Best TWAS P=2.98e-08 · Best GWAS P=1.37e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells EBV-transformed lymphocytes | ARPC3 | 0.13 | 0.09 | lasso | 4 | 0.04 | 2.0e-02 | 5.2 | -5.2 | 1.9e-07 | -0.97 | 0.02 | 0.85 | FALSE |
2 | GTEx | Muscle Skeletal | ARPC3 | 0.14 | 0.11 | enet | 23 | 0.10 | 2.2e-10 | 5.0 | -5.1 | 2.8e-07 | -0.94 | 0.02 | 0.98 | FALSE |
3 | GTEx | Muscle Skeletal | IFT81 | 0.08 | 0.08 | lasso | 5 | 0.07 | 1.7e-07 | 5.2 | 5.5 | 3.0e-08 | 0.98 | 0.02 | 0.98 | TRUE |
4 | GTEx | Skin Not Sun Exposed Suprapubic | VPS29 | 0.06 | 0.01 | lasso | 3 | 0.01 | 6.9e-02 | 5.2 | 5.3 | 1.2e-07 | 0.90 | 0.03 | 0.73 | FALSE |
5 | GTEx | Spleen | VPS29 | 0.24 | 0.01 | enet | 14 | 0.04 | 2.9e-02 | 4.0 | 5.1 | 2.7e-07 | 0.88 | 0.03 | 0.69 | FALSE |