TWAS hub - ARHGEF7

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1210	0.0480	6.5e-03	0.037	NA	0.044	NA	0.029	4.1e-03	NA	1.8e-03	NA	9.8e-03
2	GTEx	Artery Tibial	0.2265	0.0566	9.3e-05	0.065	NA	0.037	NA	0.063	8.3e-06	NA	6.4e-04	NA	1.1e-05
3	GTEx	Brain Cerebellum	0.2800	0.0850	2.6e-03	0.283	NA	0.188	NA	0.269	5.3e-09	NA	3.1e-06	NA	1.4e-08
4	GTEx	Cells Transformed fibroblasts	0.1730	0.0490	2.6e-04	0.111	NA	0.088	NA	0.099	1.2e-08	NA	3.9e-07	NA	7.6e-08
5	GTEx	Colon Transverse	0.2090	0.0530	5.1e-05	0.239	NA	0.187	NA	0.229	1.1e-11	NA	3.0e-09	NA	3.1e-11
6	GTEx	Esophagus Mucosa	0.2940	0.0580	1.6e-07	0.116	NA	0.133	NA	0.158	3.8e-08	NA	3.6e-09	NA	9.6e-11
7	GTEx	Esophagus Muscularis	0.2140	0.0560	6.8e-05	0.108	NA	0.071	NA	0.092	4.3e-07	NA	3.9e-05	NA	3.2e-06
8	GTEx	Lung	0.1440	0.0464	6.7e-04	0.063	NA	0.046	NA	0.058	1.4e-05	NA	1.9e-04	NA	3.0e-05
9	GTEx	Muscle Skeletal	0.1410	0.0411	1.6e-04	0.051	NA	0.061	NA	0.043	9.7e-06	NA	1.3e-06	NA	4.7e-05
10	GTEx	Nerve Tibial	0.2724	0.0442	6.7e-11	0.222	NA	0.259	NA	0.271	1.1e-15	NA	2.0e-18	NA	2.7e-19
11	GTEx	Skin Not Sun Exposed Suprapubic	0.3050	0.0590	9.6e-08	0.224	NA	0.220	NA	0.229	1.7e-12	NA	2.8e-12	NA	9.0e-13
12	GTEx	Skin Sun Exposed Lower leg	0.2990	0.0470	1.9e-13	0.283	NA	0.287	NA	0.299	1.3e-23	NA	5.8e-24	NA	4.5e-25
13	GTEx	Testis	0.3040	0.0800	4.2e-05	0.262	NA	0.224	NA	0.247	5.1e-12	NA	2.7e-10	NA	2.4e-11
14	GTEx	Whole Blood	0.1040	0.0340	9.5e-04	0.052	NA	0.032	NA	0.035	1.5e-05	NA	5.8e-04	NA	3.2e-04
15	METSIM	Adipose	0.0827	0.0236	1.4e-06	0.077	0.048	0.058	0.059	0.069	1.4e-11	9.5e-08	3.9e-09	3.7e-09	1.4e-10
16	YFS	Blood	0.2138	0.0307	0.0e+00	0.085	0.122	0.134	0.140	0.134	2.8e-26	1.0e-37	1.1e-41	2.2e-43	1.2e-41
17	TCGA	Brain Lower Grade Glioma	0.0885	0.0283	4.9e-08	0.071	0.079	0.061	NA	0.064	1.7e-08	3.1e-09	1.9e-07	NA	9.0e-08
18	TCGA	Prostate Adenocarcinoma	0.0552	0.0242	3.0e-03	0.003	0.015	0.008	NA	0.008	1.5e-01	9.0e-03	4.9e-02	NA	3.9e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Time employed in main current job	8.0	9.2	16.4	3.4	1.8	3.5	3.2	1.5	1.4	3.9	4.0	0.7	3.6	3.4	3.7	3.6	4.0	3.4	3.4	0.6	1.3
Pulse wave reflection index	5.4	6.7	9.6	3.1	2.7	2.9	3.1	2.4	2.3	2.7	2.3	2.2	2.7	2.9	2.9	2.7	2.2	3.1	0.6	2.9	1.4
Length of working week for main job	5.1	5.6	8.2	2.9	0.8	2.6	2.5	2.6	2.4	2.4	2.3	2.8	2.7	2.7	2.7	2.7	2.4	2.5	0.0	2.5	-0.7
Heart disease (mother)	4.6	5.6	9.6	-2.5	0.1	-2.9	-3.1	-3.0	-1.6	-2.7	-1.9	-1.0	-3.1	-3.1	-2.7	-3.0	-1.9	-3.0	0.9	-1.8	1.2
Ever had bowel cancer screening	4.6	5.4	12.7	1.6	1.1	2.4	2.5	2.9	2.8	2.5	2.4	2.4	2.5	2.5	2.5	2.5	2.2	2.2	0.1	3.6	1.0
Pulse wave Arterial Stiffness index	4.2	4.9	7.8	2.2	1.8	2.5	2.8	2.5	2.1	2.3	1.8	1.5	2.3	2.6	2.5	2.4	1.8	2.6	1.1	2.7	1.3
Pulse wave peak to peak time	4.1	4.9	7.9	-2.1	-1.4	-2.5	-2.8	-2.7	-2.4	-2.3	-1.7	-1.4	-2.4	-2.6	-2.5	-2.4	-1.8	-2.6	-1.0	-2.8	-1.1
Emphysema/chronic bronchitis	3.8	4.2	15.3	1.4	0.7	2.0	2.4	3.7	3.0	1.4	0.8	1.7	1.9	2.2	1.8	1.8	0.8	2.2	-0.5	3.9	0.0
Commuting to job workplace: Cycle	3.7	4.4	6.4	-2.1	-1.2	-2.2	-2.4	-2.0	-2.5	-2.0	-2.5	-2.2	-2.3	-2.3	-2.4	-2.2	-2.5	-2.0	-1.7	-1.9	-1.2
Medication: Paracetamol	3.3	5.5	8.4	2.8	1.5	2.9	2.7	1.4	1.6	2.9	2.5	1.5	2.6	2.7	2.8	2.6	2.4	2.9	1.8	1.6	1.7
Heart attack/myocardial infarction (self-reported)	3.3	4.3	7.8	-2.0	-0.3	-2.3	-2.2	-2.1	-1.6	-2.4	-2.6	-0.8	-2.5	-2.4	-2.4	-2.5	-2.8	-2.2	-1.4	-1.8	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	3.2	6.7	9.8	2.9	1.8	2.9	2.8	1.6	2.8	3.1	3.0	1.4	2.9	2.8	2.8	2.8	2.8	2.9	2.2	1.3	2.2
Fasting Glucose	3.1	3.7	13.5	2.0	0.8	1.4	1.7	3.7	3.2	1.1	1.1	3.1	1.4	1.6	1.4	1.4	1.3	1.5	1.4	2.7	0.6
Commuting to job workplace: Car/motor vehicle	3.1	3.6	14.5	1.6	1.3	1.9	2.1	1.3	2.2	1.9	1.7	3.8	1.9	2.0	2.0	1.8	1.4	1.7	0.3	2.1	-0.3
Myopia	3.1	4.5	9.9	1.8	1.6	2.1	2.1	2.3	3.1	2.1	2.4	2.0	2.1	2.2	2.1	2.3	2.6	2.0	1.2	2.3	0.7
BMI	3.0	17.4	53.1	3.8	1.6	3.8	4.2	5.9	5.1	3.2	3.5	6.2	3.8	4.1	3.9	4.0	3.6	3.9	0.7	7.3	0.0
Deep venous thrombosis (DVT) (self-reported)	3.0	3.8	6.4	1.9	2.4	2.0	1.8	1.8	1.8	1.8	2.3	1.7	1.8	2.0	2.2	1.9	2.0	1.9	1.2	2.5	1.9
Number of treatments/medications taken	2.9	5.1	7.2	2.4	2.2	2.6	2.7	1.7	2.0	2.4	2.0	2.5	2.3	2.5	2.5	2.3	1.9	2.7	2.2	2.3	1.1
Heart attack	2.9	3.6	7.0	-1.9	-0.3	-2.1	-2.0	-1.6	-1.3	-2.3	-2.5	-0.8	-2.3	-2.2	-2.3	-2.3	-2.7	-2.0	-1.2	-1.6	-1.1
Loud music exposure frequency	2.9	3.2	5.8	1.9	0.6	2.2	2.1	1.4	0.7	2.2	2.0	0.4	2.4	2.3	2.3	2.2	2.0	2.2	0.4	1.0	-1.1
Asthma	2.7	5.4	10.0	-2.1	-0.8	-2.5	-2.6	-3.1	-3.2	-2.7	-1.8	-1.6	-2.5	-2.6	-2.3	-2.5	-2.2	-2.7	-2.5	-1.6	-1.6
Blood clot in the leg (DVT)	2.7	3.5	6.1	2.0	2.0	1.9	1.7	1.8	1.7	1.8	2.2	1.5	1.8	1.9	2.1	1.9	2.0	1.8	0.9	2.5	1.5
Medication for pain relief, constipation, heartburn	2.7	4.6	11.5	-2.3	-2.5	-2.4	-2.3	-0.5	-1.3	-2.2	-2.1	-1.3	-2.0	-2.2	-2.4	-2.1	-2.1	-2.4	-3.4	-0.5	-2.4
Commuting to job workplace: Walk	2.7	2.9	7.7	-2.0	-0.8	-1.8	-1.9	-1.3	-2.0	-1.8	-1.5	-2.8	-1.9	-1.9	-1.7	-1.8	-1.6	-1.9	-0.1	-1.2	0.6
Leg fat mass (left)	2.7	10.4	38.2	3.0	1.3	2.7	3.0	4.2	4.1	2.2	2.7	5.1	2.9	3.0	2.9	2.8	2.7	2.7	-0.0	6.2	-0.7
Cardiovascular Disease	2.6	8.5	11.7	3.2	2.8	3.2	3.3	2.3	3.3	3.0	2.9	3.3	2.9	3.1	3.1	3.1	2.8	3.1	1.2	3.4	1.7
Leg fat mass (right)	2.6	10.2	40.5	2.9	1.3	2.6	2.9	4.2	3.9	2.1	2.6	5.2	2.7	2.9	2.8	2.7	2.6	2.7	-0.3	6.4	-0.8
Number of self-reported non-cancer illnesses	2.6	4.4	9.1	2.1	2.5	2.3	2.5	1.5	2.2	1.9	1.9	3.0	2.0	2.2	2.2	2.0	1.7	2.2	0.8	2.7	1.3
Number of children fathered	2.5	2.9	7.3	2.2	0.9	2.0	1.8	0.2	-0.2	2.0	2.7	0.4	2.2	1.9	2.1	2.1	2.5	1.8	-0.2	0.4	-0.5
