Best TWAS P=2.59e-11 · Best GWAS P=1.12e-07 conditioned to 0.0859
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ZCCHC24 | 0.12 | 0.01 | lasso | 6 | 0.03 | 0.0034 | 4.8 | 6.7 | 2.6e-11 | 0.43 | 0.04 | 0.80 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | ZCCHC24 | 0.19 | 0.01 | lasso | 5 | 0.02 | 0.0350 | 4.7 | 5.2 | 1.9e-07 | 0.18 | 0.05 | 0.64 | TRUE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ZCCHC24 | 0.06 | 0.00 | blup | 89 | 0.01 | 0.0621 | 3.4 | 5.6 | 1.9e-08 | 0.17 | 0.01 | 0.14 | FALSE |