Best TWAS P=2.6e-10 · Best GWAS P=5.95e-11 conditioned to 0.0421
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | AC015971.2 | 0.09 | 0.03 | lasso | 6 | 0.05 | 0.00091 | 6.4 | -6.3 | 2.6e-10 | -0.89 | 0.01 | 0.95 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | VPS24 | 0.05 | 0.02 | enet | 12 | 0.03 | 0.00029 | 6.4 | -5.2 | 2.1e-07 | -0.65 | 0.00 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | RNF103 | 0.06 | 0.02 | blup | 42 | 0.02 | 0.02420 | -4.9 | 6.1 | 1.3e-09 | 0.86 | 0.02 | 0.43 | FALSE |