Hub : Genes

NTNG1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.0600	0.0253	4.5e-03	0.019	0.010	0.016	0.018	0.018	0.00059	1.1e-02	1.6e-03	0.00086	9.3e-04
2	ROSMAP	Brain Pre-frontal Cortex	0.0751	0.0292	7.1e-03	-0.002	0.015	0.005	0.015	-0.001	1.00000	4.3e-03	7.2e-02	0.00380	5.3e-01
3	TCGA	Breast Invasive Carcinoma	0.0330	0.0131	1.4e-03	0.010	0.011	0.005	NA	0.008	0.00280	2.2e-03	2.3e-02	NA	7.7e-03
4	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1280	0.0530	6.9e-03	-0.003	0.015	0.011	NA	-0.002	0.58000	4.6e-02	7.2e-02	NA	4.7e-01
5	TCGA	Lung Squamous Cell Carcinoma	0.0936	0.0376	4.0e-03	0.003	0.008	-0.002	NA	-0.002	0.12000	3.4e-02	8.6e-01	NA	9.0e-01
6	TCGA	Prostate Adenocarcinoma	0.0704	0.0258	1.3e-03	0.005	0.030	-0.002	NA	0.002	0.09800	3.4e-04	6.2e-01	NA	1.7e-01
7	TCGA	Stomach Adenocarcinoma	0.1890	0.0480	1.6e-06	0.017	0.070	0.052	NA	0.057	0.02000	9.4e-06	1.1e-04	NA	5.9e-05
8	TCGA	Thyroid Carcinoma	0.0650	0.0260	3.0e-03	0.045	0.021	0.042	NA	0.039	0.00003	3.3e-03	5.9e-05	NA	1.1e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.6	1.0	3.4	0.6	-1.0	0.6	-0.4	-1.5	-0.4	-1.8	0.7
Bipolar Disorder or Schizophrenia	1.0	2.3	7.9	-0.4	-1.5	-0.8	-1.8	-2.8	-0.1	-2.0	-0.3
Depressed Affect (Nagel 2018)	1.0	2.0	11.3	-3.4	-0.3	-0.3	-1.5	1.0	-0.1	-0.7	-0.9
Depression (Nagel 2018)	2.4	3.6	9.4	-2.0	-1.6	-3.1	-2.3	-1.6	0.3	-2.1	-0.8
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.0	0.0	-1.0	0.5	1.4	-0.1	1.4	0.1	0.6
Neuroticism (Nagel 2018)	1.0	2.3	11.4	-3.4	-1.5	-0.2	-1.5	-0.6	-0.6	-0.7	-0.9
Schizophrenia (2018)	1.0	2.1	5.3	-1.0	-1.2	-1.7	-2.1	-2.3	0.2	-1.1	-0.9
Schizophrenia vs Biploar Disorder	0.3	0.4	2.3	-0.9	-0.2	0.1	-1.5	-0.3	0.2	0.2	-0.4
Worry (Nagel 2018)	0.3	0.7	2.2	-1.3	-1.5	0.3	-0.3	-1.0	-0.5	-0.4	0.1
Alzheimer’s Disease (in mother)	0.8	0.9	2.3	-0.5	-0.9	0.1	-1.2	-1.5	-1.2	0.8	-0.7
Alzheimer’s Disease (in father)	3.7	4.0	8.4	1.0	1.6	2.1	2.9	2.9	0.4	2.2	1.4
Alzheimer’s Disease (including proxy)	0.4	0.6	2.4	-0.3	-0.5	1.0	-0.3	0.4	-0.8	1.6	-0.0
Crohns Disease (2017)	0.6	1.2	2.6	-0.2	-1.2	-1.2	-1.6	-1.3	0.3	-1.6	-0.4
Irritable Bowel Disease (IBD)	0.2	0.5	1.9	0.1	-1.4	-0.0	-0.2	-1.1	0.8	-0.3	0.2
Ulcerative Colitis (UC)	0.4	0.7	1.8	0.6	-0.9	1.3	0.7	-0.3	0.9	1.0	0.4
Major Depression (MDD)	1.3	1.6	6.8	-2.6	1.8	-0.3	-1.4	0.5	0.5	0.4	-0.2
Reaction Time	0.4	0.7	3.8	0.3	-0.3	-0.6	0.1	-1.1	0.4	-2.0	-0.4
Verbal and Numeric Reasoning (VNR)	0.9	2.1	4.7	0.5	-1.1	1.2	1.9	2.2	2.0	-1.0	0.7
Breast Cancer	0.3	0.8	1.8	1.2	1.2	-0.9	0.9	0.5	1.3	-0.2	0.0
Ovarian Cancer	2.7	3.5	8.7	2.5	1.7	0.9	1.7	1.8	2.9	1.3	1.3
Prostate Cancer	1.0	1.3	3.0	-0.1	-1.2	-1.5	0.8	0.0	0.6	-1.7	-1.7
Age at First Birth	0.7	1.0	3.2	-0.2	-0.0	0.2	1.8	0.7	1.6	0.2	1.3
Bipolar Disorder (2011)	0.6	0.6	1.6	-1.0	1.0	0.5	-0.5	-0.6	-0.2	-1.3	0.0
Body Mass Index (BMI) (2010)	1.0	1.4	3.2	-1.2	-0.9	-1.5	-1.0	0.6	0.0	-1.4	-1.8
Coronary Artery Disease (CAD)	0.9	1.0	4.6	0.6	0.5	0.1	-0.5	-1.2	2.1	0.4	1.1
Crohns Disease (2012)	0.5	0.8	2.3	-1.0	-1.2	-1.5	-0.6	-0.3	1.2	-0.4	0.3
Mean Putamen Volume	1.4	1.5	5.2	0.6	1.2	-0.7	-0.9	-2.3	-0.8	-1.5	-1.1
Fasting Glucose	0.2	0.2	1.0	0.4	0.0	0.3	-0.5	-0.1	-1.0	-0.7	-0.1
HbA1C	1.6	1.8	4.8	-2.2	-0.2	-0.6	-2.0	-0.6	-0.8	-2.1	-0.3
HDL Cholesterol	0.6	1.0	6.6	-0.0	-0.7	-0.4	-0.2	-2.6	-0.5	-0.1	0.6
LDL Cholesterol	0.6	1.0	1.4	-0.9	1.1	-1.2	-1.1	0.1	-1.2	-0.7	-1.1
Lupus	0.3	0.5	2.4	-0.2	0.1	1.6	0.6	-0.3	0.4	0.2	1.1
Neuroticism (2016)	3.0	4.3	7.6	-2.6	-0.2	-2.1	-2.8	-1.9	-2.3	-1.3	-2.2
