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Forced vital capacity (FVC), Best measure
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chr10:76,664,253-80,383,574
Best TWAS P=2.35e-08 · Best GWAS P=1.23e-10 conditioned to 0.00025
76.5M
77M
77.5M
78M
78.5M
79M
79.5M
80M
80.5M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Brain Cortex
C10orf11
0.32
0.15
lasso
8
0.21
1.4e-06
5.2
-5.6
2.3e-08
0.77
0.37
0.58
TRUE
1
GTEx
Adrenal Gland
DLG5
0.22
0.14
lasso
6
0.11
8.5e-05
-4.8
-5.6
2.6e-08
-0.04
0.02
0.96
TRUE
3
GTEx
Muscle Skeletal
C10orf11
0.11
0.13
lasso
3
0.12
5.1e-12
5.2
-5.5
3.2e-08
0.73
0.80
0.20
FALSE
5
ROSMAP
Brain Pre-frontal Cortex
C10orf11
0.20
0.23
lasso
4
0.23
1.1e-29
5.2
-5.5
3.4e-08
0.69
0.80
0.20
FALSE
6
The Cancer Genome Atlas
Colon Adenocarcinoma
DLG5
0.08
0.03
blup
116
0.06
2.1e-04
4.3
-5.2
2.2e-07
-0.07
0.05
0.90
FALSE
4
GTEx
Ovary
RP13-39P12.3
0.42
0.29
lasso
5
0.33
7.5e-09
-4.9
-5.2
2.4e-07
-0.01
0.02
0.97
FALSE