TWAS
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Models
Genes
Traits
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Traits
:
Body mass index (BMI)
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chr15:80,743,350-81,292,020
Best TWAS P=3.13e-08 · Best GWAS P=2.78e-08 conditioned to 0.212
80.8M
80.9M
81M
81.1M
81.2M
81.3M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Prostate Adenocarcinoma
FAM108C1
0.07
0.02
lasso
2
0.02
0.0017
-5.6
-5.5
3.1e-08
0.91
0.01
0.9
TRUE