[Hub]/) : Traits : Body mass index (BMI) : ← →

chr12:121,194,565-125,270,773

Best TWAS P=1.47e-14 · Best GWAS P=5.82e-16 conditioned to 0.0877

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	GTEx	Esophagus Mucosa	HIP1R	0.21	0.05	lasso	5	0.07	1.5e-05	4.5	7.7	1.5e-14	-0.21	0.47	0.26	TRUE
25	The Cancer Genome Atlas	Stomach Adenocarcinoma	MLXIP	0.06	0.02	blup	68	0.04	1.2e-03	6.0	7.2	7.8e-13	-0.23	0.02	0.88	TRUE
4	GTEx	Adipose Visceral Omentum	CCDC92	0.19	0.02	lasso	8	0.09	3.3e-05	4.7	7.1	1.7e-12	-0.12	0.06	0.91	TRUE
5	GTEx	Adipose Visceral Omentum	RP11-380L11.3	0.15	0.03	lasso	5	0.01	1.4e-01	4.5	6.7	1.6e-11	-0.08	0.04	0.74	TRUE
10	GTEx	Colon Transverse	SNRNP35	0.18	0.02	lasso	8	0.04	6.5e-03	-4.8	6.7	2.5e-11	-0.16	0.04	0.47	TRUE
11	GTEx	Esophagus Mucosa	KDM2B	0.11	0.04	enet	22	0.10	4.1e-07	2.6	6.0	1.6e-09	-0.10	0.91	0.01	TRUE
8	GTEx	Cells Transformed fibroblasts	BCL7A	0.06	0.01	lasso	4	0.01	3.1e-02	3.7	-5.9	4.5e-09	0.24	0.09	0.05	TRUE
19	METSIM	Adipose	ABCB9	0.04	0.03	enet	19	0.03	7.7e-05	-6.3	-6.8	9.5e-12	0.38	0.08	0.65	FALSE
1	CommonMind	Brain Pre-frontal Cortex	HIP1R	0.06	0.02	lasso	6	0.04	1.9e-05	-6.3	-6.4	1.5e-10	0.09	0.18	0.02	FALSE
2	GTEx	Adipose Subcutaneous	CCDC92	0.23	0.04	enet	27	0.16	6.9e-13	-3.8	6.4	1.5e-10	-0.09	0.05	0.94	FALSE
3	GTEx	Adipose Subcutaneous	RP11-380L11.3	0.09	0.03	lasso	3	0.03	1.4e-03	4.6	6.3	3.6e-10	-0.07	0.09	0.86	FALSE
14	GTEx	Lung	CCDC92	0.14	0.00	enet	10	0.01	1.1e-01	5.3	6.0	1.8e-09	-0.08	0.02	0.89	FALSE
7	GTEx	Breast Mammary Tissue (Female)	C12orf65	0.06	0.00	enet	13	-0.01	6.5e-01	-3.9	-6.0	2.0e-09	0.27	0.05	0.06	FALSE
23	The Cancer Genome Atlas	Colon Adenocarcinoma	MLXIP	0.06	0.04	lasso	7	0.02	2.7e-02	6.0	6.0	2.6e-09	-0.17	0.02	0.94	FALSE
20	METSIM	Adipose	CCDC92	0.10	0.01	bslmm	435	0.06	5.5e-10	-2.9	5.9	3.2e-09	-0.08	0.04	0.95	FALSE
21	METSIM	Adipose	RP11-214K3.24	0.05	0.03	bslmm	444	0.02	2.7e-04	3.7	5.8	5.2e-09	-0.07	0.11	0.79	FALSE
17	GTEx	Thyroid	CCDC92	0.06	0.03	lasso	3	0.02	1.1e-02	4.6	5.8	5.6e-09	-0.08	0.08	0.84	FALSE
9	GTEx	Colon Transverse	MLXIP	0.20	0.18	enet	23	0.14	5.8e-07	6.1	5.7	1.1e-08	-0.17	1.00	0.00	FALSE
24	The Cancer Genome Atlas	Rectum Adenocarcinoma	MLXIP	0.18	0.14	lasso	4	0.13	5.1e-04	5.3	5.7	1.4e-08	-0.16	0.02	0.89	FALSE
16	GTEx	Nerve Tibial	KNTC1	0.12	0.05	lasso	5	0.05	1.9e-04	-5.1	-5.6	2.8e-08	0.31	0.53	0.03	FALSE
13	GTEx	Heart Atrial Appendage	RP11-380L11.4	0.18	0.11	lasso	7	0.12	6.5e-06	4.7	5.5	4.7e-08	-0.07	0.09	0.87	FALSE
15	GTEx	Nerve Tibial	CCDC92	0.16	0.01	enet	6	0.04	6.7e-04	3.5	5.3	1.1e-07	-0.10	0.09	0.47	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	VPS33A	0.06	0.00	enet	8	0.03	9.6e-04	4.1	-5.3	1.2e-07	0.20	0.10	0.88	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	DNAH10	0.11	0.03	blup	99	0.05	8.2e-11	5.0	5.3	1.4e-07	-0.05	0.03	0.96	FALSE
18	GTEx	Whole Blood	DDX55	0.13	0.04	enet	13	0.06	3.3e-06	-3.9	5.2	1.7e-07	-0.17	0.22	0.27	FALSE
6	GTEx	Artery Tibial	PITPNM2	0.11	0.05	lasso	4	0.04	2.7e-04	-4.8	5.2	1.8e-07	0.00	0.60	0.16	FALSE