Best TWAS P=1.34e-08 · Best GWAS P=4.9e-11 conditioned to 3.7e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | POC1B | 0.12 | 0.08 | lasso | 9 | 0.09 | 1.7e-07 | 4.9 | -5.4 | 8.8e-08 | -0.37 | 0.96 | 0.02 | FALSE |
| 2 | GTEx | Adrenal Gland | RP11-981P6.1 | 0.33 | 0.29 | lasso | 3 | 0.19 | 2.2e-07 | 4.9 | 5.5 | 3.4e-08 | 0.30 | 0.98 | 0.02 | FALSE |
| 3 | GTEx | Artery Tibial | POC1B | 0.13 | 0.06 | enet | 29 | 0.06 | 1.7e-05 | 4.9 | -5.4 | 7.1e-08 | -0.42 | 0.42 | 0.40 | FALSE |
| 4 | GTEx | Nerve Tibial | POC1B | 0.30 | 0.18 | lasso | 6 | 0.22 | 1.0e-15 | -4.6 | -5.7 | 1.3e-08 | -0.30 | 0.99 | 0.01 | TRUE |