Primary Biliary Cirrhosis	1.5	2.1	8.0	-0.8	-2.8	0.4	-0.1	-2.3	-1.2	-0.9	-0.5
Rheumatoid Arthritis	3.6	4.9	16.9	-4.1	-2.6	-0.1	-1.6	-2.2	-2.2	-1.7	-0.7
Schizophrenia (2014)	0.9	2.0	7.3	-1.1	-0.9	-0.7	-2.7	-2.1	-0.6	-0.8	-1.0
Triglycerides	0.8	1.3	3.9	1.1	1.0	0.7	0.5	2.0	1.1	1.4	0.8
Type 2 Diabetes (T2D) (2012)	0.8	0.9	3.3	-0.6	-0.8	-0.2	0.7	-0.4	1.8	-1.5	0.2
Ulcerative Colitis	0.6	0.9	3.5	0.0	-1.9	0.7	0.4	-0.9	0.6	0.6	1.2
Blood Eosinophil Count	0.1	1.1	4.8	-0.6	1.3	-0.5	0.2	0.6	0.2	-2.2	-1.0
Blood Platelet Count	0.1	0.7	2.7	-0.4	1.2	-0.6	-0.6	-1.6	-0.5	-0.1	-0.5
Blood Red Count	0.1	1.3	6.6	0.8	-2.6	0.2	-0.7	0.7	0.6	-1.2	-0.6
Blood White Count	0.4	2.7	11.7	-3.4	0.4	-1.8	-0.3	-1.0	-1.3	-1.2	-1.3
Heel T-Score	0.1	0.7	2.4	0.0	-1.6	0.6	0.4	-0.9	-0.7	1.1	0.1
BMI	0.9	4.9	20.4	-4.5	1.1	-0.4	-2.0	1.8	0.5	-2.7	-1.7
Height	0.0	0.9	2.7	-0.2	-1.6	-0.9	-0.2	0.9	-0.3	-0.1	-1.6
Waist Hip Ratio (WHR)	0.2	0.8	3.5	0.4	1.9	-0.3	-0.9	-0.8	0.7	0.0	1.0
Systolic Blood Pressure	0.2	0.9	3.3	1.8	0.7	0.8	-0.9	-1.0	0.8	0.5	0.1
Smoking Status	0.9	2.1	5.2	-1.0	1.7	-2.3	-0.2	-1.1	-0.7	-1.3	-2.1
Allergy or Eczema	1.0	2.7	8.0	-2.8	-2.1	0.3	-0.2	-0.8	-2.1	-1.5	-1.3
Cardiovascular Disease	0.3	0.9	4.1	-2.0	0.6	1.1	-0.2	1.1	0.6	0.0	0.4
Hypothyroidism (self reported)	0.7	1.5	7.9	-2.8	-0.6	1.1	-0.7	1.1	0.3	0.9	0.4
Respiratory disease	0.6	1.4	4.2	-0.8	1.1	-1.7	-0.6	-2.1	-0.2	-1.4	0.1
Type 2 Diabetes (T2D) (2018)	0.8	1.5	5.0	-1.4	0.9	-0.9	-0.0	0.6	2.2	-1.8	-0.3
Lung FEV1/FVC ratio	0.2	0.9	3.4	-1.6	-1.8	0.8	-0.7	0.2	0.3	-0.0	0.3
Lung FVC	0.5	2.5	5.4	1.7	0.2	1.7	1.9	-1.3	0.2	2.3	1.9
Neuroticism	0.3	0.8	5.2	-2.3	-0.2	-0.1	-0.7	0.0	-0.5	0.0	-0.3
Chronotype (morning person)	0.6	1.3	4.8	-1.0	0.8	0.2	-0.6	-1.7	-2.2	0.8	-0.1
Hair Pigment	0.0	0.9	1.9	-0.7	-0.6	1.3	1.4	-0.0	1.4	0.0	0.8
Tanning	0.0	0.4	0.8	-0.3	0.5	0.2	0.6	-0.9	-0.7	0.9	0.4
Hand grip strength (left)	0.4	1.1	2.5	-0.6	1.4	0.2	1.0	1.6	1.6	0.4	0.2
Number of treatments/medications taken	0.7	1.2	5.5	-2.4	0.3	-0.2	-1.1	-0.1	0.1	-1.7	-0.5
Average weekly spirits intake	1.0	1.2	4.2	-2.0	1.1	-1.1	-0.4	1.1	-0.7	0.5	-1.1
Sensitivity / hurt feelings	0.4	0.6	3.4	-1.8	-0.1	-0.7	-0.7	-0.2	-0.3	-0.6	-0.5
Frequency of depressed mood in last 2 weeks	1.9	2.6	7.8	-1.4	-1.1	-2.5	-1.1	-1.0	1.0	-2.8	-0.6
Hearing difficulty/problems: Yes	0.4	0.5	1.8	-0.5	-0.2	0.3	0.7	-1.3	-1.1	-0.4	-0.6
Relative age of first facial hair	0.2	0.3	0.9	-0.2	-0.9	-0.2	1.0	0.8	-0.5	0.2	0.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.5	-0.0	-0.2	0.4	0.5	0.4	0.2	-0.7	-0.3
Ever used hormone-replacement therapy (HRT)	1.7	2.1	8.4	-1.0	-2.9	0.6	-0.7	-0.8	-2.3	-0.9	-0.6
Ever had hysterectomy (womb removed)	0.2	0.3	0.7	-0.5	-0.1	-0.7	0.5	-0.8	-0.7	-0.2	-0.1
Systolic blood pressure, automated reading	0.2	0.6	1.6	1.3	-0.2	-0.1	-1.1	-1.2	-0.4	-0.5	-0.5
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	3.3	-1.8	-0.4	-0.5	-1.8	-0.3	0.1	-0.5	-0.7
Angina	0.5	0.7	1.5	0.5	1.2	-0.0	0.3	1.2	1.2	0.2	-0.9
Medication for hormone replacement therapy	0.3	0.3	1.2	0.7	0.2	-0.4	1.1	0.5	0.2	0.2	0.0
Vitamin and mineral supplements	1.3	1.8	4.4	1.8	2.0	0.3	0.6	0.9	0.9	2.1	0.9
Supplements: Zinc	3.6	3.9	10.4	-1.4	-1.6	-1.4	-1.5	-3.2	-1.9	-2.9	-0.7
Medication: Co-codamol	0.3	0.4	1.2	0.0	-0.5	0.3	-0.3	-1.1	-0.9	-0.7	-0.3
Medication: Metformin	1.7	2.4	4.4	-1.3	0.3	-1.9	-1.6	1.1	1.3	-2.1	-1.9
Diabetes (father)	1.6	2.0	7.9	0.7	-0.1	1.0	1.3	2.8	0.8	2.1	-0.2
Diabetes (mother)	0.7	0.9	3.6	-0.6	-1.9	0.2	1.0	-1.1	-0.1	-1.0	0.3
Severe depression (siblings)	0.9	1.0	3.0	-0.6	-0.0	0.7	-0.9	-0.4	-1.7	1.4	-0.9
