TWAS hub - TULP4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1650	0.0380	2.7e-11	0.080	0.115	0.117	0.119	0.115	6.0e-10	7.1e-14	4.4e-14	2.9e-14	7.7e-14
2	GTEx	Adipose Visceral Omentum	0.1530	0.0650	8.7e-03	-0.004	NA	0.000	NA	-0.002	5.6e-01	NA	3.1e-01	NA	4.2e-01
3	GTEx	Brain Cerebellar Hemisphere	0.4370	0.0880	3.1e-07	0.370	NA	0.247	NA	0.324	1.9e-10	NA	5.2e-07	NA	4.3e-09
4	GTEx	Brain Cerebellum	0.4610	0.0850	1.1e-07	0.316	NA	0.201	NA	0.278	4.7e-10	NA	1.4e-06	NA	7.6e-09
5	GTEx	Esophagus Mucosa	0.3780	0.0750	3.7e-09	0.275	NA	0.290	NA	0.265	1.4e-18	NA	1.2e-19	NA	6.9e-18
6	GTEx	Muscle Skeletal	0.0757	0.0307	1.2e-03	0.010	NA	0.024	NA	0.013	3.5e-02	NA	1.9e-03	NA	1.6e-02
7	GTEx	Stomach	0.2510	0.0620	6.5e-07	0.180	NA	0.144	NA	0.165	5.2e-09	NA	2.3e-07	NA	2.7e-08
8	GTEx	Thyroid	0.0950	0.0340	1.3e-03	0.025	NA	0.011	NA	0.033	4.9e-03	NA	4.5e-02	NA	1.4e-03
9	ROSMAP	Brain Pre-frontal Cortex	0.0691	0.0262	1.2e-03	0.018	0.017	0.025	0.017	0.029	1.7e-03	2.8e-03	2.8e-04	2.7e-03	1.2e-04
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0879	0.0436	4.5e-04	0.046	0.041	0.037	NA	0.039	6.6e-06	2.0e-05	5.2e-05	NA	3.2e-05
11	TCGA	Brain Lower Grade Glioma	0.0320	0.0175	4.9e-03	0.028	0.015	0.009	NA	0.016	3.2e-04	7.4e-03	3.2e-02	NA	5.1e-03
12	TCGA	Prostate Adenocarcinoma	0.0569	0.0317	7.0e-03	0.014	0.007	0.016	NA	0.009	1.1e-02	5.7e-02	8.1e-03	NA	3.7e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Forced vital capacity (FVC)	6.5	25.0	57.6	-5.3	-1.8	6.5	5.4	-5.0	3.9	2.4	5.5	-4.5	-7.6	-6.7	-0.3
Forced vital capacity (FVC), Best measure	5.7	20.7	47.7	-4.4	-1.9	5.9	5.3	-5.0	2.8	1.3	5.1	-4.0	-6.9	-6.2	-0.8
Lung FVC	5.3	27.1	50.9	-5.6	-2.0	7.1	6.5	-5.7	3.9	2.0	5.3	-5.0	-6.2	-7.1	1.5
Forced expiratory volume in 1-second (FEV1)	5.2	17.7	40.3	-4.6	-1.4	5.1	4.4	-3.9	3.1	1.6	5.2	-4.5	-6.3	-5.3	-1.3
Number of incorrect matches in round	5.1	8.4	22.8	-3.9	0.7	1.8	1.5	-2.1	0.9	2.6	4.8	-4.7	-4.1	-2.1	-1.2
Smoking status: Current	5.0	8.0	16.7	-2.6	0.1	3.8	3.8	-3.5	1.1	0.9	3.3	-3.0	-3.0	-4.1	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	4.6	14.7	31.1	-3.6	-1.9	4.8	4.2	-4.1	2.4	0.9	5.0	-3.6	-5.6	-4.9	-1.2
Commuting to job workplace: Walk	4.5	4.8	11.1	-2.1	-0.4	3.3	3.2	-2.0	1.9	0.9	1.6	0.7	-1.6	-3.1	2.9
Pack years adult smoking proportion	4.0	6.1	13.4	-2.7	-0.4	3.3	3.6	-2.0	1.6	-0.4	3.4	-1.9	-2.5	-3.7	-0.3
Current tobacco smoking	3.7	6.0	13.1	-2.2	0.2	3.3	3.4	-3.2	0.7	0.4	2.7	-2.6	-2.5	-3.6	0.4
Commuting to job workplace: Car/motor vehicle	3.7	4.3	8.0	2.1	1.1	-2.8	-1.9	2.3	-2.1	-2.4	-1.4	0.8	1.7	2.6	-2.5
Peak expiratory flow (PEF)	3.5	8.2	23.6	-4.2	-2.3	1.9	2.1	-1.2	2.2	1.3	4.9	-3.7	-4.0	-2.3	-1.0
Mouth/teeth dental problems: Mouth ulcers	3.5	5.6	14.6	-2.2	-1.1	3.8	3.5	-2.6	1.5	0.2	2.6	-1.9	-0.7	-3.5	1.2
Pack years of smoking	3.5	5.1	11.2	-2.6	-0.1	3.1	3.3	-1.9	1.8	-0.4	3.1	-1.3	-2.1	-3.4	0.2
Mouth/teeth dental problems	3.4	5.2	16.0	2.8	1.4	-2.2	-2.0	1.0	-4.0	-1.6	-3.3	1.2	2.2	2.2	-1.4
Average weekly beer plus cider intake	3.4	4.9	12.0	-3.5	-0.5	2.0	1.4	-0.0	2.7	2.1	2.7	-2.3	-3.3	-2.2	0.7
Hand grip strength (right)	3.3	8.9	20.1	-3.9	-0.5	3.2	2.7	-2.5	3.5	2.1	3.0	-3.1	-4.5	-3.6	0.0
Birth weight	3.3	7.2	19.9	-2.5	0.2	3.1	2.9	-1.3	-0.4	-0.5	2.2	-3.9	-4.5	-3.6	-2.7
Height	3.1	59.2	179.6	-10.9	0.6	7.3	6.1	-3.8	6.6	6.3	9.4	-8.1	-13.4	-8.3	-0.6
Ever used hormone-replacement therapy (HRT)	3.0	3.9	8.5	1.7	1.0	-2.2	-2.5	1.5	-0.2	0.5	-2.5	2.5	2.9	2.5	1.3
Number of operations (self-reported)	3.0	4.4	14.1	-1.5	-0.1	3.0	2.4	-3.8	1.9	0.7	2.2	0.0	-1.9	-2.9	0.5
Average weekly spirits intake	2.9	3.6	7.5	2.0	1.2	-2.7	-2.0	2.1	-1.3	-1.2	-2.1	1.9	1.8	2.7	0.2
Sitting height	2.9	20.4	59.0	-5.8	-0.2	4.6	4.1	-2.3	3.2	3.3	5.7	-5.3	-7.7	-5.2	-0.3
Blood clot in the leg (DVT)	2.9	3.7	9.5	-2.4	1.5	1.8	1.4	-2.1	1.6	0.8	2.0	-3.1	-1.8	-2.1	-1.3
Age at First Birth	2.8	4.0	8.9	-2.6	-0.8	3.0	2.5	-2.9	1.6	0.3	2.1	-0.6	-1.0	-2.5	1.4
Bipolar Disorder (2011)	2.7	2.7	7.6	0.1	-0.9	1.8	2.2	-1.7	-2.0	-2.8	1.0	-0.8	0.1	-1.9	-1.9
Diverticular disease/diverticulitis (self-reported)	2.7	3.2	13.9	3.7	2.9	-0.5	-1.1	0.8	-1.7	0.0	-2.5	1.7	1.0	0.7	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	2.7	6.1	15.1	2.7	0.3	-3.5	-3.9	1.9	-1.1	0.6	-2.6	2.8	2.3	3.7	-0.3
Smoking Status	2.5	6.0	11.8	-1.6	1.4	3.4	2.8	-2.4	1.7	1.2	3.1	-2.7	-3.0	-3.4	0.6
