[Hub]/) : Traits : Body mass index (BMI) :

chr2:46,117,914-47,543,245

Best TWAS P=9.57e-09 · Best GWAS P=2.81e-10 conditioned to 1.58e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CRIPT 0.12 0.10 lasso 3 0.09 7.1e-08 -5.2 -5.7 9.6e-09 0.41 0.56 0.43 TRUE
2 GTEx Cells EBV-transformed lymphocytes CRIPT 0.28 0.16 enet 10 0.23 5.4e-08 -4.3 -5.5 4.0e-08 0.41 0.61 0.29 FALSE
3 GTEx Esophagus Muscularis CRIPT 0.15 0.21 lasso 4 0.20 2.1e-12 -5.2 -5.2 2.0e-07 0.29 0.57 0.43 FALSE
4 GTEx Muscle Skeletal CRIPT 0.14 0.05 enet 25 0.08 1.8e-08 -4.2 -5.4 7.1e-08 0.36 0.79 0.21 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic PIGF 0.14 0.08 lasso 4 0.07 1.7e-04 -5.5 5.2 1.6e-07 -0.83 0.02 0.97 FALSE
6 NTR Blood CRIPT 0.04 0.05 lasso 6 0.05 3.0e-15 -5.2 5.5 5.0e-08 -0.34 0.56 0.44 FALSE
7 ROSMAP Brain Pre-frontal Cortex CRIPT 0.36 0.31 enet 24 0.32 1.3e-41 -5.2 -5.4 8.5e-08 0.33 0.56 0.44 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma ATP6V1E2 0.13 0.03 blup 76 0.04 3.8e-09 -3.5 5.3 1.1e-07 -0.36 0.02 0.17 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma CRIPT 0.10 0.06 blup 66 0.07 5.6e-05 -4.0 -5.2 2.6e-07 0.33 0.09 0.83 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CRIPT 0.13 0.12 lasso 5 0.11 5.5e-12 -5.2 -5.2 2.6e-07 0.31 0.01 0.99 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma CRIPT 0.13 0.13 lasso 3 0.15 1.2e-15 -4.9 -5.3 1.0e-07 0.37 0.01 0.98 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma CRIPT 0.11 0.10 lasso 4 0.11 1.6e-10 -4.3 -5.2 2.2e-07 0.32 0.02 0.97 FALSE