-3.6	0.8
Number of full sisters	0.6	0.7	1.8	-0.9	0.7	-0.8	-1.0	0.0	1.3	1.0	0.8	0.8	-0.5	0.9	0.5
Suffer from ‘nerves’	0.5	0.8	1.6	0.1	0.4	1.2	0.4	-0.9	1.3	1.2	0.5	0.7	-1.1	-0.8	1.0
Overall health rating	0.4	0.8	2.3	0.1	0.9	-0.3	-0.7	0.4	0.9	1.2	0.9	-0.7	-1.5	-0.2	-1.3
Chest pain or discomfort	1.3	1.8	2.9	-1.4	-0.6	1.5	1.2	-1.7	1.6	1.2	1.7	-1.4	-1.3	-1.6	0.2
Had major operations	2.2	2.6	6.6	-0.4	-1.9	1.9	2.1	-2.6	0.1	-1.1	1.4	-0.7	-1.7	-2.0	-1.4
Age at last live birth	1.0	1.4	6.4	0.5	-0.7	1.6	1.4	-2.5	-0.7	-1.0	0.4	1.0	-0.4	-1.5	-0.4
Family relationship satisfaction	0.5	0.6	2.9	-0.9	-0.8	0.7	0.6	-0.0	0.1	0.6	1.7	0.5	-0.2	-0.4	1.2
Leg pain on walking	0.2	0.2	1.1	0.1	1.1	0.5	-0.1	-0.0	0.4	0.8	0.2	0.3	-0.5	-0.5	-0.3
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	6.6	-0.9	2.6	0.9	0.7	-0.3	-0.4	0.1	0.5	-1.8	-0.6	-1.0	-0.8
Commuting to job workplace: Car/motor vehicle	3.7	4.3	8.0	2.1	1.1	-2.8	-1.9	2.3	-2.1	-2.4	-1.4	0.8	1.7	2.6	-2.5
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.7	-0.6	-0.1	0.3	0.8	-0.5	-0.1	-0.6	0.1	-0.4	0.6	-0.4	0.5
Medication: Aspirin	0.5	0.6	2.8	-1.2	0.9	0.2	0.1	-0.2	1.7	0.7	-0.0	-0.9	-0.8	-0.4	0.5
Supplements: Vitamin C	1.6	1.9	8.6	-0.3	0.9	-1.2	-0.9	2.2	0.0	-0.1	-2.9	0.9	1.7	1.1	1.2
Knee pain experienced in last month	0.8	1.2	3.9	1.2	1.1	-1.2	-1.8	0.4	-0.9	-0.3	-0.7	0.0	0.4	1.2	-2.0
Hypertension (Self-reported)	0.2	0.5	3.6	0.6	0.4	-0.1	0.0	-0.0	0.5	0.1	-0.5	-0.4	1.9	0.0	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	5.1	2.3	1.7	-0.0	0.3	0.0	-1.6	-1.9	-1.1	0.9	1.2	0.2	-0.4
Illnesses of father: Heart disease	0.6	0.8	3.6	-0.0	0.2	-0.4	-0.2	0.1	0.4	-0.4	-1.9	1.3	1.7	0.5	0.9
Illnesses of siblings: Diabetes	0.4	0.5	1.5	-0.5	0.9	0.1	-0.3	-0.3	1.2	1.2	1.2	-0.4	-0.4	0.0	0.7
Smoking status: Previous	0.2	0.4	1.4	0.8	0.1	0.3	0.6	0.5	0.4	-1.2	0.4	0.8	0.3	-0.1	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	4.9	-0.5	-1.1	1.4	1.5	-1.0	0.3	0.4	1.3	-1.4	-2.2	-1.7	-1.2
Whole body fat-free mass	1.5	8.4	22.7	-4.3	0.2	2.4	2.1	-1.3	1.9	2.5	3.5	-4.0	-4.8	-3.0	-0.7
