TWAS hub - GPR123

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.3250	0.0470	5.3e-14	0.142	0.145	0.193	0.144	0.180	7.1e-17	3.2e-17	5.5e-23	3.7e-17	2.2e-21
2	TCGA	Lung Adenocarcinoma	0.0466	0.0196	2.1e-03	0.001	0.024	0.012	NA	0.008	2.3e-01	8.0e-04	1.3e-02	NA	3.6e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Chest pain or discomfort	5.8	8.4	10.8	2.5	3.3
Commuting to job workplace: Car/motor vehicle	5.8	6.6	12.1	-1.1	-3.5
Arm fat percentage (left)	5.6	22.4	40.2	2.2	6.3
Arm fat percentage (right)	5.4	21.3	36.7	2.4	6.1
Wheeze or whistling in the chest in last year	5.3	9.4	12.9	2.4	3.6
Medication: Paracetamol	5.2	8.6	9.6	3.1	2.8
Body fat percentage	5.2	20.7	36.2	2.3	6.0
Body mass index (BMI)	5.0	21.2	37.3	2.2	6.1
Whole body fat mass	4.9	20.6	38.0	1.8	6.2
Leg fat mass (left)	4.9	19.3	36.0	1.6	6.0
Leg fat mass (right)	4.8	18.6	34.4	1.7	5.9
Arm fat mass (left)	4.8	19.8	36.2	1.8	6.0
Leg fat percentage (left)	4.8	17.3	30.5	2.0	5.5
Arm fat mass (right)	4.7	19.5	35.2	1.9	5.9
Seen doctor (GP) for nerves, anxiety, tension or depression	4.7	7.2	13.5	0.9	3.7
Miserableness	4.7	8.2	10.6	3.3	2.4
Relative age voice broke	4.6	7.1	11.1	-3.3	-1.7
Leg fat percentage (right)	4.6	16.7	28.8	2.1	5.4
Trunk fat percentage	4.5	17.9	30.7	2.3	5.5
Trunk fat mass	4.4	19.0	34.6	1.9	5.9
Shortness of breath walking on level ground	3.9	4.6	6.8	1.6	2.6
Stomach or abdominal pain in last month	3.8	4.7	6.2	2.5	1.8
Smoking status: Previous	3.8	5.7	8.4	2.9	1.7
Age at First Birth	3.7	5.4	5.9	-2.4	-2.2
Medication for pain relief, constipation, heartburn	3.7	6.3	7.8	-2.2	-2.8
Waist circumference	3.6	13.3	26.3	0.5	5.1
Number of treatments/medications taken	3.5	6.4	11.2	1.2	3.3
Relative age of first facial hair	3.4	7.0	10.7	-3.3	-1.8
Hip circumference	3.4	14.7	28.9	0.7	5.4
Fed-up feelings	3.3	5.9	8.1	2.8	1.9
Medication: Paracetamol	3.3	5.1	5.8	2.4	2.1
Past tobacco smoking	3.2	5.9	6.4	-2.5	-2.3
Age at last live birth	3.2	4.6	7.0	-2.6	-1.5
Medication: Ramipril	3.0	3.8	5.8	-1.3	2.4
Weight	3.0	14.8	28.8	0.9	5.4
Overall health rating	3.0	6.5	9.9	3.1	1.8
Knee pain experienced in last month	3.0	4.6	4.9	2.1	2.2
Fasting Glucose	2.9	3.5	6.3	0.8	2.5
Time employed in main current job	2.9	3.3	5.0	2.2	-1.3
Commuting to job workplace: Walk	2.9	3.1	6.0	-0.5	2.5
Mean Putamen Volume	2.8	3.3	5.5	1.0	2.3
Qualifications: College or University degree	2.8	8.9	17.2	-4.1	-0.8
Number of self-reported non-cancer illnesses	2.8	4.9	5.8	2.0	2.4
Commuting to job workplace: Public transport	2.8	3.4	6.2	-0.7	2.5
Loneliness, isolation	2.7	3.8	5.9	2.4	1.3
Pain experienced in last month	2.7	4.5	5.9	-1.7	-2.4
Number of full sisters	2.6	3.1	3.5	1.9	1.7
Depressed Affect (Nagel 2018)	2.5	5.4	6.7	2.6	2.0
Qualifications: A levels/AS levels or equivalent	2.4	5.3	10.5	-3.2	-0.2
Worry too long after embarrassment	2.4	4.1	4.8	2.2	1.8
Mother’s age at death	2.4	3.1	3.1	-1.7	-1.8
BMI	2.3	13.5	20.9	2.5	4.6