Hearing difficulty/problems: Yes	2.5	3.8	6.7	-0.5	-1.0	2.6	2.2	-2.2	2.1	2.1	2.5	-0.5	-1.2	-2.3	2.5
Blood White Count	2.4	18.1	35.3	5.1	2.4	-4.5	-2.6	4.3	-5.1	-4.6	-5.9	2.1	5.8	4.1	-1.6
Pain all over the body in last month	2.4	2.6	9.3	-1.9	-0.9	0.0	0.3	0.7	1.0	2.0	3.1	-2.4	-2.5	-0.3	-0.3
Hypothyroidism/myxoedema (self-reported)	2.4	4.7	9.9	3.1	-0.1	-2.7	-2.4	2.5	-2.0	-0.8	-2.1	2.5	1.8	2.8	-0.5
Deep venous thrombosis (DVT) (self-reported)	2.3	3.0	7.7	-2.2	1.1	1.7	1.4	-1.7	1.4	0.2	1.7	-2.8	-1.6	-2.0	-1.6
Hand grip strength (left)	2.2	5.8	11.6	-3.0	-1.1	3.0	2.8	-2.6	2.9	0.8	2.2	-1.4	-2.9	-3.4	0.2
Had major operations	2.2	2.6	6.6	-0.4	-1.9	1.9	2.1	-2.6	0.1	-1.1	1.4	-0.7	-1.7	-2.0	-1.4
Standing height	2.1	20.9	66.7	-5.7	0.0	4.8	4.2	-2.3	3.5	3.2	5.7	-4.7	-8.2	-5.4	-0.7
Comparative height size at age 10	2.1	11.6	34.3	-4.3	-0.8	3.2	2.9	-1.4	3.7	2.9	4.3	-3.2	-5.9	-3.6	0.8
Guilty feelings	2.1	3.2	9.0	3.0	-0.3	-2.1	-1.6	1.8	-1.7	-1.6	-2.1	1.1	0.8	1.9	-1.7
Diabetes (mother)	2.0	2.6	8.7	-2.0	0.5	1.3	0.7	-1.0	2.1	1.5	2.3	-0.9	-3.0	-1.3	0.1
Friendships satisfaction	2.0	2.5	5.4	-2.0	-1.1	1.8	1.6	-0.8	1.0	0.4	2.3	-1.3	-2.3	-2.0	-0.8
Verbal and Numeric Reasoning (VNR)	1.9	4.6	18.7	2.5	-0.1	-0.5	-0.4	0.5	-0.4	-1.1	-2.2	3.8	4.3	1.2	2.8
Heel T-Score	1.9	15.3	32.1	5.2	2.9	-4.3	-4.7	1.4	-3.7	-1.4	-4.3	4.1	5.7	4.9	-0.7
Medication: Levothyroxine sodium	1.9	3.2	7.2	2.3	-0.2	-2.4	-2.3	2.7	-1.5	-0.4	-1.3	1.5	0.5	2.5	-1.2
Alcohol usually taken with meals	1.8	2.9	9.5	1.8	0.2	-1.1	-0.9	-0.2	-1.5	-1.4	-2.3	3.1	2.7	1.5	0.7
Loud music exposure frequency	1.8	2.0	4.8	1.3	-0.9	1.5	1.3	-1.3	-0.5	-2.1	-1.4	-0.9	0.3	-1.7	-2.2
Eye problems/disorders: None of the above	1.8	2.1	6.9	-1.5	-1.8	0.1	-0.7	-1.0	1.3	1.7	1.0	-1.4	-2.6	-0.2	-1.8
Mouth/teeth dental problems: Dentures	1.7	2.9	9.3	-2.3	0.8	1.2	0.8	-0.9	3.1	2.2	2.1	-1.1	-1.6	-1.3	1.3
Leg predicted mass (right)	1.7	8.8	23.2	-4.5	0.1	2.8	2.4	-1.4	2.2	2.6	3.7	-3.5	-4.8	-3.2	-0.1
Schizophrenia vs Biploar Disorder	1.6	2.1	5.9	1.3	0.4	-2.0	-2.4	2.0	-0.3	1.2	-1.8	0.2	-0.7	1.9	-0.7
Reaction Time	1.6	3.1	7.6	1.6	0.7	-2.1	-1.9	2.2	-1.0	-1.4	-2.1	2.8	0.9	2.0	-1.2
Hypothyroidism (self reported)	1.6	3.7	7.6	2.8	-1.1	-2.6	-2.5	2.3	-1.8	-0.2	-1.6	1.6	1.3	2.6	-0.9
Respiratory disease	1.6	3.5	9.4	1.7	0.5	-2.6	-2.1	1.6	-1.5	-1.1	-3.1	0.7	2.4	2.3	-0.9
Angina (self-reported)	1.6	2.1	6.6	-2.6	-0.7	0.3	-0.2	-0.7	1.7	2.1	1.7	-2.0	-1.7	-0.6	-0.4
Supplements: Vitamin C	1.6	1.9	8.6	-0.3	0.9	-1.2	-0.9	2.2	0.0	-0.1	-2.9	0.9	1.7	1.1	1.2
Leg fat-free mass (right)	1.6	8.5	22.8	-4.4	0.1	2.7	2.3	-1.3	2.1	2.6	3.6	-3.5	-4.8	-3.1	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	4.7	-2.1	-0.3	0.4	0.2	-0.1	1.7	2.1	1.9	-1.0	-2.2	-0.4	1.1
Commuting to job workplace: Public transport	1.6	1.9	4.4	-1.0	0.3	1.9	0.8	-2.1	1.7	1.7	0.5	-0.2	-1.8	-1.8	0.4
Diastolic blood pressure, automated reading	1.6	5.1	12.7	1.6	1.3	-3.3	-2.9	3.3	-1.0	0.4	-1.9	1.7	1.8	3.6	1.7
Intelligence (Savage-Jansen 2018)	1.5	4.5	19.4	2.1	-0.5	-0.7	-0.6	0.8	-1.1	-0.6	-2.1	3.5	4.4	1.4	2.9
Sensitivity / hurt feelings	1.5	2.6	9.5	2.4	-0.6	-1.1	-0.6	1.2	-3.1	-2.0	-1.4	-0.2	1.2	1.1	-1.9
Leg fat-free mass (left)	1.5	7.8	20.5	-4.1	0.1	2.6	2.2	-1.3	2.1	2.6	3.5	-3.3	-4.5	-3.0	-0.0
Leg predicted mass (left)	1.5	8.0	20.3	-4.2	-0.0	2.7	2.3	-1.4	2.1	2.5	3.5	-3.3	-4.5	-3.1	-0.1
Trunk fat-free mass	1.5	8.4	21.8	-4.2	0.2	2.5	2.3	-1.4	1.6	2.2	3.5	-4.2	-4.7	-3.0	-0.9
Trunk predicted mass	1.5	8.3	22.5	-4.2	0.2	2.5	2.2	-1.4	1.6	2.2	3.4	-4.1	-4.7	-3.0	-0.9
Mouth/teeth dental problems: Loose teeth	1.5	1.8	3.9	-1.0	-1.3	1.9	1.9	-1.5	0.2	0.1	1.7	-0.8	-1.4	-2.0	0.1
Whole body fat-free mass	1.5	8.4	22.7	-4.3	0.2	2.4	2.1	-1.3	1.9	2.5	3.5	-4.0	-4.8	-3.0	-0.7
Supplements: Fish oil (including cod liver oil)	1.5	2.0	5.3	1.8	0.4	-1.6	-1.9	1.2	-0.2	0.3	-2.3	1.4	1.8	1.6	-0.2
Medication: Bendroflumethiazide	1.5	2.4	7.1	-2.0	-0.3	1.7	1.6	-2.0	0.3	0.7	2.7	-1.9	-0.2	-1.7	0.5
Alzheimer’s Disease (in father)	1.4	1.6	2.8	1.4	1.7	-1.1	-1.5	1.5	-1.3	-0.0	-1.4	0.8	-0.1	1.1	-1.7
Primary Biliary Cirrhosis	1.4	2.0	4.5	1.3	-1.0	-2.0	-1.5	1.6	-0.6	-1.6	-0.8	0.8	2.1	1.8	-0.7
Angina	1.4	1.8	5.5	-2.3	-0.8	0.1	-0.4	-0.4	1.5	2.1	1.6	-1.8	-1.6	-0.4	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	9.4	1.9	1.4	-2.5	-3.1	1.3	-0.5	1.3	-1.8	1.6	1.4	2.6	-0.3
