[Hub]/) : Traits : Body mass index (BMI) : ← →

chr3:93,537,290-94,472,527

Best TWAS P=1.15e-10 · Best GWAS P=8.13e-21 conditioned to 1.13e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Heart Atrial Appendage PROS1 0.31 0.16 enet 7 0.19 8.4e-09 6.5 -6.1 1.0e-09 -0.68 0.96 0.02 FALSE
2 METSIM Adipose STX19 0.06 0.09 lasso 3 0.08 1.8e-11 5.2 5.7 1.0e-08 0.50 1.00 0.00 FALSE
3 YFS Blood DHFRL1 0.07 0.04 lasso 9 0.04 4.1e-14 5.9 5.6 1.9e-08 0.54 1.00 0.00 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma DHFRL1 0.07 0.05 lasso 1 0.05 3.4e-11 5.1 -5.1 2.8e-07 -0.43 0.98 0.02 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma STX19 0.04 0.02 lasso 1 0.01 5.5e-04 6.3 6.3 3.4e-10 0.64 0.02 0.80 FALSE
6 The Cancer Genome Atlas Glioblastoma Multiforme DHFRL1 0.20 0.12 lasso 8 0.11 3.7e-04 5.1 -5.2 2.0e-07 -0.44 0.01 0.09 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DHFRL1 0.07 0.05 enet 17 0.05 2.5e-06 5.1 -5.9 4.0e-09 -0.54 0.05 0.91 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DHFRL1 0.13 0.07 lasso 2 0.07 5.7e-08 5.1 -5.1 2.8e-07 -0.43 0.96 0.03 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma STX19 0.35 0.11 enet 12 0.20 2.4e-22 6.3 5.8 8.0e-09 0.49 0.03 0.97 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma DHFRL1 0.10 0.06 lasso 2 0.05 5.2e-06 5.1 -5.1 2.8e-07 -0.43 0.94 0.03 FALSE
11 The Cancer Genome Atlas Liver Hepatocellular Carcinoma STX19 0.15 0.08 lasso 1 0.05 1.8e-03 6.3 6.3 3.4e-10 0.64 0.02 0.62 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma ARL13B 0.03 0.00 blup 39 0.00 2.1e-01 -6.7 6.5 1.2e-10 0.66 0.01 0.68 TRUE