Townsend deprivation index at recruitment	2.3	3.3	6.5	-0.3	2.5
Taking other prescription medications	2.2	3.4	4.5	2.1	1.5
Qualifications: None of the above	2.2	4.8	7.8	2.8	1.3
Depression (self-reported)	2.2	2.7	4.3	1.0	2.1
Exposure to tobacco smoke outside home	2.2	3.0	4.2	-1.3	2.1
Osteoarthritis (self-reported)	2.2	2.9	4.3	2.1	1.2
Handedness (chirality/laterality): Left-handed	2.1	2.5	2.6	1.6	1.6
Guilty feelings	2.1	3.2	4.3	1.5	2.1
Noisy workplace	2.0	2.5	4.8	-0.4	2.2
Mouth/teeth dental problems: Bleeding gums	2.0	2.5	5.0	0.2	2.2
Leg pain on walking	2.0	2.6	5.1	-0.1	2.3
Long-standing illness, disability or infirmity	2.0	3.1	3.7	1.9	1.6
Average weekly beer plus cider intake	2.0	2.9	5.8	2.4	-0.3
Length of working week for main job	1.9	2.1	4.1	2.0	-0.1
Emphysema/chronic bronchitis	1.9	2.1	2.1	1.5	1.4
Alcohol usually taken with meals	1.8	3.0	5.8	-2.4	-0.4
Ever highly irritable/argumentative for 2 days	1.8	2.2	2.8	1.2	1.7
Neck or shoulder pain in last month	1.8	2.5	3.2	1.8	1.3
Qualifications: nursing, teaching	1.8	2.7	4.3	-2.1	-1.1
Medication: Lisinopril	1.8	2.3	4.3	2.1	-0.5
Ever had prostate specific antigen (PSA) test	1.8	2.0	3.8	-1.9	0.5
Hair/balding pattern: Pattern 2	1.7	2.2	3.2	1.1	1.8
Number of live births	1.7	2.5	4.5	2.1	0.7
Prospective memory result	1.7	2.0	3.5	-1.9	0.8
Blood clot in the leg (DVT)	1.7	2.2	4.0	-2.0	0.7
Family relationship satisfaction	1.7	2.0	4.0	2.0	-0.2
Heart attack/myocardial infarction (self-reported)	1.7	2.2	3.7	1.9	-0.9
Heart attack	1.6	2.1	3.5	1.9	-0.8
Medication: Lansoprazole	1.6	1.8	3.3	-0.6	1.8
Tense / ‘highly strung’	1.6	2.6	4.4	2.1	0.9
Forced vital capacity (FVC), Best measure	1.6	5.9	9.8	-3.1	-1.4
Ulcerative Colitis (UC)	1.5	2.8	3.0	-1.7	-1.6
Neuroticism	1.5	3.7	6.5	0.9	2.5
Hearing difficulty/problems with background noise	1.5	2.4	4.1	0.9	2.0
Had other major operations	1.5	1.8	2.7	1.6	-0.9
Financial difficulties in last 2 years	1.5	2.0	2.1	-1.4	1.4
Pulse wave peak to peak time	1.5	1.7	2.7	0.8	-1.6
Medication: Omeprazole	1.5	1.8	3.6	1.9	-0.1
Had menopause	1.4	1.8	3.1	0.7	-1.8
Mouth/teeth dental problems	1.4	2.2	3.0	-1.1	-1.7
Pulse wave Arterial Stiffness index	1.4	1.6	2.7	-0.8	1.6
Back pain experienced in last month	1.4	2.1	3.8	2.0	0.6
Pain type(s) experienced in last month: Hip pain	1.4	1.8	2.9	0.8	1.7
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	3.1	1.8	0.5
Schizophrenia vs Biploar Disorder	1.3	1.7	3.3	1.8	0.0
Schizophrenia (2014)	1.3	2.9	5.9	2.4	0.0
Leg fat-free mass (left)	1.3	6.8	13.6	-0.0	3.7
High blood pressure	1.3	3.6	6.5	-0.8	2.5
Age at first live birth	1.3	2.4	3.2	-1.8	-1.3
Ever had bowel cancer screening	1.3	1.5	2.3	-0.8	-1.5
Eye problems/disorders: Cataract	1.3	1.5	2.1	1.4	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.8	5.6	-2.4	0.1
Ever smoked	1.3	2.3	2.6	1.6	1.4
Basal cell carcinoma (self-reported)	1.3	1.5	2.5	-0.7	1.6
Crohns Disease (2017)	1.2	2.6	3.5	1.3	1.9
Ovarian Cancer	1.2	1.6	3.1	-1.8	0.2