Type 2 Diabetes (T2D) (2012)	2.4	2.8	4.9	1.9	2.2	2.0	1.9	0.3	0.7	1.7	1.9	1.0	1.8	1.9	2.0	2.2	1.7	2.1	1.1	1.2	0.8
Multivitamins +/- minerals	2.4	3.0	4.9	2.1	1.1	2.0	2.2	1.8	1.5	1.7	1.6	1.8	1.8	1.9	1.8	2.0	1.8	2.0	0.9	1.5	0.7
Body mass index (BMI)	2.4	10.3	37.0	2.9	1.4	2.7	3.0	4.4	4.1	2.2	2.6	5.0	2.8	3.0	2.8	2.8	2.7	2.8	0.1	6.1	-0.2
Asthma (self-reported)	2.4	4.7	9.0	-2.0	-0.6	-2.3	-2.4	-2.9	-3.0	-2.5	-1.7	-1.6	-2.3	-2.4	-2.0	-2.3	-2.1	-2.5	-2.2	-1.6	-1.3
Primary Biliary Cirrhosis	2.3	3.3	5.3	-2.1	-2.0	-2.1	-2.0	-0.8	-1.6	-2.2	-2.0	-0.0	-1.9	-2.0	-2.3	-1.9	-1.8	-2.0	-1.9	-0.9	-1.6
Whole body fat mass	2.3	9.5	36.5	3.0	1.4	2.6	2.8	4.0	3.7	2.1	2.6	4.9	2.7	2.9	2.8	2.7	2.6	2.6	-0.2	6.0	-0.7
Leg fat percentage (left)	2.3	8.5	30.1	2.9	1.7	2.5	2.6	3.4	3.7	2.2	2.8	4.2	2.6	2.7	2.8	2.6	2.7	2.5	0.4	5.5	0.0
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.4	9.3	1.8	0.9	1.8	2.0	2.4	2.8	1.5	1.2	2.2	1.7	2.0	1.8	1.8	1.1	1.8	0.9	3.1	0.2
Leg fat percentage (right)	2.2	8.1	32.9	2.8	1.7	2.4	2.5	3.3	3.5	2.0	2.6	4.4	2.4	2.6	2.6	2.4	2.6	2.4	-0.0	5.7	-0.1
Arm fat mass (left)	2.2	8.9	34.7	2.7	1.1	2.4	2.7	4.1	3.7	1.9	2.4	4.8	2.6	2.8	2.6	2.6	2.4	2.5	-0.5	5.9	-0.9
Medication: Blood pressure	2.2	4.1	6.1	2.3	1.4	2.4	2.4	1.5	1.8	2.1	2.2	1.8	2.3	2.4	2.4	2.5	2.0	2.3	0.9	2.2	0.3
Qualifications: A levels/AS levels or equivalent	2.1	4.8	9.3	-2.8	-1.0	-2.9	-2.8	-1.6	-1.2	-2.4	-1.9	-0.3	-2.8	-2.8	-2.8	-2.8	-1.7	-3.0	-0.9	-1.3	-0.2
Arm fat percentage (left)	2.1	8.2	29.3	2.9	0.7	2.6	2.7	3.7	3.2	2.1	2.6	3.7	2.7	2.9	2.7	2.8	2.8	2.6	-0.3	5.4	-0.9
Medication: Metformin	2.0	2.9	5.4	2.3	2.2	1.9	1.7	0.8	1.0	1.4	2.0	1.7	1.8	1.8	2.0	1.7	1.8	1.9	0.4	2.0	-0.2
Waist circumference	2.0	7.2	28.2	2.8	1.0	2.1	2.4	3.7	3.3	1.7	2.0	4.5	2.2	2.4	2.3	2.2	2.0	2.2	-0.4	5.3	-0.7
Hip circumference	2.0	8.5	32.7	2.7	1.8	2.5	2.8	3.7	3.6	2.0	2.2	4.6	2.5	2.8	2.6	2.5	2.1	2.6	-0.4	5.7	-0.1
Glaucoma (self-reported)	2.0	2.4	4.9	-1.2	-2.0	-1.6	-1.7	-0.8	-0.5	-1.6	-1.6	-0.7	-1.4	-1.6	-1.7	-1.6	-1.6	-1.5	-2.0	-1.2	-2.2
Body fat percentage	2.0	7.8	30.1	2.8	1.4	2.4	2.6	3.4	3.3	2.0	2.5	4.0	2.5	2.7	2.6	2.5	2.6	2.4	0.2	5.5	-0.4
High cholesterol (Self-reported)	2.0	3.6	8.8	1.7	1.4	1.7	2.1	2.7	3.0	1.8	1.1	2.7	1.7	1.9	1.7	1.7	1.4	1.9	1.3	2.3	-0.0
Type 2 Diabetes (T2D) (2018)	1.9	3.6	6.9	2.2	1.2	2.0	2.0	2.2	1.7	1.6	2.0	2.4	2.0	2.0	2.1	1.8	1.9	1.9	0.0	2.6	-0.8
Medication for cholesterol	1.9	3.0	5.1	-2.3	-1.2	-2.0	-2.0	-1.5	-1.1	-2.1	-1.7	-1.6	-1.9	-2.0	-1.9	-2.1	-1.6	-2.0	-0.7	-1.5	0.2
Depression (Nagel 2018)	1.8	2.7	9.9	1.0	0.9	1.3	1.7	2.2	2.5	1.2	0.7	3.1	1.2	1.4	1.3	1.3	0.7	1.3	1.7	2.8	0.8
Age at First Birth	1.8	2.6	4.2	-1.7	-0.8	-1.9	-1.8	-0.3	-1.7	-1.8	-1.9	-1.3	-2.0	-1.9	-2.0	-2.0	-1.7	-1.8	0.0	-1.5	-0.4
Trunk fat mass	1.8	7.8	29.7	2.8	1.3	2.4	2.6	3.6	3.2	1.9	2.4	4.2	2.5	2.6	2.5	2.5	2.4	2.4	-0.1	5.5	-0.8
Arm fat percentage (right)	1.8	7.1	26.2	2.7	0.7	2.4	2.5	3.3	3.0	2.0	2.4	3.6	2.5	2.6	2.5	2.5	2.5	2.4	-0.4	5.1	-0.7
Forced expiratory volume in 1-second (FEV1)	1.8	6.1	9.5	3.1	0.9	2.7	2.7	2.8	2.7	2.7	2.5	3.0	2.9	2.7	2.6	2.8	2.4	2.6	0.9	1.8	-0.4
Ever taken oral contraceptive pill	1.8	2.0	7.4	0.7	1.1	1.0	1.2	2.0	1.8	0.8	1.1	2.7	0.8	1.1	0.9	1.1	1.3	1.1	0.7	2.4	1.5
Tinnitus: Yes, now most or all of the time	1.8	2.0	3.8	-1.6	0.2	-1.8	-1.9	-1.6	-1.5	-1.7	-0.9	-0.3	-1.8	-1.7	-1.8	-1.8	-1.0	-1.9	-0.8	-1.1	-0.2
Ever had prostate specific antigen (PSA) test	1.8	2.1	5.8	0.3	0.2	1.4	1.7	2.0	2.4	1.2	1.6	0.5	1.5	1.5	1.5	1.5	1.9	1.2	1.3	1.6	1.2
Diastolic blood pressure, automated reading	1.8	5.7	11.1	2.2	0.2	2.3	2.4	2.7	2.0	2.2	2.7	3.3	2.6	2.5	2.4	2.7	2.8	2.2	0.1	3.2	-1.4
Smoking Status	1.7	4.0	7.2	2.7	-0.6	2.2	2.1	2.3	0.7	2.3	1.8	-0.2	2.4	2.3	2.2	2.3	2.0	2.3	-1.6	1.8	-2.2
Weight	1.7	8.5	33.8	2.6	1.5	2.3	2.6	4.1	3.5	1.7	2.3	5.0	2.4	2.6	2.4	2.4	2.2	2.3	-0.4	5.8	-0.9
Arm fat mass (right)	1.7	7.0	29.4	2.3	0.7	2.1	2.3	3.7	3.3	1.6	2.0	4.5	2.2	2.4	2.2	2.2	2.1	2.1	-0.6	5.4	-0.9
Trunk fat percentage	1.6	6.3	24.5	2.6	1.3	2.2	2.4	3.0	2.8	1.7	2.2	3.7	2.2	2.4	2.4	2.2	2.3	2.2	0.0	5.0	-0.6
Chronic bronchitis/emphysema (father)	1.6	1.9	3.6	1.4	0.9	1.6	1.7	1.0	1.5	1.4	1.3	1.9	1.5	1.5	1.6	1.5	1.4	1.5	0.8	1.4	0.6
Schizophrenia vs Biploar Disorder	1.5	2.0	6.8	1.1	0.4	1.4	1.4	2.3	1.5	0.9	1.3	1.1	1.4	1.4	1.3	1.5	1.2	1.3	-0.5	2.6	0.3
Major Depression (MDD)	1.5	1.9	8.3	1.0	0.4	1.2	1.6	2.3	1.7	1.0	0.5	1.7	1.0	1.2	1.2	1.2	0.5	1.3	0.6	2.9	0.3
Taking other prescription medications	1.5	2.3	5.8	1.6	0.2	1.7	1.6	1.5	1.1	1.4	1.4	2.3	1.6	1.6	1.5	1.6	1.3	1.6	-0.6	2.4	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.7	6.7	2.5	2.2	2.4	2.2	1.9	2.3	2.4	2.4	2.6	2.4	2.3	2.2	2.3	2.2	2.3	1.8	1.2	0.7
Age at first live birth	1.5	2.7	4.9	-1.7	-1.6	-1.6	-1.8	-2.0	-2.2	-1.4	-1.2	-1.5	-1.7	-1.8	-1.9	-1.5	-1.1	-1.7	-1.5	-2.0	-0.0
Health satisfaction	1.5	2.0	6.0	1.3	0.3	1.5	1.5	1.4	2.2	1.2	1.0	1.9	1.6	1.5	1.5	1.2	0.7	1.4	0.1	2.4	-0.1
Neck or shoulder pain in last month	1.5	2.1	4.0	1.4	1.2	1.7	1.6	1.7	1.0	1.7	1.4	0.3	1.6	1.7	1.7	1.5	1.2	1.7	-0.0	2.0	0.9
Migraine (self-reported)	1.5	1.8	3.1	0.7	0.9	1.5	1.6	1.2	0.8	1.7	1.7	0.3	1.5	1.5	1.5	1.4	1.7	1.4	0.6	1.5	1.8
Diabetes diagnosed by doctor	1.5	2.5	4.4	2.1	2.0	1.8	1.6	0.9	1.0	1.4	1.9	1.4	1.7	1.7	1.8	1.7	1.8	1.8	0.2	1.8	-0.7
Osteoporosis (self-reported)	1.5	1.9	3.1	1.5	1.1	1.6	1.4	0.1	0.1	1.6	1.3	-1.4	1.5	1.5	1.5	1.6	1.3	1.7	1.8	0.4	1.7
High blood pressure (mother)	1.4	1.9	5.0	1.9	-0.4	1.5	1.3	0.8	0.0	1.5	2.0	-0.3	1.8	1.6	1.8	1.8	2.2	1.3	0.7	0.3	-0.8
