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chr17:1,508,522-2,923,933

Best TWAS P=3.95e-08 · Best GWAS P=1.83e-07 conditioned to 0.979

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	SRR	0.27	0.48	lasso	1	0.48	3.5e-65	5.2	-5.2	1.8e-07	-1.00	0.00	1.00	FALSE
2	GTEx	Adipose Visceral Omentum	SRR	0.29	0.26	lasso	5	0.25	1.8e-13	5.2	-5.2	1.9e-07	-0.99	0.00	1.00	FALSE
3	GTEx	Artery Aorta	SRR	0.33	0.33	lasso	2	0.32	6.1e-18	5.2	-5.3	1.4e-07	-0.99	0.00	1.00	FALSE
4	GTEx	Artery Coronary	SRR	0.44	0.28	lasso	8	0.26	2.5e-09	4.9	-5.1	3.0e-07	-0.96	0.01	0.99	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	SRR	0.39	0.34	lasso	5	0.35	3.1e-12	5.2	-5.2	2.5e-07	-0.99	0.00	0.99	FALSE
6	GTEx	Cells Transformed fibroblasts	SRR	0.36	0.38	lasso	4	0.38	8.2e-30	5.2	-5.2	1.9e-07	-1.00	0.00	1.00	FALSE
7	GTEx	Colon Sigmoid	SRR	0.32	0.35	enet	8	0.32	9.2e-12	5.2	-5.2	2.1e-07	-0.97	0.00	1.00	FALSE
8	GTEx	Colon Transverse	SRR	0.28	0.21	lasso	5	0.19	1.6e-09	5.2	-5.2	1.9e-07	-1.00	0.00	0.99	FALSE
9	GTEx	Esophagus Gastroesophageal Junction	SRR	0.40	0.35	lasso	3	0.36	1.1e-13	5.2	-5.2	1.7e-07	-1.00	0.00	1.00	FALSE
10	GTEx	Esophagus Muscularis	SRR	0.30	0.39	lasso	3	0.38	3.4e-24	5.2	-5.2	1.6e-07	-1.00	0.00	1.00	FALSE
11	GTEx	Heart Left Ventricle	SRR	0.15	0.16	lasso	3	0.13	2.9e-07	5.2	-5.4	7.6e-08	-1.00	0.00	1.00	FALSE
12	GTEx	Lung	SRR	0.24	0.28	lasso	2	0.26	3.4e-20	5.2	-5.2	1.6e-07	-1.00	0.00	1.00	FALSE
13	GTEx	Muscle Skeletal	SRR	0.27	0.27	lasso	6	0.27	7.1e-27	5.2	-5.2	2.4e-07	-0.99	0.00	1.00	FALSE
14	GTEx	Skin Sun Exposed Lower leg	SRR	0.13	0.15	lasso	4	0.14	2.0e-11	5.2	-5.3	1.1e-07	-0.99	0.00	1.00	FALSE
15	GTEx	Thyroid	SRR	0.26	0.27	lasso	4	0.25	2.0e-19	5.2	-5.2	1.9e-07	-1.00	0.00	1.00	FALSE
16	GTEx	Whole Blood	SRR	0.09	0.03	enet	8	0.02	4.5e-03	5.2	-5.2	1.8e-07	-0.94	0.00	0.99	FALSE
17	YFS	Blood	SRR	0.17	0.22	lasso	7	0.23	2.5e-72	5.2	-5.1	3.0e-07	-0.99	0.00	1.00	FALSE
18	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SRR	0.11	0.09	lasso	4	0.10	6.8e-09	5.2	-5.5	4.0e-08	-0.95	0.00	1.00	TRUE
19	The Cancer Genome Atlas	Colon Adenocarcinoma	SRR	0.32	0.24	lasso	3	0.23	1.5e-13	5.2	-5.2	2.3e-07	-0.99	0.00	1.00	FALSE
20	The Cancer Genome Atlas	Glioblastoma Multiforme	SRR	0.24	0.16	lasso	1	0.13	9.0e-05	5.2	-5.2	1.8e-07	-1.00	0.00	0.96	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SRR	0.10	0.10	lasso	2	0.09	1.0e-10	5.2	-5.2	2.2e-07	-1.00	0.00	1.00	FALSE
22	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SRR	0.22	0.23	lasso	2	0.21	2.3e-12	5.2	-5.2	1.7e-07	-1.00	0.00	1.00	FALSE
23	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	SRR	0.08	0.09	enet	3	0.08	1.7e-04	5.2	-5.2	2.3e-07	-0.99	0.00	0.98	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	SRR	0.14	0.18	lasso	2	0.18	4.3e-21	5.2	-5.2	2.2e-07	-1.00	0.00	1.00	FALSE
25	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SRR	0.11	0.12	lasso	2	0.12	4.3e-13	5.2	-5.2	2.1e-07	-1.00	0.00	1.00	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	SRR	0.30	0.35	lasso	3	0.36	7.5e-39	5.2	-5.2	2.3e-07	-1.00	0.00	1.00	FALSE
27	The Cancer Genome Atlas	Soft Tissue Sarcoma	SRR	0.20	0.18	lasso	2	0.20	8.8e-12	5.2	-5.1	2.8e-07	-0.99	0.00	1.00	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	SRR	0.56	0.50	lasso	4	0.50	5.2e-55	5.2	-5.2	1.7e-07	-1.00	0.00	1.00	FALSE