Pack years adult smoking proportion	1.0	1.5	3.3	-1.4	1.8	-1.7	-0.9	-0.0	0.3	-1.1	-1.3
Impedance of leg (right)	1.2	5.9	21.6	4.7	0.8	1.7	1.8	-0.5	-0.4	3.2	2.9
Leg fat-free mass (left)	1.0	5.4	20.5	-4.5	-1.0	-1.1	-1.0	2.0	1.2	-2.8	-2.5
Trunk fat percentage	1.1	4.5	17.3	-4.2	1.2	-1.4	-2.1	1.0	-0.9	-2.0	-2.4
Hand grip strength (right)	0.2	0.5	1.4	-0.5	0.9	0.0	-0.1	1.2	1.0	-0.3	0.1
Townsend deprivation index at recruitment	1.7	2.4	4.4	-2.1	1.0	-1.9	-1.6	-1.3	-1.3	-1.2	-1.5
Current tobacco smoking	1.8	2.9	7.2	-1.2	2.5	-2.7	-0.3	-0.3	0.7	-1.8	-2.0
Average weekly fortified wine intake	0.3	0.4	1.3	-1.1	0.4	-0.7	-0.3	-0.3	0.1	0.4	-1.0
Maternal smoking around birth	0.4	0.6	2.2	-0.9	0.1	-0.2	-1.5	-0.7	-0.5	-1.0	0.3
Fed-up feelings	0.5	0.9	2.4	-1.6	0.3	-0.6	-1.2	-0.9	0.6	-1.2	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	2.6	3.5	8.9	-0.5	-0.8	-2.8	-2.0	-1.5	1.1	-3.0	-1.6
Relative age voice broke	0.7	1.1	3.3	-0.0	-1.4	1.0	0.1	1.8	0.2	1.0	1.3
Taking other prescription medications	0.6	0.9	3.0	-1.7	-1.0	0.3	-1.4	-0.1	-0.8	-0.7	-0.5
Age when periods started (menarche)	0.2	0.6	1.7	-0.2	-1.0	1.3	-0.4	-0.5	-1.1	0.4	0.3
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	4.3	-1.3	-1.3	-0.8	-0.8	-0.6	-2.1	-1.7	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	3.6	-1.3	-0.1	-1.2	-0.3	-0.2	-0.4	-1.9	-0.5
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.8	-0.9	-0.5	0.1	0.2	0.6	-0.2	-0.9	-0.4
Qualifications: CSEs or equivalent	0.6	0.8	2.9	-0.1	0.2	0.4	-0.2	1.3	0.9	0.9	1.7
Serious illness, injury or assault to yourself	0.7	0.8	2.0	-0.5	-0.2	-1.0	-1.4	-1.0	0.8	-1.1	-0.8
High blood pressure	0.6	1.7	4.6	-2.1	-0.7	0.3	-1.6	-0.8	-1.4	-1.7	-0.8
Hayfever, allergic rhinitis or eczema	1.3	2.9	11.1	-3.3	-1.3	0.7	-0.0	-1.3	-2.7	-0.7	-0.8
Multivitamins +/- minerals	0.8	1.0	3.0	-1.0	-0.6	-0.5	-0.5	-1.0	-1.3	-1.7	-0.7
Stomach or abdominal pain in last month	0.1	0.2	0.4	-0.6	0.4	-0.3	-0.4	0.1	-0.5	0.2	-0.2
Supplements: Glucosamine	1.0	1.3	3.4	-1.1	-0.3	-0.4	-0.2	-1.7	-1.8	-1.4	-0.7
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	3.7	-1.5	-0.3	-1.3	-1.8	0.3	0.1	0.4	-1.9
Medication: Atenolol	0.6	0.7	1.7	0.9	1.3	-1.1	-0.6	-0.5	0.3	-0.5	-0.9
Medication: Levothyroxine sodium	0.5	0.9	4.9	-2.2	-0.4	1.0	-0.7	0.5	0.0	0.1	-0.1
Sitting height	0.2	1.2	3.7	-1.2	-1.2	-0.3	-0.4	1.9	0.2	-0.6	-1.6
Chronic bronchitis/emphysema (father)	1.3	1.5	2.5	-1.5	0.7	-0.9	-1.4	-0.2	-1.5	-1.6	-1.4
High blood pressure (mother)	0.4	0.6	2.1	-1.5	1.1	-0.8	-0.4	-0.6	-0.2	-0.0	-0.6
Body mass index (BMI)	1.4	6.1	26.7	-5.2	0.6	-1.1	-1.9	1.2	0.0	-2.9	-2.7
Impedance of leg (left)	1.0	4.8	19.2	4.4	1.1	1.1	1.2	-0.7	-0.5	3.0	2.4
Leg predicted mass (left)	1.0	5.4	20.8	-4.6	-1.0	-1.1	-0.9	2.0	1.1	-2.8	-2.5
Trunk fat mass	1.3	5.7	22.4	-4.7	0.7	-1.5	-1.8	1.4	-0.4	-2.6	-2.9
Waist circumference	1.3	4.7	18.7	-4.3	1.4	-1.1	-1.6	1.4	0.0	-2.5	-2.2
Number of incorrect matches in round	0.5	0.9	1.8	0.0	-1.2	-0.6	-0.4	-1.4	-1.0	-1.0	-1.2
Past tobacco smoking	0.1	0.2	1.0	-0.0	-0.3	1.0	-0.3	0.4	0.3	-0.3	0.6
Alcohol usually taken with meals	1.0	1.7	7.7	-0.3	-2.8	0.4	1.7	1.1	-0.6	1.0	-0.1
Nervous feelings	0.8	1.5	3.6	-1.4	-1.9	-0.7	-1.2	-1.5	-0.6	-1.4	-0.3
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.1	4.0	-0.7	-1.8	-1.8	-1.9	-1.2	0.6	-2.0	-0.9
Hearing difficulty/problems with background noise	0.5	0.8	1.3	-1.0	-1.1	0.1	0.1	-1.0	-1.1	-0.8	-1.1
Hair/balding pattern: Pattern 2	0.6	0.8	1.9	0.7	-0.4	1.2	1.4	0.7	0.5	0.6	1.0