Leg fat-free mass (right)	1.6	8.5	22.8	-4.4	0.1	2.7	2.3	-1.3	2.1	2.6	3.6	-3.5	-4.8	-3.1	-0.2
Arm fat percentage (left)	0.5	1.9	6.7	-1.4	0.5	-1.2	-1.7	1.3	1.4	2.6	0.5	0.6	-0.0	1.3	1.8
Average weekly red wine intake	1.3	1.8	8.5	0.8	-0.7	-0.0	0.4	-1.2	-0.6	-1.4	-0.6	2.9	2.4	0.5	1.5
Handedness (chirality/laterality): Left-handed	0.5	0.5	1.1	0.7	0.4	1.1	1.1	-0.9	-0.3	-0.6	-0.3	0.4	0.7	-0.9	0.9
Mood swings	0.1	0.2	1.0	1.0	-0.1	0.4	-0.1	0.4	0.6	0.6	0.6	-0.2	-0.1	-0.2	-0.0
Loneliness, isolation	1.1	1.5	6.0	-0.9	-2.4	0.4	0.3	0.1	0.0	0.4	1.6	-1.8	-1.9	-0.6	-1.1
Long-standing illness, disability or infirmity	0.5	0.8	3.1	0.6	1.5	-1.2	-0.9	1.8	-0.8	0.4	-0.1	-0.4	-0.2	1.0	0.3
Ever had bowel cancer screening	0.9	1.0	2.5	-0.5	0.7	0.8	1.3	0.2	-1.6	-1.4	-0.6	-1.3	-0.6	-1.2	-1.0
Diabetes diagnosed by doctor	0.5	0.8	2.8	-0.2	1.2	-1.0	-1.0	0.4	0.2	1.7	-0.2	-0.4	0.0	1.0	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	2.3	0.7	1.2	0.5	1.0	-0.0	-1.1	-1.5	0.2	-0.0	0.3	-0.6	-0.8
Friendships satisfaction	2.0	2.5	5.4	-2.0	-1.1	1.8	1.6	-0.8	1.0	0.4	2.3	-1.3	-2.3	-2.0	-0.8
Qualifications: nursing, teaching	0.3	0.5	1.0	-0.0	0.2	0.9	0.6	-0.9	-0.6	0.7	1.0	-0.4	-0.8	-0.6	0.7
Commuting to job workplace: Walk	4.5	4.8	11.1	-2.1	-0.4	3.3	3.2	-2.0	1.9	0.9	1.6	0.7	-1.6	-3.1	2.9
Eye problems/disorders: Cataract	1.1	1.2	3.0	1.3	1.4	-0.7	0.5	1.7	-1.4	-1.7	-0.7	-0.1	1.3	0.5	0.4
Mouth/teeth dental problems: Mouth ulcers	3.5	5.6	14.6	-2.2	-1.1	3.8	3.5	-2.6	1.5	0.2	2.6	-1.9	-0.7	-3.5	1.2
Medication for cholesterol	0.2	0.3	2.3	0.1	-1.5	0.1	-0.0	0.4	-1.0	-0.2	0.1	0.3	-0.3	0.0	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	4.7	-2.1	-0.3	0.4	0.2	-0.1	1.7	2.1	1.9	-1.0	-2.2	-0.4	1.1
Back pain experienced in last month	0.3	0.5	1.9	0.9	0.7	-0.1	-0.9	-0.3	-0.1	1.4	-0.3	-1.1	-0.2	0.3	-0.4
Mineral and other dietary supplements	0.9	1.2	5.2	-1.8	0.0	0.6	0.7	-0.0	0.5	-0.0	1.3	-1.0	-2.3	-0.8	-1.1
Breast cancer (self-reported)	1.1	1.3	4.5	-0.5	2.1	-1.0	-1.2	1.3	0.1	1.6	-0.6	0.3	0.0	1.2	1.6
Asthma (self-reported)	0.9	1.8	5.1	0.7	1.4	-1.6	-1.3	0.5	-1.4	-0.7	-2.3	0.7	2.1	1.5	0.1
