[Hub]/) : Traits : Body mass index (BMI) : ← →

chr12:55,677,395-57,406,444

Best TWAS P=8.51e-13 · Best GWAS P=4.83e-13 conditioned to 0.023

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	RPS26	0.48	0.62	lasso	5	0.63	5.9e-99	-5.5	-5.6	2.6e-08	0.52	0.99	0.01	FALSE
2	GTEx	Artery Tibial	RPS26	0.07	0.02	enet	5	0.01	3.5e-02	-5.5	-5.3	1.1e-07	0.51	0.23	0.18	FALSE
3	GTEx	Brain Cortex	SUOX	0.16	0.11	lasso	4	0.10	1.1e-03	-5.3	5.2	2.1e-07	-0.46	0.08	0.12	FALSE
4	GTEx	Brain Putamen basal ganglia	RP11-977G19.11	0.30	0.15	enet	33	0.20	1.5e-05	-6.5	5.6	1.9e-08	-0.66	0.04	0.90	TRUE
5	GTEx	Breast Mammary Tissue	RPS26	0.29	0.05	enet	37	0.12	9.4e-07	-5.5	-6.9	5.1e-12	0.52	0.84	0.15	FALSE
6	GTEx	Breast Mammary Tissue (Female)	RPS26	0.20	0.11	lasso	3	0.10	6.6e-04	-5.3	-7.2	8.5e-13	0.52	0.05	0.23	TRUE
7	GTEx	Cells Transformed fibroblasts	RPS26	0.11	0.08	enet	15	0.09	3.4e-07	-5.6	-5.1	3.0e-07	0.51	0.96	0.03	FALSE
8	GTEx	Colon Sigmoid	SUOX	0.23	0.18	lasso	4	0.15	7.9e-06	-5.3	5.1	2.7e-07	-0.46	0.75	0.16	FALSE
9	GTEx	Esophagus Gastroesophageal Junction	SUOX	0.20	0.16	lasso	5	0.19	2.7e-07	-5.2	5.5	2.9e-08	-0.52	0.65	0.29	FALSE
10	GTEx	Heart Atrial Appendage	SUOX	0.09	0.10	enet	8	0.09	1.1e-04	-5.5	5.2	2.3e-07	-0.45	0.29	0.21	FALSE
11	GTEx	Muscle Skeletal	RAB5B	0.29	0.32	lasso	4	0.33	1.3e-33	-6.0	6.2	5.1e-10	-0.63	0.86	0.14	FALSE
12	GTEx	Muscle Skeletal	AC034102.1	0.28	0.31	lasso	4	0.31	2.3e-31	-6.0	6.2	5.1e-10	-0.63	0.86	0.14	FALSE
13	GTEx	Prostate	SUOX	0.22	0.04	enet	11	0.05	2.3e-02	-5.2	6.9	4.2e-12	-0.77	0.02	0.86	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	SUOX	0.10	0.14	lasso	2	0.12	2.5e-07	-5.3	5.2	2.0e-07	-0.47	0.79	0.10	FALSE
15	GTEx	Skin Sun Exposed Lower leg	SUOX	0.23	0.30	lasso	3	0.29	1.9e-24	-5.3	5.4	5.7e-08	-0.50	1.00	0.00	FALSE
16	GTEx	Spleen	SUOX	0.34	0.31	enet	15	0.28	5.4e-08	-5.3	6.0	1.8e-09	-0.50	0.48	0.13	FALSE
17	GTEx	Testis	SUOX	0.27	0.18	lasso	14	0.18	1.4e-08	-5.3	5.5	4.1e-08	-0.50	0.82	0.18	FALSE
18	GTEx	Thyroid	SUOX	0.37	0.40	lasso	7	0.38	5.4e-31	-5.3	5.4	7.2e-08	-0.48	1.00	0.00	FALSE
19	GTEx	Whole Blood	RPS26	0.05	0.05	lasso	1	0.05	3.4e-05	-5.2	-5.2	2.1e-07	0.48	0.61	0.12	FALSE
20	METSIM	Adipose	IKZF4	0.04	0.04	enet	3	0.04	1.0e-06	-5.6	-5.6	2.5e-08	0.52	0.98	0.01	FALSE
21	METSIM	Adipose	RPS26	0.30	0.40	lasso	5	0.41	7.2e-66	-5.6	-5.6	2.6e-08	0.52	0.99	0.01	FALSE
22	YFS	Blood	SUOX	0.11	0.09	bslmm	269	0.09	3.4e-27	-5.2	5.2	2.1e-07	-0.54	1.00	0.00	FALSE
23	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RPS26	0.14	0.22	lasso	2	0.23	4.8e-19	-5.6	-5.6	2.1e-08	0.52	0.61	0.39	FALSE
24	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPS26	0.30	0.44	enet	10	0.45	5.2e-104	-5.5	-5.6	1.7e-08	0.52	0.81	0.19	FALSE
