Best TWAS P=7.09e-09 · Best GWAS P=2.4e-09 conditioned to 0.0915
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | MNT | 0.14 | 0.05 | lasso | 5 | 0.04 | 3.8e-04 | -4.7 | -5.2 | 2.2e-07 | 0.23 | 0.41 | 0.47 | FALSE |
| 2 | GTEx | Lung | RP1-59D14.1 | 0.08 | 0.03 | lasso | 2 | 0.01 | 8.6e-02 | -4.7 | -5.3 | 1.2e-07 | 0.18 | 0.11 | 0.13 | TRUE |
| 3 | YFS | Blood | PAFAH1B1 | 0.13 | 0.10 | enet | 31 | 0.09 | 6.1e-29 | -6.0 | -5.8 | 7.1e-09 | 0.94 | 0.00 | 1.00 | TRUE |