Diabetes (self-reported)	1.4	2.1	4.8	2.0	2.2	1.6	1.3	0.2	0.5	1.4	2.1	0.9	1.5	1.5	1.7	1.4	1.9	1.6	1.2	0.9	0.0
Medication: Omeprazole	1.4	1.7	3.2	1.5	1.0	1.6	1.4	0.8	0.4	1.5	1.6	0.2	1.5	1.5	1.8	1.5	1.4	1.4	0.5	0.9	1.5
Alzheimer’s Disease (in mother)	1.3	1.6	3.1	-1.2	0.2	-1.2	-1.4	-1.6	-1.3	-1.3	-1.0	-1.8	-1.4	-1.5	-1.2	-1.4	-1.2	-1.2	-0.6	-1.3	0.8
Mean Putamen Volume	1.3	1.5	4.2	1.4	0.9	1.2	1.3	1.6	2.1	0.9	0.7	1.1	1.1	1.2	1.3	1.1	0.6	1.2	0.7	1.9	0.1
Medication: Simvastatin	1.3	1.9	5.8	1.3	1.7	1.2	1.3	1.9	1.4	1.4	1.2	2.4	1.1	1.2	1.0	1.2	1.1	1.3	0.8	1.7	-0.4
Prospective memory result	1.3	1.6	3.4	-1.1	-1.5	-1.4	-1.2	-0.4	-1.3	-1.5	-1.9	-0.3	-1.4	-1.3	-1.6	-1.3	-1.7	-1.2	-0.8	-0.3	-1.5
Wheeze or whistling in the chest in last year	1.3	2.3	12.2	0.9	-0.9	0.8	0.9	2.5	1.1	0.2	0.3	1.3	0.9	0.9	0.7	0.9	0.0	0.7	-3.5	3.5	-1.6
Mouth/teeth dental problems: Loose teeth	1.3	1.5	5.9	-0.7	-2.1	-1.2	-0.9	-0.2	-0.3	-1.4	-1.5	-0.4	-1.1	-1.1	-1.3	-1.1	-1.2	-1.1	-1.4	-0.4	-2.4
Ever depressed for a whole week	1.3	1.6	8.5	0.8	-0.1	1.0	1.3	1.9	1.7	0.6	0.9	0.7	0.9	1.1	1.0	1.2	1.5	1.0	0.3	2.9	1.0
Reaction Time	1.2	2.2	14.6	0.3	-0.1	-0.3	-0.5	-3.1	-2.4	-0.2	-1.0	-2.4	-0.4	-0.6	-0.4	-0.5	-1.1	0.2	0.7	-3.8	0.2
Average weekly spirits intake	1.2	1.5	6.8	1.4	-0.6	1.1	1.4	2.1	1.3	0.7	0.4	0.2	1.3	1.3	1.1	1.1	0.6	1.1	0.2	0.8	-2.6
Ever used hormone-replacement therapy (HRT)	1.2	1.5	3.7	-1.2	-1.9	-1.3	-1.0	0.8	0.3	-1.4	-1.9	-0.6	-1.3	-1.1	-1.3	-1.3	-1.6	-1.2	-0.3	0.2	-1.2
Leg fat-free mass (left)	1.2	6.3	18.3	2.4	1.0	2.2	2.5	3.8	2.6	1.7	2.0	4.3	2.3	2.4	2.2	2.3	1.9	2.2	-0.5	4.3	-1.3
Past tobacco smoking	1.2	2.2	6.1	-1.7	1.1	-1.5	-1.4	-1.7	-0.5	-1.5	-1.1	0.2	-1.8	-1.7	-1.4	-1.5	-1.1	-1.5	1.7	-1.5	2.5
Forced vital capacity (FVC)	1.2	4.7	7.5	2.6	1.2	2.4	2.3	2.7	2.2	2.4	2.2	2.6	2.5	2.4	2.3	2.5	2.0	2.3	1.0	1.4	-0.3
Financial difficulties in last 2 years	1.2	1.6	8.4	-0.1	-1.0	-1.1	-0.8	0.9	0.1	-1.1	-1.0	0.6	-1.0	-0.9	-1.1	-1.0	-1.1	-1.0	-2.9	1.4	-2.4
Medication: Ibuprofen	1.2	1.5	3.2	1.5	1.7	1.3	1.3	-0.0	0.3	1.3	1.3	1.8	1.0	1.2	1.4	1.1	1.1	1.3	1.5	0.4	0.7
Overall health rating	1.2	2.7	7.5	1.9	1.1	1.7	1.8	1.8	2.0	1.3	1.1	2.2	1.6	1.7	1.6	1.5	0.8	1.8	0.3	2.7	-0.7
Long-standing illness, disability or infirmity	1.2	1.9	5.5	0.9	0.7	1.2	1.4	1.8	2.0	1.1	1.1	2.3	1.1	1.3	1.2	1.0	0.9	1.0	0.9	2.3	0.0
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	4.9	1.0	1.6	1.2	1.3	1.1	1.3	1.0	0.8	1.7	0.9	1.1	1.0	0.8	0.4	1.1	0.4	2.2	1.4
Systolic blood pressure, automated reading	1.1	3.3	8.3	1.7	0.1	1.7	1.9	1.9	1.6	1.8	1.9	2.9	1.8	1.8	1.8	1.9	1.9	1.7	0.3	2.8	-0.5
Impedance of leg (left)	1.1	5.2	10.3	-2.0	-0.5	-2.4	-2.6	-3.2	-2.4	-2.1	-2.2	-2.4	-2.5	-2.6	-2.3	-2.6	-2.3	-2.5	-0.8	-2.9	-0.1
Leg predicted mass (left)	1.1	6.0	18.2	2.2	1.0	2.1	2.4	3.7	2.6	1.6	1.9	4.2	2.2	2.4	2.1	2.2	1.8	2.1	-0.5	4.3	-1.2
Allergy	1.1	2.6	4.1	1.5	-0.5	1.8	1.9	1.9	1.4	1.9	1.6	-0.6	2.0	1.9	1.8	1.9	1.8	1.7	2.0	0.5	0.4
Exposure to tobacco smoke at home	1.1	1.3	2.4	-1.0	-0.7	-1.1	-1.0	-0.9	-1.6	-1.2	-1.3	-0.8	-1.0	-1.1	-1.1	-1.2	-1.4	-1.1	-1.0	-1.3	-1.1
Birth weight	1.1	2.5	4.9	1.2	0.8	1.5	1.7	2.2	2.2	1.5	1.6	2.1	1.6	1.6	1.4	1.5	1.5	1.4	0.9	2.1	-0.1
Arm predicted mass (right)	1.1	5.5	22.2	1.8	1.2	1.8	2.1	3.5	3.1	1.3	1.4	4.7	1.8	2.0	1.7	1.7	1.2	1.7	-0.5	4.4	-0.6
Supplements: Vitamin C	1.1	1.2	3.0	1.4	0.4	1.1	1.0	1.1	1.7	1.1	1.2	1.5	1.2	1.1	1.1	1.0	1.2	1.1	0.6	1.1	-0.0
Hypertension (Self-reported)	1.1	2.9	4.4	2.1	1.9	1.9	2.0	0.9	2.0	1.5	1.7	1.8	1.7	1.8	1.9	1.8	1.5	1.9	1.3	1.7	0.9
Smoking status: Current	1.1	1.8	5.0	1.4	0.3	1.4	1.6	2.2	1.2	1.2	0.7	0.5	1.4	1.6	1.4	1.6	0.8	1.5	-0.5	1.9	-1.2
Basal metabolic rate	1.1	6.2	21.7	2.2	1.1	2.1	2.3	3.7	3.0	1.6	1.7	4.7	2.1	2.3	2.0	2.1	1.6	2.0	-0.7	4.5	-1.0
Vascular/heart problems diagnosed by doctor	1.1	2.9	5.2	-2.3	-2.3	-1.9	-1.9	-0.7	-1.7	-1.6	-1.7	-1.7	-1.7	-1.7	-1.8	-1.8	-1.7	-1.9	-0.8	-1.8	-0.6
Impedance of whole body	1.1	5.4	11.9	-1.9	-0.4	-2.2	-2.5	-3.4	-3.2	-2.0	-1.9	-3.4	-2.4	-2.4	-2.1	-2.3	-1.9	-2.2	-0.4	-3.3	-0.2
Frequency of depressed mood in last 2 weeks	1.0	1.4	9.0	0.6	0.6	0.5	0.8	1.5	2.1	0.4	0.1	3.0	0.4	0.6	0.5	0.5	0.1	0.5	1.2	2.3	-0.3
Current tobacco smoking	1.0	1.6	5.3	1.2	0.0	1.3	1.4	2.3	1.1	1.1	0.6	0.7	1.3	1.4	1.2	1.5	0.8	1.3	-0.4	1.8	-1.2
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	4.3	0.8	0.2	0.9	1.1	1.8	1.4	0.5	0.8	1.3	0.8	1.1	1.0	1.0	1.1	0.9	0.1	2.1	0.5
Impedance of arm (right)	1.0	4.5	15.6	-1.6	-0.8	-1.7	-2.1	-3.1	-3.4	-1.5	-1.4	-4.0	-1.9	-1.9	-1.7	-1.7	-1.3	-1.7	-0.5	-3.4	-0.3
Falls in the last year	1.0	1.4	6.3	1.5	-0.5	0.6	0.6	1.6	0.8	0.4	0.2	0.8	0.7	0.7	0.5	0.5	0.1	0.6	-2.5	2.5	-1.8
Arm fat-free mass (right)	1.0	5.3	21.5	1.7	1.2	1.8	2.0	3.4	3.0	1.3	1.4	4.6	1.8	2.0	1.7	1.7	1.2	1.7	-0.7	4.4	-0.6
Mean time to correctly identify matches	1.0	1.9	10.4	0.8	0.1	0.5	0.2	-2.7	-2.0	0.9	-0.1	-2.4	0.3	0.1	0.4	0.2	-0.1	0.9	1.4	-3.2	1.1
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	9.9	0.4	1.1	0.7	0.6	-0.4	0.3	0.6	0.3	-0.4	0.6	0.6	0.8	0.8	0.5	0.8	3.1	-1.3	2.1
Knee pain experienced in last month	1.0	1.6	5.1	1.4	0.7	1.2	1.3	1.1	0.2	1.0	0.9	2.3	1.2	1.3	1.3	1.2	0.6	1.2	-0.5	2.2	-1.1
Leg fat-free mass (right)	1.0	5.4	14.7	2.3	0.9	2.1	2.3	3.6	2.5	1.6	1.8	3.8	2.2	2.3	2.0	2.2	1.7	2.1	-0.4	3.8	-1.2
Leg predicted mass (right)	1.0	5.3	14.8	2.2	0.8	2.1	2.3	3.6	2.5	1.6	1.7	3.8	2.1	2.3	2.0	2.2	1.6	2.1	-0.4	3.8	-1.3