Father’s age at death	1.4	1.9	6.1	-1.4	-0.4	2.0	1.8	-2.5	0.4	0.2	1.1	-0.3	-0.1	-1.6	1.6
Glaucoma (self-reported)	1.4	1.7	5.5	2.1	0.6	-0.4	-0.2	0.8	-1.1	-1.8	-2.4	1.0	1.9	0.3	0.0
Emphysema/chronic bronchitis	1.4	1.6	3.7	-1.7	0.2	1.4	1.2	-1.8	0.8	0.6	1.2	-0.9	-1.9	-1.5	-0.6
Osteoporosis (self-reported)	1.4	1.7	5.0	-0.0	1.7	1.2	1.6	-0.6	-1.5	-1.4	-0.9	-0.8	2.2	-0.9	1.2
Whole body water mass	1.4	7.8	21.3	-4.3	0.3	2.4	2.0	-1.2	1.9	2.4	3.3	-3.9	-4.6	-2.9	-0.6
Heart attack/myocardial infarction (self-reported)	1.4	1.8	7.3	-2.7	0.6	-0.2	-0.4	-0.3	2.1	1.5	1.3	-1.8	-1.3	-0.3	0.0
Systolic blood pressure, automated reading	1.3	3.6	6.7	2.1	0.8	-2.5	-2.3	1.6	-0.7	-0.4	-2.6	1.8	2.6	2.6	1.0
Hearing difficulty/problems with background noise	1.3	2.1	5.2	-0.4	-1.1	1.6	1.0	-1.5	2.3	1.8	1.8	0.2	-1.0	-1.3	1.8
Heart attack	1.3	1.7	6.8	-2.6	0.5	-0.3	-0.5	-0.3	2.1	1.4	1.1	-1.8	-1.3	-0.3	-0.2
Chronic bronchitis/emphysema (mother)	1.3	1.5	4.5	1.4	0.8	-0.2	0.2	1.0	-1.1	-2.1	-1.0	1.6	1.9	0.3	-1.1
Health satisfaction	1.3	1.6	5.2	1.3	0.2	-1.6	-1.7	1.4	-1.0	-0.5	-1.2	1.0	-0.6	1.2	-2.3
Chest pain or discomfort	1.3	1.8	2.9	-1.4	-0.6	1.5	1.2	-1.7	1.6	1.2	1.7	-1.4	-1.3	-1.6	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	5.1	2.3	1.7	-0.0	0.3	0.0	-1.6	-1.9	-1.1	0.9	1.2	0.2	-0.4
Average weekly red wine intake	1.3	1.8	8.5	0.8	-0.7	-0.0	0.4	-1.2	-0.6	-1.4	-0.6	2.9	2.4	0.5	1.5
Basal metabolic rate	1.3	7.1	20.2	-4.1	0.2	1.9	1.5	-0.9	1.9	2.8	3.3	-3.6	-4.5	-2.4	-0.5
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	4.6	1.8	0.6	-1.0	-0.6	1.8	-1.4	-1.5	-0.9	0.7	2.1	1.2	-0.1
Hair Pigment	1.2	34.1	225.0	5.3	2.4	-1.5	-0.2	4.6	-7.2	-5.5	-15.0	2.4	6.0	1.5	-0.6
Diabetes (father)	1.2	1.5	3.7	-1.0	-0.4	1.0	0.4	-1.0	1.4	1.9	1.9	-0.5	-1.8	-1.0	1.2
Severe depression (siblings)	1.2	1.3	7.4	-0.6	-2.7	1.2	1.0	-1.0	-0.0	0.5	1.2	-0.8	-0.8	-1.3	-0.5
Townsend deprivation index at recruitment	1.2	1.7	3.6	-1.4	0.6	1.4	0.9	-0.6	1.8	1.4	1.9	-0.8	-1.7	-1.6	0.1
Maternal smoking around birth	1.2	1.8	6.9	-0.4	0.2	1.7	1.1	-0.7	2.6	0.3	0.9	2.1	-0.3	-1.3	1.5
Lung cancer (father)	1.2	1.5	5.0	1.9	1.3	-0.8	-0.6	1.0	-1.3	-0.7	-1.1	0.3	2.2	1.0	0.8
Arm fat-free mass (right)	1.2	5.9	16.8	-3.8	0.8	1.0	0.6	-0.2	1.7	2.9	2.6	-4.1	-4.1	-1.6	-0.8
Mean time to correctly identify matches	1.2	2.3	5.3	1.3	1.3	-1.7	-1.3	1.9	-0.6	-0.9	-2.0	2.3	1.5	1.8	0.0
Arm predicted mass (right)	1.2	6.1	17.1	-3.9	0.7	1.2	0.8	-0.4	1.8	2.9	2.7	-4.1	-4.1	-1.7	-0.7
Average weekly champagne plus white wine intake	1.2	1.7	6.3	1.3	0.4	-1.1	-1.8	0.3	-0.5	0.5	-1.0	2.5	1.6	1.6	1.1
Irritability	1.2	2.0	6.3	0.1	-1.2	2.5	1.5	-2.1	0.5	0.6	-0.4	1.4	-0.3	-1.9	1.6
Depression (Nagel 2018)	1.1	1.6	5.7	0.9	-0.3	1.1	0.6	-0.8	-1.4	-0.1	0.7	-2.0	-1.4	-1.2	-2.4
Alzheimer’s Disease (including proxy)	1.1	1.6	5.0	0.5	1.0	-2.1	-1.8	1.5	-1.5	0.7	-0.7	-0.2	0.9	2.2	-0.3
Coronary Artery Disease (CAD)	1.1	1.3	2.8	-0.7	-1.6	-1.5	-1.6	0.1	0.1	0.5	1.7	0.3	-1.1	1.4	-1.2
Crohns Disease (2012)	1.1	1.8	4.6	0.4	-0.9	-2.0	-1.6	0.4	-1.5	-0.7	-1.8	0.0	1.8	2.2	-0.1
Fasting Glucose	1.1	1.3	5.0	-0.8	0.1	-0.1	-0.5	0.0	2.2	2.0	1.1	0.5	0.0	0.6	2.0
Systolic Blood Pressure	1.1	5.5	11.5	2.0	-0.4	-3.4	-2.9	2.3	-0.8	-0.9	-2.7	2.8	3.1	3.3	0.8
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	5.0	-0.7	1.5	0.4	0.5	-0.0	1.7	0.6	0.8	1.2	0.7	-0.3	2.2
Medication: Atenolol	1.1	1.4	5.8	-1.5	0.7	0.7	0.6	-0.2	1.1	1.5	1.2	-2.4	-0.8	-1.0	0.9
High blood pressure (mother)	1.1	1.5	4.7	-0.3	2.2	-1.6	-2.0	0.6	-0.0	1.6	0.4	0.1	-0.7	1.7	-0.6
Qualifications: A levels/AS levels or equivalent	1.1	2.4	6.5	-1.0	-0.0	2.3	1.8	-2.5	0.5	1.2	1.1	0.5	-0.6	-1.7	2.5
Asthma	1.1	2.1	5.9	0.9	1.5	-1.6	-1.5	0.4	-1.2	-0.6	-2.4	1.0	2.4	1.6	0.2
Ever highly irritable/argumentative for 2 days	1.1	1.3	4.3	0.0	2.1	1.4	0.8	-1.4	-0.4	-0.8	-0.3	-0.6	-0.4	-1.6	-1.5
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	3.3	0.3	-0.1	-1.7	-1.8	1.8	1.0	1.0	-0.6	1.5	-0.8	1.5	0.1
Number of full brothers	1.1	1.4	6.2	-1.0	-0.9	0.9	0.5	-0.7	1.7	1.2	2.5	-0.1	-1.2	-0.9	0.5
Loneliness, isolation	1.1	1.5	6.0	-0.9	-2.4	0.4	0.3	0.1	0.0	0.4	1.6	-1.8	-1.9	-0.6	-1.1
Eye problems/disorders: Cataract	1.1	1.2	3.0	1.3	1.4	-0.7	0.5	1.7	-1.4	-1.7	-0.7	-0.1	1.3	0.5	0.4
Breast cancer (self-reported)	1.1	1.3	4.5	-0.5	2.1	-1.0	-1.2	1.3	0.1	1.6	-0.6	0.3	0.0	1.2	1.6