Osteoporosis (self-reported)	1.4	1.7	5.0	-0.0	1.7	1.2	1.6	-0.6	-1.5	-1.4	-0.9	-0.8	2.2	-0.9	1.2
Osteoarthritis (self-reported)	0.2	0.3	0.9	-0.3	-0.5	-0.0	-0.3	-0.1	1.0	0.9	0.8	-0.3	-0.4	-0.1	-0.2
Medication: Aspirin	0.5	0.6	2.5	-1.1	0.8	-0.1	-0.3	-0.3	1.6	0.9	-0.3	-1.0	-0.7	-0.0	0.7
Medication: Gliclazide	0.3	0.4	2.2	0.3	0.6	0.3	0.3	-0.3	-1.5	0.8	-0.2	-0.6	0.3	-0.2	0.8
Illnesses of father: None of the above (group 1)	0.6	0.7	2.2	1.1	1.5	-1.0	-0.7	1.1	-1.2	-0.3	-0.2	-0.2	0.3	0.9	-0.6
Smoking status: Current	5.0	8.0	16.7	-2.6	0.1	3.8	3.8	-3.5	1.1	0.9	3.3	-3.0	-3.0	-4.1	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.5	2.2	-0.6	-0.6	0.5	0.6	-0.2	0.9	-0.4	0.4	-1.5	-0.9	-0.7	-0.8
Whole body water mass	1.4	7.8	21.3	-4.3	0.3	2.4	2.0	-1.2	1.9	2.4	3.3	-3.9	-4.6	-2.9	-0.6
Leg predicted mass (right)	1.7	8.8	23.2	-4.5	0.1	2.8	2.4	-1.4	2.2	2.6	3.7	-3.5	-4.8	-3.2	-0.1
Arm fat mass (left)	0.6	2.3	9.2	-2.5	0.6	-0.5	-1.0	0.9	1.9	3.0	1.3	-0.9	-1.5	0.3	1.1
Number of self-reported non-cancer illnesses	0.9	1.6	4.3	0.4	2.1	-1.7	-1.8	1.3	-0.2	0.7	-1.9	-0.6	0.7	1.5	-0.2
Average weekly champagne plus white wine intake	1.2	1.7	6.3	1.3	0.4	-1.1	-1.8	0.3	-0.5	0.5	-1.0	2.5	1.6	1.6	1.1
Miserableness	0.5	0.9	3.9	2.0	-1.2	0.8	0.5	-0.1	0.0	-1.2	-1.0	0.9	0.3	-0.8	-0.5
Guilty feelings	2.1	3.2	9.0	3.0	-0.3	-2.1	-1.6	1.8	-1.7	-1.6	-2.1	1.1	0.8	1.9	-1.7
Wears glasses or contact lenses	0.2	0.2	0.6	0.6	-0.1	0.0	0.3	0.1	-0.7	-0.6	-0.3	0.3	0.8	0.4	0.6
Ever taken oral contraceptive pill	0.8	0.8	2.9	0.4	-1.3	-1.3	-1.1	0.3	0.7	-0.3	0.2	1.7	0.4	1.3	-0.1
Hearing aid user	0.9	1.1	3.6	0.4	0.5	1.3	1.4	-1.9	0.5	0.0	0.7	-1.1	0.9	-1.4	0.8
Mother’s age at death	0.1	0.1	0.5	0.1	0.1	0.1	-0.0	-0.4	-0.1	0.3	0.4	-0.7	-0.1	0.1	0.0
Financial situation satisfaction	0.6	0.8	2.3	-0.6	-0.0	-0.7	-1.1	1.1	1.0	0.8	0.5	-0.9	-1.0	0.5	-1.5
Tinnitus: Yes, now most or all of the time	0.4	0.5	2.1	-0.6	-0.5	-0.2	-0.1	1.4	1.1	0.6	-0.9	-0.5	-0.3	0.2	0.6
Commuting to job workplace: Public transport	1.6	1.9	4.4	-1.0	0.3	1.9	0.8	-2.1	1.7	1.7	0.5	-0.2	-1.8	-1.8	0.4