Eye problems/disorders: Glaucoma	1.0	1.2	5.5	-0.1	-2.3	-0.8	-0.9	-0.7	-0.2	-0.8	-1.0	-0.3	-0.5	-0.8	-0.8	-0.9	-0.9	-0.8	-1.6	-0.6	-2.3
Pain experienced in last month	1.0	1.7	4.5	-1.2	-1.5	-1.5	-1.3	-0.9	-0.2	-1.0	-1.4	-2.0	-1.3	-1.4	-1.5	-1.2	-1.0	-1.4	0.0	-2.1	0.1
Body Mass Index (BMI) (2010)	0.9	1.2	2.8	1.0	0.3	1.1	1.1	0.8	0.7	0.7	1.5	1.6	1.2	1.2	1.2	1.3	1.4	1.0	-0.4	1.7	-0.1
Systolic Blood Pressure	0.9	4.5	7.9	2.5	0.7	2.3	2.2	1.7	1.9	2.4	2.6	2.8	2.3	2.3	2.4	2.4	2.4	2.2	1.0	2.0	0.3
Lung FEV1/FVC ratio	0.9	4.7	8.5	2.9	0.3	2.5	2.5	2.0	1.8	2.4	1.9	2.3	2.5	2.6	2.4	2.7	2.1	2.7	0.7	2.0	-0.3
Vitamin and mineral supplements	0.9	1.3	2.7	-1.0	-0.3	-1.1	-1.3	-1.4	-1.7	-1.2	-1.0	-1.1	-1.1	-1.1	-1.1	-1.1	-1.2	-1.1	-1.3	-1.0	-0.6
Medication: Co-codamol	0.9	1.1	3.3	1.0	0.3	1.3	0.7	0.0	-0.7	1.3	1.8	-0.4	1.3	1.0	1.4	1.2	1.5	0.9	0.9	-0.1	0.5
Pack years adult smoking proportion	0.9	1.4	4.3	1.5	0.5	1.0	1.1	2.1	1.6	1.3	0.5	1.4	0.9	1.1	1.0	1.0	0.8	1.3	1.3	1.2	0.2
Impedance of leg (right)	0.9	4.5	10.2	-1.9	-0.2	-2.2	-2.5	-3.2	-2.4	-1.9	-1.9	-2.1	-2.3	-2.4	-2.1	-2.4	-2.1	-2.3	-0.9	-2.6	0.0
High blood pressure	0.9	2.6	4.4	2.1	1.7	1.9	1.9	0.9	1.7	1.5	1.7	1.2	1.7	1.8	1.8	1.8	1.6	1.9	0.9	1.6	0.5
Alcohol usually taken with meals	0.9	1.5	4.6	-0.9	-1.3	-1.1	-1.0	-1.5	-1.8	-1.1	-1.0	-0.9	-0.9	-1.1	-1.0	-1.1	-1.1	-1.2	-2.1	-1.2	-1.2
Whole body fat-free mass	0.9	5.0	17.7	1.9	1.1	1.9	2.1	3.5	2.6	1.5	1.5	4.2	1.9	2.1	1.8	1.9	1.3	1.9	-0.7	4.0	-0.9
Arm fat-free mass (left)	0.9	4.8	22.5	1.6	1.3	1.5	1.7	3.3	2.9	1.1	1.2	4.7	1.5	1.6	1.5	1.4	1.0	1.4	-1.0	4.4	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	2.1	1.0	0.8	1.3	1.2	0.5	0.3	1.2	1.4	0.1	1.3	1.2	1.5	1.2	1.3	1.1	0.8	0.5	1.1
Arm predicted mass (left)	0.9	4.5	20.5	1.5	1.1	1.5	1.8	3.2	3.0	1.1	1.1	4.5	1.5	1.7	1.5	1.4	0.9	1.4	-0.5	4.2	-0.4
Coronary Artery Disease (CAD)	0.8	1.0	4.3	-1.1	-0.2	-0.9	-0.7	-0.6	-0.4	-1.5	-0.9	1.7	-0.8	-0.8	-0.8	-0.9	-1.0	-1.0	-2.1	0.1	-0.2
Angina	0.8	1.0	5.2	-0.4	1.7	-0.2	-0.1	0.7	1.8	-0.4	-0.2	2.3	-0.5	-0.3	-0.4	-0.7	-0.5	-0.4	-0.4	1.7	1.4
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.7	1.1	1.6	1.0	0.9	-0.1	0.2	0.9	1.1	1.5	0.8	0.9	1.1	0.8	1.0	0.9	1.4	0.1	0.7
Peak expiratory flow (PEF)	0.8	2.0	5.3	1.3	-0.3	1.4	1.6	1.8	2.3	1.3	1.2	1.6	1.6	1.6	1.4	1.6	1.2	1.3	1.0	1.0	0.0
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	2.3	-1.4	0.3	-1.3	-1.4	-0.8	-0.5	-1.3	-1.1	-0.1	-1.4	-1.3	-1.4	-1.4	-1.0	-1.5	0.3	-1.5	-0.5
Forced vital capacity (FVC), Best measure	0.8	3.0	4.1	1.9	2.0	2.0	1.7	1.5	1.9	2.0	1.9	2.0	1.9	1.9	1.8	1.8	1.6	1.8	1.5	0.5	0.6
Angina (self-reported)	0.8	1.1	4.8	-0.2	1.9	-0.1	0.1	0.7	1.8	-0.3	-0.0	2.2	-0.4	-0.1	-0.2	-0.5	-0.4	-0.2	-0.4	1.9	1.5
Leg pain on walking	0.8	1.1	6.5	0.8	1.1	0.2	0.1	0.8	1.2	0.0	0.8	2.2	0.2	0.3	0.4	-0.1	0.4	0.1	-1.6	2.5	-0.3
Smoking status: Previous	0.8	1.1	2.2	1.3	-1.1	1.1	1.0	0.9	0.1	1.3	1.0	-0.2	1.3	1.2	1.1	1.1	0.9	1.2	-1.2	0.7	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	3.6	0.5	0.8	0.8	0.8	1.4	0.7	0.6	0.9	1.5	0.7	0.8	0.6	0.8	0.9	0.7	-1.0	1.9	-0.1
Medication: Gliclazide	0.8	0.9	6.6	1.0	1.1	0.4	0.4	0.5	0.9	0.2	0.5	2.6	0.4	0.4	0.7	0.3	0.2	0.4	-1.0	1.7	-0.1
Whole body water mass	0.8	4.8	17.1	1.8	0.9	1.8	2.0	3.4	2.6	1.4	1.4	4.1	1.9	2.0	1.7	1.8	1.2	1.8	-0.7	3.9	-0.9
Financial situation satisfaction	0.8	0.9	4.3	0.2	-1.3	0.3	0.5	2.1	1.2	0.0	-0.3	0.4	0.4	0.5	0.3	0.5	-0.0	0.5	-1.0	1.7	-2.0
Medication: Paracetamol	0.8	1.2	2.5	1.6	0.6	1.3	1.0	0.0	-0.1	1.3	1.4	0.5	1.1	1.1	1.3	1.1	1.4	1.4	1.5	0.1	0.9
Medication: Lisinopril	0.8	1.0	3.3	-0.3	-0.9	-0.8	-0.9	-1.2	-1.8	-0.8	-1.1	0.0	-0.9	-0.9	-0.9	-1.0	-1.4	-0.7	-0.3	-1.3	-1.2
Hearing difficulty/problems with background noise	0.7	1.1	2.8	-1.4	-0.4	-1.0	-1.2	-0.8	-0.5	-0.9	-1.1	-1.5	-1.1	-1.0	-1.0	-1.1	-1.3	-1.0	-1.7	0.2	0.6
Father’s age at death	0.7	0.9	3.3	0.7	-1.8	0.8	1.0	1.6	0.6	0.7	0.6	0.4	1.1	0.9	0.7	0.9	0.8	0.7	-0.5	0.0	-1.6
Worrier / anxious feelings	0.7	1.4	4.8	1.2	-0.2	1.1	1.3	1.2	0.9	1.1	0.8	2.2	1.3	1.2	1.1	1.1	0.8	1.1	-0.7	1.5	-1.2
Medication: Amlodipine	0.7	0.9	2.5	1.1	0.6	1.2	1.2	0.0	0.4	1.1	0.8	-0.3	1.1	1.1	1.1	1.2	0.9	1.3	1.6	-0.3	0.6
Shortness of breath walking on level ground	0.7	0.9	4.6	0.2	-1.3	0.6	0.7	0.9	0.5	0.2	0.4	-0.1	0.8	0.7	0.4	0.7	0.4	0.5	-1.5	1.5	-2.1
Alcohol intake frequency.	0.7	1.7	6.7	0.3	2.6	1.0	0.9	0.4	1.2	0.6	1.1	2.0	0.6	0.8	0.8	0.8	1.0	0.9	2.5	0.6	2.1
Average weekly red wine intake	0.7	1.0	1.8	-0.7	0.6	-1.0	-1.4	-1.1	-1.1	-0.7	-0.6	-1.0	-1.2	-1.2	-1.0	-1.1	-0.8	-1.0	-0.9	-0.6	1.1
Mineral and other dietary supplements	0.7	1.0	2.3	-1.2	-0.1	-1.1	-1.1	-0.9	-1.5	-1.3	-0.7	-1.1	-1.1	-1.2	-1.1	-1.1	-0.6	-1.0	-0.6	-0.8	-0.6
Medication: Aspirin	0.7	0.9	6.5	0.9	2.5	0.6	0.6	-0.6	-0.0	0.4	0.6	0.5	0.3	0.4	0.3	0.4	0.7	0.8	1.7	0.1	1.4
Ever smoked	0.7	1.3	9.0	1.0	-0.9	0.7	0.6	1.2	-0.1	0.7	0.4	-0.5	0.9	0.9	0.6	0.7	0.5	0.6	-2.2	1.1	-3.0
Cholesterol lowering medication	0.7	1.1	2.8	1.2	1.7	1.1	1.0	0.7	0.6	1.2	1.2	1.2	1.1	1.1	1.0	1.1	0.9	1.0	0.4	1.1	-0.3
HbA1C	0.6	0.6	4.1	0.5	1.6	0.3	0.5	0.7	0.3	-0.0	0.2	2.0	0.3	0.4	0.3	0.7	0.3	0.6	0.2	1.2	0.8
Lung FVC	0.6	3.2	5.4	2.0	0.7	2.0	1.9	2.0	2.2	2.3	1.9	1.7	2.0	1.9	1.9	1.9	1.7	1.9	1.7	0.6	0.5
Ever had hysterectomy (womb removed)	0.6	0.7	2.5	0.6	0.8	0.6	0.5	0.8	1.5	0.7	1.0	1.6	0.6	0.6	0.7	0.5	0.7	0.5	0.6	0.9	0.9
Townsend deprivation index at recruitment	0.6	0.9	2.4	-1.4	-1.2	-0.9	-0.7	1.5	0.7	-0.9	-1.2	-0.3	-0.9	-0.7	-0.9	-0.7	-0.9	-0.8	0.1	1.1	0.1
Supplements: Glucosamine	0.6	0.8	1.5	1.1	1.1	1.0	0.9	0.5	0.6	1.2	1.0	0.2	0.9	0.9	1.0	0.9	0.9	0.9	0.7	0.1	0.8