Arm fat-free mass (left)	1.1	5.5	15.1	-3.8	0.7	1.1	0.8	-0.2	1.7	2.6	2.4	-3.9	-3.9	-1.6	-0.9
Frequency of depressed mood in last 2 weeks	1.0	1.4	4.6	0.7	-0.7	1.2	0.5	-0.3	-0.8	0.2	1.2	-1.9	-1.5	-1.3	-2.1
Medication: Co-codamol	1.0	1.2	7.8	-0.6	-0.6	0.3	0.5	0.1	-0.7	0.1	0.4	-2.8	-1.4	-0.6	-1.4
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	8.1	1.4	1.8	-0.7	-1.0	0.8	-0.6	-0.2	-0.9	-0.4	-1.5	0.3	-2.8
Illnesses of mother	1.0	1.3	3.8	1.9	-1.2	0.0	0.2	0.1	-0.4	-2.0	-1.8	1.4	0.6	-0.0	-0.7
Gout (self-reported)	1.0	1.3	2.9	1.6	-0.4	-1.7	-1.4	1.5	-0.7	-0.4	-1.6	0.8	-0.1	1.4	-0.8
Leg fat percentage (right)	1.0	3.5	9.9	0.1	0.4	-2.7	-3.1	2.3	0.7	2.5	-0.5	1.0	1.2	2.9	1.3
Pulse wave peak to peak time	1.0	1.2	5.7	0.6	-1.3	-0.7	-0.8	0.0	-0.7	0.3	1.2	-1.0	-1.5	0.4	-2.4
Medication: Omeprazole	1.0	1.2	3.6	1.4	0.4	-1.1	-0.5	1.6	-0.8	-1.7	-0.5	-0.0	1.9	1.2	-0.2
Age at last live birth	1.0	1.4	6.4	0.5	-0.7	1.6	1.4	-2.5	-0.7	-1.0	0.4	1.0	-0.4	-1.5	-0.4
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	6.6	-0.9	2.6	0.9	0.7	-0.3	-0.4	0.1	0.5	-1.8	-0.6	-1.0	-0.8
Leg fat percentage (left)	1.0	3.5	10.2	-0.2	0.6	-2.8	-3.2	2.4	0.6	2.5	-0.3	0.7	1.0	2.9	1.1
Risk taking	1.0	1.4	4.1	-0.8	1.2	1.3	2.0	0.4	0.2	-0.3	0.7	-1.8	-1.6	-1.6	-0.2
Commuting to job workplace: Cycle	1.0	1.2	2.8	-0.1	-1.1	1.6	1.7	-1.3	1.1	-0.1	0.6	0.7	0.3	-1.4	1.3
Arm predicted mass (left)	1.0	5.0	14.5	-3.5	0.6	1.0	0.7	-0.2	1.4	2.4	2.4	-3.8	-3.8	-1.5	-1.2
Supplements: Zinc	0.9	0.9	6.9	-0.2	2.6	-0.3	-0.3	0.1	-0.0	0.1	-1.2	-0.9	1.2	0.3	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.5	5.5	0.9	0.2	-0.8	-1.0	1.4	-1.7	-0.2	-0.8	-1.8	-0.2	0.6	-2.3
Medication: Simvastatin	0.9	1.4	3.1	-1.6	1.7	0.3	0.3	0.2	1.7	1.1	0.5	-1.7	-1.8	-0.7	-0.0
Fluid intelligence score	0.9	1.8	7.4	1.5	-0.8	-0.1	0.0	-0.1	0.0	-1.1	-1.1	2.7	2.6	0.4	1.5
Pulse wave Arterial Stiffness index	0.9	1.1	5.0	-1.0	1.2	1.0	1.1	-0.1	0.8	-0.2	-0.9	0.6	0.9	-0.7	2.2
Age at first live birth	0.9	1.7	8.6	-0.3	-0.8	2.0	1.4	-2.9	-0.4	-0.8	0.2	0.7	-0.5	-1.8	-0.3
Ever had bowel cancer screening	0.9	1.0	2.5	-0.5	0.7	0.8	1.3	0.2	-1.6	-1.4	-0.6	-1.3	-0.6	-1.2	-1.0
Mineral and other dietary supplements	0.9	1.2	5.2	-1.8	0.0	0.6	0.7	-0.0	0.5	-0.0	1.3	-1.0	-2.3	-0.8	-1.1
Asthma (self-reported)	0.9	1.8	5.1	0.7	1.4	-1.6	-1.3	0.5	-1.4	-0.7	-2.3	0.7	2.1	1.5	0.1
Number of self-reported non-cancer illnesses	0.9	1.6	4.3	0.4	2.1	-1.7	-1.8	1.3	-0.2	0.7	-1.9	-0.6	0.7	1.5	-0.2
Hearing aid user	0.9	1.1	3.6	0.4	0.5	1.3	1.4	-1.9	0.5	0.0	0.7	-1.1	0.9	-1.4	0.8
Supplements: Calcium	0.9	1.0	6.4	-0.5	2.5	-0.6	-0.6	1.6	-0.0	1.0	-0.5	-0.6	-0.2	0.6	0.7
Mean Putamen Volume	0.8	0.9	3.2	-0.2	-1.8	-0.6	-0.6	0.3	0.5	1.2	-0.4	1.4	0.4	0.7	1.4
Triglycerides	0.8	1.3	4.4	0.5	-1.1	-0.0	-0.1	1.1	-1.4	1.2	1.0	-2.1	-1.4	-0.1	-1.4
Blood Red Count	0.8	7.5	12.8	3.6	1.6	-2.7	-1.9	3.0	-2.4	-3.6	-3.5	2.8	2.7	2.9	-1.1
Waist Hip Ratio (WHR)	0.8	3.4	9.0	-2.0	-0.4	2.4	1.8	-1.4	1.1	1.7	1.7	-1.9	-3.0	-2.4	1.0
Medication for hormone replacement therapy	0.8	0.9	4.6	-0.2	0.2	0.7	0.8	-0.9	1.0	0.5	-0.3	1.3	0.7	-0.4	2.2
Fed-up feelings	0.8	1.4	4.3	1.8	0.9	-1.1	-1.4	2.1	-0.3	-0.1	-1.2	1.1	1.0	1.3	-0.2
Trunk fat mass	0.8	3.3	12.5	-2.8	0.7	-0.4	-1.0	1.1	2.5	3.5	1.7	-0.8	-2.3	0.2	1.4
Hair/balding pattern: Pattern 2	0.8	1.0	5.2	0.1	-0.7	0.5	0.2	-0.0	0.9	0.5	-0.4	2.1	0.3	-0.1	2.3
Had menopause	0.8	0.9	2.9	0.9	1.2	-0.5	-1.1	0.3	0.3	1.4	-1.7	0.3	1.0	0.8	0.9
Had other major operations	0.8	1.0	5.4	-0.6	-0.1	1.2	0.8	-2.3	0.6	-0.3	0.1	1.1	1.0	-1.1	0.2
Weight	0.8	4.0	10.9	-3.2	0.4	0.5	-0.0	0.3	1.9	3.2	2.5	-2.3	-3.3	-0.8	0.3
Birth weight of first child	0.8	1.5	3.4	-1.5	0.6	1.3	1.4	-1.8	1.2	-0.1	1.1	-0.6	-1.8	-1.5	-0.5
Pulse wave reflection index	0.8	1.0	5.5	-0.3	0.8	-0.2	0.3	0.6	1.0	-0.8	-1.1	0.6	2.3	0.3	1.4
Medication: Amlodipine	0.8	1.2	3.3	0.6	-1.8	0.8	1.2	-1.8	0.7	-1.3	1.0	-0.2	0.4	-1.1	-0.8
Neck or shoulder pain in last month	0.8	1.1	2.4	0.8	1.1	-1.5	-1.5	1.0	-0.2	-0.4	-1.4	0.3	1.0	1.3	-1.1
Knee pain experienced in last month	0.8	1.2	3.9	1.2	1.1	-1.2	-1.8	0.4	-0.9	-0.3	-0.7	0.0	0.4	1.2	-2.0
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	4.9	-0.5	-1.1	1.4	1.5	-1.0	0.3	0.4	1.3	-1.4	-2.2	-1.7	-1.2
Ever taken oral contraceptive pill	0.8	0.8	2.9	0.4	-1.3	-1.3	-1.1	0.3	0.7	-0.3	0.2	1.7	0.4	1.3	-0.1
Eye problems/disorders: Glaucoma	0.8	0.9	3.2	1.6	0.8	-0.2	-0.2	0.6	-0.7	-1.0	-1.6	0.6	1.8	0.1	0.3