Eye problems/disorders: Glaucoma	0.8	0.9	3.2	1.6	0.8	-0.2	-0.2	0.6	-0.7	-1.0	-1.6	0.6	1.8	0.1	0.3
Medication: Blood pressure	0.2	0.3	2.0	-0.0	0.7	-0.5	-0.6	0.2	0.5	0.7	0.1	-1.4	0.3	0.2	-0.4
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.4	0.4	0.4	0.2	-0.0	0.6	0.1	0.3	-0.2	-0.7	-0.4	-0.4	-0.4
Supplements: Fish oil (including cod liver oil)	1.5	2.0	5.3	1.8	0.4	-1.6	-1.9	1.2	-0.2	0.3	-2.3	1.4	1.8	1.6	-0.2
High cholesterol (Self-reported)	0.3	0.6	2.5	-0.1	1.6	0.5	1.1	0.4	0.6	-1.0	-0.4	-0.5	-0.9	-0.6	-0.2
Medication: Bendroflumethiazide	1.5	2.4	7.1	-2.0	-0.3	1.7	1.6	-2.0	0.3	0.7	2.7	-1.9	-0.2	-1.7	0.5
Medication: Paracetamol	0.6	1.0	3.9	0.9	0.3	-0.8	-0.4	1.6	-0.5	-0.8	-1.2	0.3	2.0	0.8	0.4
Medication: Lisinopril	0.4	0.5	3.3	0.5	-1.8	0.4	0.3	-1.1	-0.3	-0.2	-0.0	0.2	0.5	-0.3	-0.2
Medication: Atorvastatin	0.3	0.3	1.4	0.4	0.7	-0.1	-0.1	0.3	-0.3	-0.8	-0.9	-0.1	0.3	0.0	-1.2
Illnesses of father: High blood pressure	0.6	0.7	1.7	-0.3	-0.7	0.9	0.5	-1.2	0.8	1.0	1.3	-0.8	0.0	-0.6	1.1
Alcohol drinker status: Never	0.5	0.5	2.2	0.5	0.5	0.1	0.6	0.8	-0.5	-1.5	-1.1	0.1	1.1	-0.2	-0.3
Ever smoked	0.8	1.4	4.2	-0.4	0.2	1.7	2.0	-0.3	0.4	-0.1	1.8	-1.0	-1.2	-1.8	0.9
Basal metabolic rate	1.3	7.1	20.2	-4.1	0.2	1.9	1.5	-0.9	1.9	2.8	3.3	-3.6	-4.5	-2.4	-0.5
Leg fat percentage (left)	1.0	3.5	10.2	-0.2	0.6	-2.8	-3.2	2.4	0.6	2.5	-0.3	0.7	1.0	2.9	1.1
Arm fat-free mass (left)	1.1	5.5	15.1	-3.8	0.7	1.1	0.8	-0.2	1.7	2.6	2.4	-3.9	-3.9	-1.6	-0.9
Number of operations (self-reported)	3.0	4.4	14.1	-1.5	-0.1	3.0	2.4	-3.8	1.9	0.7	2.2	0.0	-1.9	-2.9	0.5
Average weekly beer plus cider intake	3.4	4.9	12.0	-3.5	-0.5	2.0	1.4	-0.0	2.7	2.1	2.7	-2.3	-3.3	-2.2	0.7
Irritability	1.2	2.0	6.3	0.1	-1.2	2.5	1.5	-2.1	0.5	0.6	-0.4	1.4	-0.3	-1.9	1.6
Risk taking	1.0	1.4	4.1	-0.8	1.2	1.3	2.0	0.4	0.2	-0.3	0.7	-1.8	-1.6	-1.6	-0.2
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.5	-0.7	0.7	-0.1	0.5	-0.6	0.3	-0.2	0.3	-0.7	0.6	-0.0	0.7
Fractured/broken bones in last 5 years	0.7	0.9	2.1	-0.8	-1.5	0.9	1.2	-0.9	0.5	-0.4	1.4	-1.2	0.5	-1.0	-0.0