Nervous feelings	0.6	1.1	4.0	-0.6	-0.2	-0.9	-1.1	-1.9	-2.0	-1.0	-0.6	-1.1	-0.9	-1.0	-0.8	-0.9	-0.6	-0.8	-0.4	-1.3	-0.7
Had other major operations	0.6	0.7	1.3	-1.1	-0.9	-1.0	-0.9	-0.3	-0.1	-1.2	-0.9	-0.3	-1.0	-1.0	-1.1	-1.0	-0.7	-0.9	-0.7	0.1	-0.8
Mouth/teeth dental problems	0.6	0.8	4.3	-0.3	-0.6	0.3	0.6	1.9	2.1	0.1	0.4	1.3	0.5	0.6	0.3	0.4	0.4	0.2	0.3	1.8	0.6
Illnesses of siblings	0.6	0.9	5.2	-0.0	-0.3	-0.7	-0.7	-1.5	-1.2	-0.7	-1.0	-0.8	-0.8	-0.8	-0.8	-0.7	-0.8	-0.5	0.3	-2.3	-0.3
Trunk fat-free mass	0.6	3.5	14.7	1.5	0.9	1.5	1.7	3.0	2.3	1.2	1.1	3.8	1.5	1.6	1.3	1.4	0.9	1.5	-0.8	3.4	-0.6
Alcohol intake versus 10 years previously	0.6	0.9	1.4	1.2	0.4	1.1	1.0	1.1	0.9	1.1	0.8	0.8	1.1	1.0	1.0	1.1	0.7	1.2	-0.6	0.9	0.1
Hair/balding pattern: Pattern 3	0.6	0.9	1.7	0.6	-0.9	1.1	1.1	1.1	1.2	0.9	0.9	0.7	1.3	1.2	1.1	1.1	0.8	1.0	0.3	0.2	-0.9
Impedance of arm (left)	0.6	2.6	12.7	-1.0	-0.7	-1.1	-1.4	-2.3	-2.8	-1.0	-0.9	-3.6	-1.1	-1.2	-1.1	-1.0	-0.7	-1.1	-0.4	-2.7	-0.8
Trunk predicted mass	0.6	3.6	14.8	1.5	0.9	1.5	1.7	3.0	2.3	1.2	1.1	3.9	1.5	1.6	1.3	1.4	0.9	1.5	-0.9	3.4	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	4.9	0.6	-0.1	0.4	0.4	1.5	1.0	0.4	0.1	1.9	0.4	0.5	0.3	0.3	0.0	0.6	-0.7	2.2	-1.3
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.2	-0.1	0.4	-0.8	-0.8	-1.2	-1.0	-0.8	-0.9	-0.0	-0.8	-0.9	-0.8	-0.9	-0.9	-0.7	-1.3	-1.5	-1.0
Headache pain in last month	0.6	1.0	4.0	0.3	1.1	0.9	0.7	0.6	0.2	0.7	1.1	1.4	0.7	0.8	0.9	0.9	0.8	0.7	2.0	1.3	1.1
Qualifications: College or University degree	0.6	1.8	4.5	-2.1	-0.2	-1.5	-1.6	-1.5	-1.8	-1.1	-0.6	-1.2	-1.5	-1.6	-1.5	-1.3	-0.5	-1.8	0.3	-1.5	0.8
Chest pain or discomfort	0.6	0.9	3.6	0.7	0.7	0.7	0.8	0.8	0.9	0.2	0.9	1.9	0.6	0.7	0.6	0.6	0.7	0.6	-1.3	1.7	-0.8
Age at last live birth	0.6	0.9	2.9	-0.3	1.1	-0.7	-1.0	-1.6	-1.6	-0.6	-0.2	-0.2	-1.1	-1.0	-1.1	-0.7	-0.4	-0.7	-1.7	-0.2	0.5
Medication: Aspirin	0.6	0.8	5.9	0.6	2.4	0.4	0.4	-0.7	-0.1	0.3	0.4	0.1	0.1	0.3	0.2	0.3	0.5	0.6	2.0	-0.4	1.5
Illnesses of siblings: Diabetes	0.6	0.8	5.6	-0.6	-1.4	-0.2	-0.3	0.6	0.1	-0.2	-0.5	0.8	-0.2	-0.2	-0.2	-0.3	-0.9	-0.3	-2.4	0.6	-1.7
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.3	1.4	0.5	1.3	0.9	-0.6	-0.3	1.5	1.0	-0.6	1.2	1.1	1.3	1.1	0.7	1.3	1.1	-0.6	0.3
Back pain experienced in last month	0.6	0.9	2.5	1.0	-0.1	0.8	0.8	1.5	0.5	0.2	0.8	1.4	0.9	0.9	0.8	0.9	0.9	0.6	-0.1	1.6	-1.2
Medication: Bendroflumethiazide	0.6	1.0	5.1	0.4	0.6	0.8	0.8	1.0	1.4	0.7	1.1	2.3	0.9	0.8	1.0	0.8	0.9	0.6	-0.8	1.2	-0.2
Unable to work because of sickness or disability	0.6	0.7	5.2	0.2	-0.9	-0.5	-0.5	0.3	-0.4	-0.8	-1.0	0.4	-0.5	-0.4	-0.7	-0.6	-1.2	-0.2	-1.3	0.6	-2.3
Pack years of smoking	0.6	0.9	2.9	1.2	0.3	0.7	0.8	1.7	1.4	1.1	0.3	1.0	0.6	0.8	0.7	0.8	0.6	1.1	1.5	0.8	0.2
Neuroticism (Nagel 2018)	0.5	1.2	2.2	1.0	-0.1	1.1	1.1	1.1	1.2	1.1	1.2	1.5	1.3	1.2	1.0	1.1	1.5	1.1	0.4	1.3	-0.7
Prostate Cancer	0.5	0.7	1.6	0.9	0.6	0.8	0.6	0.7	1.1	0.5	1.1	0.8	0.8	0.7	0.8	0.8	1.1	0.7	-0.2	1.3	-0.6
HDL Cholesterol	0.5	0.8	4.5	-0.9	1.0	-0.5	-0.6	-1.4	-1.0	-0.4	-0.4	-2.1	-0.7	-0.7	-0.5	-0.5	-0.5	-0.4	0.5	-0.6	1.6
Neuroticism (2016)	0.5	0.7	1.8	0.6	-1.2	0.5	0.7	1.3	0.9	0.3	0.1	1.2	0.7	0.7	0.3	0.7	0.3	0.6	-0.9	1.3	-1.3
Blood Eosinophil Count	0.5	3.9	7.3	-1.9	-1.2	-2.0	-1.8	-2.2	-2.1	-2.3	-2.5	-1.3	-2.0	-2.0	-2.0	-2.1	-2.7	-2.0	-2.3	-1.2	-1.1
Respiratory disease	0.5	1.2	2.4	-1.5	-0.3	-1.1	-1.0	-1.5	-0.9	-1.6	-0.9	-0.8	-1.1	-1.1	-0.9	-1.1	-1.1	-1.3	-1.4	-0.2	-0.2
Qualifications: CSEs or equivalent	0.5	0.6	3.6	0.7	1.9	0.6	0.4	-0.5	-0.8	0.5	0.2	-0.4	0.3	0.5	0.3	0.5	0.4	0.8	1.7	-0.8	0.7
Noisy workplace	0.5	0.6	2.6	-0.0	-0.7	-0.4	-0.7	-0.8	-1.0	-0.3	-0.3	0.8	-0.4	-0.5	-0.4	-0.6	-0.9	-0.4	-1.6	-0.4	-1.6
Medication: Lansoprazole	0.5	0.6	2.3	0.9	0.5	0.8	0.6	0.9	0.9	0.9	0.7	0.8	0.6	0.7	0.6	0.6	0.5	0.8	0.5	1.5	0.7
Gout (self-reported)	0.5	0.6	4.2	-0.5	-1.8	-0.5	-0.2	1.0	0.2	-0.4	-0.6	0.3	-0.2	-0.4	-0.4	-0.2	-0.2	-0.4	-1.0	-0.1	-2.1
Medication: Ventolin 100micrograms inhaler	0.5	0.6	5.4	-0.4	-0.3	0.0	0.1	-0.4	-0.8	-0.2	-0.1	-0.6	0.1	0.0	0.0	0.0	-0.5	-0.0	-1.9	0.1	-2.3
High blood pressure (siblings)	0.5	0.7	2.3	0.4	1.0	0.8	0.8	0.8	0.7	0.8	0.9	0.9	0.8	0.9	0.9	0.8	0.6	0.7	-0.1	1.5	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.0	0.7	0.8	0.8	1.0	0.4	1.4	0.6	0.6	0.2	0.8	0.8	0.9	0.7	0.6	0.8	0.4	0.6	1.0
Pulse rate, automated reading	0.5	1.6	5.4	-0.2	-1.3	0.8	0.9	2.1	2.1	0.9	1.2	1.7	1.1	1.0	1.0	1.1	1.3	0.6	-0.3	2.3	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	3.3	0.3	-0.3	0.4	0.6	1.8	1.5	0.5	0.4	0.4	0.6	0.6	0.4	0.6	0.7	0.5	-0.1	1.4	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.9	0.6	0.9	0.8	0.8	0.3	0.4	0.9	0.9	1.7	0.8	0.8	0.7	0.6	0.7	0.6	0.2	0.3	0.1
Illnesses of father: Heart disease	0.5	0.7	1.4	-0.9	0.6	-0.8	-0.9	-1.2	-0.6	-0.8	-0.7	0.5	-1.0	-1.0	-0.8	-1.0	-0.9	-0.9	-1.1	0.2	-0.0
Mood swings	0.5	0.9	2.9	0.9	0.6	1.0	1.1	0.4	1.5	0.8	0.9	1.7	1.0	1.0	1.0	0.9	1.0	1.1	0.6	0.9	0.0
Osteoarthritis (self-reported)	0.5	0.6	2.7	1.0	0.9	0.7	0.8	0.4	0.4	0.5	0.5	1.7	0.5	0.7	0.8	0.7	0.4	0.8	1.2	0.3	0.4
Guilty feelings	0.5	0.7	2.6	0.0	-1.2	0.6	0.7	1.4	1.3	0.2	-0.0	1.6	0.6	0.6	0.4	0.4	-0.1	0.6	-0.5	1.5	-0.9
Medication: Atorvastatin	0.5	0.6	1.3	-1.1	-0.3	-0.7	-0.5	-0.1	0.4	-1.0	-1.0	-0.9	-0.8	-0.6	-0.7	-0.8	-0.9	-0.8	-1.1	0.5	0.4
Age started oral contraceptive pill	0.5	0.7	3.6	-1.0	0.3	-0.7	-0.7	-0.1	-0.2	-0.6	-0.5	-0.4	-0.9	-0.8	-0.7	-0.5	-0.4	-0.8	1.9	-0.5	1.5