Ever smoked	0.8	1.4	4.2	-0.4	0.2	1.7	2.0	-0.3	0.4	-0.1	1.8	-1.0	-1.2	-1.8	0.9
Pain experienced in last month	0.8	1.3	3.8	-1.3	-1.9	0.8	1.3	-0.9	0.4	-0.3	1.3	1.2	0.1	-0.6	1.8
Alzheimer’s Disease (in mother)	0.7	0.9	2.2	-1.2	0.3	-1.5	-0.9	0.3	-0.6	0.9	0.2	-1.4	0.7	1.3	0.6
Crohns Disease (2017)	0.7	1.5	3.5	0.6	-0.5	-1.4	-0.7	0.6	-1.5	-1.9	-1.8	-0.1	1.7	1.4	-0.7
Blood Platelet Count	0.7	8.0	36.1	3.8	-0.2	-0.9	0.3	0.0	-2.0	-3.3	-3.9	3.3	6.0	0.9	1.6
Allergy or Eczema	0.7	1.8	10.6	0.3	1.8	-0.0	0.4	1.1	-1.1	-1.6	-3.2	0.6	1.5	-0.1	-0.1
Type 2 Diabetes (T2D) (2018)	0.7	1.2	2.8	-0.1	1.0	-1.5	-1.4	1.2	0.3	1.5	-0.3	-0.3	0.6	1.5	1.7
Trunk fat percentage	0.7	2.9	10.9	-1.9	0.6	-1.2	-1.9	1.7	2.4	3.3	0.8	0.3	-1.3	1.2	1.7
Serious illness, injury or assault to yourself	0.7	0.9	2.9	-0.1	-0.1	-0.7	-1.2	0.3	0.9	1.4	-0.3	-0.7	-1.7	0.4	-1.3
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	2.4	-1.6	0.6	1.1	1.4	0.0	1.6	-0.6	-0.4	-0.4	-0.6	-1.4	0.3
Falls in the last year	0.7	0.9	2.2	-0.4	0.2	1.1	1.2	-0.2	1.3	-0.3	1.5	-1.3	-0.3	-1.3	-0.5
Happiness	0.7	0.8	2.0	-0.7	0.0	-0.5	-1.3	1.4	0.7	1.4	0.6	-0.3	-1.0	0.6	-1.0
Depression (self-reported)	0.7	0.8	2.1	1.2	1.5	-0.9	-1.4	0.4	0.3	0.1	-0.9	0.7	0.2	1.0	-1.1
Length of working week for main job	0.7	0.8	4.9	-0.1	0.6	-0.9	-0.7	2.2	-0.4	-0.2	-1.5	-0.1	0.1	0.7	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	5.0	1.9	-0.6	0.1	0.8	0.0	0.0	-2.2	-0.8	0.9	1.3	-0.0	-0.0
High blood pressure (siblings)	0.7	1.0	4.7	-0.4	-0.6	-0.6	-0.1	0.8	-0.2	-0.3	0.7	0.5	2.0	0.8	2.2
Body fat percentage	0.7	2.6	8.5	-1.3	0.6	-1.7	-2.3	1.9	1.7	2.9	0.4	0.5	-0.3	1.7	1.6
Exposure to tobacco smoke outside home	0.7	1.0	2.8	-1.2	0.7	0.4	0.6	1.7	1.3	0.5	0.5	-1.4	-1.3	-0.8	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.7	1.6	-0.5	-1.0	-0.9	0.8	-0.4	-0.1	-1.1	0.9	0.8	1.2	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.8	0.6	0.4	-1.0	-1.1	1.0	-0.7	0.1	-0.1	-1.3	1.0	1.2	-1.1
Whole body fat mass	0.7	3.1	12.2	-2.6	0.5	-0.6	-1.2	1.1	2.2	3.5	1.7	-0.9	-2.1	0.5	1.3
Fractured/broken bones in last 5 years	0.7	0.9	2.1	-0.8	-1.5	0.9	1.2	-0.9	0.5	-0.4	1.4	-1.2	0.5	-1.0	-0.0
Heart disease (siblings)	0.7	0.9	2.6	1.1	-0.3	-1.1	-0.7	0.7	0.1	-0.8	-0.6	1.6	1.5	1.0	0.7
HbA1C	0.6	0.6	4.6	0.3	-2.1	0.2	-0.1	-0.6	0.8	0.6	0.4	1.0	0.1	0.0	0.4
Vitamin and mineral supplements	0.6	0.8	2.2	-0.5	-0.8	0.8	0.9	-1.1	-0.2	-0.9	0.6	-0.4	-1.5	-0.8	-1.3
Relative age voice broke	0.6	0.9	4.0	-0.4	0.5	-0.5	-1.2	0.5	1.2	2.0	0.5	-0.5	-1.3	0.6	-0.1
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	2.4	-1.4	1.1	0.4	0.5	0.4	1.5	-0.1	0.8	-0.4	-0.7	-0.6	0.2
Past tobacco smoking	0.6	1.1	3.1	0.4	0.0	-1.5	-1.8	0.2	-0.9	0.5	-1.7	0.7	0.9	1.4	-1.0
Medication: Ramipril	0.6	0.8	2.2	-1.1	-0.0	-0.3	-0.8	-0.1	1.5	1.5	1.1	-0.0	0.2	0.5	1.4
Illnesses of siblings	0.6	0.9	3.8	-0.3	-0.0	1.1	0.9	-0.8	-0.1	0.1	-0.1	-0.4	-1.9	-1.2	-1.6
Hair/balding pattern: Pattern 3	0.6	0.8	2.9	-1.2	0.1	0.2	0.4	-1.4	0.7	0.8	1.5	-1.7	0.1	-0.5	0.3
Prospective memory result	0.6	0.8	2.2	-1.1	0.7	0.8	1.1	-0.2	0.5	-0.2	1.5	-1.1	-1.1	-0.9	0.2
Medication: Ventolin 100micrograms inhaler	0.6	0.7	1.3	0.7	0.8	-1.1	-1.1	-0.1	-0.8	-0.7	-1.0	-0.1	1.0	0.9	-0.9
Shortness of breath walking on level ground	0.6	0.7	3.0	0.9	0.7	-0.5	-0.7	0.5	-1.0	-0.6	-1.4	-0.1	0.4	0.3	-1.7
Medication for pain relief, constipation, heartburn	0.6	1.0	3.3	0.6	-1.8	-0.1	0.1	-1.3	-1.7	-1.1	-0.0	-0.1	-0.2	0.0	-1.4
Heart disease (mother)	0.6	0.7	2.4	0.5	-1.1	0.2	-0.6	-1.3	-0.0	1.5	0.5	0.1	1.2	0.0	0.5
Number of full sisters	0.6	0.7	1.8	-0.9	0.7	-0.8	-1.0	0.0	1.3	1.0	0.8	0.8	-0.5	0.9	0.5
Illnesses of father: Heart disease	0.6	0.8	3.6	-0.0	0.2	-0.4	-0.2	0.1	0.4	-0.4	-1.9	1.3	1.7	0.5	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	2.3	0.7	1.2	0.5	1.0	-0.0	-1.1	-1.5	0.2	-0.0	0.3	-0.6	-0.8
Illnesses of father: None of the above (group 1)	0.6	0.7	2.2	1.1	1.5	-1.0	-0.7	1.1	-1.2	-0.3	-0.2	-0.2	0.3	0.9	-0.6
Arm fat mass (left)	0.6	2.3	9.2	-2.5	0.6	-0.5	-1.0	0.9	1.9	3.0	1.3	-0.9	-1.5	0.3	1.1
Financial situation satisfaction	0.6	0.8	2.3	-0.6	-0.0	-0.7	-1.1	1.1	1.0	0.8	0.5	-0.9	-1.0	0.5	-1.5
Medication: Paracetamol	0.6	1.0	3.9	0.9	0.3	-0.8	-0.4	1.6	-0.5	-0.8	-1.2	0.3	2.0	0.8	0.4
Illnesses of father: High blood pressure	0.6	0.7	1.7	-0.3	-0.7	0.9	0.5	-1.2	0.8	1.0	1.3	-0.8	0.0	-0.6	1.1
