Best TWAS P=2.48e-10 · Best GWAS P=2.25e-13 conditioned to 3.65e-13
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Frontal Cortex BA9 | TEX29 | 0.45 | 0.10 | lasso | 8 | 0.24 | 4.2e-07 | -5.0 | -6.3 | 2.5e-10 | -0.01 | 0.12 | 0.06 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ARHGEF7 | 0.09 | 0.07 | blup | 142 | 0.08 | 3.1e-09 | -5.2 | 6.1 | 1.2e-09 | -0.04 | 0.95 | 0.05 | FALSE |