[Hub]/) : Traits : Forced vital capacity (FVC), Best measure :

chr13:49,557,805-51,390,447

Best TWAS P=6.07e-18 · Best GWAS P=6.6e-17 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex EBPL 0.34 0.16 bslmm 399 0.33 2.5e-41 0.17 -5.7 1.5e-08 -0.17 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex TRIM13 0.15 0.04 lasso 5 0.12 1.1e-14 8.21 -7.5 4.6e-14 -0.80 0.01 0.99 FALSE
3 GTEx Adipose Visceral Omentum EBPL 0.27 0.03 enet 17 0.20 1.4e-10 8.27 -5.6 2.7e-08 -0.20 0.03 0.97 FALSE
4 GTEx Artery Aorta EBPL 0.43 0.20 enet 78 0.28 8.1e-16 7.11 -6.2 6.1e-10 -0.35 0.18 0.82 FALSE
5 GTEx Artery Coronary EBPL 0.48 0.03 enet 99 0.12 9.7e-05 8.27 -5.1 2.9e-07 -0.31 0.04 0.86 FALSE
6 GTEx Brain Cerebellar Hemisphere EBPL 0.54 0.32 enet 17 0.34 1.2e-09 0.17 -5.2 2.2e-07 -0.16 0.08 0.87 FALSE
7 GTEx Brain Cerebellum EBPL 0.50 0.30 enet 23 0.36 1.8e-11 8.27 -6.8 9.1e-12 -0.24 0.02 0.97 FALSE
8 GTEx Brain Frontal Cortex BA9 EBPL 0.50 0.20 enet 18 0.34 7.0e-10 0.17 -5.2 1.7e-07 -0.18 0.16 0.66 FALSE
9 GTEx Brain Nucleus accumbens basal ganglia EBPL 0.25 0.11 enet 21 0.11 7.9e-04 7.07 -5.5 4.8e-08 -0.26 0.09 0.32 FALSE
10 GTEx Brain Putamen basal ganglia EBPL 0.31 -0.01 enet 18 0.05 2.9e-02 7.07 -6.6 5.3e-11 -0.37 0.04 0.40 FALSE
11 GTEx Breast Mammary Tissue (Male) EBPL 0.20 0.05 enet 6 0.03 7.9e-02 1.87 -5.3 1.1e-07 -0.16 0.04 0.24 FALSE
12 GTEx Esophagus Gastroesophageal Junction EBPL 0.27 0.24 enet 14 0.26 4.6e-10 7.03 -7.3 2.2e-13 -0.30 0.42 0.58 FALSE
13 GTEx Esophagus Muscularis EBPL 0.39 0.16 enet 36 0.29 9.2e-18 7.11 -6.0 1.7e-09 -0.26 0.99 0.01 FALSE
14 GTEx Heart Atrial Appendage EBPL 0.17 0.04 lasso 5 0.05 2.2e-03 8.27 -6.0 2.2e-09 -0.17 0.04 0.85 FALSE
15 GTEx Nerve Tibial EBPL 0.33 0.09 enet 25 0.27 4.6e-19 7.03 -5.8 7.3e-09 -0.24 0.55 0.45 FALSE
16 GTEx Nerve Tibial DLEU2 0.11 0.05 lasso 3 0.02 7.8e-03 8.34 8.2 1.8e-16 0.99 0.01 0.98 TRUE
17 GTEx Pancreas EBPL 0.18 0.10 enet 5 0.09 1.6e-04 8.27 -6.9 4.1e-12 -0.23 0.02 0.96 FALSE
18 GTEx Pituitary EBPL 0.44 0.32 enet 29 0.37 3.1e-10 7.11 -7.6 3.6e-14 -0.37 0.17 0.82 FALSE
19 GTEx Skin Not Sun Exposed Suprapubic EBPL 0.34 0.26 enet 12 0.30 4.0e-17 7.11 -7.4 1.8e-13 -0.26 0.36 0.64 FALSE
20 GTEx Skin Sun Exposed Lower leg EBPL 0.28 0.21 lasso 5 0.20 2.5e-16 6.95 -7.4 1.3e-13 -0.32 0.99 0.01 FALSE
21 GTEx Testis EBPL 0.33 0.17 lasso 6 0.24 8.4e-11 7.03 -8.6 6.1e-18 -0.32 0.08 0.92 TRUE
22 GTEx Thyroid EBPL 0.36 0.14 enet 33 0.30 5.1e-23 7.03 -7.0 3.4e-12 -0.31 0.09 0.91 FALSE
23 ROSMAP Brain Pre-frontal Cortex EBPL 0.43 0.28 lasso 8 0.43 7.3e-60 7.03 -5.3 1.4e-07 -0.21 0.99 0.01 FALSE
24 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma EBPL 0.27 0.16 blup 59 0.22 1.0e-12 -0.66 -6.1 8.6e-10 -0.24 0.36 0.63 FALSE
25 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DLEU2 0.03 0.01 blup 61 0.02 2.4e-03 8.26 8.0 1.4e-15 0.90 0.01 0.96 FALSE
26 The Cancer Genome Atlas Pancreatic Adenocarcinoma EBPL 0.21 0.09 enet 10 0.13 4.9e-06 8.27 -5.6 1.7e-08 -0.23 0.00 0.99 FALSE
27 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma EBPL 0.28 0.18 blup 59 0.19 4.3e-08 7.07 -6.3 3.3e-10 -0.23 0.02 0.97 FALSE
28 The Cancer Genome Atlas Prostate Adenocarcinoma EBPL 0.08 0.01 blup 59 0.04 6.4e-05 7.07 -6.9 6.4e-12 -0.27 0.01 0.87 FALSE
29 The Cancer Genome Atlas Stomach Adenocarcinoma EBPL 0.10 0.07 enet 7 0.08 2.8e-06 8.27 -5.4 6.2e-08 -0.23 0.00 0.99 FALSE