[Hub]/) : Traits : Body mass index (BMI) :

chr16:86,671-1,137,354

Best TWAS P=1.01e-12 · Best GWAS P=1.16e-11 conditioned to 0.0768

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Nerve Tibial AXIN1 0.11 0.09 lasso 2 0.06 3.9e-05 -6.2 5.5 3.6e-08 -0.78 0.05 0.94 FALSE
2 GTEx Nerve Tibial PDIA2 0.12 0.01 enet 13 0.06 4.4e-05 -6.4 6.9 4.7e-12 -0.77 0.01 0.98 FALSE
3 GTEx Nerve Tibial ARHGDIG 0.13 0.07 lasso 2 0.07 8.0e-06 -6.2 6.1 1.4e-09 -0.74 0.03 0.87 FALSE
4 GTEx Testis RGS11 0.33 0.04 lasso 10 0.08 2.8e-04 -5.8 -5.2 2.6e-07 0.50 0.13 0.14 FALSE
5 GTEx Testis AXIN1 0.36 0.29 lasso 3 0.28 4.3e-13 -6.2 -5.9 4.2e-09 0.81 0.04 0.96 FALSE
6 GTEx Whole Blood NME4 0.12 0.03 lasso 5 0.04 3.0e-04 3.1 6.2 7.6e-10 -0.62 0.02 0.96 FALSE
7 ROSMAP Brain Pre-frontal Cortex PDIA2 0.15 0.07 lasso 8 0.10 5.2e-13 -5.8 -7.0 3.0e-12 0.77 0.03 0.97 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NME4 0.07 0.01 blup 45 0.03 2.3e-04 -5.7 5.4 6.5e-08 -0.51 0.06 0.36 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma AXIN1 0.03 0.01 blup 88 0.01 7.7e-03 -6.2 7.1 1.0e-12 -0.80 0.01 0.75 TRUE
10 The Cancer Genome Atlas Brain Lower Grade Glioma LOC100134368 0.03 0.00 enet 5 0.01 2.8e-02 -2.7 -6.3 3.2e-10 0.58 0.01 0.57 FALSE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LOC100134368 0.08 0.07 blup 48 0.06 1.9e-03 3.1 -5.2 1.8e-07 0.47 0.05 0.15 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma LOC100134368 0.05 0.00 blup 48 0.04 2.5e-05 -5.1 -6.2 6.7e-10 0.65 0.02 0.84 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma LOC100134368 0.06 0.05 blup 47 0.07 3.9e-07 3.1 -6.2 6.9e-10 0.53 0.36 0.52 FALSE