Myopia	0.6	0.9	1.8	0.8	-0.5	-1.1	-1.3	0.1	-1.1	0.5	-1.2	-0.5	0.7	1.2	-1.1
Irritable Bowel Disease (IBD)	0.5	1.3	3.5	0.3	0.5	-1.7	-1.3	1.1	-0.6	-1.0	-1.9	-0.7	0.6	1.5	-1.1
Ulcerative Colitis (UC)	0.5	1.0	2.6	0.0	1.2	-1.5	-1.6	1.3	0.4	0.3	-1.3	-0.7	-0.0	1.4	-0.3
Major Depression (MDD)	0.5	0.6	2.4	1.2	0.3	-0.4	0.1	-0.1	-0.9	-1.2	-0.7	0.5	1.6	0.6	0.2
Breast Cancer	0.5	1.1	8.1	-0.6	0.8	0.9	0.8	-0.5	0.4	1.1	-0.2	0.9	0.9	-0.3	2.9
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.5	-1.6	-0.3	-0.4	0.3	0.6	-0.5	0.7	1.2	-1.0	0.6	0.7	0.4
Ulcerative Colitis	0.5	0.7	1.9	-0.1	1.4	-0.5	-1.3	0.1	1.1	1.2	-1.1	-0.0	-0.4	0.8	0.2
Number of treatments/medications taken	0.5	1.0	5.2	0.1	2.3	-0.7	-0.7	1.2	0.2	0.4	-0.3	-1.2	1.2	0.6	0.4
Relative age of first facial hair	0.5	1.0	4.3	-1.0	1.4	1.0	0.1	-0.3	1.0	1.4	0.8	-0.1	-2.1	-0.7	-0.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.8	0.7	-0.2	-0.4	-1.2	0.8	-0.8	1.4	-0.5	-0.8	-0.3	0.5	-0.9
Medication: Metformin	0.5	0.6	3.6	-0.4	0.8	-0.2	-0.2	0.0	-0.0	1.3	-0.2	-0.4	1.1	0.3	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	1.4	-0.1	-1.2	1.0	0.6	-1.1	-0.2	0.4	1.1	-0.8	-1.2	-0.9	-0.5
Stomach or abdominal pain in last month	0.5	0.6	3.0	0.6	1.1	-0.4	-0.6	0.9	-0.5	-0.3	-0.8	-0.0	-0.4	0.1	-1.7
Waist circumference	0.5	1.7	8.4	-1.7	0.5	-0.3	-1.1	0.3	1.4	2.9	1.1	-1.0	-1.6	0.2	0.8
Ever unenthusiastic/disinterested for a whole week	0.5	0.7	2.5	0.8	-0.3	0.9	0.6	-1.3	0.0	-0.8	-0.7	1.6	0.4	-0.8	0.2
Financial difficulties in last 2 years	0.5	0.7	3.8	0.6	0.4	-0.5	-0.6	0.7	-0.5	-0.0	0.7	-0.5	-1.2	0.1	-2.0
Worrier / anxious feelings	0.5	0.9	3.6	1.5	0.3	-0.5	-0.6	1.6	-0.1	-0.4	-1.9	0.9	0.0	0.5	-0.5
Medication: Lansoprazole	0.5	0.5	1.4	0.6	0.9	0.8	1.2	-0.0	-0.4	-0.8	-0.0	0.0	1.1	-0.7	0.9
Arm fat mass (right)	0.5	2.1	8.1	-2.4	0.2	-0.6	-1.0	1.1	1.6	2.9	1.4	-1.0	-1.5	0.5	0.9
Breastfed as a baby	0.5	0.7	2.2	-0.5	1.2	0.2	-0.1	-1.0	0.5	0.9	0.8	1.0	-0.3	0.2	1.5
Hair/balding pattern: Pattern 4	0.5	1.1	2.8	0.4	1.7	-0.7	-0.4	1.7	-1.7	-0.7	-0.8	-1.2	0.4	0.5	-1.0
Qualifications: O levels/GCSEs or equivalent	0.5	0.9	2.1	0.0	-0.6	1.4	1.1	-1.4	-0.7	0.6	1.1	0.2	0.3	-0.9	1.2
Medication: Paracetamol	0.5	0.9	2.5	1.3	0.4	-0.6	-0.1	1.6	-0.6	-1.2	-0.9	0.7	1.5	0.7	0.0
Comparative body size at age 10	0.5	1.5	4.4	1.1	-2.1	-0.9	-0.9	-0.2	-2.0	-0.2	0.5	-1.0	-0.5	0.7	-2.0
Leg fat mass (right)	0.5	1.8	8.1	-1.5	0.7	-1.1	-1.6	1.4	1.3	2.8	1.0	-0.4	-1.0	1.0	1.0
Suffer from ‘nerves’	0.5	0.8	1.6	0.1	0.4	1.2	0.4	-0.9	1.3	1.2	0.5	0.7	-1.1	-0.8	1.0
Family relationship satisfaction	0.5	0.6	2.9	-0.9	-0.8	0.7	0.6	-0.0	0.1	0.6	1.7	0.5	-0.2	-0.4	1.2
Medication: Aspirin	0.5	0.6	2.8	-1.2	0.9	0.2	0.1	-0.2	1.7	0.7	-0.0	-0.9	-0.8	-0.4	0.5
Arm fat percentage (left)	0.5	1.9	6.7	-1.4	0.5	-1.2	-1.7	1.3	1.4	2.6	0.5	0.6	-0.0	1.3	1.8
Handedness (chirality/laterality): Left-handed	0.5	0.5	1.1	0.7	0.4	1.1	1.1	-0.9	-0.3	-0.6	-0.3	0.4	0.7	-0.9	0.9
Long-standing illness, disability or infirmity	0.5	0.8	3.1	0.6	1.5	-1.2	-0.9	1.8	-0.8	0.4	-0.1	-0.4	-0.2	1.0	0.3
Diabetes diagnosed by doctor	0.5	0.8	2.8	-0.2	1.2	-1.0	-1.0	0.4	0.2	1.7	-0.2	-0.4	0.0	1.0	1.4
Medication: Aspirin	0.5	0.6	2.5	-1.1	0.8	-0.1	-0.3	-0.3	1.6	0.9	-0.3	-1.0	-0.7	-0.0	0.7
Miserableness	0.5	0.9	3.9	2.0	-1.2	0.8	0.5	-0.1	0.0	-1.2	-1.0	0.9	0.3	-0.8	-0.5
Alcohol drinker status: Never	0.5	0.5	2.2	0.5	0.5	0.1	0.6	0.8	-0.5	-1.5	-1.1	0.1	1.1	-0.2	-0.3
Unable to work because of sickness or disability	0.5	0.7	4.3	-0.5	-2.1	-0.5	-0.3	1.4	0.5	0.8	0.3	-0.4	-0.5	0.3	0.3
Leg fat mass (left)	0.5	1.9	7.5	-1.5	0.7	-1.3	-1.6	1.7	1.1	2.7	0.9	-0.5	-0.9	1.2	0.9
Bipolar Disorder (2018)	0.4	0.7	2.9	0.5	-0.3	1.2	0.9	-1.7	-0.0	-1.0	0.2	0.9	0.7	-0.8	0.2
Neuroticism (Nagel 2018)	0.4	0.9	3.8	2.0	0.3	0.1	-0.2	0.9	-0.9	-0.9	-1.3	0.4	-0.3	-0.0	-1.5
Lupus	0.4	0.6	1.6	0.7	-1.1	-0.8	-0.9	-0.5	-0.8	-0.4	0.1	0.4	0.6	0.8	-1.3
Rheumatoid Arthritis	0.4	0.5	3.2	0.6	0.4	-0.5	-0.5	0.6	-0.8	-0.2	-0.7	-0.6	-0.3	0.4	-1.8
Impedance of leg (right)	0.4	2.1	4.4	2.1	-0.4	-1.8	-1.9	1.4	-0.1	-0.3	-1.4	2.1	1.2	2.0	-0.0
Average weekly fortified wine intake	0.4	0.5	3.0	0.2	0.2	-0.0	-0.4	-0.8	0.9	0.0	-0.5	1.7	-0.1	0.2	0.6
Taking other prescription medications	0.4	0.5	2.9	0.5	1.7	-0.3	-0.5	0.7	0.4	0.1	-0.6	-0.9	-0.1	0.1	-1.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	3.9	-0.2	2.0	0.1	0.0	-0.1	-0.3	0.6	-0.5	-0.4	0.1	-0.2	0.3