Alzheimer’s Disease (in father)	0.4	0.5	4.7	0.5	1.5	0.1	-0.0	0.6	-0.1	0.4	0.5	0.7	-0.1	0.1	0.1	0.2	0.6	-0.0	2.2	-0.0	0.0
Bipolar Disorder (2011)	0.4	0.4	2.5	0.0	0.5	-0.1	-0.4	-1.6	-1.2	-0.1	-0.2	-0.3	-0.3	-0.3	-0.1	-0.4	-0.6	-0.1	-0.2	-1.1	0.6
Crohns Disease (2012)	0.4	0.6	1.2	1.0	0.8	0.7	0.5	0.7	1.0	0.9	0.9	0.9	0.6	0.6	0.8	0.6	0.7	0.6	0.1	1.1	0.7
Rheumatoid Arthritis	0.4	0.6	1.7	0.2	1.3	0.6	0.4	0.5	0.3	0.7	1.2	0.9	0.6	0.6	0.7	0.7	1.1	0.4	0.2	1.0	1.2
Relative age of first facial hair	0.4	0.7	1.9	1.4	0.2	0.8	0.7	1.2	0.8	1.2	0.9	-0.4	0.9	0.8	0.8	1.0	1.0	0.8	0.4	0.5	-0.3
Supplements: Zinc	0.4	0.4	2.9	-0.0	-0.1	0.3	0.4	1.2	1.7	0.4	0.2	0.2	0.4	0.4	0.3	0.2	0.2	0.3	0.7	0.5	1.1
Diabetes (father)	0.4	0.5	1.1	-0.7	0.8	-0.6	-0.7	-0.8	0.0	-0.6	-0.9	-0.7	-0.8	-0.7	-0.6	-0.7	-1.1	-0.4	-0.5	-0.7	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	3.0	0.1	1.4	0.2	0.4	0.3	1.1	-0.1	-0.3	1.7	-0.0	0.2	0.2	0.0	-0.5	0.2	0.3	1.7	0.4
Relative age voice broke	0.4	0.7	4.8	1.0	-0.8	0.0	0.0	1.3	0.6	0.0	0.3	0.3	0.4	0.1	-0.0	0.3	0.5	-0.0	-1.5	1.0	-2.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	2.2	-0.5	0.9	0.2	0.1	0.7	0.5	0.1	0.5	0.3	-0.0	0.3	0.2	0.2	0.6	0.1	1.5	1.1	1.4
Hayfever, allergic rhinitis or eczema	0.4	0.8	2.5	-0.6	1.3	-0.7	-0.9	-1.6	-0.4	-0.6	-0.4	1.3	-0.9	-0.8	-0.7	-0.9	-0.8	-0.7	-1.1	-0.5	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	2.7	0.7	1.6	0.6	0.7	0.0	1.1	0.5	1.0	1.0	0.5	0.6	0.7	0.6	1.2	0.5	0.8	1.2	1.5
Depression (self-reported)	0.4	0.4	1.5	0.1	0.2	0.6	0.8	0.8	0.5	0.3	-0.5	1.2	0.4	0.6	0.4	0.5	-0.6	0.8	0.4	0.8	-1.1
Lung cancer (father)	0.4	0.5	2.5	0.1	1.6	0.5	0.5	0.1	-0.7	0.5	0.4	0.8	0.3	0.5	0.6	0.5	0.3	0.5	1.4	0.7	0.9
Birth weight of first child	0.4	0.7	2.2	1.1	-0.1	0.7	0.6	-0.9	-0.9	0.8	1.1	-0.1	0.9	0.6	0.7	0.8	1.5	0.7	0.3	-1.0	-0.9
Exposure to tobacco smoke outside home	0.4	0.6	2.7	0.9	0.4	0.5	0.8	0.8	1.1	0.4	-0.0	1.4	0.5	0.5	0.5	0.4	0.0	0.7	-0.2	1.6	-0.6
Comparative body size at age 10	0.4	1.2	8.0	0.2	-0.6	0.4	0.8	2.1	2.8	-0.0	-0.0	1.6	0.7	0.7	0.2	0.4	0.4	0.5	0.5	1.9	-0.7
Eye problems/disorders: Cataract	0.4	0.4	1.3	-1.1	0.5	-0.8	-0.9	-0.6	0.0	-0.4	0.2	0.5	-0.6	-0.8	-0.6	-0.9	-0.1	-1.1	0.5	0.1	-0.2
Hearing aid user	0.4	0.4	1.1	-0.6	-0.4	-0.6	-0.7	-0.7	-0.2	-0.5	-0.8	-0.6	-0.7	-0.8	-0.7	-0.8	-0.9	-0.7	0.5	-1.0	0.3
Commuting to job workplace: Public transport	0.4	0.5	2.4	0.1	-0.2	-0.3	-0.1	1.2	0.0	-0.1	-0.5	-1.5	-0.4	-0.2	-0.2	-0.1	0.1	-0.1	1.1	0.8	1.4
Illnesses of father: High blood pressure	0.4	0.5	2.8	-0.2	-1.7	-0.3	-0.3	0.3	0.8	-0.5	-0.2	-0.8	0.1	-0.1	-0.2	-0.1	0.1	-0.3	-1.3	0.2	-1.5
Number of operations (self-reported)	0.4	0.6	1.5	0.4	1.1	0.7	0.6	-0.3	0.3	0.7	1.2	0.9	0.6	0.6	0.7	0.7	1.2	0.6	0.5	1.0	0.7
Risk taking	0.4	0.7	1.8	-0.5	-1.0	-0.9	-0.8	0.1	-0.4	-0.8	-1.0	0.4	-0.9	-0.9	-1.0	-0.9	-1.0	-0.8	-1.3	-0.3	-0.5
Bipolar Disorder (2018)	0.3	0.4	2.4	-0.2	0.5	-0.5	-0.4	-1.6	-0.4	-0.4	-0.8	-0.5	-0.5	-0.5	-0.5	-0.6	-1.0	-0.3	-0.1	-0.9	-0.6
Depressed Affect (Nagel 2018)	0.3	0.6	3.0	0.6	-0.2	0.6	0.6	0.7	1.0	0.4	0.5	1.7	0.7	0.7	0.5	0.6	0.9	0.6	0.7	1.1	-0.6
Worry (Nagel 2018)	0.3	0.7	1.1	0.7	-0.2	0.9	0.9	0.5	0.1	0.9	0.9	1.0	1.1	0.9	0.9	1.0	1.0	0.8	-0.0	0.9	-1.1
Alzheimer’s Disease (including proxy)	0.3	0.4	2.9	-0.1	1.7	-0.1	-0.2	-0.9	-0.6	-0.2	0.3	0.2	-0.3	-0.3	-0.1	-0.2	0.3	-0.2	1.1	-0.8	1.0
Crohns Disease (2017)	0.3	0.6	2.5	0.5	1.2	0.7	0.5	0.5	1.0	0.6	0.5	1.6	0.5	0.6	0.7	0.5	0.1	0.5	0.4	0.7	1.2
Breast Cancer	0.3	0.7	2.5	0.2	0.4	0.8	1.0	0.4	1.1	0.3	0.8	0.2	0.9	0.9	1.0	0.7	0.4	0.6	1.4	0.1	1.6
Allergy or Eczema	0.3	0.7	3.8	-0.6	0.5	-0.7	-0.8	-0.7	0.6	-0.9	-0.5	1.9	-0.8	-0.7	-0.8	-0.8	-0.6	-0.7	-1.1	0.4	-0.0
Sensitivity / hurt feelings	0.3	0.5	2.1	0.3	0.7	0.5	0.7	0.7	1.4	0.5	0.6	0.5	0.4	0.5	0.4	0.5	0.7	0.4	1.4	0.4	0.5
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	2.9	-0.6	0.4	0.1	-0.0	-0.4	-0.2	0.2	0.4	0.5	0.2	0.1	0.3	-0.0	0.0	-0.1	-1.7	1.0	-0.4
Medication for hormone replacement therapy	0.3	0.4	1.3	-0.4	-0.6	-0.5	-0.6	-0.4	-1.0	-0.3	-0.1	-1.0	-0.4	-0.5	-0.5	-0.3	0.1	-0.5	-0.1	-1.0	-1.1
Average weekly fortified wine intake	0.3	0.3	4.6	0.0	0.4	0.2	0.0	-0.2	-0.8	0.3	0.1	-2.1	0.1	0.1	0.1	0.2	-0.1	0.2	-0.1	-0.5	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	3.4	0.9	1.9	0.5	0.4	-0.4	0.4	0.6	0.9	0.9	0.3	0.5	0.5	0.4	1.0	0.5	0.6	0.2	1.6
Hair/balding pattern: Pattern 2	0.3	0.4	1.4	0.7	1.2	0.7	0.7	0.2	0.5	0.5	0.6	0.6	0.6	0.7	0.6	0.7	0.5	0.7	-0.1	0.3	1.0
Medication: Ramipril	0.3	0.4	1.2	-0.2	0.9	-0.6	-0.4	-0.6	0.4	-0.9	-0.9	-0.1	-0.8	-0.5	-0.7	-0.8	-0.8	-0.5	1.1	-0.2	0.2
Number of live births	0.3	0.4	2.6	0.4	1.6	0.5	0.4	-0.3	-0.2	0.2	0.5	0.3	0.2	0.3	0.4	0.3	0.4	0.6	-0.3	1.2	1.4
Happiness	0.3	0.3	1.7	-0.4	0.7	0.3	0.3	0.7	0.7	0.3	0.4	0.8	0.1	0.3	0.2	0.4	0.3	0.3	1.3	0.5	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	2.3	-0.4	-0.7	0.2	0.3	0.1	0.3	0.5	0.5	-1.4	0.4	0.2	0.3	0.3	0.5	-0.0	-1.5	0.1	-0.6
Mouth/teeth dental problems: Dentures	0.3	0.6	1.9	-0.6	0.3	-0.7	-0.8	-1.2	-1.4	-0.6	-0.5	-1.0	-0.9	-0.9	-0.7	-0.8	-0.5	-0.6	0.2	-0.6	0.4
Breastfed as a baby	0.3	0.4	4.9	-0.3	1.2	0.1	-0.0	-0.1	0.3	-0.1	0.3	0.2	-0.2	-0.0	0.1	0.0	0.4	-0.1	0.5	-0.4	2.2
Worry too long after embarrassment	0.3	0.5	2.0	-0.5	-0.5	-0.5	-0.7	-1.3	-1.1	-0.3	-0.4	-0.3	-0.5	-0.6	-0.7	-0.7	-0.6	-0.5	-0.4	-1.4	-0.4
Medication: Seretide 50 evohaler	0.3	0.3	1.5	-0.6	0.1	-0.2	-0.3	-1.2	-1.0	-0.5	-0.3	-0.9	-0.4	-0.3	0.0	-0.3	-0.5	-0.4	-0.2	-0.8	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.8	0.4	-0.1	0.5	0.4	0.9	0.4	0.3	0.7	0.6	0.5	0.5	0.6	0.6	0.7	0.4	0.4	0.7	-0.3
