131 significantly associated models · 40 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 33030461 | 34592020 | 2 | 1 | 1.4e-07 | 3.4e-08 | 1.0e+00 | 100 | PHC2 |
2 | 1 | 66019891 | 67086881 | 1 | 1 | 1.5e-07 | 8.7e-06 | 7.0e-01 | 99 | PDE4B |
3 | 2 | 44448632 | 45864710 | 1 | 1 | 4.0e-11 | 8.5e-11 | 1.0e+00 | 100 | RP11-89K21.1 |
4 | 2 | 47224927 | 48727280 | 1 | 1 | 2.9e-09 | 6.3e-07 | 7.8e-02 | 88 | MSH6 |
5 | 3 | 84317575 | 86808226 | 1 | 2 | 2.6e-14 | 1.7e-14 | 8.1e-03 | 88 | CADM2 |
6 | 4 | 57587795 | 58088682 | 1 | 1 | 2.3e-08 | 3.1e-09 | 4.4e-02 | 88 | C4orf14 |
7 | 5 | 86867897 | 88427942 | 1 | 1 | 1.9e-07 | 1.1e-06 | 5.0e-01 | 98 | TMEM161B-AS1 |
8 | 6 | 110588546 | 112501537 | 3 | 1 | 5.1e-12 | 1.6e-13 | 3.7e-03 | 84 | REV3L |
9 | 7 | 2646223 | 5003373 | 1 | 1 | 1.3e-07 | 3.2e-09 | 6.7e-03 | 79 | SDK1 |
10 | 7 | 98244565 | 99751521 | 3 | 1 | 2.2e-09 | 3.6e-08 | 8.1e-01 | 100 | CPSF4 |
11 | 7 | 116660803 | 118207833 | 1 | 1 | 5.3e-11 | 5.4e-12 | 5.2e-04 | 75 | CTTNBP2 |
12 | 9 | 127218258 | 128824378 | 2 | 1 | 4.3e-08 | 4.9e-08 | 2.8e-03 | 70 | PRPS1P2 |
13 | 10 | 103527782 | 105897979 | 12 | 8 | 3.5e-12 | 1.4e-10 | NaN | NaN | ARL3 AS3MT C10orf32 NT5C2 WBP1L |
14 | 11 | 58247718 | 59659006 | 1 | 1 | 8.8e-09 | 3.6e-09 | 1.0e-01 | 92 | DTX4 |
15 | 11 | 112135760 | 113846006 | 1 | 1 | 4.0e-10 | 8.0e-36 | 1.3e-27 | 24 | NCAM1 |
16 | 13 | 100942854 | 101489459 | 1 | 1 | 7.9e-08 | 1.9e-08 | 6.6e-02 | 89 | A2LD1 |
17 | 14 | 88594808 | 90043684 | 1 | 1 | 1.3e-07 | 8.7e-06 | 9.2e-01 | 100 | TTC8 |
18 | 16 | 86671 | 1417408 | 2 | 1 | 2.0e-07 | 1.6e-07 | 1.5e-01 | 92 | WDR90 |
19 | 17 | 1508522 | 2923933 | 1 | 1 | 4.0e-08 | 1.8e-07 | 9.8e-01 | 100 | SRR |
20 | 17 | 7431014 | 8850460 | 2 | 1 | 7.4e-08 | 8.4e-08 | 2.1e-01 | 94 | C17orf68 |
21 | 22 | 46185873 | 46688208 | 1 | 1 | 2.9e-07 | 3.0e-07 | 1.4e-01 | 92 | LOC100271722 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Brain Hypothalamus | 2 | 0.339 | 2.0 |
GTEx | Liver | 1 | 0.139 | 2.0 |
GTEx | Ovary | 0 | 0.000 | 2.0 |
GTEx | Adipose Subcutaneous | 2 | 0.057 | 1.9 |
GTEx | Adipose Visceral Omentum | 3 | 0.147 | 1.9 |
GTEx | Artery Coronary | 1 | 0.085 | 1.9 |
GTEx | Brain Caudate basal ganglia | 0 | 0.000 | 1.9 |
GTEx | Brain Cerebellar Hemisphere | 1 | 0.067 | 1.9 |
GTEx | Brain Cerebellum | 4 | 0.202 | 1.9 |
GTEx | Brain Cortex | 1 | 0.097 | 1.9 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.9 |
GTEx | Breast Mammary Tissue | 0 | 0.000 | 1.9 |
GTEx | Lung | 3 | 0.104 | 1.9 |
GTEx | Pancreas | 1 | 0.061 | 1.9 |
GTEx | Skin Not Sun Exposed Suprapubic | 0 | 0.000 | 1.9 |
GTEx | Skin Sun Exposed Lower leg | 2 | 0.055 | 1.9 |
GTEx | Thyroid | 3 | 0.075 | 1.9 |
GTEx | Uterus | 1 | 0.176 | 1.9 |
GTEx | Adrenal Gland | 1 | 0.069 | 1.8 |
GTEx | Artery Aorta | 2 | 0.067 | 1.8 |
GTEx | Artery Tibial | 5 | 0.133 | 1.8 |
