Best TWAS P=2.62e-10 · Best GWAS P=2.97e-08 conditioned to 0.704
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | RP11-690I21.1 | 0.24 | -0.01 | lasso | 8 | -0.01 | 6.8e-01 | -4.9 | 5.2 | 2.4e-07 | -0.81 | 0.05 | 0.41 | FALSE |
| 2 | GTEx | Liver | PDE6D | 0.21 | 0.10 | lasso | 4 | 0.09 | 1.8e-03 | -5.1 | -5.9 | 4.4e-09 | 0.46 | 0.02 | 0.82 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | DIS3L2 | 0.05 | 0.02 | enet | 10 | 0.02 | 3.8e-05 | -2.7 | -6.3 | 2.6e-10 | 0.40 | 0.09 | 0.10 | TRUE |