Alcohol drinker status: Never	0.3	0.4	1.9	-0.7	1.2	-0.0	0.0	-0.6	-0.7	-0.2	0.1	0.0	-0.3	-0.2	-0.2	-0.1	0.1	-0.2	1.1	-0.6	1.4
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.8	-0.8	0.4	-0.9	-1.0	-0.1	-0.7	-0.7	-0.2	-1.4	-0.8	-0.8	-0.9	-0.8	-0.1	-0.9	-0.4	-0.4	-0.4
Ulcerative Colitis (UC)	0.2	0.3	0.9	-0.7	0.3	-0.6	-0.6	0.0	-0.9	-0.5	-0.4	0.0	-0.7	-0.5	-0.5	-0.6	-0.5	-0.6	0.8	-0.7	0.7
Ovarian Cancer	0.2	0.2	2.0	-0.5	0.0	-0.0	-0.1	-0.4	-0.6	0.3	0.4	1.4	0.0	0.0	0.2	-0.0	0.4	-0.0	0.6	-0.1	0.8
LDL Cholesterol	0.2	0.3	1.9	0.7	-0.7	0.1	-0.1	-0.0	0.1	0.1	0.5	0.0	0.3	0.1	0.2	0.1	0.5	0.0	-1.3	0.3	-1.4
Schizophrenia (2014)	0.2	0.4	0.9	1.0	0.9	0.7	0.6	0.6	0.3	0.3	0.1	0.6	0.6	0.6	0.5	0.5	-0.1	0.8	0.2	0.8	0.8
Hearing difficulty/problems: Yes	0.2	0.4	2.1	0.2	-0.3	0.5	0.3	0.7	0.4	0.5	0.7	-0.2	0.5	0.5	0.5	0.6	0.6	0.3	-1.1	1.5	-0.0
Diabetes (mother)	0.2	0.3	2.6	-0.2	1.3	0.0	-0.1	-0.4	0.3	-0.1	0.3	1.6	-0.1	-0.1	0.2	-0.0	0.2	-0.2	-0.2	0.1	0.3
Severe depression (siblings)	0.2	0.2	1.5	0.0	0.2	-0.1	-0.1	0.3	-0.4	-0.1	-0.4	-1.2	-0.3	-0.1	-0.3	0.0	-0.3	0.2	0.8	0.2	0.8
Fed-up feelings	0.2	0.4	1.0	0.6	0.6	0.5	0.4	0.6	0.7	0.5	0.8	1.0	0.4	0.5	0.3	0.6	1.0	0.5	0.9	0.9	-0.2
Stomach or abdominal pain in last month	0.2	0.3	0.8	-0.7	-0.7	-0.4	-0.3	-0.4	-0.3	-0.3	-0.6	-0.2	-0.4	-0.3	-0.3	-0.5	-0.9	-0.4	-0.7	0.4	-0.9
Number of incorrect matches in round	0.2	0.4	1.4	-0.6	-0.3	-0.5	-0.6	-0.8	-0.3	-0.7	-0.2	-0.8	-0.6	-0.6	-0.5	-0.6	-0.3	-0.7	-0.7	0.3	1.2
Had menopause	0.2	0.3	2.4	-0.5	-1.5	-0.1	-0.1	0.5	0.4	-0.2	-0.1	-0.6	0.1	0.0	-0.1	0.0	-0.1	-0.3	-1.0	0.7	-0.7
Qualifications: None of the above	0.2	0.5	1.5	1.2	-1.0	0.5	0.5	1.0	0.2	0.4	0.4	-0.9	0.6	0.6	0.5	0.7	0.6	0.7	0.5	0.9	-0.5
Fluid intelligence score	0.2	0.3	2.0	-0.9	-0.3	-0.6	-0.5	0.6	-0.3	-0.4	-0.4	-1.4	-0.5	-0.5	-0.8	-0.4	0.0	-0.5	0.4	-0.4	0.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	2.4	0.3	1.2	0.3	0.4	0.6	0.6	-0.1	0.1	1.5	0.2	0.4	0.3	0.2	-0.1	0.4	0.5	1.0	0.1
Pulse rate	0.2	0.3	1.9	-0.8	-1.3	-0.2	-0.3	0.1	-0.1	-0.3	-0.1	0.1	-0.1	-0.2	-0.3	-0.1	-0.2	-0.3	-0.8	0.4	-1.4
Medication: Cholesterol lowering	0.2	0.4	1.5	0.1	0.2	-0.0	0.3	1.1	1.2	-0.1	-0.5	1.2	-0.2	0.1	-0.2	-0.1	-0.4	0.2	-0.3	1.0	-0.5
Illnesses of mother	0.2	0.3	1.1	-0.0	0.7	-0.2	-0.1	-0.2	0.3	-0.1	-0.9	1.0	-0.4	-0.2	-0.4	-0.4	-1.1	0.1	-0.4	0.1	0.5
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.0	-0.2	-0.9	-0.3	-0.3	0.2	-0.5	-0.5	-0.4	-1.0	-0.2	-0.2	-0.2	-0.2	-0.3	-0.3	-1.0	0.6	-0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.1	1.0	0.4	0.8	0.6	0.6	0.4	0.6	0.8	-0.3	0.7	0.6	0.7	0.7	0.8	0.6	0.1	0.9	0.6
Number of full brothers	0.2	0.2	1.6	-0.6	0.7	-0.2	-0.3	0.5	0.1	-0.1	-0.3	-0.2	-0.4	-0.3	-0.2	-0.4	-0.6	-0.3	0.2	0.5	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	3.9	-0.0	0.2	-0.0	0.0	0.4	0.5	-0.1	-0.2	2.0	-0.1	-0.0	-0.1	-0.2	-0.4	0.2	-0.4	0.6	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	2.1	0.2	-0.9	0.0	-0.0	-0.0	-0.7	0.2	0.0	-1.4	0.1	0.0	0.0	0.2	0.3	0.2	0.4	-0.4	-0.5
Eye problems/disorders: None of the above	0.2	0.2	1.1	0.2	0.4	0.0	0.1	0.1	-0.8	-0.2	-0.2	-0.9	-0.2	0.0	-0.1	0.1	0.0	0.1	0.5	-1.1	0.4
Medication: Allopurinol	0.2	0.3	1.8	-0.2	-1.3	-0.4	-0.3	0.7	0.0	-0.3	-0.3	-0.5	-0.3	-0.4	-0.3	-0.1	0.1	-0.4	-0.8	-0.1	-1.3
Comparative height size at age 10	0.2	1.1	2.3	-1.0	0.6	-1.0	-0.9	-1.0	-1.3	-1.3	-1.1	0.3	-1.1	-1.0	-1.0	-1.1	-1.4	-1.0	-0.6	-0.4	-1.5
Had major operations	0.2	0.3	1.7	0.5	0.4	0.4	0.5	-0.1	-0.1	0.3	0.6	1.3	0.5	0.4	0.5	0.3	0.5	0.3	-0.2	1.0	-0.1
Family relationship satisfaction	0.2	0.3	3.5	0.5	-0.7	0.2	0.1	0.1	-0.3	0.2	0.1	-0.1	0.3	0.2	0.2	0.3	0.0	0.3	-0.2	-0.4	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	4.0	0.2	2.0	0.2	0.1	0.0	0.5	0.0	-0.0	0.8	-0.0	0.1	0.1	0.0	-0.3	0.2	0.8	0.1	0.3
Loneliness, isolation	0.2	0.2	1.3	0.5	0.4	-0.3	-0.2	0.3	1.1	-0.5	-0.2	0.5	-0.3	-0.2	-0.1	-0.3	-0.2	-0.3	0.5	0.8	-0.4
Friendships satisfaction	0.2	0.2	0.7	-0.5	0.4	-0.3	-0.4	-0.1	0.2	-0.4	-0.2	-0.8	-0.4	-0.3	-0.4	-0.2	-0.2	-0.3	0.7	0.2	0.8
Qualifications: nursing, teaching	0.2	0.3	0.7	-0.2	0.6	0.6	0.5	0.1	0.1	0.5	0.7	0.1	0.5	0.6	0.8	0.6	0.5	0.4	0.3	0.8	0.9
Illnesses of father: None of the above (group 1)	0.2	0.2	0.7	-0.2	-0.8	-0.2	-0.1	0.0	-0.4	-0.2	-0.7	-0.4	-0.3	-0.1	-0.3	-0.3	-0.7	-0.1	0.8	-0.6	0.3
Average weekly champagne plus white wine intake	0.2	0.3	2.3	-0.2	-1.5	-0.2	-0.2	0.2	-0.2	-0.1	-0.4	0.0	0.1	-0.1	-0.2	-0.1	-0.3	-0.1	-1.1	-0.2	-1.3
Miserableness	0.2	0.4	2.0	-0.3	-0.8	-0.4	-0.4	-0.5	-0.3	-0.7	-0.9	-0.1	-0.3	-0.3	-0.6	-0.5	-0.9	-0.3	-0.9	-0.2	-1.4
Average weekly beer plus cider intake	0.2	0.3	2.0	0.4	-0.7	0.1	-0.0	-0.4	-0.6	0.4	0.1	-1.3	0.1	-0.0	-0.0	0.3	0.3	0.3	0.4	-1.4	-0.4
Heart disease (siblings)	0.2	0.3	1.2	-0.6	0.9	-0.1	-0.0	0.5	0.6	-0.1	0.2	1.1	-0.2	0.0	0.0	-0.2	0.1	-0.3	0.8	1.0	0.8
Alcohol drinker status: Previous	0.2	0.3	0.9	0.4	0.6	0.6	0.7	0.2	0.6	0.4	0.1	0.5	0.6	0.7	0.6	0.5	-0.1	0.7	0.9	0.0	0.3
Schizophrenia (2018)	0.1	0.2	0.8	0.9	0.2	0.6	0.6	0.5	0.3	0.2	-0.0	0.4	0.5	0.5	0.4	0.4	-0.1	0.6	0.0	0.9	0.6
Irritable Bowel Disease (IBD)	0.1	0.3	1.7	-0.3	1.0	0.1	0.0	0.3	-0.0	0.1	0.1	1.1	-0.0	0.1	0.2	0.0	-0.2	0.0	0.7	-0.0	1.3
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.7	-0.1	0.0	0.1	0.2	0.8	0.2	0.5	0.3	-0.8	0.2	0.3	0.0	0.3	0.6	0.2	-0.3	0.3	-0.1
Lupus	0.1	0.2	1.0	-0.1	-0.5	-0.0	0.2	-0.8	0.7	0.2	-0.3	-0.1	0.2	-0.0	0.1	-0.1	-0.3	-0.1	-0.8	-1.0	-0.6
Triglycerides	0.1	0.1	0.5	0.5	0.3	0.1	-0.0	-0.2	0.0	0.0	0.6	0.3	0.3	0.1	0.3	0.3	0.7	0.1	-0.5	0.2	-0.7
