Best TWAS P=1.05e-10 · Best GWAS P=1.16e-17 conditioned to 1.97e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | LIN28B | 0.04 | 0.04 | lasso | 9 | 0.03 | 3.9e-05 | 6.8 | 6.5 | 1.0e-10 | 0.74 | 0.21 | 0.79 | TRUE |
2 | GTEx | Lung | HACE1 | 0.09 | 0.00 | lasso | 4 | 0.00 | 6.2e-01 | -1.1 | -5.2 | 2.2e-07 | -0.56 | 0.05 | 0.30 | FALSE |