Ever used hormone-replacement therapy (HRT)	1.2	1.5	2.7	1.6	0.6
Supplements: Glucosamine	1.2	1.6	2.4	-1.6	0.8
Leg predicted mass (left)	1.2	6.4	12.8	0.1	3.6
Forced vital capacity (FVC)	1.2	4.8	9.5	-3.1	-0.4
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.6	3.1	-0.2	1.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.9	7.7	-2.8	-0.3
Exposure to tobacco smoke at home	1.2	1.3	2.6	0.1	1.6
Illnesses of father: None of the above (group 1)	1.2	1.4	2.0	0.9	-1.4
Basal metabolic rate	1.2	6.7	13.3	-0.3	3.6
Diastolic blood pressure, automated reading	1.2	3.7	7.3	0.2	2.7
Cholesterol lowering medication	1.2	1.8	3.0	1.7	0.8
Supplements: Calcium	1.2	1.3	2.1	0.7	-1.5
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	3.0	-1.7	0.4
Neuroticism (Nagel 2018)	1.1	2.7	3.8	1.2	1.9
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.1	0.4	-1.5
High blood pressure (mother)	1.1	1.5	2.4	1.6	-0.8
Happiness	1.1	1.4	2.7	1.7	-0.2
Headache pain in last month	1.1	1.8	3.5	-0.3	1.9
Health satisfaction	1.1	1.5	2.9	0.1	1.7
Medication: Ibuprofen	1.1	1.3	2.6	0.1	1.6
Leg fat-free mass (right)	1.1	6.1	12.2	-0.1	3.5
Leg predicted mass (right)	1.1	5.9	11.8	-0.1	3.4
Alcohol drinker status: Previous	1.1	1.3	1.4	-1.1	1.2
Ulcerative Colitis	1.0	1.4	2.8	-1.7	0.0
Systolic blood pressure, automated reading	1.0	3.0	4.7	2.2	1.2
Medication: Co-codamol	1.0	1.1	1.5	1.2	0.9
Medication: Metformin	1.0	1.4	2.9	-0.1	1.7
Chronic bronchitis/emphysema (father)	1.0	1.2	1.2	1.1	1.1
Neuroticism score	1.0	2.2	3.4	1.0	1.8
Impedance of arm (right)	1.0	4.6	9.0	-0.4	-3.0
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	6.9	-2.6	0.4
Mouth/teeth dental problems: Dentures	1.0	1.7	2.2	1.5	1.1
Arm fat-free mass (right)	1.0	4.9	9.7	-0.4	3.1
Number of full brothers	1.0	1.2	2.4	0.2	1.5
Eye problems/disorders: None of the above	1.0	1.2	1.9	-1.4	-0.7
Illnesses of father: Heart disease	1.0	1.4	2.8	-1.7	0.2
Illnesses of siblings: Diabetes	1.0	1.3	2.0	-0.7	1.4
Vascular/heart problems diagnosed by doctor	1.0	2.7	4.7	0.8	-2.2
Alzheimer’s Disease (in mother)	0.9	1.1	1.3	0.9	1.1
Smoking Status	0.9	2.1	3.7	0.7	1.9
Hand grip strength (left)	0.9	2.4	3.0	-1.4	-1.7
Medication: Levothyroxine sodium	0.9	1.5	2.5	1.6	-0.8
Number of incorrect matches in round	0.9	1.5	1.8	-1.3	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	1.3	-1.1	-0.9
Birth weight of first child	0.9	1.7	3.3	-1.8	0.3
Birth weight	0.9	2.0	2.6	1.6	1.2
Arm predicted mass (right)	0.9	4.8	9.4	-0.3	3.1
Hypertension (Self-reported)	0.9	2.6	4.4	-0.9	2.1
Average weekly red wine intake	0.9	1.3	2.2	-0.6	-1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	2.0	1.4	0.4
Financial situation satisfaction	0.9	1.2	2.1	-0.5	1.5
Age started oral contraceptive pill	0.9	1.1	2.1	1.4	-0.3
Worry (Nagel 2018)	0.8	1.8	2.9	-1.7	0.8
Neuroticism (2016)	0.8	1.1	2.2	-0.0	1.5
Diabetes (mother)	0.8	1.0	1.5	-1.2	0.7
Impedance of leg (right)	0.8	4.0	7.7	-0.5	-2.8
Maternal smoking around birth	0.8	1.1	2.1	1.4	0.4
