Best TWAS P=9.63e-21 · Best GWAS P=3.29e-20 conditioned to 5.47e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | GSDMC | 0.03 | 0.01 | blup | 57 | 0.02 | 1.4e-02 | -8.5 | -7.7 | 1.6e-14 | 0.48 | 0.07 | 0.08 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | GSDMC | 0.05 | 0.06 | lasso | 7 | 0.05 | 1.5e-10 | -8.5 | -8.8 | 1.8e-18 | 0.67 | 0.52 | 0.48 | FALSE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | GSDMC | 0.21 | 0.14 | blup | 57 | 0.15 | 1.2e-07 | -8.2 | -8.6 | 9.5e-18 | 0.74 | 0.34 | 0.62 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | GSDMC | 0.13 | 0.08 | lasso | 7 | 0.09 | 5.0e-06 | -7.8 | -7.3 | 2.4e-13 | 0.45 | 0.53 | 0.14 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | GSDMC | 0.25 | 0.30 | lasso | 5 | 0.32 | 4.6e-36 | -8.5 | -8.4 | 3.7e-17 | 0.58 | 0.63 | 0.37 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | GSDMC | 0.09 | 0.03 | enet | 5 | 0.06 | 7.0e-08 | -7.8 | -6.6 | 5.4e-11 | 0.43 | 0.66 | 0.26 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | GSDMC | 0.16 | 0.14 | blup | 57 | 0.15 | 6.3e-17 | -7.8 | -7.5 | 8.0e-14 | 0.48 | 0.95 | 0.05 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GSDMC | 0.03 | 0.02 | blup | 57 | 0.02 | 1.4e-03 | -8.5 | -9.3 | 9.6e-21 | 0.66 | 0.04 | 0.66 | TRUE |
| 9 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | GSDMC | 0.21 | 0.05 | blup | 57 | 0.06 | 1.2e-02 | -8.2 | -6.3 | 2.2e-10 | 0.29 | 0.03 | 0.06 | FALSE |