[Hub]/) : Traits : Risk taking :

chr3:84,317,575-86,808,226

Best TWAS P=2.41e-18 · Best GWAS P=1.9e-18 conditioned to 0.0681

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 METSIM Adipose CADM2 0.05 0.06 lasso 10 0.06 1.3e-09 7.0 7.2 5.8e-13 0.66 0.96 0.04 FALSE
2 The Cancer Genome Atlas Brain Lower Grade Glioma CADM2 0.06 0.00 blup 339 0.00 2.7e-01 -3.6 -6.0 1.5e-09 -0.48 0.06 0.09 FALSE
3 The Cancer Genome Atlas Lung Adenocarcinoma CADM2 0.08 0.04 lasso 4 0.05 2.1e-06 8.3 8.6 5.9e-18 0.90 0.07 0.93 FALSE
4 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CADM2 0.05 0.03 lasso 3 0.04 5.0e-05 8.2 8.7 2.4e-18 0.92 0.09 0.91 TRUE
5 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CADM2 0.14 0.05 blup 339 0.09 2.7e-04 8.7 6.9 4.6e-12 0.85 0.03 0.88 FALSE
6 The Cancer Genome Atlas Thyroid Carcinoma CADM2 0.05 0.00 blup 339 0.02 3.2e-03 3.2 6.9 4.4e-12 0.68 0.04 0.52 FALSE