Impedance of leg (left)	0.8	3.8	7.2	-0.6	-2.7
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	1.4	0.7	1.2
Impedance of arm (left)	0.8	3.6	6.4	-0.9	-2.5
Number of children fathered	0.8	0.9	1.6	-1.3	-0.4
Suffer from ‘nerves’	0.8	1.3	2.4	-1.6	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	1.6	0.6	1.3
Mood swings	0.8	1.5	1.8	1.3	1.1
Whole body water mass	0.8	4.4	8.6	-0.6	2.9
Hearing aid user	0.8	0.9	1.5	-1.2	-0.5
Arm fat-free mass (left)	0.8	4.1	8.2	0.2	2.9
Impedance of whole body	0.8	4.1	8.0	-0.4	-2.8
Arm predicted mass (left)	0.8	4.0	8.1	-0.0	2.8
Lupus	0.7	1.0	1.1	-1.0	-1.0
Respiratory disease	0.7	1.5	1.8	1.4	1.1
Sensitivity / hurt feelings	0.7	1.1	1.8	1.4	0.7
Hand grip strength (right)	0.7	1.9	2.6	-1.6	-1.1
Average weekly fortified wine intake	0.7	0.8	1.4	1.2	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	3.1	1.8	0.3
Allergy	0.7	1.5	2.3	-0.8	-1.5
Diabetes (self-reported)	0.7	1.1	1.8	0.6	1.3
Pulse rate	0.7	1.2	1.9	-0.7	1.4
Lung cancer (father)	0.7	0.8	1.2	1.1	-0.7
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	1.9	0.9	-1.4
Medication: Blood pressure	0.7	1.3	2.1	-0.7	1.5
Medication: Seretide 50 evohaler	0.7	0.8	1.5	-0.4	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.0	-1.0	-0.8
Alcohol intake frequency.	0.7	1.7	2.5	1.0	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	1.4	0.4	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	2.8	-1.7	-0.5
Whole body fat-free mass	0.7	4.2	8.1	-0.5	2.9
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	0.9	-0.9	0.7
Medication for cholesterol	0.7	1.1	2.0	-1.4	0.4
Average weekly champagne plus white wine intake	0.7	1.0	1.5	-1.2	-0.7
Schizophrenia (2018)	0.6	1.3	2.6	1.6	0.0
Alzheimer’s Disease (in father)	0.6	0.6	0.9	-0.6	0.9
Diabetes (father)	0.6	0.8	1.6	0.1	1.2
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	0.8	-0.9	-0.8
Sitting height	0.6	4.1	8.0	-2.8	0.4
Nervous feelings	0.6	1.2	2.3	-1.5	0.1
Falls in the last year	0.6	0.8	1.4	1.2	0.4
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	1.9	-1.4	-0.2
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.5	1.2	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.5	-0.2	1.2
Wears glasses or contact lenses	0.6	0.7	1.3	-0.4	-1.2
Medication: Blood pressure	0.6	1.1	2.1	1.4	-0.3
Alzheimer’s Disease (including proxy)	0.5	0.7	1.4	-0.1	1.2
Prostate Cancer	0.5	0.8	1.0	1.0	-0.8
LDL Cholesterol	0.5	0.7	1.3	0.4	-1.1
Cardiovascular Disease	0.5	1.7	2.3	-1.1	1.5
Supplements: Zinc	0.5	0.5	0.8	-0.9	0.4
Severe depression (siblings)	0.5	0.6	1.0	0.4	1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	0.8	0.9	-0.6
Age when periods started (menarche)	0.5	1.2	2.1	-0.5	-1.5
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.9	1.0	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	1.5	1.2	1.0
Father’s age at death	0.5	0.7	1.3	0.0	-1.2
High blood pressure (siblings)	0.5	0.7	1.2	0.4	1.1
Mineral and other dietary supplements	0.5	0.6	1.0	-0.5	-1.0