Qualifications: CSEs or equivalent	0.4	0.5	1.6	0.5	-1.3	-0.4	-0.6	0.3	-0.2	0.3	0.7	-1.0	-0.6	0.2	-1.1
Multivitamins +/- minerals	0.4	0.5	1.3	0.6	0.6	-0.6	-0.7	1.1	-0.3	0.7	-0.2	0.4	1.1	0.8	0.6
Body mass index (BMI)	0.4	1.5	4.2	-0.7	0.4	-1.8	-2.0	1.6	0.5	2.0	-0.0	-0.1	0.4	1.8	0.6
Impedance of leg (left)	0.4	1.7	4.3	1.4	-0.0	-1.9	-2.1	1.7	0.2	0.1	-0.9	1.5	0.6	2.0	-0.2
Diabetes (self-reported)	0.4	0.6	3.0	-0.4	0.8	-0.3	-0.5	-0.2	0.4	1.7	0.4	-0.8	-0.1	0.4	1.4
Hip circumference	0.4	1.7	8.5	-1.4	-0.1	-0.9	-1.6	0.6	1.2	2.9	1.2	-0.2	-1.4	0.8	0.5
Time employed in main current job	0.4	0.5	2.4	-0.3	-0.1	0.4	1.0	-0.4	-0.6	-0.3	0.3	1.6	-0.7	-0.2	1.0
Alcohol intake versus 10 years previously	0.4	0.6	2.6	-0.9	1.1	0.6	-0.0	0.1	0.9	1.6	0.1	-0.4	-0.5	-0.6	0.7
Noisy workplace	0.4	0.5	1.8	-0.1	1.1	-0.5	0.0	0.9	-0.2	-1.3	-0.7	-0.7	0.4	0.3	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	1.1	0.3	-0.6	-0.8	-0.3	1.0	-1.0	-1.0	-0.6	0.9	0.2	0.6	-0.1
Medication: Cholesterol lowering	0.4	0.6	2.1	-1.4	0.7	-0.0	0.1	0.3	0.9	0.5	0.6	-1.3	-1.1	-0.3	-0.4
Exposure to tobacco smoke at home	0.4	0.5	1.7	-0.2	1.1	0.6	0.3	0.4	0.6	0.9	1.3	-0.5	-0.5	-0.5	0.1
Tense / ‘highly strung’	0.4	0.6	1.8	-0.4	-1.1	1.2	1.4	-0.0	0.3	-0.6	0.2	-1.1	-0.1	-1.1	0.1
Qualifications: College or University degree	0.4	1.4	9.4	0.5	-0.6	0.3	0.0	0.1	0.2	0.4	-1.1	3.1	0.8	0.3	2.2
Migraine (self-reported)	0.4	0.5	3.1	-0.2	-0.3	0.2	-0.1	0.1	0.9	1.7	-0.2	0.1	-0.1	-0.2	1.3
Medication: Ibuprofen	0.4	0.5	1.9	-0.3	0.5	-0.3	-0.4	0.2	0.1	0.8	0.3	1.4	0.6	0.6	1.4
Pulse rate, automated reading	0.4	1.3	4.6	0.5	2.1	0.2	0.4	1.1	-1.6	-1.5	-0.5	-1.6	0.4	-0.3	-1.0
Alcohol intake frequency.	0.4	0.9	2.5	-0.8	1.3	0.7	0.5	0.3	0.4	1.3	0.7	-1.6	-1.2	-0.9	-0.1
Overall health rating	0.4	0.8	2.3	0.1	0.9	-0.3	-0.7	0.4	0.9	1.2	0.9	-0.7	-1.5	-0.2	-1.3
Illnesses of siblings: Diabetes	0.4	0.5	1.5	-0.5	0.9	0.1	-0.3	-0.3	1.2	1.2	1.2	-0.4	-0.4	0.0	0.7
Tinnitus: Yes, now most or all of the time	0.4	0.5	2.1	-0.6	-0.5	-0.2	-0.1	1.4	1.1	0.6	-0.9	-0.5	-0.3	0.2	0.6
Medication: Lisinopril	0.4	0.5	3.3	0.5	-1.8	0.4	0.3	-1.1	-0.3	-0.2	-0.0	0.2	0.5	-0.3	-0.2
Basal cell carcinoma (self-reported)	0.4	0.5	3.2	0.1	-1.8	0.1	-0.2	-1.0	-0.7	0.6	0.4	-0.5	0.1	-0.1	-0.3
Depressed Affect (Nagel 2018)	0.3	0.6	2.0	1.2	0.0	0.1	-0.4	0.8	-0.2	0.3	-0.4	-0.5	-1.4	-0.2	-1.4
Ovarian Cancer	0.3	0.4	1.6	0.4	1.2	-0.1	0.3	1.3	-0.4	-0.5	-0.6	0.9	0.2	-0.1	-0.5
LDL Cholesterol	0.3	0.5	1.7	1.0	-0.4	0.0	0.2	-0.6	-1.2	-1.1	-0.5	-0.2	0.0	-0.2	-1.3
Schizophrenia (2014)	0.3	0.8	2.0	-0.5	-1.0	0.7	0.8	-0.8	0.2	-0.6	1.4	-1.1	-1.4	-0.6	-0.4
BMI	0.3	1.6	5.2	-0.6	0.3	-1.5	-1.9	1.5	0.8	2.3	0.3	-0.6	0.3	1.6	0.9
Lung FEV1/FVC ratio	0.3	1.5	5.1	-0.4	1.1	-1.3	-1.3	0.8	0.3	0.3	2.2	-1.8	0.3	1.1	-1.6
Chronotype (morning person)	0.3	0.6	2.0	1.2	-0.3	0.7	0.6	-0.7	0.3	-0.8	0.4	0.7	1.4	-0.8	0.4
Hayfever, allergic rhinitis or eczema	0.3	0.7	4.3	-0.2	1.4	0.4	0.4	1.0	-0.6	-0.5	-2.1	0.0	0.9	-0.2	0.3
Supplements: Glucosamine	0.3	0.4	1.9	0.1	-0.4	0.6	0.3	-1.1	0.4	0.4	-0.2	0.5	1.4	-0.2	0.9
Qualifications: None of the above	0.3	0.6	2.2	-0.1	-0.8	-0.3	-0.2	1.5	0.9	-0.0	0.2	-1.1	-1.0	-0.1	-1.1
Allergy	0.3	0.8	4.5	0.4	-1.7	0.3	0.3	-0.4	0.2	0.4	2.1	0.3	-0.9	-0.1	0.1
Neuroticism score	0.3	0.6	2.9	1.7	-0.7	0.4	-0.1	0.3	-0.0	-0.5	-1.2	1.2	0.5	-0.1	0.1
Arm fat percentage (right)	0.3	1.3	3.8	-1.0	0.1	-1.3	-1.6	1.5	0.9	1.9	0.3	0.6	0.1	1.3	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	2.0	-0.1	1.0	0.3	0.2	-0.4	0.3	0.6	0.4	1.4	0.3	-0.1	1.1
Impedance of arm (left)	0.3	1.2	3.8	-0.1	-0.3	1.1	1.1	-0.6	1.5	0.1	0.6	1.9	-0.8	-1.0	1.8
Wheeze or whistling in the chest in last year	0.3	0.6	2.7	-0.9	1.6	0.7	0.3	-0.7	0.2	0.0	-0.5	-1.2	0.2	-0.9	-0.3
Number of children fathered	0.3	0.3	1.2	0.3	-0.5	-0.7	-0.8	-0.4	1.1	0.6	-0.2	0.0	0.4	0.6	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	2.3	0.1	-0.4	0.1	0.5	-0.9	-1.5	-0.8	0.0	-0.5	0.3	0.1	-0.5
Medication: Seretide 50 evohaler	0.3	0.4	0.9	-0.2	1.0	0.6	1.0	-0.6	0.5	-0.7	-0.0	-0.7	0.1	-0.8	-0.2
Qualifications: nursing, teaching	0.3	0.5	1.0	-0.0	0.2	0.9	0.6	-0.9	-0.6	0.7	1.0	-0.4	-0.8	-0.6	0.7
Back pain experienced in last month	0.3	0.5	1.9	0.9	0.7	-0.1	-0.9	-0.3	-0.1	1.4	-0.3	-1.1	-0.2	0.3	-0.4
