TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced vital capacity (FVC), Best measure
:
←
→
chr11:116,467,589-117,216,213
Best TWAS P=2.55e-07 · Best GWAS P=2.91e-08 conditioned to 0.0384
116.5M
116.6M
116.7M
116.8M
116.9M
117M
117.1M
117.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
SIK3
0.04
0.04
enet
8
0.03
0.00052
-5.5
-5.2
2.5e-07
0.94
0.01
0.98
TRUE
2
The Cancer Genome Atlas
Thyroid Carcinoma
SIK3
0.04
0.05
lasso
3
0.04
0.00022
-5.1
5.1
3.0e-07
-0.69
0.06
0.86
FALSE