Best TWAS P=3.82e-10 · Best GWAS P=1.07e-16 conditioned to 0.0679
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | U91328.21 | 0.09 | 0.01 | lasso | 8 | 0.01 | 3.0e-02 | 2.6 | 6.0 | 1.4e-09 | -0.50 | 0.06 | 0.82 | TRUE |
2 | GTEx | Ovary | U91328.19 | 0.37 | 0.17 | enet | 18 | 0.34 | 4.7e-09 | 3.8 | -5.7 | 1.1e-08 | 0.46 | 0.74 | 0.03 | TRUE |
3 | GTEx | Skin Sun Exposed Lower leg | TRIM38 | 0.09 | 0.00 | enet | 21 | 0.02 | 6.3e-03 | 2.8 | 6.3 | 3.8e-10 | -0.51 | 0.19 | 0.44 | TRUE |