Best TWAS P=1.3e-07 · Best GWAS P=4.83e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | CDC16 | 0.17 | 0.13 | lasso | 6 | 0.15 | 4.6e-11 | -4.8 | -5.2 | 2.5e-07 | 0.79 | 0.01 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | CDC16 | 0.06 | 0.04 | lasso | 5 | 0.03 | 5.9e-03 | -5.0 | -5.3 | 1.3e-07 | 0.97 | 0.01 | 0.90 | TRUE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | CDC16 | 0.11 | 0.09 | blup | 49 | 0.09 | 1.8e-04 | -4.9 | -5.3 | 1.3e-07 | 0.76 | 0.02 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | CDC16 | 0.06 | 0.09 | lasso | 3 | 0.09 | 3.3e-09 | -4.9 | -5.1 | 2.7e-07 | 0.82 | 0.01 | 0.98 | FALSE |