Had menopause	1.5	1.9	6.4	1.3	0.1	-1.1	-1.4	-2.5	-1.5	-0.6	-1.2
Had other major operations	1.5	1.8	5.0	1.4	-1.4	2.2	0.8	1.5	0.2	0.2	1.5
Forced vital capacity (FVC)	0.4	1.5	3.1	0.5	-1.4	1.4	1.8	0.4	1.0	0.8	1.8
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.9	-1.3	0.3	-1.3	-0.2	0.0	-0.2	-1.4	-0.4
Ever unenthusiastic/disinterested for a whole week	1.9	2.3	6.6	-1.9	-0.1	-2.0	-2.6	-1.0	-0.0	-1.1	-1.5
Qualifications: None of the above	3.6	7.6	15.3	-3.0	-0.5	-2.5	-3.9	-2.8	-2.1	-3.1	-2.9
Financial difficulties in last 2 years	0.2	0.2	0.7	-0.3	0.0	-0.4	-0.3	-0.7	0.5	-0.8	0.2
Mouth/teeth dental problems	0.6	1.0	5.0	0.8	0.1	-0.9	-0.8	0.3	2.2	0.5	-0.5
Heart attack	0.2	0.3	1.0	-0.6	0.6	-0.0	-1.0	0.1	0.9	0.2	-0.1
Allergy	1.6	3.6	10.9	3.3	0.8	1.0	1.4	2.4	2.5	1.4	0.6
Pain all over the body in last month	1.2	1.3	2.6	-1.4	0.2	0.4	-1.4	-1.0	-1.6	-1.6	-0.1
Diabetes (self-reported)	1.7	2.6	7.9	-1.3	-0.0	-1.9	-1.2	0.6	1.9	-2.8	-1.5
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	3.2	-0.4	-0.0	1.6	1.7	0.6	-0.8	1.8	0.7
Medication: Ramipril	0.8	1.0	5.2	-0.8	-2.3	0.1	0.0	-1.1	0.4	-0.9	-0.1
Medication: Simvastatin	0.8	1.2	4.2	-2.0	1.3	-1.0	-0.1	0.5	0.5	-1.0	-1.0
Fluid intelligence score	1.1	2.4	5.4	0.8	-0.9	1.4	1.9	2.3	2.2	-0.0	1.3
Illnesses of siblings	0.3	0.4	1.4	0.4	0.5	0.7	1.2	0.7	0.6	0.5	0.2
Neuroticism score	0.3	0.6	4.0	-2.0	-0.0	-0.1	-0.7	0.1	-0.2	-0.3	0.0
Weight	1.2	5.8	23.2	-4.8	0.1	-1.2	-1.3	1.9	0.5	-2.8	-2.9
Impedance of arm (right)	0.7	3.2	10.4	3.2	-0.0	0.9	2.0	-0.8	0.4	1.8	2.5
Arm fat percentage (right)	1.3	4.9	21.0	-4.6	0.3	-1.2	-1.6	0.6	-0.3	-2.7	-2.5
Trunk fat-free mass	0.6	3.6	10.1	-3.2	-1.0	-0.8	0.0	2.1	1.1	-2.3	-2.5
Hip circumference	1.1	4.7	22.2	-4.7	0.2	-0.3	-0.7	2.7	0.0	-1.8	-2.0
Time employed in main current job	0.3	0.4	2.1	1.5	-0.2	-0.4	-0.5	-0.3	0.1	0.6	-0.5
Alcohol intake versus 10 years previously	0.6	0.9	2.3	-0.8	-1.5	-1.0	-0.3	-1.4	-0.3	-0.5	-0.8
Father’s age at death	0.3	0.4	1.9	-0.2	-1.4	-0.6	0.5	-0.0	0.5	-0.6	-0.3
Worrier / anxious feelings	0.4	0.7	1.9	-1.4	-1.0	0.4	-0.7	-1.0	-0.3	0.0	1.1
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.1	7.3	-1.8	0.9	-1.5	-2.7	-1.7	-0.3	-2.6	-1.1
Falls in the last year	5.1	6.9	16.4	-3.3	1.2	-3.1	-2.2	-1.7	-1.5	-2.6	-4.0
Hair/balding pattern: Pattern 3	0.1	0.2	0.6	-0.6	-0.3	-0.6	-0.2	0.1	-0.4	0.8	-0.0
Number of live births	1.1	1.6	4.7	0.9	2.2	1.3	0.3	0.0	1.7	1.6	0.4
Forced expiratory volume in 1-second (FEV1)	0.7	2.3	5.0	0.5	-1.9	1.8	1.5	0.2	1.2	1.4	2.2
Pulse rate	0.4	0.6	2.1	-1.0	-1.4	-0.1	-1.0	-0.7	0.3	0.0	0.0
Happiness	0.6	0.7	2.4	1.1	-0.6	0.6	-0.4	1.0	1.5	0.0	0.6
Noisy workplace	0.9	1.1	2.5	-0.7	1.0	-0.9	0.0	-1.5	-1.6	-0.6	-1.2
Qualifications: A levels/AS levels or equivalent	2.8	6.2	14.0	3.0	-2.0	2.8	3.2	1.1	1.8	0.6	3.7
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.8	4.2	2.0	-0.5	1.4	1.8	1.5	0.3	1.4	0.5
Mouth/teeth dental problems: Dentures	1.2	2.0	5.8	-0.2	0.8	-1.7	-1.7	-0.5	-1.7	-0.6	-2.4
Asthma	1.2	2.3	6.6	-1.6	-0.3	-1.6	-1.1	-2.3	-0.5	-2.6	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	1.9	1.2	0.7	0.1	0.9	-0.3	1.4	1.0	0.2
Medication: Cholesterol lowering	0.8	1.3	5.2	-1.1	0.3	-1.1	-1.1	-0.6	0.9	-2.3	-0.3
Depression (self-reported)	1.3	1.6	5.4	-1.7	-0.9	-0.4	-2.3	0.4	-0.3	-0.5	-1.6
Medication: Lansoprazole	1.1	1.2	4.2	0.1	-1.1	-0.1	-2.0	-1.3	-1.2	-0.9	-0.7
Prospective memory result	0.8	1.0	3.2	1.8	-0.2	-0.4	-0.2	-1.4	0.7	0.3	1.4
Lung cancer (father)	0.4	0.5	2.5	-0.5	0.6	0.3	-0.0	-0.1	-0.1	-0.9	1.6
