[Hub]/) : Traits : Forced vital capacity (FVC), Best measure :

chr10:76,664,253-80,383,574

Best TWAS P=2.35e-08 · Best GWAS P=1.23e-10 conditioned to 0.00025

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland DLG5 0.22 0.14 lasso 6 0.11 8.5e-05 -4.8 -5.6 2.6e-08 -0.04 0.02 0.96 TRUE
2 GTEx Brain Cortex C10orf11 0.32 0.15 lasso 8 0.21 1.4e-06 5.2 -5.6 2.3e-08 0.77 0.37 0.58 TRUE
3 GTEx Muscle Skeletal C10orf11 0.11 0.13 lasso 3 0.12 5.1e-12 5.2 -5.5 3.2e-08 0.73 0.80 0.20 FALSE
4 GTEx Ovary RP13-39P12.3 0.42 0.29 lasso 5 0.33 7.5e-09 -4.9 -5.2 2.4e-07 -0.01 0.02 0.97 FALSE
5 ROSMAP Brain Pre-frontal Cortex C10orf11 0.20 0.23 lasso 4 0.23 1.1e-29 5.2 -5.5 3.4e-08 0.69 0.80 0.20 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma DLG5 0.08 0.03 blup 116 0.06 2.1e-04 4.3 -5.2 2.2e-07 -0.07 0.05 0.90 FALSE