Tinnitus: Yes, now most or all of the time	0.5	0.6	0.8	-0.7	-0.9
Illnesses of father: High blood pressure	0.5	0.6	1.0	-0.4	1.0
Heart disease (siblings)	0.5	0.6	1.1	1.0	0.4
Verbal and Numeric Reasoning (VNR)	0.4	1.0	1.9	-0.1	1.4
Primary Biliary Cirrhosis	0.4	0.5	1.0	1.0	0.3
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.0	-1.0	0.0
Chronotype (morning person)	0.4	0.9	1.7	-1.3	0.3
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	0.9	0.5	0.9
Medication: Atenolol	0.4	0.5	0.6	0.8	0.7
Trunk fat-free mass	0.4	2.5	4.3	-0.9	2.1
Trunk predicted mass	0.4	2.5	4.2	-0.9	2.0
Standing height	0.4	3.5	5.8	-2.4	-1.1
Peak expiratory flow (PEF)	0.4	1.0	1.5	-1.2	0.8
Loud music exposure frequency	0.4	0.5	0.9	1.0	-0.0
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.2	0.4	-1.1
Had major operations	0.4	0.4	0.8	-0.9	0.3
Medication: Aspirin	0.4	0.5	1.0	-0.1	1.0
Supplements: Vitamin C	0.4	0.5	0.8	-0.3	0.9
Breast cancer (self-reported)	0.4	0.5	0.9	-1.0	-0.1
Medication: Gliclazide	0.4	0.5	0.9	-0.9	-0.4
Ever taken oral contraceptive pill	0.4	0.4	0.6	-0.4	0.8
Risk taking	0.4	0.6	1.0	-0.4	1.0
Unable to work because of sickness or disability	0.4	0.5	0.9	1.0	-0.1
Commuting to job workplace: Cycle	0.4	0.5	0.8	-0.3	0.9
Bipolar Disorder or Schizophrenia	0.3	0.8	1.6	1.3	0.0
Intelligence (Savage-Jansen 2018)	0.3	0.9	1.5	0.5	1.2
Breast Cancer	0.3	0.8	1.5	-0.3	1.2
Body Mass Index (BMI) (2010)	0.3	0.4	0.7	0.4	0.8
Coronary Artery Disease (CAD)	0.3	0.4	0.7	-0.9	0.0
Allergy or Eczema	0.3	0.8	0.8	0.9	0.9
Lung FVC	0.3	1.4	1.7	-1.3	-1.0
Medication for hormone replacement therapy	0.3	0.3	0.3	0.6	-0.6
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.1	0.5	1.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.7	0.8	0.3
Illnesses of siblings	0.3	0.4	0.5	0.5	-0.7
Asthma	0.3	0.6	1.2	1.1	0.2
Illnesses of mother	0.3	0.4	0.7	-0.8	0.4
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.7	0.9	-0.3
Comparative body size at age 10	0.3	0.8	1.1	0.8	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.4	-0.6	0.6
Heart disease (mother)	0.3	0.4	0.5	0.5	-0.7
Pulse rate, automated reading	0.3	0.8	1.1	-1.1	0.7
Friendships satisfaction	0.3	0.3	0.5	0.7	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	0.7	0.4	0.9
Asthma (self-reported)	0.3	0.6	1.2	1.1	-0.0
Osteoporosis (self-reported)	0.3	0.4	0.7	-0.8	-0.4
High cholesterol (Self-reported)	0.3	0.5	0.6	0.7	0.8
Medication: Atorvastatin	0.3	0.3	0.5	-0.4	0.7
Pack years of smoking	0.3	0.4	0.5	0.7	0.5
Reaction Time	0.2	0.3	0.6	0.1	-0.8
Crohns Disease (2012)	0.2	0.3	0.6	0.8	0.0
HDL Cholesterol	0.2	0.4	0.7	0.2	-0.8
Blood Platelet Count	0.2	1.7	2.5	-1.6	1.0
Blood White Count	0.2	1.1	1.2	1.0	1.1
Height	0.2	3.8	6.8	-2.6	-0.9
Hypothyroidism (self reported)	0.2	0.5	0.9	0.0	-1.0
Ever had hysterectomy (womb removed)	0.2	0.2	0.3	0.5	-0.3
Vitamin and mineral supplements	0.2	0.2	0.3	-0.6	0.4
Pack years adult smoking proportion	0.2	0.3	0.3	0.5	0.5
