Best TWAS P=4.08e-08 · Best GWAS P=8.36e-10 conditioned to 0.00187
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | MAPK9 | 0.13 | 0.06 | lasso | 5 | 0.05 | 1.7e-04 | 3.9 | 5.5 | 4.1e-08 | -0.73 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | MAPK9 | 0.06 | 0.04 | lasso | 3 | 0.05 | 2.9e-05 | 5.2 | 5.1 | 2.8e-07 | -0.76 | 0.03 | 0.95 | FALSE |