Medication: Gliclazide	0.3	0.4	2.2	0.3	0.6	0.3	0.3	-0.3	-1.5	0.8	-0.2	-0.6	0.3	-0.2	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.5	2.2	-0.6	-0.6	0.5	0.6	-0.2	0.9	-0.4	0.4	-1.5	-0.9	-0.7	-0.8
High cholesterol (Self-reported)	0.3	0.6	2.5	-0.1	1.6	0.5	1.1	0.4	0.6	-1.0	-0.4	-0.5	-0.9	-0.6	-0.2
Medication: Atorvastatin	0.3	0.3	1.4	0.4	0.7	-0.1	-0.1	0.3	-0.3	-0.8	-0.9	-0.1	0.3	0.0	-1.2
Age started oral contraceptive pill	0.3	0.4	1.5	0.2	1.2	-0.4	-0.5	-0.3	-0.1	-0.1	-0.6	0.8	0.9	0.6	0.2
Cholesterol lowering medication	0.3	0.4	1.7	-0.1	1.3	-0.8	-0.6	0.0	1.1	0.2	-0.4	0.6	-0.1	0.6	0.2
Alcohol drinker status: Previous	0.3	0.4	1.5	0.1	0.5	0.1	0.4	0.8	0.4	-0.2	1.0	-1.2	-0.8	-0.3	-0.5
Bipolar Disorder or Schizophrenia	0.2	0.4	1.3	0.0	-0.9	0.6	0.5	-1.0	-0.2	-1.1	0.8	-0.3	-0.3	-0.3	-0.3
Schizophrenia (2018)	0.2	0.4	1.1	-0.5	-1.0	-0.2	-0.1	0.2	-0.2	-0.7	0.9	-1.1	-0.9	0.3	-0.5
Body Mass Index (BMI) (2010)	0.2	0.3	0.9	0.9	-0.0	-0.1	0.2	0.9	-0.5	-0.7	0.1	-0.7	0.8	0.2	-0.6
HDL Cholesterol	0.2	0.4	3.4	-0.5	-0.4	-0.2	0.7	0.3	0.2	-1.8	0.1	0.2	-0.0	-0.1	0.4
Neuroticism (2016)	0.2	0.3	1.4	0.4	0.3	-0.0	-0.4	-0.2	-0.5	1.2	-0.3	-0.5	-0.7	0.2	-0.9
Blood Eosinophil Count	0.2	1.6	3.8	0.7	0.8	-1.7	-1.4	1.7	-0.5	-0.4	-1.8	0.0	2.0	1.6	-0.2
Neuroticism	0.2	0.5	1.3	1.1	0.8	1.2	0.7	-0.6	-0.0	-0.3	-0.6	0.3	-0.3	-1.0	-0.4
Ever had hysterectomy (womb removed)	0.2	0.2	0.6	0.3	0.1	0.7	0.2	-0.4	0.4	0.8	0.5	-0.5	0.3	-0.8	0.0
High blood pressure	0.2	0.5	3.7	0.9	0.1	-0.1	-0.0	-0.1	-0.1	-0.0	-0.6	-0.3	1.9	0.1	1.1
Chronic bronchitis/emphysema (father)	0.2	0.2	0.7	-0.0	-0.8	-0.5	-0.2	0.8	-0.5	-0.1	0.2	0.2	-0.1	0.4	0.4
Impedance of arm (right)	0.2	0.8	4.2	0.7	-0.5	0.9	1.0	-0.0	0.6	-0.6	0.1	2.1	-0.5	-0.8	1.0
Number of live births	0.2	0.3	1.3	1.1	0.2	-0.4	-0.5	0.7	-1.0	0.4	-0.1	-0.3	0.3	0.2	-0.4
Pulse rate	0.2	0.4	1.3	-0.4	-0.0	0.2	0.1	0.1	-1.1	-0.4	-0.3	-0.9	-1.1	-0.3	-0.9
Headache pain in last month	0.2	0.4	2.5	-0.5	0.4	0.7	0.2	0.1	1.6	0.6	0.2	0.3	-0.1	-0.7	0.0
Worry too long after embarrassment	0.2	0.3	1.4	0.9	-0.6	0.0	0.0	0.4	-0.1	-0.8	-1.2	0.3	0.6	0.1	0.1
Medication: Blood pressure	0.2	0.4	2.5	-0.3	-0.7	-0.1	-0.3	-0.2	0.4	1.1	0.1	0.6	0.3	0.1	1.6
Leg pain on walking	0.2	0.2	1.1	0.1	1.1	0.5	-0.1	-0.0	0.4	0.8	0.2	0.3	-0.5	-0.5	-0.3
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.7	-0.6	-0.1	0.3	0.8	-0.5	-0.1	-0.6	0.1	-0.4	0.6	-0.4	0.5
Hypertension (Self-reported)	0.2	0.5	3.6	0.6	0.4	-0.1	0.0	-0.0	0.5	0.1	-0.5	-0.4	1.9	0.0	1.2
Smoking status: Previous	0.2	0.4	1.4	0.8	0.1	0.3	0.6	0.5	0.4	-1.2	0.4	0.8	0.3	-0.1	0.7
Medication for cholesterol	0.2	0.3	2.3	0.1	-1.5	0.1	-0.0	0.4	-1.0	-0.2	0.1	0.3	-0.3	0.0	-0.3
Osteoarthritis (self-reported)	0.2	0.3	0.9	-0.3	-0.5	-0.0	-0.3	-0.1	1.0	0.9	0.8	-0.3	-0.4	-0.1	-0.2
Wears glasses or contact lenses	0.2	0.2	0.6	0.6	-0.1	0.0	0.3	0.1	-0.7	-0.6	-0.3	0.3	0.8	0.4	0.6
Medication: Blood pressure	0.2	0.3	2.0	-0.0	0.7	-0.5	-0.6	0.2	0.5	0.7	0.1	-1.4	0.3	0.2	-0.4
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.5	-0.7	0.7	-0.1	0.5	-0.6	0.3	-0.2	0.3	-0.7	0.6	-0.0	0.7
Ever depressed for a whole week	0.2	0.3	0.7	-0.0	0.4	0.7	0.1	-0.4	0.8	0.7	-0.0	0.3	-0.4	-0.6	0.7
Worry (Nagel 2018)	0.1	0.3	0.7	0.5	0.5	0.8	0.4	0.1	0.8	0.1	-0.5	0.7	-0.4	-0.5	0.1
Cardiovascular Disease	0.1	0.4	1.1	0.7	0.1	-1.0	-0.7	1.0	0.7	-0.3	-0.1	-0.3	0.7	0.6	-0.5
Tanning	0.1	1.5	4.5	0.9	0.2	1.3	2.0	-1.2	-0.4	-2.1	1.4	-0.4	0.3	-1.5	-1.1
Age when periods started (menarche)	0.1	0.3	0.9	0.7	0.2	0.3	0.7	-0.0	-0.8	-1.0	0.6	-0.4	0.7	-0.3	-0.2
Nervous feelings	0.1	0.3	0.8	0.4	0.1	0.6	0.5	0.1	0.6	-0.2	-0.7	0.9	-0.1	-0.3	0.7
Medication: Allopurinol	0.1	0.1	0.7	0.4	-0.3	-0.2	-0.0	0.4	-0.0	0.1	-0.9	-0.3	-0.2	0.1	0.3
Mood swings	0.1	0.2	1.0	1.0	-0.1	0.4	-0.1	0.4	0.6	0.6	0.6	-0.2	-0.1	-0.2	-0.0
Mother’s age at death	0.1	0.1	0.5	0.1	0.1	0.1	-0.0	-0.4	-0.1	0.3	0.4	-0.7	-0.1	0.1	0.0
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.4	0.4	0.4	0.2	-0.0	0.6	0.1	0.3	-0.2	-0.7	-0.4	-0.4	-0.4
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.1	0.0	0.1	0.3	0.3	-0.3	-0.6	-0.8	-0.0	0.6	-0.9	-0.2	-1.0
Impedance of whole body	0.1	0.7	4.3	0.9	-0.2	-0.5	-0.6	0.7	0.8	0.0	-0.5	2.1	-0.1	0.6	0.8
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Medication for cholesterol, blood pressure or diabetes	0.0	0.1	0.2	0.2	0.4	0.4	0.2	-0.4	-0.2	-0.1	0.1	0.1	0.0	-0.1	-0.2

Hub : Genes

TULP4

Models

Trait associations