Medication: Simvastatin	0.2	0.3	0.3	0.6	0.5
Alcohol intake versus 10 years previously	0.2	0.3	0.4	0.7	-0.2
Hair/balding pattern: Pattern 3	0.2	0.3	0.5	-0.7	-0.4
Hair/balding pattern: Pattern 4	0.2	0.5	1.0	-1.0	0.2
Pulse wave reflection index	0.2	0.3	0.3	-0.6	0.4
Glaucoma (self-reported)	0.2	0.2	0.4	0.2	0.7
Medication: Amlodipine	0.2	0.2	0.4	0.2	0.6
Migraine (self-reported)	0.2	0.2	0.3	0.5	0.3
Medication: Allopurinol	0.2	0.2	0.4	0.3	-0.7
Diabetes diagnosed by doctor	0.2	0.3	0.3	0.6	0.6
Medication: Aspirin	0.2	0.2	0.5	-0.1	0.7
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.5	0.7	0.3
Number of operations (self-reported)	0.2	0.3	0.5	0.2	0.7
Irritability	0.2	0.3	0.4	0.6	0.5
Fractured/broken bones in last 5 years	0.2	0.3	0.5	0.7	-0.0
Ever depressed for a whole week	0.2	0.2	0.3	-0.6	0.3
Myopia	0.2	0.3	0.4	-0.6	-0.6
HbA1C	0.1	0.2	0.3	0.5	0.2
Rheumatoid Arthritis	0.1	0.2	0.3	0.0	0.6
Triglycerides	0.1	0.2	0.4	0.6	0.1
Blood Red Count	0.1	0.6	0.6	0.8	0.7
Heel T-Score	0.1	0.7	1.1	1.0	-0.6
Waist Hip Ratio (WHR)	0.1	0.6	0.6	-0.8	-0.7
Systolic Blood Pressure	0.1	0.6	0.7	0.7	0.8
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.2	-0.2	0.5
Lung FEV1/FVC ratio	0.1	0.7	1.4	-0.2	1.2
Hearing difficulty/problems: Yes	0.1	0.2	0.2	-0.5	0.4
Angina	0.1	0.1	0.1	0.3	-0.3
Current tobacco smoking	0.1	0.2	0.3	0.5	-0.3
Serious illness, injury or assault to yourself	0.1	0.2	0.3	0.0	0.6
Multivitamins +/- minerals	0.1	0.2	0.3	0.2	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.2	-0.1	0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.2	0.0	-0.4
Worrier / anxious feelings	0.1	0.2	0.3	-0.5	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.3	0.6	-0.1
Medication: Cholesterol lowering	0.1	0.1	0.2	0.2	0.4
Breastfed as a baby	0.1	0.1	0.1	0.3	-0.3
Gout (self-reported)	0.1	0.1	0.2	0.4	-0.0
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	0.4	-0.2
Angina (self-reported)	0.1	0.1	0.2	0.5	-0.2
Mean time to correctly identify matches	0.1	0.2	0.3	0.6	-0.4
Comparative height size at age 10	0.1	0.7	1.3	-0.2	-1.1
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.3	0.5	-0.2
Eye problems/disorders: Glaucoma	0.1	0.1	0.3	0.0	0.5
Alcohol drinker status: Never	0.1	0.1	0.3	0.5	-0.1
Bipolar Disorder (2018)	0.0	0.0	0.0	0.1	0.0
Depression (Nagel 2018)	0.0	0.0	0.1	0.1	-0.3
Irritable Bowel Disease (IBD)	0.0	0.1	0.1	-0.3	0.3
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Blood Eosinophil Count	0.0	0.1	0.2	-0.4	0.1
Hair Pigment	0.0	0.3	0.5	-0.2	-0.7
Tanning	0.0	0.5	1.0	-0.0	-1.0
Average weekly spirits intake	0.0	0.0	0.1	0.1	-0.3
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.1	-0.3	-0.1
Qualifications: CSEs or equivalent	0.0	0.0	0.0	0.1	0.0
Pain all over the body in last month	0.0	0.0	0.1	0.1	0.3
Fluid intelligence score	0.0	0.0	0.1	-0.1	-0.2
Smoking status: Current	0.0	0.0	0.0	-0.2	-0.2
Medication: Bendroflumethiazide	0.0	0.1	0.1	0.2	0.3

Hub : Genes

GPR123

Models

Trait associations