GTEx | Brain Frontal Cortex BA9 | 0 | 0.000 | 1.8 |
GTEx | Brain Nucleus accumbens basal ganglia | 1 | 0.116 | 1.8 |
GTEx | Breast Mammary Tissue (Female) | 0 | 0.000 | 1.8 |
GTEx | Cells EBV-transformed lymphocytes | 2 | 0.141 | 1.8 |
GTEx | Cells Transformed fibroblasts | 4 | 0.095 | 1.8 |
GTEx | Colon Sigmoid | 1 | 0.068 | 1.8 |
GTEx | Colon Transverse | 2 | 0.097 | 1.8 |
GTEx | Esophagus Gastroesophageal Junction | 2 | 0.138 | 1.8 |
GTEx | Esophagus Mucosa | 1 | 0.030 | 1.8 |
GTEx | Esophagus Muscularis | 3 | 0.093 | 1.8 |
GTEx | Heart Atrial Appendage | 0 | 0.000 | 1.8 |
GTEx | Heart Left Ventricle | 1 | 0.065 | 1.8 |
GTEx | Muscle Skeletal | 3 | 0.104 | 1.8 |
GTEx | Nerve Tibial | 1 | 0.023 | 1.8 |
GTEx | Pituitary | 1 | 0.090 | 1.8 |
GTEx | Prostate | 0 | 0.000 | 1.8 |
GTEx | Small Intestine Terminal Ileum | 0 | 0.000 | 1.8 |
GTEx | Spleen | 1 | 0.071 | 1.8 |
GTEx | Stomach | 0 | 0.000 | 1.8 |
GTEx | Testis | 0 | 0.000 | 1.8 |
GTEx | Vagina | 0 | 0.000 | 1.8 |
GTEx | Whole Blood | 1 | 0.050 | 1.8 |
ROSMAP | Brain Pre-frontal Cortex | 5 | 0.114 | 1.8 |
GTEx | Brain Putamen basal ganglia | 0 | 0.000 | 1.7 |
GTEx | Breast Mammary Tissue (Male) | 0 | 0.000 | 1.7 |
METSIM | Adipose | 7 | 0.152 | 1.7 |
YFS | Blood | 2 | 0.043 | 1.7 |
CommonMind | Brain Pre-frontal Cortex | 6 | 0.112 | 1.7 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 2 | 0.045 | 1.7 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 1 | 0.091 | 1.7 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 1 | 0.048 | 1.7 |
The Cancer Genome Atlas | Esophageal Carcinoma | 1 | 0.146 | 1.7 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 3 | 0.294 | 1.7 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 4 | 0.098 | 1.7 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 1 | 0.049 | 1.7 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 4 | 0.093 | 1.7 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 2 | 0.181 | 1.7 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 3 | 0.102 | 1.7 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 3 | 0.120 | 1.7 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 1 | 0.063 | 1.7 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 2 | 0.120 | 1.7 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 3 | 0.226 | 1.7 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 1 | 0.094 | 1.7 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 1 | 0.059 | 1.7 |
The Cancer Genome Atlas | Thyroid Carcinoma | 7 | 0.136 | 1.7 |
NTR | Blood | 3 | 0.125 | 1.6 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 2 | 0.121 | 1.6 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 4 | 0.147 | 1.6 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 4 | 0.087 | 1.6 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 1 | 0.145 | 1.6 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.000 | 1.5 |