[Hub]/) : Traits : Risk taking :

chr2:26,505,858-28,038,799

Best TWAS P=2.71e-08 · Best GWAS P=2.71e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous KHK 0.18 0.23 lasso 7 0.26 2.4e-21 -5.3 -5.2 2.0e-07 0.98 0.02 0.98 FALSE
2 GTEx Artery Aorta KHK 0.08 0.06 enet 8 0.06 5.4e-04 -5.3 -5.3 1.4e-07 0.96 0.02 0.97 FALSE
3 GTEx Artery Tibial KHK 0.07 0.10 lasso 4 0.09 1.7e-07 -5.4 -5.2 1.7e-07 0.96 0.03 0.97 FALSE
4 GTEx Breast Mammary Tissue KHK 0.22 0.20 lasso 8 0.24 8.4e-13 -5.4 -5.2 2.4e-07 0.97 0.01 0.99 FALSE
5 GTEx Breast Mammary Tissue (Female) KHK 0.17 0.17 lasso 4 0.16 1.5e-05 -5.4 -5.2 2.0e-07 0.96 0.04 0.95 FALSE
6 GTEx Cells Transformed fibroblasts MAPRE3 0.07 0.05 lasso 5 0.05 1.7e-04 -5.2 -5.2 2.2e-07 0.96 0.04 0.96 FALSE
7 GTEx Cells Transformed fibroblasts CGREF1 0.10 0.11 lasso 8 0.12 6.4e-09 -5.0 -5.3 1.4e-07 0.97 0.04 0.96 FALSE
8 GTEx Esophagus Muscularis KHK 0.10 0.08 lasso 3 0.08 1.8e-05 -5.2 -5.3 1.4e-07 0.98 0.02 0.98 FALSE
9 GTEx Lung KHK 0.09 0.11 lasso 4 0.12 3.0e-09 -5.4 -5.3 1.2e-07 0.98 0.01 0.99 FALSE
10 GTEx Muscle Skeletal KHK 0.16 0.19 lasso 4 0.24 5.0e-23 -5.0 -5.3 1.5e-07 0.98 0.01 0.99 FALSE
11 GTEx Nerve Tibial KHK 0.24 0.19 lasso 7 0.20 2.2e-14 -5.4 -5.4 8.5e-08 0.94 0.01 0.99 FALSE
12 GTEx Ovary KHK 0.29 -0.01 lasso 3 0.01 1.6e-01 -5.3 -5.3 1.1e-07 0.96 0.03 0.55 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic KHK 0.19 0.28 lasso 5 0.26 2.9e-14 -5.4 -5.4 7.7e-08 0.98 0.01 0.99 FALSE
14 GTEx Skin Sun Exposed Lower leg CGREF1 0.07 0.00 lasso 7 0.01 7.1e-02 -5.3 -5.2 2.0e-07 0.82 0.03 0.85 FALSE
15 GTEx Skin Sun Exposed Lower leg KHK 0.21 0.30 lasso 6 0.34 3.2e-29 -5.4 -5.2 1.6e-07 0.98 0.01 0.99 FALSE
16 GTEx Testis KHK 0.20 0.15 lasso 4 0.17 8.0e-08 -5.2 -5.4 7.8e-08 0.97 0.02 0.98 FALSE
17 GTEx Thyroid KHK 0.15 0.19 lasso 4 0.22 1.1e-16 -5.3 -5.3 9.0e-08 0.97 0.01 0.99 FALSE
18 YFS Blood KHK 0.06 0.07 lasso 5 0.06 2.2e-20 -5.4 -5.4 6.8e-08 0.98 0.02 0.98 FALSE
19 The Cancer Genome Atlas Breast Invasive Carcinoma KHK 0.04 0.07 lasso 2 0.07 1.2e-13 -5.6 -5.5 3.1e-08 1.00 0.01 0.99 FALSE
20 The Cancer Genome Atlas Glioblastoma Multiforme MAPRE3 0.18 0.05 blup 53 0.09 1.4e-03 -5.3 -5.4 6.5e-08 0.94 0.02 0.81 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CGREF1 0.05 0.03 blup 37 0.03 4.3e-04 -5.2 -5.4 8.4e-08 0.91 0.02 0.96 FALSE
22 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CGREF1 0.03 0.02 blup 37 0.03 2.3e-04 -4.8 -5.4 7.5e-08 0.92 0.02 0.93 FALSE
23 The Cancer Genome Atlas Lung Squamous Cell Carcinoma KHK 0.02 0.02 blup 36 0.02 2.2e-03 -5.3 -5.3 1.3e-07 0.97 0.01 0.93 FALSE
24 The Cancer Genome Atlas Pancreatic Adenocarcinoma KHK 0.13 0.14 lasso 2 0.13 5.1e-06 -5.6 -5.6 2.7e-08 1.00 0.01 0.98 TRUE
25 The Cancer Genome Atlas Prostate Adenocarcinoma KHK 0.13 0.21 blup 37 0.23 1.4e-23 -5.3 -5.4 5.5e-08 0.96 0.02 0.98 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma OST4 0.02 0.02 lasso 1 0.02 8.9e-03 -5.3 5.3 1.0e-07 -0.93 0.01 0.74 FALSE
27 The Cancer Genome Atlas Thyroid Carcinoma KHK 0.09 0.19 lasso 5 0.19 2.2e-18 -5.3 -5.3 1.5e-07 0.98 0.02 0.98 FALSE