TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Forced vital capacity (FVC), Best measure
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chr13:114,302,502-115,106,996
Best TWAS P=1.3e-07 · Best GWAS P=4.83e-07 conditioned to 1
114.3M
114.4M
114.5M
114.6M
114.7M
114.8M
114.9M
115M
115.1M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Colon Adenocarcinoma
CDC16
0.06
0.04
lasso
5
0.03
5.9e-03
-5.0
-5.3
1.3e-07
0.97
0.01
0.90
TRUE
3
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
CDC16
0.11
0.09
blup
49
0.09
1.8e-04
-4.9
-5.3
1.3e-07
0.76
0.02
0.96
FALSE
1
GTEx
Cells Transformed fibroblasts
CDC16
0.17
0.13
lasso
6
0.15
4.6e-11
-4.8
-5.2
2.5e-07
0.79
0.01
0.98
FALSE
4
The Cancer Genome Atlas
Thyroid Carcinoma
CDC16
0.06
0.09
lasso
3
0.09
3.3e-09
-4.9
-5.1
2.7e-07
0.82
0.01
0.98
FALSE