Best TWAS P=8.9e-11 · Best GWAS P=4.68e-12 conditioned to 0.0162
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CENPW | 0.04 | 0.06 | lasso | 10 | 0.06 | 2.4e-07 | 6.4 | -6.5 | 8.9e-11 | -0.93 | 0.12 | 0.88 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | CENPW | 0.17 | 0.01 | enet | 15 | 0.06 | 1.8e-03 | 6.3 | -5.4 | 7.9e-08 | -0.67 | 0.04 | 0.36 | FALSE |
| 3 | METSIM | Adipose | CENPW | 0.02 | 0.02 | blup | 189 | 0.01 | 8.3e-03 | 6.3 | -5.7 | 9.1e-09 | -0.71 | 0.05 | 0.41 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CENPW | 0.04 | 0.05 | lasso | 5 | 0.05 | 2.6e-06 | 6.3 | -6.1 | 1.3e-09 | -0.90 | 0.02 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CENPW | 0.04 | 0.06 | blup | 35 | 0.05 | 9.2e-07 | 6.3 | -6.0 | 2.4e-09 | -0.90 | 0.03 | 0.97 | FALSE |