[Hub]/) : Traits : Body mass index (BMI) :

chr10:133,309,117-135,192,153

Best TWAS P=1.15e-11 · Best GWAS P=1.28e-11 conditioned to 0.18

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DPYSL4 0.09 0.03 enet 16 0.05 9.9e-07 6.8 5.1 3.1e-07 0.81 0.01 0.99 FALSE
2 GTEx Adrenal Gland DPYSL4 0.38 0.21 lasso 5 0.39 3.4e-15 3.0 5.6 2.2e-08 0.74 0.05 0.95 FALSE
3 GTEx Muscle Skeletal DPYSL4 0.27 0.06 enet 9 0.10 2.0e-10 2.9 5.1 2.9e-07 0.68 0.86 0.14 FALSE
4 GTEx Pituitary DPYSL4 0.24 0.11 lasso 4 0.26 3.0e-07 3.1 5.9 4.1e-09 0.63 0.02 0.81 FALSE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma DPYSL4 0.28 0.22 enet 19 0.25 3.0e-21 -5.6 5.1 2.7e-07 0.85 0.02 0.98 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma DPYSL4 0.19 0.30 enet 19 0.37 3.1e-79 6.8 5.7 1.6e-08 0.90 0.00 1.00 FALSE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DPYSL4 0.31 0.19 lasso 10 0.18 3.4e-09 6.8 6.8 1.2e-11 0.91 0.00 1.00 TRUE
8 The Cancer Genome Atlas Glioblastoma Multiforme STK32C 0.13 -0.01 blup 107 0.08 1.6e-03 2.6 -5.5 3.5e-08 -0.36 0.04 0.07 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DPYSL4 0.16 0.24 blup 60 0.27 7.6e-31 -5.8 5.3 1.1e-07 0.92 0.01 0.99 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DPYSL4 0.16 0.21 enet 16 0.24 7.1e-27 6.8 5.8 6.3e-09 0.91 0.00 1.00 FALSE
11 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DPYSL4 0.17 0.24 lasso 3 0.23 2.4e-13 6.8 6.7 3.0e-11 0.99 0.00 1.00 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma DPYSL4 0.13 0.12 lasso 7 0.16 3.1e-17 6.8 5.9 4.3e-09 0.95 0.00 1.00 FALSE
13 The Cancer Genome Atlas Liver Hepatocellular Carcinoma DPYSL4 0.13 0.11 enet 7 0.08 2.0e-04 6.8 6.7 2.2e-11 0.95 0.01 0.99 FALSE
14 The Cancer Genome Atlas Lung Adenocarcinoma DPYSL4 0.17 0.16 enet 18 0.23 1.5e-26 6.7 5.9 3.4e-09 0.87 0.00 1.00 FALSE
15 The Cancer Genome Atlas Lung Adenocarcinoma GPR123 0.05 0.00 blup 56 0.02 8.0e-04 4.1 6.1 9.9e-10 0.00 0.00 0.27 TRUE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DPYSL4 0.11 0.07 blup 60 0.13 1.0e-14 6.8 5.2 2.3e-07 0.83 0.00 1.00 FALSE
17 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma DPYSL4 0.24 0.21 lasso 7 0.28 2.5e-19 6.8 5.8 6.6e-09 0.84 0.00 1.00 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma DPYSL4 0.34 0.37 enet 15 0.46 2.2e-53 -5.9 5.7 1.0e-08 0.93 0.00 1.00 FALSE
19 The Cancer Genome Atlas Skin Cutaneous Melanoma DPYSL4 0.27 0.07 blup 64 0.07 7.1e-03 6.8 5.4 8.4e-08 0.88 0.01 0.78 FALSE
20 The Cancer Genome Atlas Testicular Germ Cell Tumors DPYSL4 0.17 0.12 blup 64 0.11 1.3e-04 -5.8 6.1 1.4e-09 0.85 0.01 0.97 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma DPYSL4 0.30 0.24 enet 15 0.38 1.7e-38 3.0 5.8 5.0e-09 0.78 0.01 0.99 FALSE