Best TWAS P=2.55e-07 · Best GWAS P=2.91e-08 conditioned to 0.0384
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SIK3 | 0.04 | 0.04 | enet | 8 | 0.03 | 0.00052 | -5.5 | -5.2 | 2.5e-07 | 0.94 | 0.01 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Thyroid Carcinoma | SIK3 | 0.04 | 0.05 | lasso | 3 | 0.04 | 0.00022 | -5.1 | 5.1 | 3.0e-07 | -0.69 | 0.06 | 0.86 | FALSE |