25	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RPS26	0.23	0.40	lasso	2	0.39	1.5e-20	-5.5	-5.7	1.4e-08	0.53	0.60	0.40	FALSE
26	The Cancer Genome Atlas	Colon Adenocarcinoma	RPS26	0.43	0.48	lasso	4	0.47	1.8e-30	-5.5	-5.8	7.8e-09	0.54	0.75	0.25	FALSE
27	The Cancer Genome Atlas	Esophageal Carcinoma	RPS26	0.19	0.13	lasso	5	0.11	2.4e-04	-5.5	-5.6	1.7e-08	0.52	0.02	0.93	FALSE
28	The Cancer Genome Atlas	Glioblastoma Multiforme	RPS26	0.41	0.38	enet	9	0.39	7.9e-13	-5.6	-5.6	2.8e-08	0.52	0.40	0.60	FALSE
29	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RPS26	0.17	0.29	lasso	4	0.29	6.2e-33	-5.6	-5.5	3.3e-08	0.51	0.71	0.29	FALSE
30	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RPS26	0.27	0.38	enet	8	0.40	5.0e-24	-5.5	-5.6	2.5e-08	0.53	0.81	0.19	FALSE
31	The Cancer Genome Atlas	Brain Lower Grade Glioma	ERBB3	0.07	0.02	blup	29	0.05	2.1e-06	-6.4	-6.0	2.0e-09	0.79	0.02	0.97	FALSE
32	The Cancer Genome Atlas	Brain Lower Grade Glioma	RPS26	0.31	0.53	enet	8	0.55	1.7e-74	-5.5	-5.7	1.4e-08	0.53	0.76	0.24	FALSE
33	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	RPS26	0.18	0.31	lasso	2	0.29	3.9e-14	-5.5	-5.4	5.1e-08	0.50	0.78	0.22	FALSE
34	The Cancer Genome Atlas	Lung Adenocarcinoma	RPS26	0.26	0.45	enet	9	0.47	3.6e-61	-5.5	-5.7	9.3e-09	0.54	0.76	0.24	FALSE
35	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RPS26	0.22	0.31	lasso	3	0.31	1.6e-35	-5.5	-5.7	1.2e-08	0.54	0.81	0.19	FALSE
36	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RPS26	0.30	0.20	lasso	4	0.24	3.9e-16	-5.5	-5.8	6.0e-09	0.57	0.22	0.78	FALSE
37	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RPS26	0.36	0.44	lasso	7	0.42	2.4e-19	-5.6	-5.3	1.0e-07	0.50	0.75	0.25	FALSE
38	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	RPS26	0.47	0.43	lasso	2	0.44	3.2e-19	-5.2	-5.4	7.9e-08	0.50	0.87	0.13	FALSE
39	The Cancer Genome Atlas	Prostate Adenocarcinoma	RPS26	0.33	0.52	enet	9	0.54	5.6e-66	-5.5	-5.8	7.5e-09	0.55	0.80	0.20	FALSE
40	The Cancer Genome Atlas	Rectum Adenocarcinoma	RPS26	0.24	0.18	lasso	2	0.20	1.9e-05	-5.5	-5.4	5.1e-08	0.50	0.06	0.46	FALSE
41	The Cancer Genome Atlas	Soft Tissue Sarcoma	RPS26	0.23	0.31	lasso	3	0.30	2.4e-18	-5.5	-5.6	2.5e-08	0.51	0.72	0.28	FALSE
42	The Cancer Genome Atlas	Skin Cutaneous Melanoma	RPS26	0.28	0.15	lasso	2	0.17	3.0e-05	-5.9	-5.8	5.1e-09	0.59	0.02	0.93	FALSE
43	The Cancer Genome Atlas	Stomach Adenocarcinoma	RPS26	0.19	0.32	lasso	5	0.34	2.0e-25	-5.6	-5.7	1.2e-08	0.53	0.72	0.28	FALSE
44	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RPS26	0.46	0.64	lasso	4	0.65	8.5e-30	-5.5	-5.8	6.2e-09	0.54	0.37	0.63	FALSE
45	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	RPS26	0.17	0.19	lasso	4	0.18	1.3e-05	-5.5	-5.5	4.4e-08	0.51	0.07	0.89	FALSE