Best TWAS P=7.25e-08 · Best GWAS P=4.39e-12 conditioned to 0.00143
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | STK33 | 0.18 | 0.18 | lasso | 9 | 0.20 | 3.8e-24 | -4.7 | 5.3 | 1.4e-07 | -0.70 | 0.98 | 0.02 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | STK33 | 0.05 | 0.03 | lasso | 2 | 0.03 | 2.5e-04 | -5.6 | 5.4 | 7.2e-08 | -0.45 | 0.46 | 0.14 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | STK33 | 0.14 | 0.08 | lasso | 6 | 0.10 | 1.0e-09 | -4.9 | 5.3 | 1.0e-07 | -0.69 | 0.98 | 0.02 | FALSE |