Illnesses of mother	0.7	0.9	3.0	1.7	0.0	-0.2	0.8	1.0	1.2	0.0	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	5.4	1.1	-1.5	1.9	1.6	-0.1	1.0	1.1	2.3
Pulse wave Arterial Stiffness index	1.5	1.8	4.3	-1.8	-1.5	-0.9	-0.7	-0.6	-2.1	-0.1	-1.6
Impedance of arm (left)	0.7	3.0	9.4	3.1	1.0	0.8	1.2	-0.4	0.1	2.5	2.3
Arm fat mass (right)	1.7	6.9	28.8	-5.4	0.2	-1.5	-1.9	1.0	-0.2	-3.2	-3.0
Trunk predicted mass	0.6	3.6	9.9	-3.1	-1.0	-0.8	0.0	2.1	1.2	-2.3	-2.4
Standing height	0.1	0.9	3.4	-0.3	-1.1	-0.5	0.9	1.9	1.0	-0.3	-0.9
Length of working week for main job	1.4	1.6	5.3	-1.4	0.2	-2.3	-1.3	-0.5	-0.8	-0.0	-1.6
Exposure to tobacco smoke at home	1.0	1.1	3.0	1.7	-1.0	-0.0	1.1	-0.4	1.5	1.1	0.4
Breastfed as a baby	0.4	0.5	1.9	0.9	-0.3	0.1	0.5	-0.4	-1.4	-1.0	-0.4
Tense / ‘highly strung’	0.4	0.7	2.1	-0.5	-0.3	0.8	0.8	-0.2	-0.3	1.4	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.5	-0.7	0.3	1.6	-1.2	0.4	-0.6	-0.1	0.2
Hair/balding pattern: Pattern 4	0.5	1.2	4.5	-0.4	-1.1	-0.2	-0.8	-2.1	-1.3	-0.5	-1.0
Birth weight of first child	0.4	0.7	2.0	-1.1	0.4	-0.0	-1.0	0.7	1.4	-0.9	0.1
Peak expiratory flow (PEF)	1.1	2.6	7.7	0.4	-2.8	1.6	0.2	0.8	2.0	0.8	2.2
Pulse wave reflection index	0.8	1.0	5.6	-1.1	0.4	-0.2	-0.1	-0.7	-2.4	-0.4	-0.8
Ever highly irritable/argumentative for 2 days	0.5	0.5	1.4	-1.1	0.7	1.2	0.4	0.0	-0.2	-0.8	0.5
Loud music exposure frequency	0.7	0.8	2.0	-0.5	-1.4	-0.3	-1.1	-1.0	0.7	-0.9	-0.5
Qualifications: O levels/GCSEs or equivalent	2.8	4.4	11.5	2.6	-1.5	3.4	2.8	0.2	0.7	0.3	2.5
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	3.3	-0.5	-0.9	1.3	1.5	0.1	0.3	-0.7	1.8
Blood clot in the leg (DVT)	0.2	0.2	0.5	-0.4	-0.7	-0.6	-0.2	-0.4	0.4	0.5	-0.1
Medication: Paracetamol	1.7	2.8	4.8	1.6	-0.6	1.6	2.2	1.3	2.0	1.3	2.1
Headache pain in last month	0.8	1.3	3.2	-0.2	-1.8	1.2	1.6	-0.4	-1.1	-0.6	1.3
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	4.1	1.5	-1.5	1.9	1.3	0.8	-0.6	2.0	1.1
Glaucoma (self-reported)	0.2	0.2	0.8	-0.0	-0.3	0.8	0.9	0.4	-0.2	0.3	-0.3
Gout (self-reported)	2.4	3.3	7.1	0.6	-0.0	2.1	2.3	2.5	2.7	1.3	1.2
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	5.5	-2.4	-0.6	1.1	-0.6	0.6	-0.3	0.7	-0.3
Medication: Amlodipine	0.4	0.5	1.0	-0.8	-0.8	-0.9	-0.4	-1.0	-0.5	-0.8	-0.2
Medication: Ventolin 100micrograms inhaler	0.8	1.1	2.7	1.3	-0.9	0.0	-1.1	-1.7	-0.1	-0.2	1.5
Birth weight	0.4	0.8	2.7	-1.6	0.9	-0.6	-0.2	0.6	-0.1	-0.9	-1.1
Chronic bronchitis/emphysema (mother)	0.9	1.0	3.2	-1.3	-0.2	-0.4	-1.8	-0.0	-1.2	-0.3	-1.2
High blood pressure (siblings)	0.6	0.9	3.3	-0.1	-1.4	-0.1	-0.1	-0.9	-1.8	-1.1	0.1
Forced vital capacity (FVC), Best measure	0.6	2.1	4.5	1.5	-1.5	1.5	1.9	0.0	1.0	0.8	2.1
Body fat percentage	1.1	4.2	16.2	-4.0	1.1	-1.2	-1.9	1.0	-0.6	-2.0	-2.4
Leg fat percentage (right)	0.8	2.9	12.2	-3.5	0.3	-0.7	-1.1	0.9	-0.5	-1.7	-2.3
Arm fat-free mass (right)	0.9	4.4	16.6	-4.1	-0.2	-1.2	-0.8	2.0	0.2	-2.3	-2.7
Exposure to tobacco smoke outside home	1.0	1.4	4.7	1.0	-1.5	-1.4	-0.6	-2.2	0.1	-0.7	-0.4
Comparative body size at age 10	0.1	0.4	1.1	-0.9	-1.1	-0.6	0.3	0.1	0.5	0.3	-0.6
Number of full brothers	0.7	0.9	2.5	0.1	0.4	-1.6	-1.6	-0.8	0.9	-0.7	-0.0
Worry too long after embarrassment	0.6	1.0	5.7	-2.4	-0.9	0.1	1.0	0.3	0.3	-0.1	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.2	0.9	0.2	0.6	-0.3	-1.1	-0.4	-0.3	0.5
Wheeze or whistling in the chest in last year	0.5	1.0	4.8	-1.0	-0.4	-0.2	-0.2	-0.7	-0.0	-2.2	-1.1
Number of children fathered	0.5	0.6	2.8	-0.7	-0.3	0.5	0.4	1.7	1.0	0.1	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.7	-1.1	-1.3	0.2	1.1	0.2	0.1	0.5	-0.1