Age started oral contraceptive pill	0.3	0.4	1.5	0.2	1.2	-0.4	-0.5	-0.3	-0.1	-0.1	-0.6	0.8	0.9	0.6	0.2
Diastolic blood pressure, automated reading	1.6	5.1	12.7	1.6	1.3	-3.3	-2.9	3.3	-1.0	0.4	-1.9	1.7	1.8	3.6	1.7
Ever depressed for a whole week	0.2	0.3	0.7	-0.0	0.4	0.7	0.1	-0.4	0.8	0.7	-0.0	0.3	-0.4	-0.6	0.7
Unable to work because of sickness or disability	0.5	0.7	4.3	-0.5	-2.1	-0.5	-0.3	1.4	0.5	0.8	0.3	-0.4	-0.5	0.3	0.3
Commuting to job workplace: Cycle	1.0	1.2	2.8	-0.1	-1.1	1.6	1.7	-1.3	1.1	-0.1	0.6	0.7	0.3	-1.4	1.3
Myopia	0.6	0.9	1.8	0.8	-0.5	-1.1	-1.3	0.1	-1.1	0.5	-1.2	-0.5	0.7	1.2	-1.1
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.1	0.0	0.1	0.3	0.3	-0.3	-0.6	-0.8	-0.0	0.6	-0.9	-0.2	-1.0
Cholesterol lowering medication	0.3	0.4	1.7	-0.1	1.3	-0.8	-0.6	0.0	1.1	0.2	-0.4	0.6	-0.1	0.6	0.2
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	4.6	1.8	0.6	-1.0	-0.6	1.8	-1.4	-1.5	-0.9	0.7	2.1	1.2	-0.1
Pain experienced in last month	0.8	1.3	3.8	-1.3	-1.9	0.8	1.3	-0.9	0.4	-0.3	1.3	1.2	0.1	-0.6	1.8
Supplements: Calcium	0.9	1.0	6.4	-0.5	2.5	-0.6	-0.6	1.6	-0.0	1.0	-0.5	-0.6	-0.2	0.6	0.7
Basal cell carcinoma (self-reported)	0.4	0.5	3.2	0.1	-1.8	0.1	-0.2	-1.0	-0.7	0.6	0.4	-0.5	0.1	-0.1	-0.3
Heart attack/myocardial infarction (self-reported)	1.4	1.8	7.3	-2.7	0.6	-0.2	-0.4	-0.3	2.1	1.5	1.3	-1.8	-1.3	-0.3	0.0
Deep venous thrombosis (DVT) (self-reported)	2.3	3.0	7.7	-2.2	1.1	1.7	1.4	-1.7	1.4	0.2	1.7	-2.8	-1.6	-2.0	-1.6
Heart disease (siblings)	0.7	0.9	2.6	1.1	-0.3	-1.1	-0.7	0.7	0.1	-0.8	-0.6	1.6	1.5	1.0	0.7
Alcohol drinker status: Previous	0.3	0.4	1.5	0.1	0.5	0.1	0.4	0.8	0.4	-0.2	1.0	-1.2	-0.8	-0.3	-0.5
Pack years of smoking	3.5	5.1	11.2	-2.6	-0.1	3.1	3.3	-1.9	1.8	-0.4	3.1	-1.3	-2.1	-3.4	0.2
Impedance of whole body	0.1	0.7	4.3	0.9	-0.2	-0.5	-0.6	0.7	0.8	0.0	-0.5	2.1	-0.1	0.6	0.8
Leg fat mass (left)	0.5	1.9	7.5	-1.5	0.7	-1.3	-1.6	1.7	1.1	2.7	0.9	-0.5	-0.9	1.2	0.9
Arm predicted mass (left)	1.0	5.0	14.5	-3.5	0.6	1.0	0.7	-0.2	1.4	2.4	2.4	-3.8	-3.8	-1.5	-1.2