[Hub]/) : Traits : Body mass index (BMI) :

chr1:106,906,072-108,724,766

Best TWAS P=2.87e-09 · Best GWAS P=3.18e-09 conditioned to 1.52e-10

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PRMT6 0.19 0.16 lasso 6 0.16 5.4e-19 5.58 -5.6 2.5e-08 -0.08 0.03 0.97 FALSE
2 GTEx Adipose Subcutaneous PRMT6 0.17 0.10 enet 6 0.11 5.1e-09 5.09 -5.5 4.0e-08 -0.09 0.04 0.96 FALSE
3 GTEx Colon Transverse PRMT6 0.29 0.24 lasso 7 0.19 1.4e-09 5.37 -5.7 1.4e-08 -0.09 0.04 0.96 FALSE
4 GTEx Esophagus Mucosa PRMT6 0.33 0.23 lasso 7 0.29 1.4e-19 5.48 -5.5 3.0e-08 -0.08 0.04 0.96 FALSE
5 GTEx Heart Left Ventricle PRMT6 0.16 0.12 enet 9 0.13 2.3e-07 5.36 -5.9 2.9e-09 -0.12 0.04 0.95 TRUE
6 GTEx Liver PRMT6 0.60 0.52 lasso 6 0.58 1.0e-19 5.37 -5.8 7.5e-09 -0.08 0.03 0.97 FALSE
7 GTEx Lung PRMT6 0.11 0.14 lasso 2 0.13 2.2e-10 5.48 -5.5 4.2e-08 -0.10 0.03 0.97 FALSE
8 GTEx Muscle Skeletal PRMT6 0.32 0.16 enet 13 0.16 2.8e-15 5.48 -5.9 3.7e-09 -0.08 0.03 0.97 FALSE
9 GTEx Skin Not Sun Exposed Suprapubic PRMT6 0.46 0.35 lasso 6 0.37 2.1e-21 5.48 -5.5 4.1e-08 -0.09 0.03 0.97 FALSE
10 GTEx Skin Sun Exposed Lower leg PRMT6 0.40 0.36 lasso 4 0.37 6.1e-32 5.50 -5.5 3.9e-08 -0.09 0.03 0.97 FALSE
11 GTEx Stomach PRMT6 0.29 0.16 enet 7 0.15 8.6e-08 5.58 -5.4 8.3e-08 -0.08 0.03 0.97 FALSE
12 GTEx Thyroid PRMT6 0.19 0.17 enet 14 0.19 1.7e-14 5.45 -5.9 3.9e-09 -0.08 0.04 0.96 FALSE
13 METSIM Adipose NTNG1 0.06 0.02 bslmm 642 0.02 8.6e-04 -0.86 -5.2 2.4e-07 0.05 0.41 0.02 TRUE
14 METSIM Adipose PRMT6 0.21 0.20 lasso 9 0.21 1.1e-30 5.45 -5.5 2.9e-08 -0.08 0.04 0.96 FALSE
15 YFS Blood PRMT6 0.32 0.34 enet 28 0.36 6.6e-123 5.48 -5.2 1.6e-07 -0.10 0.03 0.97 FALSE
16 The Cancer Genome Atlas Bladder Urothelial Carcinoma PRMT6 0.13 0.10 lasso 4 0.10 2.0e-08 5.45 -5.6 2.5e-08 -0.09 0.01 0.99 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma PRMT6 0.10 0.15 lasso 3 0.16 1.2e-30 5.37 -5.5 3.6e-08 -0.09 0.01 0.99 FALSE
18 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma PRMT6 0.09 0.03 blup 36 0.07 1.8e-04 5.36 -5.1 3.0e-07 -0.06 0.01 0.93 FALSE
19 The Cancer Genome Atlas Colon Adenocarcinoma PRMT6 0.19 0.20 lasso 4 0.24 2.4e-14 5.48 -5.5 4.9e-08 -0.09 0.01 0.99 FALSE
20 The Cancer Genome Atlas Esophageal Carcinoma PRMT6 0.33 0.26 lasso 3 0.25 2.0e-08 5.37 -5.6 2.1e-08 -0.09 0.01 0.99 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PRMT6 0.16 0.17 lasso 6 0.17 8.4e-19 5.48 -5.5 5.0e-08 -0.09 0.01 0.99 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PRMT6 0.08 0.11 lasso 4 0.11 1.1e-12 5.48 -5.5 4.3e-08 -0.10 0.01 0.99 FALSE
23 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PRMT6 0.06 0.08 lasso 3 0.06 1.6e-04 5.48 -5.5 4.6e-08 -0.09 0.01 0.98 FALSE
24 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PRMT6 0.29 0.28 lasso 4 0.28 2.6e-13 5.36 -5.3 1.2e-07 -0.09 0.01 0.99 FALSE
25 The Cancer Genome Atlas Lung Adenocarcinoma PRMT6 0.17 0.22 lasso 3 0.22 4.8e-25 5.36 -5.4 6.3e-08 -0.09 0.01 0.99 FALSE
26 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PRMT6 0.11 0.12 enet 7 0.12 2.3e-13 5.48 -5.6 1.9e-08 -0.09 0.01 0.99 FALSE
27 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PRMT6 0.09 0.08 blup 36 0.08 3.3e-06 5.45 -5.9 2.9e-09 -0.09 0.01 0.99 FALSE
28 The Cancer Genome Atlas Stomach Adenocarcinoma PRMT6 0.17 0.17 enet 6 0.19 1.5e-13 5.48 -5.5 3.4e-08 -0.09 0.01 0.99 FALSE