Age at first live birth	1.6	2.9	5.7	1.3	-0.9	1.8	2.0	1.9	1.9	0.3	2.4
Pulse wave peak to peak time	1.5	1.8	4.5	1.8	1.2	0.9	0.9	0.9	2.1	0.1	1.6
Health satisfaction	1.8	2.4	7.5	0.8	-0.3	-1.6	-0.8	-0.4	2.5	-2.7	-1.2
Shortness of breath walking on level ground	1.1	1.3	4.9	-0.6	0.0	-0.7	-1.2	-0.8	1.6	-2.2	0.4
Qualifications: College or University degree	0.8	2.4	6.0	1.2	-1.9	0.7	1.8	2.4	1.0	1.2	1.5
Eye problems/disorders: None of the above	0.3	0.4	1.3	0.5	0.4	-0.4	-0.1	0.6	0.2	1.1	0.8
Mouth/teeth dental problems: Loose teeth	0.6	0.8	1.8	0.3	-0.7	0.3	0.5	-1.0	-0.9	-1.3	1.2
Emphysema/chronic bronchitis	0.7	0.8	2.9	0.0	1.2	-1.1	-1.7	-0.0	-0.4	-0.3	-0.8
Medication for pain relief, constipation, heartburn	0.0	0.1	0.3	0.5	-0.1	0.0	0.1	-0.1	-0.4	-0.2	0.2
Neck or shoulder pain in last month	0.4	0.5	2.5	0.7	0.2	0.3	1.6	-0.8	0.1	0.2	0.7
Medication: Blood pressure	1.0	1.8	6.3	-1.9	1.5	-1.1	-0.2	-0.8	0.4	-2.5	-0.8
Angina (self-reported)	0.4	0.5	1.2	0.5	0.9	-0.1	0.1	0.8	1.1	0.2	-1.0
Migraine (self-reported)	1.0	1.3	2.9	-1.7	-0.2	-1.1	-1.5	-1.3	-1.1	-0.9	-0.4
Medication: Ibuprofen	0.3	0.4	1.0	0.7	0.7	-0.2	0.8	-0.4	1.0	0.5	-0.4
Medication: Allopurinol	2.8	3.7	10.2	0.1	0.9	1.7	2.5	2.4	3.2	0.9	1.6
Medication: Omeprazole	0.5	0.6	1.6	-1.3	-0.3	0.8	-1.0	0.1	-0.0	-0.8	-0.8
Medication: Seretide 50 evohaler	0.4	0.4	1.4	0.7	1.0	-0.1	0.7	0.3	-0.2	1.2	-0.1
Mean time to correctly identify matches	0.9	1.7	4.1	0.2	-0.9	-1.0	-1.0	-1.9	-0.9	-2.0	-1.4
Heart disease (mother)	0.7	0.8	2.7	-1.6	-0.3	1.3	1.2	0.1	0.4	-0.6	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.8	2.9	0.1	0.7	1.2	-1.0	-0.1	0.3	1.7	0.4
Whole body fat mass	1.3	5.5	19.9	-4.5	0.8	-1.5	-1.9	1.2	-0.2	-2.8	-2.9
Leg fat mass (right)	1.2	4.8	18.7	-4.3	0.3	-1.3	-1.5	1.1	0.1	-2.6	-2.7
Arm predicted mass (right)	0.8	4.1	14.1	-3.8	-0.5	-1.1	-0.9	1.9	0.5	-2.3	-2.6
Pulse rate, automated reading	0.5	1.5	5.6	-2.4	-0.7	-0.4	-0.1	-1.9	-0.5	-1.3	0.2
Alcohol intake frequency.	0.7	1.7	4.2	-0.5	-1.3	-2.1	-1.2	-0.9	-0.1	-1.6	-1.6
Comparative height size at age 10	0.1	0.7	2.9	-0.7	0.2	-1.1	-0.1	0.9	0.5	-0.4	-1.7
Number of full sisters	0.8	1.0	2.6	-0.8	-1.6	-0.1	-1.6	-0.0	-0.0	-1.2	-0.8
Suffer from ‘nerves’	0.5	0.8	2.0	-0.6	-1.2	1.0	-0.8	-0.6	-1.4	0.4	-0.4
Overall health rating	1.0	2.2	6.8	-1.9	1.2	-0.3	-1.7	-0.1	-0.2	-2.6	-1.8
Chest pain or discomfort	0.3	0.4	1.1	-0.4	0.1	0.9	0.1	0.6	0.4	-1.0	0.8
Had major operations	0.6	0.7	3.7	-1.9	-0.6	-0.4	0.3	-0.3	-0.1	-0.9	-0.5
Age at last live birth	1.8	2.7	5.3	2.3	-0.2	1.5	1.8	1.6	1.8	0.1	2.2
Family relationship satisfaction	0.7	0.9	2.3	0.6	-0.1	-1.5	-0.7	-0.6	1.1	-1.2	-1.1
Leg pain on walking	1.6	1.9	5.5	-1.6	0.1	-1.9	-1.6	-0.8	-0.8	-0.4	-2.3
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	4.6	-0.3	2.1	0.9	1.3	1.9	0.3	1.1	0.5
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.0	0.6	1.0	0.1	0.5	-0.8	0.1	-0.2	-0.6
Illness, injury, bereavement, stress in last 2 years	2.0	2.5	5.4	2.2	0.2	1.6	2.3	1.8	0.4	1.2	1.5
Medication: Aspirin	0.8	1.1	3.0	-1.7	0.4	-1.4	-0.6	-0.4	0.3	-1.4	-1.1
Supplements: Vitamin C	0.5	0.6	1.7	0.2	-1.3	1.2	0.3	-0.9	-0.1	0.5	0.4
Knee pain experienced in last month	2.3	3.6	8.1	-2.2	0.2	-1.2	-2.2	-2.1	-1.6	-1.5	-2.9
Hypertension (Self-reported)	0.8	2.3	6.5	-2.5	-0.6	0.3	-1.6	-0.8	-1.7	-2.0	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.3	1.0	-1.1	1.1	-1.0	0.2	0.5	0.5	-0.4
Illnesses of father: Heart disease	0.4	0.6	2.5	1.1	-1.6	-0.1	-0.1	0.6	-0.5	0.3	-0.2
