Best TWAS P=1.1e-12 · Best GWAS P=4.95e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | KCNK3 | 0.24 | 0.15 | lasso | 3 | 0.15 | 6.5e-19 | 6.9 | -7.1 | 1.1e-12 | -0.99 | 0.00 | 1.00 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SLC35F6 | 0.05 | 0.04 | enet | 11 | 0.04 | 8.0e-06 | -4.9 | 5.2 | 1.8e-07 | 0.73 | 0.23 | 0.76 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SUPT7L | 0.05 | 0.02 | blup | 28 | 0.04 | 5.2e-05 | 4.5 | 5.3 | 1.3e-07 | 0.10 | 0.00 | 0.90 | TRUE |