Best TWAS P=2.91e-09 · Best GWAS P=6.26e-07 conditioned to 0.0784
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | MSH6 | 0.09 | 0.04 | lasso | 2 | 0.03 | 4.1e-03 | -4.7 | -5.2 | 2.2e-07 | 0.41 | 0.01 | 0.97 | FALSE |
| 2 | GTEx | Thyroid | MSH6 | 0.15 | 0.17 | enet | 12 | 0.16 | 3.5e-12 | -4.7 | -5.9 | 2.9e-09 | 0.60 | 0.01 | 0.98 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | MSH6 | 0.11 | 0.06 | enet | 6 | 0.12 | 5.3e-12 | -4.7 | -5.2 | 2.2e-07 | 0.50 | 0.00 | 0.99 | FALSE |