Illnesses of siblings: Diabetes	2.3	2.8	11.7	-2.0	0.6	-1.0	-1.9	0.2	-1.1	-0.7	-3.4
Smoking status: Previous	0.3	0.5	1.1	0.8	-0.7	-0.1	0.7	-1.0	-0.9	0.0	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	4.1	-0.7	-0.7	0.0	1.5	0.3	1.4	0.2	2.0
Whole body fat-free mass	0.8	4.4	15.1	-3.9	-1.0	-1.0	-0.5	2.1	1.1	-2.5	-2.5
Leg fat-free mass (right)	1.0	5.4	19.9	-4.5	-1.0	-1.2	-1.1	1.8	1.2	-2.9	-2.5
Arm fat percentage (left)	1.3	5.2	22.7	-4.8	0.7	-1.2	-1.9	0.9	-0.5	-2.4	-2.6
Average weekly red wine intake	2.4	3.5	10.6	0.6	0.1	1.8	2.2	3.2	-0.1	3.1	-0.0
Handedness (chirality/laterality): Left-handed	0.6	0.7	3.4	-0.1	0.1	0.4	1.0	-0.7	0.2	-1.9	-0.7
Mood swings	0.3	0.6	2.2	-1.5	0.1	0.1	-1.2	0.4	-0.5	0.6	-0.2
Loneliness, isolation	2.0	2.8	5.6	-2.1	1.0	-2.4	-1.9	-0.9	-0.4	-1.8	-1.9
Long-standing illness, disability or infirmity	0.9	1.3	3.3	-1.7	0.7	0.3	-0.4	0.8	1.8	-1.6	-0.5
Ever had bowel cancer screening	1.8	2.2	5.1	-2.2	-1.6	-1.1	-0.2	-1.8	-1.2	-1.2	-1.4
Diabetes diagnosed by doctor	1.7	2.8	8.2	-1.4	0.3	-1.9	-1.3	0.5	1.9	-2.9	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	5.6	-0.6	0.1	0.8	0.8	2.4	0.5	-0.3	0.1
Friendships satisfaction	0.4	0.5	1.7	0.6	0.5	-0.3	-0.7	1.3	0.8	-0.3	-0.7
Qualifications: nursing, teaching	0.7	1.1	2.3	-0.1	0.2	0.8	1.1	1.3	1.4	-1.5	1.1
Commuting to job workplace: Walk	0.3	0.3	0.9	-0.7	-1.0	-0.2	-0.2	-0.3	-0.3	-0.8	-0.1
Eye problems/disorders: Cataract	0.6	0.7	2.3	0.3	0.5	-1.2	-0.5	-0.7	0.4	-1.5	-1.0
Mouth/teeth dental problems: Mouth ulcers	2.3	3.6	10.2	1.2	1.0	3.0	1.7	0.9	-0.2	1.9	3.2
Medication for cholesterol	0.4	0.6	1.5	-0.3	0.6	-1.0	-0.0	-0.2	1.2	-1.2	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.6	1.9	3.4	-0.8	-1.2	-1.8	-1.6	-1.5	-1.0	-0.7	-1.8
Back pain experienced in last month	0.4	0.6	1.4	-1.0	0.5	0.1	-0.2	-0.3	-0.9	-1.2	-1.0
Mineral and other dietary supplements	1.3	1.7	5.9	2.4	1.2	1.0	1.6	1.0	1.2	0.7	0.6
Breast cancer (self-reported)	1.3	1.5	4.4	1.0	1.4	0.7	2.1	1.9	-0.2	0.5	0.5
Asthma (self-reported)	1.0	2.1	7.0	-1.3	0.3	-1.5	-0.9	-2.1	-0.5	-2.6	0.2
Osteoporosis (self-reported)	0.7	0.9	2.5	-0.5	-0.1	1.6	0.8	1.4	0.5	-0.3	1.1
Osteoarthritis (self-reported)	0.9	1.1	2.8	0.4	0.5	-0.6	-1.3	-0.6	-1.4	-1.0	-1.7
Medication: Aspirin	0.8	1.1	2.3	-1.5	0.5	-1.3	-0.3	0.1	0.9	-1.5	-1.1
Medication: Gliclazide	0.6	0.7	1.5	-0.5	0.6	-0.4	1.0	0.7	1.2	-0.3	-1.2
Illnesses of father: None of the above (group 1)	1.6	2.0	6.2	-2.0	0.8	-1.3	-1.5	-2.5	-0.8	-0.7	-0.4
Smoking status: Current	1.6	2.5	7.0	-1.0	2.1	-2.7	-0.3	-0.6	0.7	-1.6	-1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.8	3.7	8.8	1.3	-0.7	2.7	2.4	0.3	1.3	2.0	3.0
Whole body water mass	0.8	4.8	16.6	-4.1	-1.1	-1.1	-0.6	2.0	1.1	-2.7	-2.6
Leg predicted mass (right)	1.0	5.4	19.6	-4.4	-0.9	-1.3	-1.1	1.9	1.3	-2.9	-2.5
Arm fat mass (left)	1.6	6.4	28.5	-5.3	0.5	-1.3	-1.7	1.3	-0.3	-2.9	-2.8
Number of self-reported non-cancer illnesses	0.9	1.5	5.2	-2.3	-0.4	0.2	-0.8	-0.1	-1.4	-1.6	-1.4
Average weekly champagne plus white wine intake	1.8	2.5	9.5	-0.5	-0.5	1.5	3.1	1.4	0.8	0.9	2.1
Miserableness	0.7	1.2	5.9	-2.4	-0.2	0.4	-0.4	1.4	0.1	-1.3	0.4
Guilty feelings	0.1	0.2	0.6	0.3	-0.6	-0.1	-0.5	0.4	0.3	0.8	-0.0
Wears glasses or contact lenses	1.2	1.4	4.0	-1.4	-2.0	0.6	1.3	0.8	0.7	-1.2	0.4
Ever taken oral contraceptive pill	0.4	0.4	1.3	0.5	1.1	0.3	-0.1	0.6	1.0	0.3	0.3
Hearing aid user	0.3	0.3	0.9	0.4	-0.1	0.6	-0.9	0.4	0.2	0.8	-0.2
Mother’s age at death	1.6	2.0	10.1	-1.4	-0.9	-0.2	-0.9	-1.1	-3.2	-0.6	-0.8
Financial situation satisfaction	0.4	0.4	1.0	-0.2	0.8	-0.3	-1.0	-0.6	0.4	-1.0	-0.6
