[Hub]/) : Traits : Body mass index (BMI) : ← →

chr11:198,510-1,702,321

Best TWAS P=1.13e-08 · Best GWAS P=3.43e-08 conditioned to 0.474

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	AP2A2	0.09	0.04	enet	30	0.07	1.9e-08	3.5	-5.5	5.0e-08	0.40	0.06	0.93	FALSE
2	CommonMind	Brain Pre-frontal Cortex	POLR2L	0.09	0.09	enet	16	0.10	4.6e-12	-4.6	-5.7	1.6e-08	0.63	0.32	0.67	FALSE
3	GTEx	Adipose Subcutaneous	POLR2L	0.19	0.12	enet	18	0.11	3.4e-09	-4.6	-5.3	1.3e-07	0.59	0.37	0.61	FALSE
4	GTEx	Artery Coronary	AP006621.6	0.26	0.11	enet	20	0.12	5.3e-05	3.7	5.4	7.5e-08	-0.82	0.05	0.92	FALSE
5	GTEx	Brain Cortex	AP006621.6	0.37	0.01	lasso	3	0.11	6.9e-04	3.7	5.1	3.0e-07	-0.40	0.06	0.12	FALSE
6	GTEx	Brain Frontal Cortex BA9	AP006621.5	0.18	0.03	lasso	6	0.04	2.6e-02	-4.9	5.7	1.1e-08	-0.92	0.05	0.60	TRUE
7	GTEx	Brain Hippocampus	AP006621.5	0.26	0.22	enet	20	0.15	2.1e-04	3.8	5.4	7.1e-08	-0.60	0.09	0.42	FALSE
8	GTEx	Brain Hypothalamus	PNPLA2	0.23	-0.01	lasso	9	0.00	4.0e-01	-4.9	-5.2	2.0e-07	0.93	0.04	0.35	FALSE
9	GTEx	Muscle Skeletal	AP006621.6	0.15	0.12	enet	10	0.14	1.6e-13	3.8	5.4	7.7e-08	-0.80	0.65	0.32	FALSE
10	GTEx	Pancreas	EFCAB4A	0.23	0.19	enet	8	0.16	4.1e-07	-5.5	5.4	5.6e-08	-0.97	0.01	0.99	FALSE
11	GTEx	Testis	POLR2L	0.16	0.03	enet	10	0.03	1.9e-02	-5.1	-5.4	6.8e-08	0.75	0.06	0.88	FALSE
12	METSIM	Adipose	POLR2L	0.03	0.02	bslmm	413	0.01	5.0e-03	-3.2	-5.7	1.2e-08	0.60	0.22	0.17	FALSE
13	YFS	Blood	POLR2L	0.26	0.19	bslmm	383	0.30	2.4e-98	-4.6	5.7	1.5e-08	-0.49	0.33	0.66	FALSE
14	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	CHID1	0.06	0.05	blup	67	0.03	2.0e-02	4.4	-5.7	1.3e-08	0.65	0.04	0.25	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CEND1	0.06	0.02	enet	9	0.04	7.7e-06	-4.5	5.1	2.8e-07	-0.63	0.12	0.72	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	TSPAN4	0.09	0.04	enet	9	0.03	1.9e-04	3.1	5.5	3.5e-08	-0.60	0.19	0.59	FALSE