Ulcerative Colitis	0.1	0.2	0.8	0.3	0.9	0.3	0.2	0.3	-0.4	0.2	0.3	0.8	0.1	0.3	0.3	0.3	0.2	0.3	0.9	0.0	0.6
Blood Red Count	0.1	1.3	6.6	0.4	2.6	0.6	0.2	-0.1	0.8	0.8	1.2	2.3	0.3	0.4	0.5	0.4	1.1	0.4	1.4	1.2	1.5
Blood White Count	0.1	1.1	3.1	-1.5	-0.5	-1.0	-0.9	-1.2	-0.9	-1.1	-1.3	-0.8	-1.0	-0.9	-1.0	-1.1	-1.3	-0.9	-1.8	0.1	0.2
Height	0.1	1.6	5.2	-0.6	0.9	-1.1	-1.5	-1.7	-2.3	-1.2	-0.8	-0.7	-1.2	-1.3	-1.3	-1.3	-1.1	-1.2	-0.9	-1.3	-1.0
Hypothyroidism (self reported)	0.1	0.2	1.5	0.0	0.4	-0.1	-0.1	0.4	0.5	-0.3	-0.1	-0.8	-0.2	-0.2	-0.2	-0.2	-0.1	-0.2	0.9	0.3	1.2
Neuroticism	0.1	0.2	1.7	-0.2	-1.2	0.0	0.2	0.6	0.3	-0.2	-0.3	0.4	0.2	0.2	-0.0	0.2	-0.1	0.0	-0.1	0.5	-1.3
Chronotype (morning person)	0.1	0.3	1.3	0.1	-0.9	0.2	0.4	1.2	0.9	0.4	-0.0	0.7	0.3	0.3	0.1	0.3	0.1	0.3	1.0	0.1	-0.4
Tanning	0.1	1.5	6.2	1.6	0.8	0.7	1.2	2.2	1.9	0.3	-0.2	2.5	0.6	0.8	0.6	0.6	0.0	1.0	0.7	2.0	-0.4
Hand grip strength (left)	0.1	0.1	1.0	0.1	-0.2	-0.2	-0.4	-0.1	-0.6	0.2	0.3	0.5	-0.1	-0.2	-0.2	-0.2	0.2	-0.2	-0.4	-0.1	-1.0
Hand grip strength (right)	0.1	0.3	2.2	0.9	0.6	0.4	0.2	0.4	0.3	0.6	0.8	1.5	0.4	0.3	0.4	0.4	0.6	0.3	0.1	0.6	-0.2
Maternal smoking around birth	0.1	0.1	0.5	0.5	-0.7	0.2	0.1	0.1	0.2	0.5	-0.0	0.0	0.3	0.3	0.2	0.2	-0.1	0.4	-0.2	-0.1	0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.3	-0.1	-0.4	0.1	0.2	-0.4	-0.1	-0.0	0.0	-0.5	0.3	0.2	0.3	0.2	0.1	0.2	0.1	0.1	0.2
Serious illness, injury or assault to yourself	0.1	0.2	1.1	-0.3	0.2	-0.1	-0.2	-0.1	0.8	-0.1	0.1	1.0	-0.2	-0.2	-0.1	-0.2	-0.2	-0.3	-0.3	0.7	0.0
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	1.5	-0.1	1.2	0.2	0.1	0.3	-0.1	0.1	0.1	0.5	-0.0	0.1	0.1	-0.0	-0.1	0.0	0.7	0.4	0.8
Medication: Atenolol	0.1	0.1	0.5	0.4	-0.0	0.1	0.2	0.7	0.6	-0.2	0.3	0.6	0.2	0.1	0.1	0.1	0.5	0.2	-0.2	0.2	-0.2
Medication: Levothyroxine sodium	0.1	0.2	0.8	0.4	0.4	0.1	-0.1	0.4	0.3	0.1	0.6	-0.8	0.1	0.0	0.3	0.1	0.6	-0.1	0.4	0.9	0.5
Sitting height	0.1	0.4	1.3	-1.0	0.4	-0.4	-0.2	0.7	0.5	-0.7	-0.4	0.8	-0.4	-0.3	-0.4	-0.4	-0.5	-0.7	-0.9	1.2	-0.3
Pain all over the body in last month	0.1	0.1	0.8	0.6	0.9	0.2	0.0	-0.1	0.5	0.2	0.1	0.6	-0.1	0.0	-0.1	-0.1	-0.1	0.2	-0.6	0.4	0.6
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.9	-0.3	-0.1	-0.3	-0.6	-0.5	0.2	-0.3	0.3	0.9	-0.4	-0.4	-0.4	-0.4	0.3	-0.4	0.1	-0.1	0.0
Neuroticism score	0.1	0.2	2.0	-0.1	-0.4	-0.2	-0.2	-0.2	0.2	-0.3	-0.2	0.6	-0.2	-0.1	-0.3	-0.2	-0.1	-0.2	0.0	0.0	-1.4
Tense / ‘highly strung’	0.1	0.2	0.7	0.3	0.7	0.0	-0.1	-0.8	-0.4	0.2	0.0	-0.6	-0.1	-0.1	-0.0	-0.0	-0.0	0.1	0.9	-0.8	0.2
Hair/balding pattern: Pattern 4	0.1	0.2	0.7	-0.3	0.2	-0.4	-0.1	-0.1	-0.2	-0.4	-0.8	0.1	-0.6	-0.4	-0.4	-0.5	-0.9	-0.3	0.8	0.4	-0.2
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.5	0.3	-0.7	0.5	0.4	0.4	-0.2	0.4	0.7	-0.2	0.7	0.5	0.7	0.7	0.7	0.4	-0.5	0.4	-0.2
Chronic bronchitis/emphysema (mother)	0.1	0.1	1.2	-0.1	-0.1	0.1	-0.0	-0.3	-0.6	-0.0	0.5	-1.1	0.1	-0.0	0.1	0.1	0.6	-0.1	-0.4	-0.1	0.0
Medication: Blood pressure	0.1	0.2	0.9	0.2	0.9	-0.2	-0.2	-0.6	-0.1	-0.3	-0.3	0.1	-0.4	-0.3	-0.3	-0.5	-0.5	-0.2	0.5	-0.4	0.1
Number of full sisters	0.1	0.1	0.5	0.3	-0.3	-0.1	-0.1	0.6	-0.1	-0.2	-0.6	0.7	-0.2	-0.1	-0.2	-0.1	-0.4	-0.0	0.3	-0.1	-0.4
Suffer from ‘nerves’	0.1	0.2	1.2	0.4	0.8	0.4	0.2	-0.3	-0.3	0.2	0.1	1.1	0.2	0.3	0.1	0.3	0.1	0.4	0.4	0.0	-0.7
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.8	-0.4	-0.1	0.3	0.3	0.3	0.1	-0.1	0.1	-0.0	0.3	0.4	0.3	0.3	0.3	0.2	0.9	-0.7	-0.3
Breast cancer (self-reported)	0.1	0.1	0.8	0.3	-0.1	0.1	-0.1	-0.2	0.3	0.3	0.2	0.2	-0.0	-0.1	0.1	0.0	0.3	0.2	0.9	0.2	0.6
Wears glasses or contact lenses	0.1	0.1	0.4	-0.3	0.0	0.0	0.2	-0.2	0.7	0.1	0.1	0.2	0.2	0.3	0.3	0.1	0.1	-0.1	0.1	0.3	0.4
Mother’s age at death	0.1	0.1	0.5	-0.7	-0.6	-0.4	-0.3	-0.3	-0.4	-0.3	0.2	-0.1	-0.2	-0.3	-0.3	-0.3	0.1	-0.5	0.4	-0.5	-0.3
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.2	0.4	-0.5	0.3	0.3	-0.1	0.2	-0.1	-0.1	-0.2	0.4	0.4	0.3	0.2	-0.1	0.4	0.3	0.0	0.0
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.8	0.1	-0.5	0.1	0.2	0.4	0.7	0.1	-0.4	0.9	-0.0	0.2	-0.0	-0.0	-0.5	-0.0	0.3	0.7	0.1
Irritability	0.1	0.2	1.7	-0.0	0.3	0.1	-0.1	-0.1	0.8	0.3	0.3	-0.8	0.1	0.1	-0.0	0.0	0.5	-0.0	1.3	-0.5	-0.2
Fractured/broken bones in last 5 years	0.1	0.1	1.0	-0.2	0.5	0.1	0.3	0.3	0.2	-0.1	-0.1	-0.8	0.1	0.3	0.1	0.2	-0.1	0.1	1.0	0.0	0.5
Supplements: Calcium	0.1	0.1	0.5	0.3	-0.1	0.2	0.3	0.7	0.2	0.1	-0.1	0.3	0.2	0.3	0.2	0.1	-0.1	0.2	-0.6	0.6	0.0
Basal cell carcinoma (self-reported)	0.1	0.1	0.6	-0.3	-0.3	0.0	0.1	-0.1	-0.3	0.0	-0.0	-0.8	0.1	0.0	-0.1	0.1	0.0	-0.0	-0.0	-0.5	-0.7
Bipolar Disorder or Schizophrenia	0.0	0.1	0.5	0.5	0.5	0.2	0.2	-0.6	-0.0	-0.1	-0.5	0.0	0.0	0.1	0.0	-0.0	-0.7	0.2	-0.0	0.1	0.1
Blood Platelet Count	0.0	0.1	0.3	-0.0	-0.4	0.2	0.2	-0.6	-0.6	-0.2	-0.4	-0.4	0.1	0.2	0.3	0.1	-0.6	0.2	-0.1	-0.1	0.3
Heel T-Score	0.0	0.3	3.2	0.1	1.8	0.1	0.0	-0.8	-0.4	-0.1	0.3	0.2	-0.2	-0.1	0.0	0.1	0.3	-0.1	0.3	-0.4	1.2
Waist Hip Ratio (WHR)	0.0	0.1	0.8	0.3	0.4	-0.2	-0.4	-0.7	-0.6	-0.2	-0.1	-0.2	-0.3	-0.3	0.0	-0.4	-0.3	-0.2	0.2	-0.9	0.0
Hair Pigment	0.0	1.2	2.7	0.9	-0.1	1.1	1.0	1.2	1.2	1.1	1.4	0.3	1.2	1.2	1.3	1.1	1.4	1.0	0.1	1.7	0.1
Age when periods started (menarche)	0.0	0.1	0.6	-0.5	-0.4	0.0	0.0	-0.0	0.3	0.1	-0.1	0.0	0.2	0.0	-0.1	-0.1	-0.1	-0.1	-0.5	-0.8	0.4
Standing height	0.0	0.4	1.6	-0.2	0.6	-0.4	-0.5	-0.1	-0.9	-0.5	-0.4	0.5	-0.4	-0.4	-0.5	-0.5	-0.7	-0.5	-1.0	0.1	-1.3

Hub : Genes

ARHGEF7

Models

Trait associations