Tinnitus: Yes, now most or all of the time	0.8	1.0	2.3	1.3	0.7	-1.0	0.1	-1.5	-1.1	0.4	-0.9
Commuting to job workplace: Public transport	0.6	0.7	1.2	1.0	-0.9	0.3	-0.2	-0.8	-0.8	-0.9	1.1
Eye problems/disorders: Glaucoma	0.3	0.4	0.8	0.1	0.1	0.8	0.3	-0.8	-0.9	0.4	-0.8
Medication: Blood pressure	0.7	1.3	4.0	0.8	-0.8	1.8	-0.5	-0.6	-2.0	1.0	0.3
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.0	-0.4	1.0	-0.3	0.9	0.9	-0.6	-0.3	0.1
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.5	-1.3	-0.8	-0.6	-1.6	-0.1	-0.8	-0.6	-0.6
High cholesterol (Self-reported)	0.1	0.2	0.8	-0.4	0.8	0.1	-0.5	0.9	-0.2	0.1	0.1
Medication: Bendroflumethiazide	0.5	0.8	1.6	-1.1	0.7	0.1	-1.1	-0.6	-1.0	-1.3	-0.1
Medication: Paracetamol	1.1	1.6	4.5	0.8	0.2	0.4	1.7	1.6	2.1	0.6	1.3
Medication: Lisinopril	0.3	0.4	2.1	-0.3	1.5	-0.3	0.3	0.2	-0.4	0.4	0.2
Medication: Atorvastatin	0.5	0.6	1.1	0.1	0.3	-1.0	-0.9	-0.6	0.9	-0.9	-0.9
Illnesses of father: High blood pressure	2.3	2.8	5.9	0.4	-1.9	1.6	1.4	0.8	2.4	2.0	1.9
Alcohol drinker status: Never	0.8	1.0	2.5	1.6	-1.1	0.2	1.2	-0.2	0.4	1.4	0.7
Ever smoked	0.3	0.6	1.4	-0.3	1.2	-1.0	0.5	0.7	0.1	0.6	-1.0
Basal metabolic rate	0.9	5.0	18.1	-4.3	-0.8	-1.0	-0.8	2.0	1.0	-2.8	-2.6
Leg fat percentage (left)	1.1	3.8	14.8	-3.8	0.3	-1.1	-1.5	0.8	-0.6	-2.1	-2.7
Arm fat-free mass (left)	0.9	4.6	16.7	-4.1	-1.1	-1.1	-0.8	1.7	0.3	-2.6	-2.6
Number of operations (self-reported)	0.6	0.8	4.4	-2.1	-0.5	-0.6	-0.4	-0.3	0.4	-1.1	-0.6
Average weekly beer plus cider intake	0.8	1.2	7.1	-0.7	0.9	0.0	0.6	-0.3	0.9	-2.7	0.1
Irritability	0.8	1.4	3.2	-1.8	-0.0	-0.1	-1.3	-1.4	-1.3	0.5	-1.5
Risk taking	0.8	1.2	5.4	1.0	2.3	0.4	0.7	-0.7	-0.9	0.9	0.1
Ever had prostate specific antigen (PSA) test	0.3	0.4	0.8	-0.9	-0.3	0.1	0.8	-0.9	-0.1	-0.8	-0.2
Fractured/broken bones in last 5 years	0.9	1.2	3.3	-1.8	1.4	-1.2	-0.8	0.1	1.0	0.2	-1.0
Age started oral contraceptive pill	0.3	0.4	2.3	1.5	0.2	-0.2	-0.2	-0.6	-0.3	-0.2	-0.7
Diastolic blood pressure, automated reading	0.1	0.2	0.4	-0.4	0.7	0.6	-0.5	0.0	0.2	-0.3	0.3
Ever depressed for a whole week	0.9	1.1	3.3	-1.7	0.4	-1.1	-0.5	0.4	0.1	-0.8	-1.8
Unable to work because of sickness or disability	2.5	3.3	12.0	-1.6	0.8	-1.5	-1.0	-2.5	-0.2	-3.5	-1.3
Commuting to job workplace: Cycle	0.8	1.0	2.9	-0.2	1.7	-0.6	-0.7	-0.2	0.9	-1.6	-0.5
Myopia	0.4	0.6	1.0	0.8	-1.0	0.8	0.9	-0.1	-0.8	-0.8	0.7
Vascular/heart problems diagnosed by doctor	0.6	1.6	3.8	2.0	0.4	0.3	1.6	1.1	1.0	1.6	1.0
Cholesterol lowering medication	0.3	0.5	1.4	-0.9	0.5	-0.4	-0.6	-0.2	-1.0	0.1	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	2.4	-1.3	-0.6	0.7	-1.6	-0.6	-0.3	-1.1	-0.7
Pain experienced in last month	0.7	1.1	3.5	1.9	-0.1	-0.1	-0.3	0.0	1.9	0.5	1.2
Supplements: Calcium	0.4	0.4	2.4	-0.5	0.1	0.2	0.2	0.4	1.6	-0.2	0.7
Basal cell carcinoma (self-reported)	0.6	0.7	3.1	-0.9	1.8	0.2	-0.1	-0.6	-1.0	0.4	0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.8	-0.4	0.8	-0.1	-0.9	0.1	0.9	0.2	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.5	-0.7	-0.4	-0.5	-0.4	-0.2	0.3	0.7	-0.2
Heart disease (siblings)	0.9	1.1	4.1	-0.2	-1.0	-1.2	-2.0	-0.5	1.4	0.3	-0.6
Alcohol drinker status: Previous	1.6	1.8	3.8	-1.6	-0.6	-1.2	-1.1	-0.1	-1.9	-1.8	-1.4
Pack years of smoking	1.0	1.5	4.2	-1.2	2.1	-1.5	-1.1	0.1	-0.3	-0.7	-1.4
Impedance of whole body	1.0	5.0	16.4	4.0	0.9	1.1	1.3	-0.6	-0.4	3.2	3.0
Leg fat mass (left)	1.4	5.5	20.4	-4.5	0.3	-1.5	-1.8	1.0	-0.0	-2.9	-3.0
Arm predicted mass (left)	0.9	4.8	17.2	-4.2	-0.9	-1.2	-1.0	1.6	0.5	-2.8	-2.7